PDF(Pubmed)
Abstract：
BACKGROUND: Cancer-related cognitive impairment (CRCI) is commonly experienced by patients with cancer during treatment, and 35% of patients experience cognitive impairment after treatment completion. Impairments in memory, attention, executive functioning, and information processing speed are most reported and often negatively impact daily functioning and quality of life (QoL). Despite the large scale of reports, this adverse side effect is underinvestigated across common cancer types, and there is a lack of insight into the CRCI experience.
OBJECTIVE: This qualitative synthesis aims to explore the evidence in relation to the experience of CRCI across common cancers. It also aims to understand the prevalence of CRCI across various cancer types, cognitive domains, and its impact on QoL and functional ability.
METHODS: A comprehensive search of databases, including PubMed, American Psychological Association PsycINFO, CINAHL, and Scopus, will be conducted. A total of 2 independent reviewers will screen titles and abstracts for inclusion, followed by full-text screening. A third reviewer will resolve any arising conflicts in the process of data screening and inclusion. Subsequently, data extraction and quality assessment using the Critical Appraisal Skills Programme (CASP) tool will be conducted. The results will be analyzed using thematic analysis.
RESULTS: This review is part of a PhD program funded in January 2023. The review commenced in June 2023, and data analysis is currently in progress. The qualitative synthesis will explore the experiences of CRCI across common cancers. The included studies are expected to report on numerous cancer types such as breast cancer, prostate cancer, leukemia, and lung cancer. The included study types are most likely to be interviews, focus groups, and surveys with qualitative components.
CONCLUSIONS: This protocol highlights the need for a qualitative synthesis that will explore the experience of CRCI across common cancer types. It will provide valuable insight into the lived experience of CRCI and the cognitive domains that may be disproportionately affected. There is a growing demand for further management interventions and clinically tested treatments of CRCI and the qualitative exploration of patient experience is crucial for their development. This qualitative synthesis will inform future developments and will contribute to improving QoL after cancer.
UNASSIGNED: DERR1-10.2196/56888.
OBJECTIVE: This qualitative synthesis aims to explore the evidence in relation to the experience of CRCI across common cancers. It also aims to understand the prevalence of CRCI across various cancer types, cognitive domains, and its impact on QoL and functional ability.
METHODS: A comprehensive search of databases, including PubMed, American Psychological Association PsycINFO, CINAHL, and Scopus, will be conducted. A total of 2 independent reviewers will screen titles and abstracts for inclusion, followed by full-text screening. A third reviewer will resolve any arising conflicts in the process of data screening and inclusion. Subsequently, data extraction and quality assessment using the Critical Appraisal Skills Programme (CASP) tool will be conducted. The results will be analyzed using thematic analysis.
RESULTS: This review is part of a PhD program funded in January 2023. The review commenced in June 2023, and data analysis is currently in progress. The qualitative synthesis will explore the experiences of CRCI across common cancers. The included studies are expected to report on numerous cancer types such as breast cancer, prostate cancer, leukemia, and lung cancer. The included study types are most likely to be interviews, focus groups, and surveys with qualitative components.
CONCLUSIONS: This protocol highlights the need for a qualitative synthesis that will explore the experience of CRCI across common cancer types. It will provide valuable insight into the lived experience of CRCI and the cognitive domains that may be disproportionately affected. There is a growing demand for further management interventions and clinically tested treatments of CRCI and the qualitative exploration of patient experience is crucial for their development. This qualitative synthesis will inform future developments and will contribute to improving QoL after cancer.
UNASSIGNED: DERR1-10.2196/56888.
摘要：
背景：癌症相关认知障碍（CRCI）是癌症患者在治疗过程中常见的，35%的患者在治疗完成后出现认知障碍。记忆受损，注意,执行功能，和信息处理速度的报告最多，通常会对日常功能和生活质量（QoL）产生负面影响。尽管有大量的报道,这种不良副作用在常见癌症类型中的调查不足，缺乏对CRCI经验的洞察力。
目的：本定性综合旨在探索与常见癌症的CRCI经验相关的证据。它还旨在了解CRCI在各种癌症类型中的患病率，认知领域，及其对QoL和功能能力的影响。
方法：对数据库的全面搜索，包括PubMed,美国心理学会PsycINFO,CINAHL,还有Scopus,将进行。共有2名独立审稿人将筛选标题和摘要以供收录，其次是全文筛选。第三名审核人员将解决数据筛选和纳入过程中出现的任何冲突。随后，将使用关键评估技能计划（CASP）工具进行数据提取和质量评估。结果将使用主题分析进行分析。
结果：本评论是2023年1月资助的博士课程的一部分。审查于2023年6月开始，目前正在进行数据分析。定性合成将探索跨常见癌症的CRCI的经验。纳入的研究预计将报告许多癌症类型，如乳腺癌，前列腺癌,白血病,还有肺癌.包含的研究类型最有可能是访谈，焦点小组,和具有定性成分的调查。
结论：该方案强调了定性合成的必要性，该方案将探索跨常见癌症类型的CRCI的经验。它将提供对CRCI的生活经验和可能受到不成比例影响的认知领域的宝贵见解。对CRCI的进一步管理干预和临床试验治疗的需求不断增长，对患者体验的定性探索对其发展至关重要。这种定性合成将为未来的发展提供信息，并有助于改善癌症后的QoL。
■DERR1-10.2196/56888。
目的：本定性综合旨在探索与常见癌症的CRCI经验相关的证据。它还旨在了解CRCI在各种癌症类型中的患病率，认知领域，及其对QoL和功能能力的影响。
方法：对数据库的全面搜索，包括PubMed,美国心理学会PsycINFO,CINAHL,还有Scopus,将进行。共有2名独立审稿人将筛选标题和摘要以供收录，其次是全文筛选。第三名审核人员将解决数据筛选和纳入过程中出现的任何冲突。随后，将使用关键评估技能计划（CASP）工具进行数据提取和质量评估。结果将使用主题分析进行分析。
结果：本评论是2023年1月资助的博士课程的一部分。审查于2023年6月开始，目前正在进行数据分析。定性合成将探索跨常见癌症的CRCI的经验。纳入的研究预计将报告许多癌症类型，如乳腺癌，前列腺癌,白血病,还有肺癌.包含的研究类型最有可能是访谈，焦点小组,和具有定性成分的调查。
结论：该方案强调了定性合成的必要性，该方案将探索跨常见癌症类型的CRCI的经验。它将提供对CRCI的生活经验和可能受到不成比例影响的认知领域的宝贵见解。对CRCI的进一步管理干预和临床试验治疗的需求不断增长，对患者体验的定性探索对其发展至关重要。这种定性合成将为未来的发展提供信息，并有助于改善癌症后的QoL。
■DERR1-10.2196/56888。
