Shocks

冲击
  • 文章类型: Journal Article
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  • 文章类型: Journal Article
    最近,据报道,植入式心脏复律除颤器中的极性依赖性电击失败是由高压馈通的结构故障引起的。当右心室线圈在双相电击(阴极电击)的1阶段处于阴极状态时,可能会发生短路。这种观点提出了一种观察到的极性依赖性的机制,并考虑了相同的机制是否可能适用于其他冲击引起的,短路。植入式心律转复除颤器与导线的连接穿过馈通进入密封外壳(“Can”)。馈通包括2个同心,导电金属圆筒,右心室线圈和外部Can的内部引脚导体,由不透水的绝缘隔开。冲击失效取决于3个条件:1)馈通中流体层的发展,创建与冲击路径平行的传导路径;2)流体中电场的径向梯度,因此,冲击过程中的电阻加热使水蒸发,在引脚周围形成高电阻气泡;3)阴极处电子的场发射,速率和能量取决于场的强度和阴极的势能势垒发射。对于阴极冲击,在金属引脚处发射的电子可能会在气体中引发电离雪崩,直到它“分解”为低电阻等离子体,导致短路。对于阳极电击,有效的阴极是液-气界面,其中磁场比引脚处弱。此外,水溶液中的溶剂化电子必须克服更高的势能势垒才能发射。这允许高阻力气泡稳定,从而完成冲击。
    Recently, polarity-dependent shock failures were reported in implantable cardioverter-defibrillators caused by structural failure in the high-voltage feedthrough. Short circuits may occur when the right ventricular coil is cathodal for phase 1 of biphasic shocks (cathodal shock). This viewpoint proposes a mechanism for observed polarity dependence and considers whether the same mechanism may apply in other shock-induced, short circuits. Implantable cardioverter-defibrillator connections to the lead traverse feedthroughs into the hermetically sealed housing (\"Can\"). The feedthrough comprises 2 concentric, conducting metal cylinders, the inner pin-conductor to the right ventricular coil and outer Can, separated by impermeable insulation. Shock failure depends on 3 conditions: 1) development of a fluid layer in the feedthrough, creating a conduction path in parallel with the shock pathway; 2) the radial gradient of the electric field in the fluid, so resistive heating during a shock vaporizes water to form a high-resistance gas bubble around the pin; and 3) field emission of electrons at the cathode, with rate and energy dependent on the field\'s strength and the cathode\'s potential-energy barrier to emission. For cathodal shocks, electrons emitted at the metal pin may initiate an ionization avalanche in the gas until it \"breaks down\" into a low-resistance plasma, resulting in a short circuit. For anodal shocks, the effective cathode is the liquid-gas interface, where the field is weaker than at the pin. Additionally, solvated electrons in aqueous solution must overcome a higher potential-energy barrier to be emitted. This permits the high-resistance gas bubble to stabilize so that the shock is completed.
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  • 文章类型: Journal Article
    在干扰下保持弹性,同时也是可持续的,在不断变化的世界中,对于持续和公平的海鲜供应至关重要。然而,尽管韧性思想广泛应用于可持续性研究和社会生态可持续性的多个维度,很难确定如何使供应链既具有弹性又可持续。在这次审查中,我们利用社会生态复原力和可持续性文献来确定联系,并强调管理和监测适应性和公平海产品供应链的概念。然后,我们回顾了记录的海鲜供应网络对中断的反应,并详细介绍了一个案例研究,以描述有弹性的海鲜供应系统的属性。最后,我们概述了这些应对措施对社会(包括福祉和公平)的影响,经济和环境可持续性。供应链中断根据其发生频率进行分类(偶发性,慢性,累积)和基本主题来自每种类型的中断的供应链响应。我们发现,海鲜供应链在多样化时具有弹性(在这两种产品中,市场,消费者或加工),已连接,得到各级政府的支持,供应链参与者能够通过基于信任的关系进行学习和协作。有了规划,基础设施和系统制图,这些属性还可以帮助建立社会生态可持续性,并朝着更具适应性和公平的海产品供应迈进。
    Remaining resilient under disruption, while also being sustainable, is essential for continued and equitable seafood supply in a changing world. However, despite the wide application of resilience thinking to sustainability research and the multiple dimensions of social-ecological sustainability, it can be difficult to ascertain how to make a supply chain both resilient and sustainable. In this review, we draw upon the socio-ecological resilience and sustainability literature to identify links and highlight concepts for managing and monitoring adaptive and equitable seafood supply chains. We then review documented responses of seafood supply networks to disruption and detail a case study to describe the attributes of a resilient seafood supply system. Finally, we outline the implications of these responses for social (including wellbeing and equity), economic and environmental sustainability. Disruptions to supply chains were categorised based on their frequency of occurrence (episodic, chronic, cumulative) and underlying themes were derived from supply chain responses for each type of disruption. We found that seafood supply chains were resilient when they were diverse (in either products, markets, consumers or processing), connected, supported by governments at all scales, and where supply chain actors were able to learn and collaborate through trust-based relationships. With planning, infrastructure and systematic mapping, these attributes also can help to build socio-ecological sustainability and move towards more adaptive and equitable seafood supply.
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  • 文章类型: Meta-Analysis
    目的:植入式心律转复除颤器(ICD)预防心源性猝死。焦虑,抑郁症,创伤后应激障碍(PTSD)是未被重视的症状。我们旨在系统地综合情绪障碍和症状严重程度的患病率估计,ICD插入前和后。与对照组进行比较,以及ICD患者的适应症(原发性与secondary),性别,休克状态,随着时间的推移。
    方法:数据库(Medline,PsycINFO,PubMed,和Embase)从开始到2022年8月31日不受限制地搜索;确定了4661篇文章,109例(39954例患者)符合标准。
    结果:随机效应荟萃分析显示,在插入后的所有时间点中,有22.58%(95CI18.26-26.91%)的ICD患者的临床相关焦虑和15.42%(95CI11.90-18.94%)的抑郁。创伤后应激障碍发生率为12.43%(95CI6.90-17.96%)。比率相对于适应症组没有变化。临床相关的焦虑和抑郁在经历电击的ICD患者中更可能[焦虑比值比(OR)=3.92(95CI1.67-9.19);抑郁OR=1.87(95CI1.34-2.59)]。插入后女性的焦虑症状高于男性[Hedges\'g=0.39(95CI0.15-0.62)]。插入后的前5个月抑郁症状减轻[Hedges\'g=0.13(95CI0.03-0.23)],6个月后焦虑症状减轻[Hedges\'g=0.07(95CI0-0.14)]。
    结论:抑郁和焦虑在ICD患者中非常普遍,尤其是那些经历冲击的人。特别值得关注的是ICD植入后PTSD的患病率。心理评估,监测,作为常规护理的一部分,应向ICD患者及其伴侣提供治疗.
    Implantable cardioverter defibrillators (ICDs) prevent sudden cardiac death. Anxiety, depression, and post-traumatic stress disorder (PTSD) are underappreciated symptoms. We aimed to systematically synthesize prevalence estimates of mood disorders and symptom severities, pre- and post-ICD insertions. Comparisons were made with control groups, as well as within ICD patients by indication (primary vs. secondary), sex, shock status, and over time.
    Databases (Medline, PsycINFO, PubMed, and Embase) were searched without limits from inception to 31 August 2022; 4661 articles were identified, 109 (39 954 patients) of which met criteria.
    Random-effects meta-analyses revealed clinically relevant anxiety in 22.58% (95%CI 18.26-26.91%) of ICD patients across all timepoints following insertion and depression in 15.42% (95%CI 11.90-18.94%). Post-traumatic stress disorder was seen in 12.43% (95%CI 6.90-17.96%). Rates did not vary relative to indication group. Clinically relevant anxiety and depression were more likely in ICD patients who experienced shocks [anxiety odds ratio (OR) = 3.92 (95%CI 1.67-9.19); depression OR = 1.87 (95%CI 1.34-2.59)]. Higher symptoms of anxiety were seen in females than males post-insertion [Hedges\' g = 0.39 (95%CI 0.15-0.62)]. Depression symptoms decreased in the first 5 months post-insertion [Hedges\' g = 0.13 (95%CI 0.03-0.23)] and anxiety symptoms after 6 months [Hedges\' g = 0.07 (95%CI 0-0.14)].
    Depression and anxiety are highly prevalent in ICD patients, especially in those who experience shocks. Of particular concern is the prevalence of PTSD following ICD implantation. Psychological assessment, monitoring, and therapy should be offered to ICD patients and their partners as part of routine care.
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  • 文章类型: Journal Article
    旨在遏制COVID-19大流行蔓延的政策措施对全球经济活动产生了意想不到的后果。在这项研究中,我们分离并调查了六项此类措施对农业家庭的农场和非农业收入的短期部分影响,并检查了相关的弹性因素。以尼日利亚为例,我们发现,在短期内,COVID控制措施对农场和非农场收入的影响是混合的。这些不同的影响是由于家庭的复原力和脆弱性因素,包括土地面积,财富,收入多样化,参与加工活动,依赖雇佣劳动力。我们的发现强调了更有针对性的健康危机控制措施的必要性,这些措施考虑了独特性,多样性,和农业的区域异质性,尤其是对农场生存能力的潜在影响。
    Policy measures aimed at containing the spread of the COVID-19 pandemic had unintended consequences on economic activities globally. In this study, we isolate and investigate the short-term partial impacts of six such measures on the farm and nonfarm incomes of agricultural households and examine the related resilience factors. Using Nigeria as a case study, we find that the COVID containment measures had mixed effects on farm and non-farm incomes in the short run. These varying effects are due to households\' resilience and vulnerability factors, including land size, wealth, income diversification, involvement in processing activities, and reliance on hired labor. Our findings highlight the need for more targeted health crisis containment measures which consider the uniqueness, diversity, and regional heterogeneity of agriculture, especially the potential implications for farm viability.
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  • 文章类型: Journal Article
    职业生涯早期阶段是身份维持和改变的关键时期。但是,它也是成熟的重要,注意力抓住事件(即,关键事件)可能会修改这些过程,尤其影响女性的领导追求。因为以前的研究忽视了这些事件是否或如何改变身份,或者这些过程是否对男性和女性不同,我们整合了身份和关键事件文献,以详细说明随着时间的推移,积极和消极的关键事件如何影响男性和女性在工作和非工作领域的身份。我们建议,关键事件对身份显著性的影响将在域内和跨域发生,但这些影响在内部会更强(与跨)域。虽然正面和负面事件都可以对随后的身份显著性产生负面影响,我们认为,关键事件对身份显着性的影响对女性来说可能会更强(与men).最后,我们将工作身份显着性与随后的领导地位联系起来,包括增强或破坏这些影响的上下文主持人(即,包容性的组织氛围和巨大的威胁,分别)。我们总结了这项研究的理论和实践意义,包括劳动力效率和社会可持续性。我们还强调了来自我们评论的未来研究的呼吁[例如,可持续发展的关键事件和性别分析(更多)准确的科学]以及富有成效的研究领域和创新实践在工作-非工作界面的专业人士在领导的道路上。
    The early career phase is a key period of identity maintenance and change. But, it is also ripe with important, attention-grabbing occurrences (i.e., critical events) that may modify these processes, particularly influencing women\'s leadership pursuit. Because previous research has overlooked if or how such events might alter identifying or if these processes differ for people who identify as men and women, we integrate the identity and critical events literatures to elaborate on how positive and negative critical events may shape men and women\'s identifying in the work- and non-work domains over time. We propose that critical events\' effects on identity salience will occur both within and across domains, but that these effects will be stronger within (vs. across) domains. While both positive and negative events can exert negative effects on subsequent identity salience, we propose that the effects of critical events on identity salience may be stronger for women (vs. men). Finally, we connect work identity salience with subsequent leadership status, including contextual moderators that enhance or undermine these effects (i.e., inclusive organizational climate and mega-threats, respectively). We conclude with theoretical and practical implications of this research, including for workforce efficiency and social sustainability. We also highlight calls for future research stemming from our review [e.g., sustainability critical events and gendered analyses for (more) accurate science] as well as fruitful research areas and innovative practices at the work-non-work interface for professionals on the path to leadership.
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  • 文章类型: Journal Article
    目的:在常规社区医院护理中,很少有证据表明晕厥对植入式心律转复除颤器(ICD)患者的影响。这项单中心回顾性研究旨在评估连续ICD患者晕厥的发生率和预后意义。
    结果:收集了2009年1月至2019年12月期间接受首次ICD植入的连续患者的数据。主要终点是全因晕厥的首次发生,全因死亡率,和所有原因的住院治疗。多变量Cox比例风险模型用于识别与晕厥相关的危险因素,并分析随后的死亡和住院风险。最终分析包括1003名患者(58%的一级预防)。在平均1519±1055天的随访中,106例(10.6%)晕厥,304人死亡(30.3%),477例(47.5%)因任何原因住院.在针对基线变量进行调整的分析中,晕厥的首次发生与死亡率(HR2.82,P<0.001)和首次住院(HR2.46,P=0.002)的风险显著增加相关.
    结论:在ICD受者中晕厥是常见的,并且与不良预后相关,与基线变量和ICD程序无关。晕厥的发生与死亡率和住院风险的显着增加有关。
    There is little evidence of the impact of syncope in implantable cardioverter-defibrillator (ICD) patients in routine community hospital care. This single-centre retrospective study sought to evaluate the incidence and prognostic significance of syncope in consecutive ICD patients.
    Data were collected on consecutive patients undergoing first ICD implantation between January 2009 and December 2019. The primary endpoints were the first occurrence of all-cause syncope, all-cause mortality, and all-cause hospitalization. Multivariate Cox proportional hazard models were used to identify risk factors associated with syncope and to analyse the subsequent risk of mortality and hospitalization. 1003 patients (58% primary prevention) were included in the final analysis. During a mean follow-up of 1519 ± 1055 days, 106 (10.6%) experienced syncope, 304 died (30.3%), and 477 (47.5%) were hospitalized for any cause. In an analysis adjusted for baseline variables, the first occurrence of syncope was associated with a significantly increased risk of mortality (HR 2.82, P < 0.001) and the first occurrence of hospitalization (HR 2.46, P = 0.002).
    Syncope in ICD recipients is common and associated with a poor prognosis irrespective of baseline variables and ICD programming. The occurrence of syncope is associated with a significant increase in the risk of mortality and hospitalization.
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  • 文章类型: Journal Article
    粮食系统越来越容易受到干扰和冲击,预计未来还会增加。最近,乌克兰战争和新冠肺炎疫情增加了人们对能否以稳定的价格确保粮食供应的担忧。本文提出了一个粮食系统复原力框架,以促进国家预见系统,以更好地应对冲击和破坏。我们的研究确定了韧性的四个关键要素:通过科学和沟通进行系统思考;活动和网络冗余;生产和合作伙伴的多样性;和缓冲策略。提高芬兰粮食系统韧性的三个国家手段包括国内蛋白质作物生产,可再生能源生产,创造就业的措施。初级生产被认为是粮食系统韧性的基石,因此,它面临的冲击和破坏需要足够和多样化的国内生产量,由可用的国内可再生能源支持。强调了粮食系统中不同行为者之间的对话,以格式化情况并做出快速反应。我们的研究表明,在某种程度上,粮食系统的集中和相互依存增加了对话与合作。对于关键资源,在意外生产或市场中断的情况下,充足的储备库存在短期内缓冲中断。在粮食系统中引入和加强已确定的复原力要素和手段,需要制定一项更加全面和连贯的粮食系统政策,承认并强调复原力和效率。
    UNASSIGNED:在线版本包含补充材料,可在10.1007/s10669-022-09889-5获得。
    Food systems are increasingly exposed to disruptions and shocks, and they are projected to increase in the future. Most recently, the war in Ukraine and Covid-19 pandemic has increased concerns about the ability to secure the availability of food at stable prices. This article presents a food system resilience framework to promote a national foresight system to better prepare for shocks and disruptions. Our study identified four key elements of resilience: system thinking through science and communication; redundancy of activities and networks; diversity of production and partners; and buffering strategies. Three national means to enhance resilience in the Finnish food system included domestic protein crop production, renewable energy production, and job creation measures. Primary production was perceived as the cornerstone for food system resilience, and the shocks and disruptions that it confronts therefore call for a sufficient and diverse domestic production volume, supported by the available domestic renewable energy. A dialogue between different actors in the food system was highlighted to format a situational picture and enable a rapid response. Our study suggests that to a certain point, concentration and interdependence in the food system increase dialogue and cooperation. For critical resources, sufficient reserve stocks buffer disruptions over a short period in the event of unexpected production or market disruptions. Introducing and strengthening the identified resilience elements and means to the food system call for the preparation of a more holistic and coherent food system policy that acknowledges and emphasises resilience alongside efficiency.
    UNASSIGNED: The online version contains supplementary material available at 10.1007/s10669-022-09889-5.
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  • 文章类型: Journal Article
    在本文中,我们利用加纳股票市场(GSE)的每日股票回报来检验新冠肺炎大流行对市场波动的影响。我们从1月2日开始考虑回报波动,2018年12月31日,2021年,并将其分为两个时期-前COVID-19时期和COVID-19时期。利用指数GARCH(EGARCH)模型,我们在所有观察到的时期都发现了杠杆效应。此外,研究表明,COVID-19期间经历了高波动,具有短暂的波动持续性。此外,在COVID-19大流行期间,积极冲击对GSE收益波动的影响比同等幅度的负面消息更显著。
    In this paper, we utilise daily stock returns for the Ghanaian equity market (GSE) to examine the influence of the COVID-19 pandemic on market volatility. We take return volatility from 2nd January, 2018, to 31st December, 2021, and split it into two periods-the pre-COVID-19 period and the COVID-19 period. Utilising the exponential GARCH (EGARCH) model, we discovered leverage effects in all observed periods. Additionally, the research indicates that the COVID-19 period experienced high volatility with a transient volatility persistence. Furthermore, during the COVID-19 pandemic, positive shocks had a more significant impact on the volatility of the GSE\'s returns than negative news of comparable magnitude.
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  • 文章类型: Journal Article
    使用通常用于估计累积超额死亡的方法,我们衡量了COVID-19冲击对英国食品零售商和餐馆销售的影响。为了控制COVID-19的传播,旅行和社交互动受到限制,给零售商带来巨大压力,他们必须适应快速变化的市场。结果显示,在2020年3月至8月期间,COVID-19限制措施使食品零售商的销售额增加了40亿英镑,非商店零售商40亿英镑;非食品商店销售额损失200亿英镑,以及食品和饮料服务营业额损失250亿英镑。
    Using an approach normally used to estimate cumulative excess deaths, we measure the impact of the COVID-19 shock on sales of UK food retailers and restaurants. To control the spread of COVID-19, travel and social interactions were restricted, putting significant pressure on retailers, who had to adapt whilst complying with a fast-changing marketplace. Results show that in the period March-August 2020, COVID-19 restrictions accounted for a £4 billion increase in sales for food retailers, and £4 billion in non-store retailers; and a £20 billion loss in sales in non-food stores, and £25 billion loss in turnover for food and beverage serving services.
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