未经证实:意外的麻醉相关并发症是门诊手术最令人恐惧的结果。一个潜在的罪魁祸首是假胆碱酯酶缺乏症,最常见的表现是持续性呼吸暂停,需要长时间的机械通气。我们报告了孟加拉人假胆碱酯酶缺乏症的首例病例,以及对眼科假胆碱酯酶缺乏症的首次系统评价。这篇综述分析了流行病学,病因,介绍,评估,和治疗假胆碱酯酶缺乏症。
未经评估:在PubMed中进行了搜索,Embase,和Medline至2022年8月的有关眼科假胆碱酯酶缺乏症的出版物。总的来说,689项研究由两名独立审稿人筛选,26篇全文研究纳入资格。19项研究合格,并纳入最终分析。
未经证实:在确认的16例假胆碱酯酶缺乏症病例中,9人(56%)是药物诱导的,四个(25%)是遗传性缺陷,在其中一个(6%)案例中,原因无法确定。在两个(13%)案例中,假胆碱酯酶缺乏症无法确认或排除。术后呼吸暂停的持续时间为10分钟至14小时。持续通气支持是所有病例的主要治疗方法,所有患者均完全康复。
未经证实:假胆碱酯酶缺乏症是一种罕见的,但可能是致命的,导致长时间呼吸暂停的麻醉并发症,呼吸窘迫,和对呼吸机的依赖。眼科医生应该意识到这种情况,尤其是在规划门诊程序时,因为门诊中心管理长期术后并发症的资源可能有限。
UNASSIGNED: Unexpected anesthesia-related complications are among the most feared outcomes of ambulatory surgery. One potential culprit is
pseudocholinesterase deficiency, which most commonly presents with protracted apnea, necessitating prolonged mechanical ventilation. We report the first case of
pseudocholinesterase deficiency in a Bengali person and the first systematic review of
pseudocholinesterase deficiency in ophthalmology. This review analyzed the epidemiology, etiologies, presentation, evaluation, and treatment of pseudocholinesterase deficiency.
UNASSIGNED: Searches were conducted in PubMed, Embase, and Medline through August of 2022 for publications related to pseudocholinesterase deficiency in ophthalmology. In total, 689 studies were screened by two independent reviewers with 26 full-text articles examined for inclusion eligibility. Nineteen studies were eligible and included in the final analysis.
UNASSIGNED: Of the 16 identified cases of
pseudocholinesterase deficiency, nine (56%) were drug-induced, four (25%) were inherited deficiencies, and in one (6%) of the cases, the cause could not be determined. In two (13%) cases,
pseudocholinesterase deficiency could not be confirmed or ruled out. The duration of post-operative apnea ranged from 10 minutes to 14 hours. Continued ventilatory support was the main treatment for all cases and all patients made a full recovery.
UNASSIGNED: Pseudocholinesterase deficiency is a rare, but potentially fatal, anesthetic complication that results in prolonged apnea, respiratory distress, and dependency on ventilators. Ophthalmologists should remain aware of this condition, especially when planning outpatient procedures, as ambulatory centers may have limited resources for managing prolonged post-operative complications.