本研究旨在评估锰配合物与赖氨酸和谷氨酸(Mn-LG)作为锰(Mn)来源对生长性能的影响,微量元素沉积,抗氧化能力,断奶仔猪的掌骨强度。该研究涉及288只健康的Duroc×Landrace×Yorkshire仔猪,这些仔猪在25-28日龄断奶,体重为8.66±0.96kg。这些仔猪被随机分为六组:对照组(Mn-LG-0,接受不补充Mn的基础饮食),硫酸锰组(基础日粮补充40mg·kg-1的锰,Mn-S-40基团),和四个Mn-LG组(Mn-LG-20,Mn-LG-40,Mn-LG-60,Mn-LG-80,从Mn中补充20、40、60和80mg·kg-1Mn-LG在基础饮食中)。分组在实验的第0天断奶时开始。在实验的早期(d0-14)和后期(d15-42),以玉米-大豆为基础的基础日粮含有20.88和30.12mg·kg-1Mn,分别。在第14天和第42天收集血液样品,并在第42天处死猪用于样品收集。结果表明,平均日增重没有显着差异,平均日采食量,各组之间的饲料增重比(P>0.05)。所有Mn-LG组和Mn-S-40组的腹泻率在0-14d和整个实验期间均显着低于Mn-LG-0组(P<0.001)。在第42天,Mn-LG-40组肝脏Mn浓度和血清Mn超氧化物歧化酶(Mn-SOD)活性显着增加(P<0.01)。粪便锰浓度显著降低(P<0.05),与Mn-S-40组相比。在血清中检测到显著差异(P<0.05),肝脏,和粪便锰浓度,以及在血清和肝脏中的Mn-SOD活性,不同的Mn-LG组。随着Mn-LG添加量的增加,血清和粪便Mn浓度和血清Mn-SOD活性呈线性或平方增加(P<0.01)。在肾脏中没有发现显着差异(P>0.05)。心,或掌骨Mn浓度或骨强度指数。总之,与Mn-LG-0饮食相比,饲粮添加Mn-LG可提高血清Mn沉积和Mn-SOD活性,降低腹泻的发生率。此外,在相同剂量下,Mn-LG组的粪便Mn浓度低于无机组。
The present study sought to assess the effects of manganese complexes with lysine and glutamic acid (Mn-LG) as manganese (Mn) sources on growth performance, trace element deposition, antioxidant capacity, and metacarpal strength in weaned piglets. The study involved 288 healthy Duroc × Landrace × Yorkshire piglets that were weaned at 25 to 28 d of age and weighed 8.66 ± 0.96 kg. These piglets were randomly divided into six groups: a control group (Mn-LG-0, receiving a basal diet without Mn supplementation), a Mn sulfate group (basal diet supplemented with 40 mg·kg-1 diet of Mn, Mn-S-40 group), and four Mn-LG groups (Mn-LG-20, Mn-LG-40, Mn-LG-60, Mn-LG-80, supplemented with 20, 40, 60, and 80 mg·kg-1 Mn from Mn-LG in the basal diet). Grouping began at weaning on the 0th day of the experiment. The corn-soybean-based basal diet during the early (days 0 to 14) and late (days 15 to 42) phases of the experiment contained 20.88 and 30.12 mg·kg-1 Mn, respectively. Blood samples were collected on days 14 and 42, and pigs were sacrificed for sample collection on day 42. The results indicated no significant differences in average daily gain, average daily feed intake, or feed-to-gain ratio among the groups (P > 0.05). The diarrhea rates of all Mn-LG groups and the Mn-S-40 group were significantly lower in the 0 to 14 d and during the entire experimental period than in the Mn-LG-0 group (P < 0.001). The Mn-LG-40 group exhibited a significant increase in liver Mn concentration and serum Mn superoxide dismutase (Mn-SOD) activity on day 42 (P < 0.01), as well as a significant decrease in fecal Mn concentration (P < 0.05), compared to those of the Mn-S-40 group. Significant differences (P < 0.05) were detected in the serum, liver, and fecal Mn concentrations, as well as in the serum and liver Mn-SOD activity, across the different Mn-LG groups. The serum and fecal Mn concentrations and serum Mn-SOD activity increased linearly or quadratically (P < 0.01) with increasing Mn-LG supplementation. No significant differences (P > 0.05) were found in kidney, heart, or metacarpal bone Mn concentrations or in bone strength indices. In summary, compared with the Mn-LG-0 diet, dietary supplementation with Mn-LG enhanced serum Mn deposition and Mn-SOD activity and decreased the incidence of diarrhea. Additionally, the fecal Mn concentration was lower in the Mn-LG group than in the inorganic group at equivalent dosages.
This research explored the effects of a manganese complex containing lysine and glutamic acid (Mn-LG) on various health parameters in weaned piglets. Utilizing samples of 288 piglets, the study investigated how Mn-LG supplementation influences growth performance, Mn deposition and emission, antioxidant capacity, and metacarpal strength. Key findings include an increase in serum Mn levels and Mn superoxide dismutase (Mn-SOD) activity, a reduction in diarrhea incidence, and no significant effects in bone strength indices in piglets receiving Mn-LG. Additionally, the fecal Mn concentration was notably lower in the Mn-LG group than in the group receiving inorganic Mn at equivalent dosages.