PDF(Pubmed)
Abstract：
UNASSIGNED: Rhinoscleroma is classically described as a chronic granulomatous disease caused by Klebsiella rhinoscleromatis which primarily affects the nose and nasopharynx. When present, tracheal manifestations will be seen late in the disease course rather than on initial presentation. We describe a rare case of nonendemic rhinoscleroma that presented with tracheal lesions as an initial manifestation of disease.
UNASSIGNED: Case report and literature review.
UNASSIGNED: An 88-year-old male presented with longstanding dysphonia. Flexible laryngoscopy demonstrated a septal perforation and diffuse glottic lesions. CT neck demonstrated a nonobstructive polypoid tracheal lesion and mucosal thickening of the paranasal sinuses. Biopsy confirmed an atypical lympho-histiocytic proliferation and microorganisms within macrophages on Grocott methenamine silver and Steiner stains consistent with rhinoscleroma. He was referred for rheumatology and pulmonology consultation.
UNASSIGNED: Systemic diseases rarely affect the trachea, and even less frequently is a tracheal lesion identified as the initial manifestation of disease. The most common systemic diseases that affect the trachea include relapsing polychondritis, granulomatosis with polyangiitis, amyloidosis, and inflammatory bowel disease. The literature surrounding nasolaryngotracheal rhinoscleroma is limited, especially in nonendemic areas. It is necessary to include unusual etiologies of airway lesions in the differential diagnosis, which warrants comprehensive airway evaluation including biopsy.
UNASSIGNED: 4.
UNASSIGNED: Case report and literature review.
UNASSIGNED: An 88-year-old male presented with longstanding dysphonia. Flexible laryngoscopy demonstrated a septal perforation and diffuse glottic lesions. CT neck demonstrated a nonobstructive polypoid tracheal lesion and mucosal thickening of the paranasal sinuses. Biopsy confirmed an atypical lympho-histiocytic proliferation and microorganisms within macrophages on Grocott methenamine silver and Steiner stains consistent with rhinoscleroma. He was referred for rheumatology and pulmonology consultation.
UNASSIGNED: Systemic diseases rarely affect the trachea, and even less frequently is a tracheal lesion identified as the initial manifestation of disease. The most common systemic diseases that affect the trachea include relapsing polychondritis, granulomatosis with polyangiitis, amyloidosis, and inflammatory bowel disease. The literature surrounding nasolaryngotracheal rhinoscleroma is limited, especially in nonendemic areas. It is necessary to include unusual etiologies of airway lesions in the differential diagnosis, which warrants comprehensive airway evaluation including biopsy.
UNASSIGNED: 4.
摘要：
■鼻巩膜瘤通常被描述为由鼻巩膜克雷伯菌引起的慢性肉芽肿性疾病，主要影响鼻子和鼻咽。当存在时,气管表现将在疾病过程的后期而不是最初的表现。我们描述了一种罕见的非地方性鼻巩膜瘤，以气管病变为疾病的初始表现。
■病例报告和文献复习。
■一名88岁男性出现长期发音困难。柔性喉镜检查显示间隔穿孔和弥漫性声门病变。CT颈部显示非阻塞性息肉样气管病变和鼻旁窦粘膜增厚。活检证实格罗科特亚甲基胺银和斯坦纳染色上的巨噬细胞内非典型淋巴组织细胞增殖和微生物与鼻硬结一致。他被转介接受风湿病学和肺科咨询。
■全身性疾病很少影响气管，甚至更不常见的是气管病变被确定为疾病的最初表现。影响气管的最常见的全身性疾病包括复发性多软骨炎，肉芽肿性多血管炎，淀粉样变性,和炎症性肠病.围绕鼻喉气管鼻硬结瘤的文献有限，尤其是在非流行地区。在鉴别诊断中有必要包括异常的气道病变病因。这需要包括活检在内的全面气道评估。
■4.
■病例报告和文献复习。
■一名88岁男性出现长期发音困难。柔性喉镜检查显示间隔穿孔和弥漫性声门病变。CT颈部显示非阻塞性息肉样气管病变和鼻旁窦粘膜增厚。活检证实格罗科特亚甲基胺银和斯坦纳染色上的巨噬细胞内非典型淋巴组织细胞增殖和微生物与鼻硬结一致。他被转介接受风湿病学和肺科咨询。
■全身性疾病很少影响气管，甚至更不常见的是气管病变被确定为疾病的最初表现。影响气管的最常见的全身性疾病包括复发性多软骨炎，肉芽肿性多血管炎，淀粉样变性,和炎症性肠病.围绕鼻喉气管鼻硬结瘤的文献有限，尤其是在非流行地区。在鉴别诊断中有必要包括异常的气道病变病因。这需要包括活检在内的全面气道评估。
■4.
