Tracheal Stenosis

气管狭窄
  • 文章类型: Journal Article
    目的:评估一种名为Dragonfly的新缝合技术用于闭合临时气管切开术的有效性。该技术涉及在气管切开术过程中放置两条缝线,并使它们松弛且未打结,直到皮肤闭合之日。
    方法:回顾性病例对照研究。意大利三级中心的耳鼻咽喉科和头颈外科的单中心研究。共有50名患者在2017年1月至2021年12月期间接受了临时气管切开术。根据气管闭合方法将患者分为两组:在皮肤闭合过程中放置缝线的传统闭合(A组)和Dragonfly技术(B组)。通过计算机断层扫描(CT)检查气管狭窄的发生率,肉芽组织形成,出血,程序持续时间,对患者的不适感进行了评估。
    结果:与A组(24%)相比,B组(6%)的气管并发症和气管狭窄的发生率降低。手术时间(3分钟vs.6分钟)的持续时间明显较短。手术结束时,没有患者出现气管狭窄的症状。
    结论:Dragonfly缝合技术对于气管切开闭合是有效和安全的,与传统方法相比,降低了气管狭窄的发生率,缩短了住院时间。
    OBJECTIVE: To assess the effectiveness of a new suturing technique called Dragonfly for the closure of temporary tracheotomies. This technique involves placing two sutures during the tracheotomy procedure and leaving them loose and unknotted until the day of skin closure.
    METHODS: Retrospective case control study. Monocentric study at a department of Otolaryngology and head and neck surgery at a tertiary centre in Italy. A total of 50 patients who underwent temporary tracheotomy between January 2017 and December 2021. Patients were divided into two groups based on the trachea closure method: traditional closure with sutures placed during the skin closure procedure (Group A) and the Dragonfly technique (Group B). The incidence of tracheal stenosis by Computed Tomography (CT), granulation tissue formation, bleeding, procedure duration, patient discomfort were evaluated.
    RESULTS: The incidence of tracheal complications and tracheal stenosis was reduced in Group B (6%) compared to Group A (24%). Procedure times (3 min vs. 6 min) durations was significantly shorter. No patients had symptoms of tracheal stenosis at the end of the procedures.
    CONCLUSIONS: The Dragonfly suturing technique is effective and safe for tracheotomy closure, reducing the incidence of tracheal stenosis and shortening hospitalization duration compared to the traditional method.
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  • 文章类型: Case Reports
    方法:一名82岁女性,因声带麻痹和长期糜烂而进行远程气管造口术,血清阳性的类风湿性关节炎(RA)与甲氨蝶呤控制良好,在ED寻求治疗1个月的呼吸困难,胸闷,咳血痰。她作为门诊病人接受了多个疗程的抗生素治疗失败。她没有吸烟或饮酒,最近也没有出国旅行。考虑到气道受损,她被送进了医院。
    METHODS: An 82-year-old woman with a remote tracheostomy due to vocal cord paralysis and long-standing erosive, seropositive rheumatoid arthritis (RA) well controlled with methotrexate sought treatment at the ED with 1 month of dyspnea, chest tightness, and cough productive of blood-tinged sputum. She had been treated unsuccessfully as an outpatient with multiple courses of antibiotics. She did not smoke or drink alcohol and had no recent travel outside the country. Given concern for airway compromise, she was admitted to the hospital.
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  • 文章类型: Journal Article
    对于由结核(TB)引起的严重气管支气管狭窄,通常需要手术重建。然而,这种方法的长期疗效尚不清楚.这项研究调查了手术治疗结核病后严重气管支气管狭窄的安全性和长期结果。
    我们对2015年至2018年在结核病流行地区接受手术重建的48例重度结核病后气管支气管狭窄患者进行了回顾性研究。术前和术后评估包括Karnofsky表现状态,改良医学研究理事会(mMRC)呼吸困难量表,肺活量测定,胸部计算机断层扫描(CT)扫描,和支气管镜检查。主要结果是长期需要干预的再狭窄。
    患者平均年龄为30.6±9.9岁,女性占91.7%。气道纤维化是主要病变(93.8%),影响支气管(93.8%)和气管(6.2%)。所有患者均行切除吻合术,56.2%需要肺叶切除术。术后并发症13例(27.1%),长期漏气是最普遍的(12.5%)。所有并发症均通过保守治疗解决。性能状态的显著改善,呼吸困难,术后观察肺功能,持续5年以上。在69个月的中位随访时间内,在第一年内发生了5例需要干预的再狭窄.从1年开始,再狭窄的发生率为90%。
    手术重建治疗肺结核后严重气管支气管狭窄是安全有效的。需要更大规模的研究来验证这些发现。
    UNASSIGNED: Surgical reconstruction is often necessary for severe tracheobronchial stenosis resulting from tuberculosis (TB). However, the long-term efficacy of this approach remains unclear. This study investigated the safety and long-term outcomes of surgery for severe post-TB tracheobronchial stenosis.
    UNASSIGNED: We conducted a retrospective study of 48 patients with severe post-TB tracheobronchial stenosis who underwent surgical reconstruction between 2015 and 2018 in a TB-endemic region. Pre- and postoperative evaluations included Karnofsky performance status, modified Medical Research Council (mMRC) dyspnea scale, spirometry, chest computed tomography (CT) scan, and bronchoscopy. The primary outcome was intervention-requiring restenosis over the long term.
    UNASSIGNED: The mean patient age was 30.6±9.9 years, with 91.7% females. Airway fibrosis was the predominant lesion (93.8%), affecting the bronchi (93.8%) and trachea (6.2%). All the patients underwent resection and anastomosis, and 56.2% required lobectomy. Postoperative complications occurred in 13 patients (27.1%), with prolonged air leaks being the most prevalent (12.5%). All complications resolved with conservative management. Significant improvements in performance status, dyspnea, and lung function were observed postoperatively and sustained for over 5 years. Within a median follow-up of 69 months, five cases of intervention-requiring restenosis occurred within the first year. The freedom from restenosis rate was 90% from 1 year onwards.
    UNASSIGNED: Surgical reconstruction is safe and effective in treating severe post-TB tracheobronchial stenosis. Larger studies are required to validate these findings.
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  • 文章类型: Journal Article
    鼻巩膜瘤通常被描述为由鼻巩膜克雷伯菌引起的慢性肉芽肿性疾病,主要影响鼻子和鼻咽。当存在时,气管表现将在疾病过程的后期而不是最初的表现。我们描述了一种罕见的非地方性鼻巩膜瘤,以气管病变为疾病的初始表现。
    病例报告和文献复习。
    一名88岁男性出现长期发音困难。柔性喉镜检查显示间隔穿孔和弥漫性声门病变。CT颈部显示非阻塞性息肉样气管病变和鼻旁窦粘膜增厚。活检证实格罗科特亚甲基胺银和斯坦纳染色上的巨噬细胞内非典型淋巴组织细胞增殖和微生物与鼻硬结一致。他被转介接受风湿病学和肺科咨询。
    全身性疾病很少影响气管,甚至更不常见的是气管病变被确定为疾病的最初表现。影响气管的最常见的全身性疾病包括复发性多软骨炎,肉芽肿性多血管炎,淀粉样变性,和炎症性肠病.围绕鼻喉气管鼻硬结瘤的文献有限,尤其是在非流行地区。在鉴别诊断中有必要包括异常的气道病变病因。这需要包括活检在内的全面气道评估。
    4.
    UNASSIGNED: Rhinoscleroma is classically described as a chronic granulomatous disease caused by Klebsiella rhinoscleromatis which primarily affects the nose and nasopharynx. When present, tracheal manifestations will be seen late in the disease course rather than on initial presentation. We describe a rare case of nonendemic rhinoscleroma that presented with tracheal lesions as an initial manifestation of disease.
    UNASSIGNED: Case report and literature review.
    UNASSIGNED: An 88-year-old male presented with longstanding dysphonia. Flexible laryngoscopy demonstrated a septal perforation and diffuse glottic lesions. CT neck demonstrated a nonobstructive polypoid tracheal lesion and mucosal thickening of the paranasal sinuses. Biopsy confirmed an atypical lympho-histiocytic proliferation and microorganisms within macrophages on Grocott methenamine silver and Steiner stains consistent with rhinoscleroma. He was referred for rheumatology and pulmonology consultation.
    UNASSIGNED: Systemic diseases rarely affect the trachea, and even less frequently is a tracheal lesion identified as the initial manifestation of disease. The most common systemic diseases that affect the trachea include relapsing polychondritis, granulomatosis with polyangiitis, amyloidosis, and inflammatory bowel disease. The literature surrounding nasolaryngotracheal rhinoscleroma is limited, especially in nonendemic areas. It is necessary to include unusual etiologies of airway lesions in the differential diagnosis, which warrants comprehensive airway evaluation including biopsy.
    UNASSIGNED: 4.
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  • 文章类型: English Abstract
    Objective:To investigate the therapeutic effect of laryngotracheal rupture injury and management of related complications. Methods:A retrospective analysis was conducted on 10 patients with laryngotracheal rupture injury caused by trauma, admitted between October 2014 and October 2022. Results:Anti-shock treatment, local debridement, tracheal-cricoid cartilage or tracheal-tracheal anastomosis, laryngeal cartilage reduction and fixation, local transposition flaps repair and phase-Ⅱ airway reconstruction were performed respectively on 10 patients. Nine patients underwent operations of tracheal-cricoid cartilage or tracheal-tracheal anastomosis, with five of these were performed by cartilage broken reduction and fixation, placed with intraluminal stents of iodoform gauze fingerstalls for (8.2±1.6) days. Tracheal reconstruction surgery was performed on 2 cases during phase-Ⅱ and both were placed with T-shaped silicone tube to support for 3 months. Two cases required tracheoesophageal fistula surgical repair, and vocal cord suturing was conducted for three vocal fold injuries. Anti-shock treatment was given to one emergency case and closed thoracic drainage treatment was given to another one. We removed the tracheal cannula from 10 patients after surgery and one case was diagnosed with Ⅰ-level swallowing function of sub-water test. All cases recovered to take food per-orally. Conclusion:Maintenance of circulation and respiration functions is the major target during early treatment of laryngotracheal rupture. It should strive to complete the reconstruction of airway structure on phase-Ⅰ, among which end-to-end anastomosis to reconstruct airway and broken laryngeal cartilage reduction and fixation are the vital methods for airway structure reconstruction to achieve good results. It is suggested that the reconstruction of trachea and esophagus structures should be performed simultaneously to patients with tracheoesophageal fistula.
    目的:探讨喉气管断裂伤治疗效果及相关并发症处理。 方法:回顾性分析2014年10月至2022年10月收治的10例外伤导致喉气管断裂患者的治疗情况。 结果:10例患者分别采用抗休克治疗、局部清创、气管-环状软骨或气管-气管吻合以及喉部软骨复位固定、局部组织瓣修复、Ⅱ期气道重建等治疗。9例患者Ⅰ期行气管-环状软骨或气管-气管吻合手术,其中5例患者行喉软骨骨折固定复位、放置碘仿纱条指套内支撑,放置时间(8.2±1.6) d;2例患者Ⅱ期行气管重建手术,均放置T形硅胶管内支撑3个月。2例行气管食管瘘修复手术;3例声带损伤者行声带缝合术;1例患者急诊进行抗休克治疗,1例患者行胸腔闭式引流治疗。10例患者术后均拔除气管套管,1例患者洼田饮水试验吞咽功能Ⅰ级,全部患者恢复经口进食。 结论:喉气管断裂早期治疗主要维持循环和呼吸功能;喉气管断裂治疗应该争取Ⅰ期重建完整气道结构,其中端端吻合重建气道以及喉部软骨骨折复位固定是气道结构重建取得良好效果的重要手段;对于合并气管食管瘘的患者,建议同期进行气管和食管结构重建。.
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  • 文章类型: Journal Article
    背景:良性气管狭窄相对罕见,但由于其剧烈症状包括呼吸困难和吸气性喘鸣,仍然是一种严重的慢性疾病,以及随之而来的对生活质量的负面影响。传统上,通过切除狭窄的气管段的手术方法一直是首选的治疗方法。然而,内镜技术已经出现,可能提供一种安全且侵入性较小的替代方法。
    目的:回顾性研究的目的是评估单中心良性气管狭窄内镜治疗的手术相关安全性和结果。
    方法:该研究包括2013年至2022年在我院接受硬质气管镜下良性气管狭窄内镜治疗的所有患者,通过电乳头切开针和扩张(内窥镜气管成形术)进行放射状切口,然后进行曲安奈德作为局部粘膜下注射,另外,从2020年开始,布地奈德吸入。
    结果:在总共38项干预措施中,共有22例患者接受了治疗,每个都导致症状的立即改善。无介入围手术期并发症或死亡率。在38项干预措施中,11没有接受曲安奈德给药,平均21.1(±18.0)个月后复发率为54.5%,而27人局部服用曲安奈德,有37%的复发率。自2020年以来,我们还对新入院患者和复发患者(n=8)进行了干预后布地奈德吸入治疗,以预防复发。到目前为止,其中只有一人(12.5%)经历过复发。
    结论:我们的研究结果表明,内镜下气管成形术提供了一种安全、成功、良性气管狭窄患者的微创手术替代开放手术。我们建议将曲安奈德局部用于粘膜作为一种额外的治疗方法,以降低复发的风险。然而,鉴于不受控制的研究设计和低样本量,安全性和有效性无法最终证明。尽管如此,我们的研究结果为进一步调查提供了有希望的途径.需要进一步研究吸入糖皮质激素的额外益处。
    BACKGROUND: Benign tracheal stenosis is relatively rare but remains a significant chronic disease due to its drastic symptoms including dyspnoea and inspiratory stridor, and consequent negative effect on quality of life. Traditionally, the surgical approach by resection of the stenotic tracheal segment has been the therapy of choice. However, endoscopic techniques have arisen and may offer a safe and less invasive alternative.
    OBJECTIVE: The aim of the retrospective study was to evaluate procedure-related safety and outcome of endoscopic treatment of benign tracheal stenosis at a single centre.
    METHODS: The study included all patients at our institution who between 2013 and 2022 had received endoscopic treatment of benign tracheal stenosis by rigid tracheoscopy, radial incision by electric papillotomy needle and dilation (endoscopic tracheoplasty) followed by triamcinolone acetonide as a local submucosal injection and additionally, from 2020, budesonide inhalation.
    RESULTS: A total of 22 patients were treated in a total of 38 interventions, each resulting in immediate improvement of symptoms. There were no peri-interventional complications or mortality. Of the 38 interventions, 11 received no triamcinolone acetonide administration, resulting in a 54.5% recurrence rate after an average of 21.1 (±18.0) months, while 27 had local triamcinolone acetonide, with a 37% recurrence rate. Since 2020, we additionally initiated post-interventional budesonide inhalation as recurrence prophylaxis for newly admitted patients and patients with recurrences(n = 8), of whom only one (12.5%) has to date experienced a recurrence.
    CONCLUSIONS: Our results indicate that endoscopic tracheoplasty offers a safe and successful, minimally invasive alternative to open surgery for patients with benign tracheal stenosis. We recommend local administration of triamcinolone into the mucosa as an additional treatment to decrease the risk of recurrence. However, given the uncontrolled study design and low sample size, safety and effectiveness cannot be conclusively demonstrated. Nonetheless, our findings suggest promising avenues for further investigation. Further studies on the additional benefit of inhaled corticosteroids are warranted.
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  • 文章类型: Case Reports
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  • 文章类型: Journal Article
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  • 文章类型: Letter
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  • 文章类型: Case Reports
    T管和气道支架是常用的,但效果有限,并发症频繁。一名50岁的男性患者出现严重的气管狭窄,影响8.7厘米长的气道。我们采用了一种创新的方法,即使用机器人辅助对气管支架进行外部悬挂固定。该方法涉及通过手术将支架附接到气管的外部,以提供支撑并稳定软化或塌陷的气管段。我们设计了C形镍钛合金外部支架,并使用机器人辅助成功地将其固定。这种干预有效地恢复了气管功能,并导致了良好的术后恢复。该技术不影响气管膜功能或气道粘膜纤毛清除。它可能被认为是治疗长段良性气管软化或塌陷的新选择。
    T-tubes and airway stents are commonly used but have limited effectiveness and frequent complications. A 50-year-old male patient presented with severe tracheal stenosis, affecting an 8.7 cm length of the airway. We employed an innovative approach known as external suspension fixation of tracheal stent using robotic assistance. This method involves surgically attaching the stent to the exterior of the trachea to provide support and stabilize the softened or collapsed tracheal segments. We designed a C-shaped nickel-titanium alloy exterior stent and successfully fixed it using robotic assistance. This intervention effectively restored tracheal function and led to a favorable postoperative recovery. The technique does not affect tracheal membrane function or airway mucociliary clearance. It could potentially be considered as a new option for treating long-segment benign tracheal softening or collapse.
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