甲壳素,自然界中最普遍的聚合物,一种重要的结构多糖,仅次于纤维素。几丁质是真菌细胞壁的重要组成部分,也存在于许多其他生物中,如病毒,植物,动物,昆虫外骨骼,和甲壳类动物的贝壳.几丁质是生物农药开发的有希望的目标。它专注于解开与甲壳素相关的独特结构和生化途径,旨在确定可在战略上利用的脆弱性,以有效和环境可持续的虫害控制。它涉及对几丁质酶的全面分析,几丁质生物合成,以及跨不同生物体的几丁质相关过程。通过阐明几丁质代谢中涉及的分子复杂性,这篇综述旨在揭示潜在的干预点,这些干预点可以破坏目标害虫的基本生物过程,而不会损害非目标物种。这种了解几丁质相关途径的整体方法旨在为生物农药的设计和优化提供更高的特异性和更低的生态影响。这项研究的结果对推进创新和生态友好的害虫管理策略具有很大的希望。通过靶向几丁质结构和途径,基于这些发现开发的生物农药可能为传统化学农药提供可持续和选择性的替代品,为正在进行的努力做出贡献,以寻求更环保和有效的虫害控制解决方案。
Chitin, the most prevalent polymer in nature, a significant structural polysaccharide that comes in second only to cellulose. Chitin is a crucial component of fungal cell walls and also present in many other creatures, such as viruses, plants, animals, insect exoskeletons, and crustacean shells. Chitin presents itself as a promising target for the development of
biopesticides. It focuses on unraveling the unique structures and biochemical pathways associated with chitin, aiming to identify vulnerabilities that can be strategically leveraged for effective and environmentally sustainable pest control. It involves a comprehensive analysis of chitinase enzymes, chitin biosynthesis, and chitin-related processes across diverse organisms. By elucidating the molecular intricacies involved in chitin metabolism, this review seeks to unveil potential points of intervention that can disrupt essential biological processes in target pests without harming non-target species. This holistic approach to understanding chitin-related pathways aims to inform the design and optimization of
biopesticides with enhanced specificity and reduced ecological impact. The outcomes of this study hold great promise for advancing innovative and eco-friendly pest management strategies. By targeting chitin structures and pathways,
biopesticides developed based on these findings may offer a sustainable and selective alternative to conventional chemical pesticides, contributing to the ongoing efforts towards more environmentally conscious and effective pest control solutions.