Recruitment

招聘
  • 文章类型: Journal Article
    本文使用批判性语篇分析来调查人工智能(AI)生成的老年护理护士图像,并考虑观点和看法如何影响护士的招聘和保留。这篇文章展示了老年护理护理的重新情境化,产生隐藏的意识形态,包括允许歧视和剥削的有害陈规定型观念。有人认为,这可能意味着护士在老年护理中需要较少的临床技能,降低在这一领域工作的价值。人工智能依赖于现有的数据集,因此代表了现有的刻板印象和偏见。话语分析突出了可能进一步影响护理招聘和保留的关键问题,并主张加强道德考量,包括在数据验证中使用专家,老年护理服务和护士的描绘方式和价值。
    This article uses critical discourse analysis to investigate artificial intelligence (AI) generated images of aged care nurses and considers how perspectives and perceptions impact upon the recruitment and retention of nurses. The article demonstrates a recontextualization of aged care nursing, giving rise to hidden ideologies including harmful stereotypes which allow for discrimination and exploitation. It is argued that this may imply that nurses require fewer clinical skills in aged care, diminishing the value of working in this area. AI relies on existing data sets, and thus represent existing stereotypes and biases. The discourse analysis has highlighted key issues which may further impact upon nursing recruitment and retention, and advocates for stronger ethical consideration, including the use of experts in data validation, for the way that aged care services and nurses are depicted and thus valued.
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  • 文章类型: Journal Article
    背景:招聘调查一直是一个巨大的挑战,尤其是在一般实践中。
    方法:这里,我们报告了招聘策略,数据收集,PRICOV-19研究的参与率(PR)和代表性,国际比较,横截面,在37个欧洲国家和以色列的一般做法(GP做法)中进行在线调查。
    结果:9个(24%)国家报告了已发布的邀请;19个(50%)与所有GP/GP实践有直接联系;19个(50%)联系了GP/GP实践样本;7个(18%)使用了另一种邀请策略。中位参与率为22%(IQR=10%,28%)。多种邀请策略(P值0.93)和多种增加PR的策略(P值0.64)与PR无关。在(半)农村地区的GP实践,GP实践服务于10,000多名患者,和小组实践的代表性过高(P值<0.001)。PR与初级保健(PC)系统强度之间没有显着相关性[Spearmanr0.13,95%CI(-0.24,0.46);P值0.49];COVID-19发病率[Spearmanr0.19,95%CI(-0.14,0.49);P值0.24],或COVID-19死亡率[Spearmanr0.19,95%CI(-0.02,0.58);P值0.06]在特定国家研究开始前的三个月内。
    结论:我们的主要贡献是描述了PRICOV-19的调查招募和代表性,这是一项重要而新颖的研究。
    BACKGROUND: Recruitment for surveys has been a great challenge, especially in general practice.
    METHODS: Here, we reported recruitment strategies, data collection, participation rates (PR) and representativeness of the PRICOV-19 study, an international comparative, cross-sectional, online survey among general practices (GP practices) in 37 European countries and Israel.
    RESULTS: Nine (24%) countries reported a published invitation; 19 (50%) had direct contact with all GPs/GP practices; 19 (50%) contacted a sample of GPs /GP practices; and 7 (18%) used another invitation strategy. The median participation rate was 22% (IQR = 10%, 28%). Multiple invitation strategies (P-value 0.93) and multiple strategies to increase PR (P-value 0.64) were not correlated with the PR. GP practices in (semi-) rural areas, GP practices serving more than 10,000 patients, and group practices were over-represented (P-value < 0.001). There was no significant correlation between the PR and strength of the primary care (PC) system [Spearman\'s r 0.13, 95% CI (-0.24, 0.46); P-value 0.49]; the COVID-19 morbidity [Spearman\'s r 0.19, 95% CI (-0.14, 0.49); P-value 0.24], or COVID-19 mortality [Spearman\'s r 0.19, 95% CI (-0.02, 0.58); P-value 0.06] during the three months before country-specific study commencement.
    CONCLUSIONS: Our main contribution here was to describe the survey recruitment and representativeness of PRICOV-19, an important and novel study.
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  • 文章类型: Journal Article
    背景:小儿腹腔镜手术中肺不张的发生率很高。作者假设,与常规通气相比,使用招募策略或使用持续气道正压可以预防肺不张。
    目的:主要目的是比较在接受腹腔镜手术的儿童中使用三种不同的通气技术通过肺部超声(LUS)诊断的肺不张程度。
    方法:随机,前瞻性三臂试验。
    方法:单一研究所,三级护理,教学医院。
    方法:年龄在10岁以下的ASAPS1和2的儿童接受持续30分钟以上的气腹腹腔镜手术。
    方法:随机分配到三个研究组之一:CG组:调整吸气压力以达到5-8ml/kg的TV,5cmH2O的PEEP,通过手动通气和诱导时无PEEP,调整呼吸频率以维持潮气末二氧化碳(ETCO2)在30-40mmHg之间。RM组:应用在插管后10秒提供30cmH2O的恒定压力的募集操作。术中维持10cmH2O的PEEP。CPAP组:使用机械通气进行PEEP10cmH2O和CPAP10cmH2O的术中维持。
    方法:通过LUS评估闭合时的肺不张评分。
    结果:诱导后,LUS在所有三组中具有可比性。在关闭的时候,RM组(8.6±4.9)和CPAP组(8.8±6.8)的LUS显着低于CG组(13.3±3.8)(p<0.05)。在CG和CPAP组中,闭合时的评分显著高于诱导后.气腹时,RM组(437.1±44.9)和CPAP组(421.6±57.5)的PaO2/FiO2比值明显高于CG组(361.3±59.4)(p<0.05)。
    结论:在儿科患者腹腔镜手术中,在高PEEP的诱导和维持过程中,插管或CPAP后的募集操作与常规通气相比,导致肺不张减少。
    背景:CTRI/2019/08/02058。
    BACKGROUND: There is a high incidence of pulmonary atelectasis during paediatric laparoscopic surgeries. The authors hypothesised that utilising a recruitment manoeuvre or using continuous positive airway pressure may prevent atelectasis compared to conventional ventilation.
    OBJECTIVE: The primary objective was to compare the degree of lung atelectasis diagnosed by lung ultrasound (LUS) using three different ventilation techniques in children undergoing laparoscopic surgeries.
    METHODS: Randomised, prospective three-arm trial.
    METHODS: Single institute, tertiary care, teaching hospital.
    METHODS: Children of ASA PS 1 and 2 up to the age of 10 years undergoing laparoscopic surgery with pneumoperitoneum lasting for more than 30 min.
    METHODS: Random allocation to one of the three study groups: CG group: Inspiratory pressure adjusted to achieve a TV of 5-8 ml/kg, PEEP of 5 cm H2O, respiratory rate adjusted to maintain end-tidal carbon dioxide (ETCO2) between 30-40 mm Hg with manual ventilation and no PEEP at induction. RM group: A recruitment manoeuvre of providing a constant pressure of 30 cm H2O for ten seconds following intubation was applied. A PEEP of 10 cm H2O was maintained intraoperatively. CPAP group: Intraoperative maintenance with PEEP 10 cm H2O with CPAP of 10 cm H2O at induction using mechanical ventilation was done.
    METHODS: Lung atelectasis score at closure assessed by LUS.
    RESULTS: Post induction, LUS was comparable in all three groups. At the time of closure, the LUS for the RM group (8.6 ± 4.9) and the CPAP group (8.8 ± 6.8) were significantly lower (p < 0.05) than the CG group (13.3 ± 3.8). In CG and CPAP groups, the score at closure was significantly higher than post-induction. The PaO2/FiO2 ratio was significantly higher (p < 0.05) for the RM group (437.1 ± 44.9) and CPAP group (421.6 ± 57.5) than the CG group (361.3 ± 59.4) at the time of pneumoperitoneum.
    CONCLUSIONS: Application of a recruitment manoeuvre post-intubation or CPAP during induction and maintenance with a high PEEP leads to less atelectasis than conventional ventilation during laparoscopic surgery in paediatric patients.
    BACKGROUND: CTRI/2019/08/02058.
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  • 文章类型: Journal Article
    目的:本研究探讨了社交媒体广告作为压力性尿失禁(SUI)女性招募策略的机会。
    方法:这项可行性研究是一项更大的临床试验的一部分,该临床试验是对SUI治疗患者决策辅助的影响。我们开始了为期61天的社交媒体广告活动,招募女性参加审判。我们研究的主要结果是入学速度。次要结果涉及每位参与者的成本,基线人口统计比较和广告系列绩效指标。此外,我们采访了招募的参与者,以确定我们方法的促进者和障碍。
    结果:招募了10名参与者,其中8人完成了完整的研究方案(2份问卷间隔6个月)。入学速度,每月4.0名研究参与者,与通过常规方法每月平均2.7名参与者相比,速度更快。该活动每天点击广告87次,其中1%的女性通过联系我们对我们的研究表现出兴趣。从点击到全员参与的整体转化率为0.2%。每位参与者的费用为112欧元。除了更高的年龄,社交媒体招募的参与者的人口统计与传统纳入的人群相当.定性分析确定了更多面向用户的注册程序和潜在的参与者利益作为社交媒体招聘的促进者。
    结论:这项研究表明,在SUI女性的试验中,社交媒体招募是可行的。它可以加速招募合格的参与者。优化注册程序以更好地满足参与者的需求和招聘福利可能会提高参与度和成本效益。试用注册ID2017-3540。
    OBJECTIVE: This study explores the opportunities of social media advertisements as a recruitment strategy in women with stress urinary incontinence (SUI).
    METHODS: This feasibility study was part of a larger clinical trial on the effects of a patient decision aid for SUI treatment. We started a 61-day social media advertisement campaign to recruit women for the trial. The primary outcome of our study was enrolment pace. Secondary outcomes involved cost per participant, baseline demographic comparison and ad campaign performance metrics. Additionally, we interviewed recruited participants to identify the facilitators and barriers of our approach.
    RESULTS: Ten participants were recruited, of whom 8 completed the full study protocol (2 questionnaires 6 months apart). The enrolment pace, 4.0 study participants per month, was faster compared to the average of 2.7 participants per month through conventional methods. The campaign reached 87 clicks on the advertisement per day and 1 % of these women showed interest in our study by contacting us. The overall conversion rate from click to full participation was 0.2 %. The costs per participant were €112. Besides higher age, the demographics of the social media recruited participants were comparable to the conventional inclusions. Qualitative analysis identified more user-oriented enrolment procedures and potential participant benefit as facilitators of social media recruitment.
    CONCLUSIONS: This study shows that social media recruitment can be feasible in trials for women with SUI. It can accelerate recruitment of eligible participants. Optimising the enrolment procedure to better meet participants\' needs and recruitment benefits may improve participation and cost-effectiveness. Trial registration ID 2017-3540.
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  • 文章类型: Journal Article
    目的:全球卫生研究人员有责任以文化上尊重和安全的方式进行伦理研究。这项工作的目的是描述我们在巴基斯坦的招聘和保留经验,一个中低收入国家。
    方法:我们借鉴了两项研究,其中包括2161名低风险孕妇的组合样本,这些孕妇参加了一项试点(n=300)和一项更大的(n=1861)前瞻性研究。在四个中心之一(花园,海得拉巴,Kharadar,卡拉奇阿加汗大学医院的Karimabad),巴基斯坦。
    结果:我们遇到的挑战包括经济困难和获得医疗保健;妇女在家庭中的地位;安全问题和时间承诺;研究过程中的误解和不信任;以及与抽血有关的问题。为了缓解这些挑战,我们开发了文化上可接受的学习激励措施,让家庭成员参与研究参与的决策过程,与参与者\'妇产科医生合作,容纳场外研究访问,将研究访问与定期产前护理访问相结合,以及一些女性与抽血相关的修改研究参与。
    结论:实施这些缓解策略可提高招聘和保留成功率,我们相信,提出的解决方案将支持未来的科学家应对社会文化挑战,同时在巴基斯坦和其他中低收入国家开展合作研究项目。
    OBJECTIVE: Global health researchers have a responsibility to conduct ethical research in a manner that is culturally respectful and safe. The purpose of this work is to describe our experiences with recruitment and retention in Pakistan, a low-middle-income country.
    METHODS: We draw on two studies with a combined sample of 2161 low-risk pregnant women who participated in a pilot (n = 300) and a larger (n = 1861) prospective study of psychological distress and preterm birth at one of four centers (Garden, Hyderabad, Kharadar, Karimabad) of the Aga Khan University Hospital in Karachi, Pakistan.
    RESULTS: Challenges we encountered include economic hardship and access to healthcare; women\'s position in the family; safety concerns and time commitment; misconceptions and mistrust in the research process; and concerns related to blood draws. To mitigate these challenges, we developed culturally acceptable study incentives, involved family members in the decision-making process about study participation, partnered with participants\' obstetrician-gynecologists, accommodated off site study visits, combined research visits with regular prenatal care visits, and modified research participation related to blood draws for some women.
    CONCLUSIONS: Implementation of these mitigation strategies improved recruitment and retention success, and we are confident that the solutions presented will support future scientists in addressing sociocultural challenges while embarking on collaborative research projects in Pakistan and other low-middle-income countries.
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  • 文章类型: Journal Article
    背景:招募足够和不同的参与者参与阿尔茨海默病和相关痴呆的临床研究仍然是一个巨大的挑战。本手稿的主要目标是提供多样化研究招募方法的概述,并提供在临床研究招募中实现更大多样性的几种方法的案例示例。
    方法:堪萨斯大学阿尔茨海默病研究中心(KUADRC)开发了MyAllianceforBrainHealth(MyAlliance),面向服务的招聘模式。MyAlliance由初级保健提供者网络组成,患者和家庭的网络,和社区组织网络,每个人都为相关方提供量身定制的价值,同时促进研究推荐。
    结果:我们回顾了三种方法,以鼓励增加临床研究参与的多样性。初步结果显示,在研究注册表中,代表性不足的参与者从17%增加到27%。由研究注册中心支持的研究的入学人数增加了51%,来自代表性不足的社区的参与者比例增加了。
    结论:MyAlliance转移了权力,资源,和社区倡导者的知识,促进大脑健康意识和研究参与,并要求大量的财务投资和行政承诺。MyAlliance为建设可持续发展提供了宝贵的经验,以社区为中心的研究招聘基础设施,强调本地化参与和文化理解的重要性。
    MyAlliance导致农村地区代表性不足的种族和族裔群体以及个人的代表性显着增加。以服务为导向的方法促进了社区的长期参与和建立信任,扩大学术医疗中心和社区组织之间的伙伴关系。虽然有效,MyAlliance需要大量的财务投资,包括基础设施开发在内的成本,工作人员支持,合作伙伴组织补偿,和促销活动,强调包容性研究招聘工作的资源密集型性质。
    BACKGROUND: Recruitment of sufficient and diverse participants into clinical research for Alzheimer\'s disease and related dementias remains a formidable challenge. The primary goal of this manuscript is to provide an overview of an approach to diversifying research recruitment and to provide case examples of several methods for achieving greater diversity in clinical research enrollment.
    METHODS: The University of Kansas Alzheimer\'s Disease Research Center (KU ADRC) developed MyAlliance for Brain Health (MyAlliance), a service-oriented recruitment model. MyAlliance comprises a Primary Care Provider Network, a Patient and Family Network, and a Community Organization Network, each delivering tailored value to relevant parties while facilitating research referrals.
    RESULTS: We review three methods for encouraging increased diversity in clinical research participation. Initial outcomes reveal an increase in underrepresented participants from 17% to 27% in a research registry. Enrollments into studies supported by the research registry experienced a 51% increase in proportion of participants from underrepresented communities.
    CONCLUSIONS: MyAlliance shifts power, resources, and knowledge to community advocates, promoting brain health awareness and research participation, and demands substantial financial investment and administrative commitment. MyAlliance offers valuable lessons for building sustainable, community-centered research recruitment infrastructure, emphasizing the importance of localized engagement and cultural understanding.
    UNASSIGNED: MyAlliance led to a significant increase in the representation of underrepresented racial and ethnic groups and individuals from rural areas.The service-oriented approach facilitated long-term community engagement and trust-building, extending partnerships between an academic medical center and community organizations.While effective, MyAlliance required substantial financial investment, with costs including infrastructure development, staff support, partner organization compensation, and promotional activities, underscoring the resource-intensive nature of inclusive research recruitment efforts.
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  • 文章类型: Journal Article
    美国已经进行了有限的研究,研究了影响农村地区医疗保健提供者招聘的因素,由于社区差异,需要进行社区一级的调查。这项研究的目的是探讨在爱达荷州北部农村社区招募医疗保健提供者的因素。使用经过重新调整的护理社区Apgar问卷(NCAQ)从50家医疗保健提供者那里收集数据,以评估影响提供者招募的项目。项目分为五个因素:地理,经济,实践范围,医疗支持,以及设施和社区支持课程。医疗保健提供者根据感知的重要性以及招聘的优势或挑战性对项目进行排名。“社区阿普加”分数是使用优势/挑战和重要性分数计算的综合分数。在我们的样本中,医疗支持被评为最重要的一类。此外,设施和社区支持被评为最高优势类,并具有最有影响力的阿普加分数,这意味着它包含了最重要的优势和挑战。我们的发现表明,这些类别包含与农村地区招募提供者有关的主导因素。寻求改善医疗服务提供者招聘的农村医疗机构应考虑这些因素对其人口的潜在影响。应该对美国各地不同的农村样本进行进一步的调查,以便能够比较研究结果。
    Limited U.S. research has been conducted examining factors affecting healthcare provider recruitment in rural settings, necessitating community-level investigations due to community differences. The aim of this study was to explore the factors involved in healthcare provider recruitment in a rural community in Northern Idaho. A retooled version of the Nursing Community Apgar Questionnaire (NCAQ) was used to collect data from 50 healthcare providers to assess items influencing provider recruitment. Items were categorized into five factors: geographic, economic, scope of practice, medical support, and facility and community support classes. Healthcare providers ranked items based on perceived importance and how advantageous or challenging it was to recruitment. A \"Community Apgar\" score is a composite score calculated using the advantage/challenge and importance scores. In our sample, medical support was rated as the most important class. Additionally, facility and community support was rated as the highest advantage class and had the most impactful Apgar scores, meaning it contained the most important advantage and challenge. Our findings suggest that these classes contain dominant factors related to the recruitment of providers in rural areas. Rural healthcare organizations seeking to improve the recruitment of healthcare providers should consider the potential impact of these factors on their population. Further investigations should be conducted on diverse rural samples across the U.S. to enable comparisons of research findings.
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  • 文章类型: Journal Article
    背景:接受癌症诊断是一种深刻且通常非常紧张的经历。很少有研究在接受新的癌症诊断之前前瞻性地招募患者,并包括配偶或伴侣。
    目的:夫妻应对研究的目的是了解接受诊断性活检和接受新的癌症诊断对患者及其配偶或伴侣的生活质量(QoL)的影响。以及他们关系的质量。本协议文件描述了研究设计并评估了招募和保留的可行性。
    方法:研究人员回顾了合作医生的时间表,使用特定的相遇代码来识别计划进行乳腺或前列腺活检的患者。通过电子健康记录对潜在参与者进行预筛选,并在活检程序前至少2至3周发送招募信。患者随后接受电话筛查以确定资格。登记的患者为研究人员提供了其配偶或伴侣的联系信息。所有同意书均在网上完成。在收到活检结果(基线)之前在线完成调查,以及活检后1、3、6和9个月。研究人员从事持续的,与参与者的个性化联系,并通过电话和电子邮件发送评估完成提醒。
    结果:共有2294名接受乳腺或前列腺活检的患者被确认,69%(n=1582)的患者在电子健康记录预筛查后有资格接受电话筛查。在接受电话筛查的431名患者中,75%(n=321)有资格参加。在符合条件的病人中,72%(n=231)的参与者和82%(n=190)的参与者有伴侣或配偶。共有77%(34/44)的接受癌症诊断的患者和72%(26/36)的配偶或伴侣被保留了9个月,而80%(53/66)接受良性诊断的患者和68%(42/62)的伴侣被保留。
    结论:对接受诊断性活检的患者及其合作伙伴进行前瞻性招募是可行的,需要与提供者进行战略合作,并需要研究人员进行协同的预筛查和招募工作。重要的是,这项研究能够在线进行所有研究活动,而不会中断临床工作流程,也不需要患者及其配偶或伴侣进入实验室.应考虑活检与癌症诊断的比例,这可能因癌症类型而异。需要进行前瞻性研究,并可以告知我们有能力为面临可能的癌症诊断的夫妇提供更早的有效支持。未来的研究应该检查在QoL研究中受到较少关注的其他肿瘤类型,包括自我报告措施以外的行为和神经生物学评估,并跟踪超过9个月的夫妇,以检查对QoL的长期影响。
    DERR1-10.2196/52361。
    BACKGROUND: Receiving a diagnosis of cancer is a profound and often very stressful experience. Few studies have prospectively recruited patients prior to receiving a new diagnosis of cancer and included spouses or partners.
    OBJECTIVE: The aim of the Couples Cope Study is to understand the impact of undergoing a diagnostic biopsy and receiving a new cancer diagnosis on quality of life (QoL) in both patients and their spouses or partners, as well as on the quality of their relationship. This protocol paper describes the study design and assesses the feasibility of recruitment and retention.
    METHODS: Study staff reviewed the schedules of collaborating physicians using specific encounter codes to identify patients scheduled for breast or prostate biopsies. Potential participants were prescreened via the electronic health record and sent a recruitment letter at least 2 to 3 weeks prior to their biopsy procedure. Patients subsequently underwent a phone screening to determine eligibility. Patients who enrolled provided study staff with contact information for their spouses or partners. All consent forms were completed online. Surveys were completed online prior to receiving the biopsy results (baseline), and at 1, 3, 6, and 9 months after the biopsy. Study staff engaged in ongoing, personalized contact with participants and sent assessment completion reminders via phone and email.
    RESULTS: A total of 2294 patients undergoing a breast or prostate biopsy were identified and 69% (n=1582) were eligible for phone screening following electronic health record prescreening. Of the 431 patients who underwent phone screening, 75% (n=321) were eligible to participate. Of the eligible patients, 72% (n=231) enrolled and 82% (n=190) of enrolled patients had an accompanying partner or spouse who also enrolled. A total of 77% (34/44) of patients who received a cancer diagnosis and 72% (26/36) of their spouses or partners were retained through 9 months, while 80% (53/66) of patients who received a benign diagnosis and 68% (42/62) of their partners were retained.
    CONCLUSIONS: Prospective recruitment of patients undergoing diagnostic biopsy and their partners is feasible and requires both strategic collaboration with providers and concerted prescreening and recruitment efforts by study staff. Importantly, this study was able to conduct all study activities online without disrupting clinical workflow and without requiring patients and their spouses or partners to come into the laboratory. Consideration should be given to the ratio of biopsies to cancer diagnoses, which can vary significantly by cancer type. Prospective studies are needed and can inform our ability to provide effective support earlier to couples facing a possible cancer diagnosis. Future studies should examine other tumor types that have received less attention in QoL studies, include behavioral and neurobiological assessments beyond self-report measures, and follow couples beyond 9 months in order to examine long-term effects on QoL.
    UNASSIGNED: DERR1-10.2196/52361.
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  • 文章类型: Journal Article
    长期以来,人们一直呼吁老年人参与研究和开发过程,但尚未充分付诸实践。此外,参与往往很晚,也不是特别密集,因此,某些老年人群体在健康技术(HT)的发展中代表性不足。异质性,例如,在城市和农村人口之间,参与的机会和动机也很少被考虑在内。这项研究的目的是调查难以接触的老年人在HT研究和开发过程中的参与形式和阶段。
    使用焦点小组和电话访谈对乘数进行了定性研究,并在下萨克森州西北部的一个城市和一个邻近的农村地区进行了研究。德国。使用演绎归纳类别形成对数据进行内容分析。
    17名参与者(13名女性)参加了这项研究(平均年龄61,33-73岁)。来自这两个领域的参与者确定了参与研究和开发过程的特定形式和阶段。难以接触群体的更长时间的参与形式以及农村地区老年人技术的开发过程被视为挑战。需要被动和主动访问策略,以在研发过程中实现足够的异质性。可信赖的乘数可以在获得难以接触的老年人方面发挥重要作用,而且在研究过程中。除了促进因素(例如,特定年龄的学习材料),还指出了接触焦虑等抑制因素。只有城市参与者提到财政/物质激励措施和社区作为可能的动机。
    结果从乘数的角度提供了重要的见解。它们显示了农村地区和难以接触的老年人在获取和参与方面的特殊性。许多老年人可能对研究项目和HT有不确定性。乘数可以发挥关键作用,帮助减少未来的这些不确定性。
    UNASSIGNED: The participation of older people in research and development processes has long been called for but has not been sufficiently put into practice. In addition, participation is often late and not particularly intensive, so that certain older groups of people are underrepresented in the development of health technologies (HT). Heterogeneity, e.g., between urban and rural populations, in access to and motivation for participation is also rarely taken into account. The aim of this study was to investigate form and phases of participation for hard-to-reach older people in the research and development process of HT.
    UNASSIGNED: The qualitative study among multipliers was conducted using focus groups and telephone interviews and took place in a city and an adjacent rural area in northwestern Lower Saxony, Germany. A content analysis of the data was undertaken using deductive-inductive category formation.
    UNASSIGNED: Seventeen participants (13 female) took part in the study (median age 61, 33-73). Participants from both areas identified particular forms and phases of participation in the research and development process. Longer forms of participation for hard-to-reach groups and the development process of technologies for older people from the rural area were viewed as challenges. Passive and active access strategies are needed to achieve sufficient heterogeneity in the research and development process. Trusted multipliers can play an important role in gaining access to hard-to-reach older people, but also during the research process. Apart from facilitating factors (e.g., age-specific study materials), inhibiting factors such as contact anxieties are also indicated. Only urban participants mention financial/material incentives and community as possible motivations.
    UNASSIGNED: The results provide important insights from the perspective of multipliers. They show specificities in access and participation for rural areas and for hard-to-reach older people. Many older people may have uncertainties about research projects and HT. Multipliers can assume a key role to help reduce these uncertainties in the future.
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  • 文章类型: Journal Article
    招募和保留对阿尔茨海默病(AD)研究构成了重大挑战。已提出将AD生物标志物结果返回给参与者作为改善招募和保留的手段。我们提出了与参与者满意度相关的发现,实用程序,和对研究态度的影响从淀粉样蛋白正电子发射断层扫描(PET)披露子研究在威斯康星州注册阿兹海默症预防(WRAP)。
    99名认知未受损的WRAP参与者学习了他们的淀粉样蛋白PET结果(平均年龄±SD=72.0±4.8)。衡量想要学习结果的原因,学习理解,结果效用,参观满意度,研究态度,收集未来研究的入学意愿。组间,进行卡方分析以确定结果类型的差异(升高与淀粉样蛋白PET结果没有升高)在研究理解中,结果效用,参观满意。线性混合效应模型用于评估研究态度和入学意愿随时间的变化,淀粉样蛋白结果类型(升高/未升高),和他们的互动。
    想要学习淀粉样蛋白PET结果的最常见原因是“希望为阿尔茨海默病痴呆症的研究做出贡献”和“告知预防措施[一个]可能采取的措施(例如,改变饮食,锻炼,或其他生活方式的改变)。“总的来说,参与者报告了解结果并发现学习结果有用.对考察访问的满意度非常高,超过80%的人同意访问的有用性和满意度。在学习结果升高和未升高的参与者之间几乎没有差异。在研究过程中,与未获得升高结果的参与者相比,获得升高的淀粉样蛋白PET结果的参与者报告更愿意参加药物试验(β:0.12,p=0.01)和生活方式干预(β:0.10,p=0.02).
    正式纳入披露实践可能会鼓励AD研究中的参与者招募和保留。
    参与者希望了解他们的淀粉样蛋白结果,为研究做出贡献。总体上对披露和披露后访问的满意度很高。返回AD生物标志物可以增加参与研究的意愿。
    UNASSIGNED: Recruitment and retention pose a significant challenge to Alzheimer\'s disease (AD) research. Returning AD biomarker results to participants has been proposed as a means to improve recruitment and retention. We present findings related to participant satisfaction, utility, and impact on research attitudes from the amyloid positron emission tomography (PET) disclosure sub-study within the Wisconsin Registry for Alzheimer\'s Prevention (WRAP).
    UNASSIGNED: Ninety-nine cognitively unimpaired WRAP participants learned their amyloid PET results (mean age ± SD = 72.0 ± 4.8). Measures of reasons for wanting to learn results, study comprehension, result utility, visit satisfaction, research attitudes, and future study enrollment willingness were collected. Between-group, chi-squared analysis was conducted to determine differences by result type (elevated vs. not elevated amyloid PET result) in study comprehension, result utility, and visit satisfaction. Linear mixed-effects modeling was used to evaluate changes in research attitudes and enrollment willingness as a function of time, amyloid result type (elevated/not elevated), and their interaction.
    UNASSIGNED: The reasons most frequently endorsed for wanting to learn amyloid PET result was a \"desire to contribute to research on Alzheimer\'s disease dementia\" and \"to inform preventative measures [one] might take (e.g., change diet, exercise, or other lifestyle changes).\" Overall, participants reported understanding the results and found learning them useful. Satisfaction with the study visits was overwhelmingly high, with over 80% agreeing with visit usefulness and their satisfaction. Few differences were found between participants who learned an elevated and not elevated result. Over the course of the study, participants who learned an elevated amyloid PET result reported higher willingness to enroll in drug trials (beta: 0.12, p = 0.01) and lifestyle interventions (beta: 0.10, p = 0.02) compared to participants who learned a not elevated result.
    UNASSIGNED: Formal incorporation of disclosure practices may encourage participant recruitment and retention within AD research.
    UNASSIGNED: Participants wanted to learn their amyloid results to contribute to research.Satisfaction with disclosure and post-disclosure visits was high overall.Returning AD biomarkers can increase willingness to participate in research.
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