Skin of color

肤色
  • 文章类型: Case Reports
    Follicocystic和胶原蛋白错构瘤(FCCH)是一种罕见的实体,通常记录在男性结节性硬化症。这里,我们报告了一例19岁女性FCCH的独特病例,外生殖器异常。患者在三年内表现出逐渐扩大的肿块,造成行走和坐着的困难。检查显示10x15厘米的嫩芽,分叶状,皮肤颜色的肿瘤,有来自右唇的粉刺样开口,两个大阴唇上都有卫星病变.她没有其他症状或病史提示结节性硬化症。组织病理学检查显示有角蛋白的毛囊扩张,卵泡周纤维化,和延伸到皮下组织的厚真皮胶原蛋白带,确认FCCH。该病例强调了在生殖器肿块的鉴别诊断中考虑FCCH的重要性,即使没有经典的临床关联。我们的发现有助于有关FCCH的有限文献,并强调了医学界进一步探索和认识的必要性。
    Folliculocystic and collagen hamartoma (FCCH) is a rare entity, typically documented in males with tuberous sclerosis complex. Here, we report a unique case of FCCH in a 19-year-old female with an unusual presentation in the external genitalia. The patient presented with a progressively enlarging mass over three years, causing difficulties in walking and sitting. Examination revealed a 10 x 15 cm tender, lobulated, skin-colored tumor with comedo-like openings originating from the right labium majus, with satellite lesions on both labia majora. She had no other symptoms or history suggestive of tuberous sclerosis. Histopathological examination showed dilated hair follicles with keratin, perifollicular fibrosis, and thick dermal collagen bands extending into subcutaneous tissue, confirming FCCH. This case underscores the importance of considering FCCH in the differential diagnosis of genital masses, even without classical clinical associations. Our findings contribute to the limited literature on FCCH and highlight the need for further exploration and awareness within the medical community.
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  • 文章类型: Journal Article
    描述特应性皮炎是一种慢性炎症性皮肤病,通常会影响身体的弯曲区域。它存在于儿童和成人中,包括那些皮肤色素沉着较深的人。慢性病变是干燥的色素沉着斑块,破裂,和/或经常伴有苔藓化的鳞状。鉴别诊断包括牛皮癣,脂溢性皮炎,鱼鳞病,和玫瑰糠疹.本文将根据Fitzpatrick量表展示各种年龄组和肤色的慢性特应性皮炎的临床图像。
    Description Atopic dermatitis is a chronic inflammatory skin disorder classically affecting flexural areas of the body. It is present in children and adults, including those with darker skin pigmentation. Chronic lesions are hyperpigmented plaques that are dry, cracked, and/or scaly often with lichenification. Differential diagnoses include psoriasis, seborrheic dermatitis, ichthyosis, and pityriasis rosea. This article will showcase clinical images with varying presentations of chronic atopic dermatitis in a range of age groups and skin colors according to the Fitzpatrick scale.
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  • 文章类型: Journal Article
    描述角化病于1893年首次被描述。这是一种相对罕见的疾病,有9种以上的亚型。病变的临床特征是界限分明的,红斑丘疹(凸起,<1厘米)或斑块(凸起,>1厘米),有一个萎缩的中心,和凸起的鳞状边界。角化病是一种重要的诊断,因为它可能会发生恶性转化并模仿许多常见的诊断。这些通常模拟的诊断包括鳞状细胞癌,体癣,钱币状皮炎,和寻常型牛皮癣,仅举几例。这篇综述中的临床图像集中在识别整个肤色范围内的孔角化病。
    Description Porokeratosis was first described in 1893. It is a relatively rare disorder with over 9 subtypes. Lesions are clinically characterized as well-demarcated, erythematous papules (raised, <1 cm) or plaques (raised, >1 cm), with an atrophic center, and raised scaly border. Porokeratosis is an important diagnosis to identify because it may undergo malignant transformation and mimics many commonly encountered diagnoses. These commonly mimicked diagnoses include squamous cell carcinoma, tinea corporis, nummular dermatitis, and psoriasis vulgaris, to name a few. The clinical images in this review focus on identifying porokeratosis along the full spectrum of skin tones.
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  • 文章类型: Journal Article
    描述脂溢性皮炎是一种常见的皮肤病,影响所有年龄段的患者,种族,和皮肤色素沉着。皮疹经常影响头皮,耳朵,中央的脸。个体的潜在皮肤色素沉着可能会影响这种疾病的表现。我们介绍了不同年龄个体的脂溢性皮炎的几例,性别,和皮肤色素沉着。
    Description Seborrheic dermatitis is a common dermatologic disease affecting patients of all ages, ethnicities, and skin pigmentations. The rash often affects the scalp, ears, and central face. The underlying skin pigmentation of the individual may affect how this disease presents. We present several cases of seborrheic dermatitis in individuals of varying ages, genders, and skin pigmentations.
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  • 文章类型: Letter
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  • 文章类型: Letter
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  • 文章类型: Systematic Review
    目的:为了确定皮肤颜色在涉及基底细胞癌(BCC)鉴定和治疗的随机对照试验(RCT)中的报道率,在十大皮肤病学杂志上。
    方法:对十大皮肤病学期刊中涉及BCC的RCT进行了系统评价,由影响因子决定,从成立到7月11日,2023年。如果他们审查了预防措施,检测,和BCC的治疗,直接参与的患者,并被分类为随机对照试验。如果方法或结果中的人口统计学数据包括以下任何一项,则将报告肤色(SOC)的研究分类为阳性:Fitzpatrick量表,种族,种族,肤色,或晒伤倾向。
    结果:在确定的51项研究中,只有23篇文章在结果部分报告了与肤色有关的数据(45.1%);而28篇文章在文本中提到了肤色(54.9%).进行亚组分析,研究地点或发表年份无统计学意义.
    结论:皮肤暗色会使诊断皮肤肿瘤变得更加困难,种族是否会影响对治疗的反应尚不清楚。在国际顶级皮肤病学期刊中,与基底细胞癌相关的RCT中,少于50%的人在其结果部分与研究参与者有关的人口统计学部分中包括肤色。亚组分析表明,在美国进行的研究报告皮肤颜色少于一半的时间(40%)。此外,在过去的40年中,报告没有统计学上的显著差异.需要进一步的研究来确定与BCC相关的RCTS中种族/肤色的低报告率是否会影响该组患者护理的诊断或治疗建议。
    OBJECTIVE: To determine the rate skin color is reported in randomized controlled trials (RCTs) involving basal cell carcinoma (BCC) identification and treatment in the top ten dermatology journals.
    METHODS: A systematic review was conducted of RCTs involving BCC among the top ten dermatology journals, determined by impact factor, from inception to July 11th, 2023. Studies were included if they reviewed the prevention, detection, and treatment of BCC, directly involved patients, and were classified as RCTs. Studies were classified as positive for reporting skin of color (SOC) if the demographic data in the methods or results included any of the following terms: Fitzpatrick scale, race, ethnicity, skin of color, or sunburn tendency.
    RESULTS: Of the 51 studies identified, only 23 articles reported data pertaining to skin color within the results section (45.1%); whereas 28 articles mentioned skin color somewhere within the text (54.9%). Subgroup analysis was performed, and no statistical significance was found for study location or year of publication.
    CONCLUSIONS: Dark skin color can make it more difficult to diagnose skin tumors and it is unknown if race affects response to treatment. Less than 50% of RCTs related to basal cell carcinoma in top international dermatology journals included skin color within the demographic portion of their results section pertaining to study participants. Subgroup analysis demonstrated that studies performed within the United States reported skin color less than half the time (40%). Additionally, there has been no statistically significant difference in reporting over the past 4 decades. Further research is necessary to determine whether low reporting rates of race/skin color in BCC-related RCTS could impact diagnostic or treatment recommendations for patient care in this group.
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  • 文章类型: Case Reports
    大疱性类天疱疮(BP)是一种自身免疫性皮肤病,会导致充满液体的水疱出现在身体各个部位,通常在荨麻疹和瘙痒之前。此病例报告描述了患有BP的有色患者皮肤患病区域内的毛囊周围黑素细胞再生。通过回顾可能导致黑素细胞破坏的各种病理和黑素细胞再生的基础科学,我们可以更好地识别并向患者解释这种现象,并导致早期诊断。此外,由于缺乏有关彩色患者皮肤状况的公开信息,本报告有助于提高人们对皮肤病社区非典型BP表现的认识.
    Bullous pemphigoid (BP) is an autoimmune skin disorder that causes fluid-filled blisters to appear on various body parts, often preceded by urticaria and pruritis. This case report describes the perifollicular melanocyte regeneration within diseased areas in a skin of color patient with BP. By reviewing the various pathologies that can result in melanocyte destruction and the basic science of melanocyte regeneration, we can better identify and explain this phenomenon to patients and lead to earlier diagnoses. Furthermore, due to the lack of published information on skin conditions in skin of color patients, this report can assist in raising awareness of an atypical BP presentation in the dermatological community.
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  • 文章类型: Journal Article
    少数民族经历的健康不平等一直是一个持续的全球现象。诊断不同类型的皮肤状况,例如,黑色素瘤,有色人种是可能发生误诊的健康领域之一,可能导致危及生命的后果。尽管高加索人更有可能被诊断为黑色素瘤,由于延迟诊断,非洲裔美国人出现IV期黑色素瘤的可能性要高出四倍。必须认识到,社会经济地位和获得医疗保健服务的机会有限等其他因素可能是促成因素。非洲裔美国人死于黑色素瘤的可能性也是白种人的1.5倍,非洲裔美国人的5年生存率明显低于高加索人(72.2%vs.89.6%)。这是一个复杂的问题,加上几个因素:准备不足的医生,有色人种缺乏对黑色素瘤和其他皮肤病的认识,缺乏信息和医疗资源,为从业者的不断发展,有色人种在研究中代表性不足,POC是一个出了名的难以接触的群体,和“粉刷的”医学院课程。虽然数字技术可以为减少健康不平等带来新的希望,人工智能在医疗保健中的部署会带来风险,可能会放大有色人种所经历的健康差距,而数字技术可能会提供一种虚假的参与感。例如,真皮辅助,正在开发的皮肤诊断电话应用程序,已经因为依赖少数有色人种的数据而受到批评。本文着重了解有色人种皮肤状况的误诊问题,并探索已尝试的进展和创新,为大数据分析的可能应用铺平道路,人工智能,和以用户为中心的技术,以减少有色人种之间的健康不平等。
    The health inequalities experienced by ethnic minorities have been a persistent and global phenomenon. The diagnosis of different types of skin conditions, e.g., melanoma, among people of color is one of such health domains where misdiagnosis can take place, potentially leading to life-threatening consequences. Although Caucasians are more likely to be diagnosed with melanoma, African Americans are four times more likely to present stage IV melanoma due to delayed diagnosis. It is essential to recognize that additional factors such as socioeconomic status and limited access to healthcare services can be contributing factors. African Americans are also 1.5 times more likely to die from melanoma than Caucasians, with 5-year survival rates for African Americans significantly lower than for Caucasians (72.2% vs. 89.6%). This is a complex problem compounded by several factors: ill-prepared medical practitioners, lack of awareness of melanoma and other skin conditions among people of colour, lack of information and medical resources for practitioners\' continuous development, under-representation of people of colour in research, POC being a notoriously hard to reach group, and \'whitewashed\' medical school curricula. Whilst digital technology can bring new hope for the reduction of health inequality, the deployment of artificial intelligence in healthcare carries risks that may amplify the health disparities experienced by people of color, whilst digital technology may provide a false sense of participation. For instance, Derm Assist, a skin diagnosis phone application which is under development, has already been criticized for relying on data from a limited number of people of color. This paper focuses on understanding the problem of misdiagnosing skin conditions in people of color and exploring the progress and innovations that have been experimented with, to pave the way to the possible application of big data analytics, artificial intelligence, and user-centred technology to reduce health inequalities among people of color.
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  • 文章类型: Journal Article
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