桔梗(P.grandiflorus),一种既用于医药又用于食品的传统中草药,有治疗呼吸道感染的悠久历史,支气管炎,肺炎,和其他肺部相关疾病。的治疗效果是由于其化学成分,包括多糖。在这些组件中,桔梗多糖(PGP)是公认的最重要和最丰富的活性成分之一,表现出各种生物活性,如益生元,抗氧化剂,抗病毒,抗癌,抗血管生成,和免疫调节特性。结合中医原理,承运人概念,和现代靶向药物递送技术,PGP可以影响其他药物的靶位点和治疗效果,同时也可以作为靶向和精确治疗的药物载体。因此,必须对提取进行全面审查,分离,净化,物理化学性质,PGP的生物学活性。在未来,通过整合新概念,技术,和过程,可为PGP的全面发展提供参考和指导。这将有助于P.grandiflorus在各个领域的进步,如制药,健康产品,和食物。
Platycodon grandiflorus (P. grandiflorus), a traditional Chinese medicinal herb used for both medicine and food, has a long history of treating respiratory infections, bronchitis, pneumonia, and other lung-related diseases. The therapeutic effects of P. grandiflorus are attributed to its chemical components, including polysaccharides. Among these components, Platycodon grandiflorus polysaccharides (PGP) are recognized as one of the most important and abundant active ingredients, exhibiting various biological activities such as prebiotic, antioxidant, antiviral, anticancer, antiangiogenic, and immune regulatory properties. Incorporating the principles of traditional Chinese medicine, carrier concepts, and modern targeted drug delivery technologies, PGP can influence the target sites and therapeutic effects of other drugs while also serving as a drug carrier for targeted and precise treatments. Therefore, it is essential to provide a comprehensive review of the extraction, separation, purification, physicochemical properties, and biological activities of PGP. In the future, by integrating new concepts, technologies, and processes, further references and guidance can be provided for the comprehensive development of PGP. This will contribute to the advancement of P. grandiflorus in various fields such as pharmaceuticals, health products, and food.