背景:失眠是一种常见的睡眠障碍,在情境中影响很大一部分人群,经常性,或慢性方式。在加拿大,据估计,13%的人口患有这种疾病。
目的:本文献综述的主要目的是确定和描述有关药剂师管理失眠的作用和影响的研究。
方法:PubMed®,搜索EMBASE®和CINALHComplete以提取1月1日之间发表的文章,1990年和2020年5月28日。药剂师对失眠管理的作用和影响的研究,法语和英语,描述性或定量性,包括有或没有对照组。没有将失眠作为主要主题或失眠是次要疾病的文章被排除在外,会议摘要和研究没有显示具体结果。提取了以下变量:作者,研究类型,持续时间,location,参与者的样本量和特征,药剂师干预措施的描述,限制和偏见,评估结果和结果。用DEPICT2评估药剂师干预描述的质量。
结果:我们的综述确定了2006年至2018年发表的八篇文章,评估了14种类型的结果和41种不同的结果。总共37%(7/19)的定量结果有统计学意义的阳性结果,关于失眠的资格,症状和适当的使用。在社区药房进行了六项研究。质量评分在11个中的8到10之间变化。
结论:关于药剂师管理失眠的作用和影响的数据很少。药剂师可以产生积极的影响,特别是在社区药房执业时。鉴于有限的数据和失眠的患病率,这似乎与投资于这种情况的药物评估研究有关。
BACKGROUND: Insomnia is a common sleep disorder that affects a large portion of the population in a situational, recurrent, or chronic way. In Canada, it is estimated that 13% of the population suffers from it.
OBJECTIVE: The primary objective of this literature review is to identify and describe studies dealing with the role and impact of the management of insomnia by a pharmacist.
METHODS: PubMed®, EMBASE® and CINALH Complete were searched to extract articles published between January 1st, 1990 and May 28, 2020. Studies on the role and impact of management of insomnia by a pharmacist, in French and English, descriptive or quantitative, with or without control group were included. Articles that did not deal with insomnia as the primary topic or where insomnia is a secondary condition were excluded, conference abstracts and studies showing no concrete results. The following variables were extracted: author, type of study, duration, location, sample size and characteristics of participants, description of pharmacist interventions, limits and biases, outcomes assessed and results. The quality of the pharmacists\' interventions description was evaluated with DEPICT2.
RESULTS: Our review identified eight articles published from 2006 to 2018 evaluating 14 types of outcomes and 41 separate outcomes. A total of 37% (7/19) of the quantitative outcomes had statistically significant positive results, regarding insomnia qualification, symptoms and adequate use. Six studies were conducted in community pharmacy. The quality score varied between 8 and 10 out of 11.
CONCLUSIONS: There is little data on the role and impact of the management of insomnia by a pharmacist. The pharmacist can have a positive impact, particularly when practicing in a community pharmacy. Given the limited data and the prevalence of insomnia, it appears relevant to invest in pharmaceutical evaluative research for this condition.