Peritonsillar abscess

扁桃体周围脓肿
  • 文章类型: Journal Article
    目的:这项研究的目的是研究德国Covid-19大流行和封锁政策对德国三级转诊中心扁桃体周围脓肿的频率和治疗的影响。
    方法:这项回顾性病例对照研究分析了2018年3月1日至2022年8月30日在奥格斯堡耳鼻喉科大学医院治疗的所有扁桃体周围脓肿病例,德国,通过脓肿扁桃体切除术和/或切口引流。使用基于德国医院薪酬体系研究所的代码收集数据并将其与Covid-19严格性指数相关联。在排除303例之后,研究了975例脓肿扁桃体切除术和切口引流病例,第一个德国封锁作为截止日期。无论是否与Covid-19共感染,都保持了治疗算法。
    结果:总共174例患者接受了脓肿扁桃体切除术作为治疗,而801例患者行切开引流。在德国第一次封锁之前,452例患者行切口引流。自从大流行以来,记录了349例切口引流(OR=0.54,95%-CI[0.27-0.86],p=0.04),尽管所有耳鼻喉科急症的扁桃体周围脓肿百分比没有显着变化。PTA的平均年龄为39.8岁,复发率为4.0%。研究发现政策措施与治疗之间没有关联(OR=1.00,95%-CI[0.99-1.01],p=0.52)。
    结论:结果表明,尽管Covid-19导致容量下降,但自德国首次封锁以来,奥格斯堡耳鼻喉科大学医院通过脓肿扁桃体切除术治疗扁桃体周围脓肿的患者比例有所增加。在复发率相当的情况下,住院时间仍然可以减少。
    OBJECTIVE: The purpose of this study is to examine the effects of the Covid-19 pandemic and lockdown policies in Germany on frequency and treatment of peritonsillar abscess at a tertiary referral center in Germany.
    METHODS: This retrospective case-control study analyzed all cases of peritonsillar abscess treated from 03/01/2018 until 08/30/2022 at Augsburg ENT University Hospital, Germany, through abscess tonsillectomy and/ or incisional drainage. Data was collected and correlated to Covid-19 Stringency Index using codes based on the Institute for Hospital Remuneration System in Germany. After excluding 303 cases, 975 abscess tonsillectomy and incisional drainage cases were studied, with the first German lockdown serving as cutoff date. Treatment algorithm was maintained regardless of co-infection with Covid-19.
    RESULTS: A total of 174 patients received abscess tonsillectomy as therapy, while 801 patients underwent incisional drainage. Before the first German lockdown, 452 patients received incisional drainage. Since the pandemic, 349 cases of incisional drainage were registered (OR = 0.54, 95%-CI [0.27-0.86], p = 0.04), despite no significant change in the percentage of peritonsillar abscess of all ENT emergencies. The mean age at presentation with PTA was 39.8 years, and the rate of relapse was 4.0%. The study found no association between the scale of policy measures and treatment (OR = 1.00, 95%-CI [0.99-1.01], p = 0.52).
    CONCLUSIONS: The results indicate that, despite the reduction in capacities due to Covid-19, the proportion of patients with peritonsillar abscess treated through abscess tonsillectomy increased at Augsburg ENT University Hospital since the first German lockdown. Hospitalization times could still be reduced with comparable relapse rates.
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  • 文章类型: Journal Article
    目的:扁桃体周围脓肿(PTA)是一种常见的头颈部深间隙感染,可以诊断有或没有计算机断层扫描(CT)。CT有假阳性的风险,导致不必要的脓肿引流尝试没有好处,而没有成像的针吸或开放抽吸可能会导致需要治疗的脓肿错过。本研究通过比较CT和非CT使用的结果,考虑了对疑似PTA患者进行CT扫描的实用性和影响。
    方法:使用TriNetX数据集的回顾性队列分析比较了两个队列的结果:无CT的PTA和有CT的PTA。测量结果包括切口和引流术;腹股沟腺扁桃体切除术;复发性PTA;气道急诊/阻塞;重复急诊(ED)就诊;以及需要抗生素,阿片类药物,或者类固醇.使用队列分析计算赔率比(OR)。
    结果:CT使用组接受抗生素的几率增加(OR3.043,[2.043-4.531]),阿片类药物(OR1.614,[1.138-1.289]),和类固醇(OR1.373,[1.108-1.702]),以及返回ED的可能性较高(OR5.900,[3.534-9.849])并发生复发性PTA(OR1.943,[1.410-2.677])。切口和引流的发生率无显著差异,昆西腺扁桃体切除术,或气道急症/阻塞。
    结论:我们的研究表明,用于PTA诊断的CT扫描与抗生素处方的增加有关,阿片类药物,类固醇,返回ED访问,和复发性PTA。需要进行未来的前瞻性试验,以确定CT扫描的使用是否显示更高的患者视力,从而解释潜在的负面结果。
    方法:II级喉镜,2024.
    OBJECTIVE: Peritonsillar abscess (PTA) is a common deep space head and neck infection, which can be diagnosed with or without computed tomography (CT). CT poses a risk for false positives, leading to unnecessary abscess drainage attempts without benefit, whereas needle or open aspiration without imaging could potentially lead to missed abscess in need of treatment. This study considered the utility and impact of obtaining CT scans in patients with suspected PTA by comparing outcomes between CT and non-CT usage.
    METHODS: Retrospective cohort analysis using TriNetX datasets compared the outcomes of two cohorts: PTA without CT and PTA with CT. Measured outcomes included incision and drainage; quinsy adenotonsillectomy; recurrent PTA; airway emergency/obstruction; repeat emergency department (ED) visits; and need for antibiotics, opiates, or steroids. Odds ratios (OR) were calculated using a cohort analysis.
    RESULTS: The CT usage group had increased odds of receiving antibiotics (OR 3.043, [2.043-4.531]), opiates (OR 1.614, [1.138-1.289]), and steroids (OR 1.373, [1.108-1.702]), as well as a higher likelihood of returning to the ED (OR 5.900, [3.534-9.849]) and developing a recurrent PTA (OR 1.943, [1.410-2.677]). No significant differences were observed in the incidence of incision and drainage, quinsy adenotonsillectomy, or airway emergency/obstruction.
    CONCLUSIONS: Our study indicated that CT scans for PTA diagnosis were associated with increased prescription of antibiotics, opioids, steroids, return ED visits, and recurrent PTA. Future prospective trials are needed to determine if the use of CT scans indicates higher patient acuity that explains the potential negative outcomes.
    METHODS: Level II Laryngoscope, 2024.
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  • 文章类型: Case Reports
    背景技术咽部肿块对迷走神经的压迫是一种有据可查的病症,其可导致窦房结功能障碍(SND)。然而,关于扁桃体脓肿引起的外在迷走神经压迫的文献很少。病例报告一名59岁的女性,有哮喘和慢性咽喉不适病史,因心动过缓被送往急诊科,心悸,和声音的变化。贝类过敏住院后,耳鼻喉科检查显示右扁桃体增大,推荐扁桃体切除术,但是日程安排挑战仍然存在。病人报告有轻微的咽喉疼痛,吞咽困难,声音嘶哑,鼻漏,和劳力性呼吸困难,并被纳入评估扁桃体周围肿块。她被发现心动过缓,心率为47,心电图显示SND。沙丁胺醇和异丙托铵雾化器,以及地塞米松和泮托拉唑,已启动。有了这种治疗,患者症状改善,新心率为68。她在门诊出院,但不幸的是失去了后续行动。结论该病例显示扁桃体脓肿导致的外在迷走神经压迫引起的窦房结功能障碍。迷走神经的压力会引发心动过缓和低血压,可能是由于局部质量效应引起的传入迷走神经信号的代偿性过度放电。早期识别和抗生素治疗对于预防心脏并发症至关重要。临床医生必须对这些外在原因保持警惕,特别是有慢性咽喉痛和心脏症状的患者。需要进一步的研究和病例报告来加深我们对这种罕见但重要的关联的理解。
    BACKGROUND Compression of the vagus nerve by a pharyngeal mass is a well-documented condition that can result in sinus node dysfunction (SND). However, there is scarce literature on extrinsic vagal nerve compression from a tonsillar abscess. CASE REPORT A 59-year-old woman with a history of asthma and chronic throat discomfort presented to the Emergency Department with bradycardia, palpitations, and voice changes. Following a shellfish allergy hospitalization, an otolaryngology evaluation revealed an enlarged right tonsil, recommending tonsillectomy, but scheduling challenges persisted. The patient reported mild throat pain, dysphagia, hoarseness, rhinorrhea, and exertional dyspnea and was admitted for the evaluation of peritonsillar mass. She was found to be bradycardic with a heart rate of 47, with an electrocardiogram revealing SND. Albuterol and ipratropium nebulizers, as well as dexamethasone and pantoprazole, were initiated. With this treatment, the patient symptomatically improved with a new heart rate of 68. She was discharged with outpatient appointments, but was unfortunately lost to follow-up. CONCLUSIONS This case reveals sinus node dysfunction resulting from extrinsic vagal nerve compression by a tonsillar abscess. Pressure on the vagus nerve can trigger bradycardia and low blood pressure, possibly due to compensatory overfiring of afferent vagal nerve signals from local mass effect. Early recognition and antibiotic treatment are essential to prevent cardiac complications. Clinicians must remain vigilant for such extrinsic causes, particularly in patients with chronic sore throat and cardiac symptoms. Further research and case reports are needed to deepen our understanding of this rare yet significant association.
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  • 文章类型: Case Reports
    扁桃体周围脓肿(PTA)是一种主要影响扁桃体周围空间的感染。据估计,每年每10万人中有30人受到影响,15岁和30岁年龄组的患病率较高。PTA的发病机制是有效管理和预防的关键步骤。通常,PTA具有多微生物病因,有氧,和口腔菌群的厌氧菌。文献中的多篇论文研究了PTA病例中克雷伯菌属的发病率。然而,很少有研究在PTA中分离出ozaenae克雷伯菌。我们介绍了一例29岁的患者,该患者因PTA而入院。他在手术室接受了右PTA的切开和引流。用K.ozaenae阳性培养物排出大量的脓液。
    A peritonsillar abscess (PTA) is an infection that primarily affects the peritonsillar space. The incidence is estimated to affect 30 per 100,000 individuals annually, with a higher prevalence between the 15- and 30-year-old age groups. The pathogenesis of a PTA is a crucial step in effective management and prevention. Typically, a PTA has a polymicrobial etiology, aerobic, and anaerobic bacteria of oral flora. Multiple papers in the literature have studied the incidence of Klebsiella species in PTA cases. However, few studies have isolated Klebsiella ozaenae in a PTA. We present a case of a 29-year-old patient who was admitted as a case of a PTA. He underwent an incision and drainage of the right PTA in the operation room. A significant amount of purulent fluid was drained with a positive culture of K. ozaenae.
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  • 文章类型: Case Reports
    幽门螺杆菌,革兰氏阴性螺旋细菌,历史上主要与免疫功能低下患者的感染有关。最近,然而,已经认识到其在有免疫能力的个体中引起感染的潜力。我们报告了一个20多岁的男人报告与男人发生性关系的独特案例。他出现发烧和喉咙不适的症状,并被诊断为扁桃体周围脓肿。虽然A组链球菌的快速抗原检测呈阳性,并给予抗生素,抗生素治疗后第1天,扁桃体周围脓肿穿刺液显示存在C组链球菌.第五天,第一天的血培养检测到革兰氏阴性螺旋体,随后被鉴定为H.cinaedi。病人和他的男性伴侣进行了口交,提示潜在的传播途径。这很重要,因为H.cinaedi最初是从男男性行为者(MSM)的直肠培养物中发现的,通过口交提高咽部传播的可能性。在我们的病人身上,虽然H.cinaedi没有从扁桃体周围脓肿的抽吸中分离出来,它存在于血培养物中,并且缺乏其他潜在的菌血症来源,使得脓肿可能是感染的主要部位。该案例强调了将H.cinaedi视为免疫功能正常患者的潜在病原体的重要性,特别是在MSM的情况下。H.cinaedi通过口交传播的可能性及其在扁桃体周围脓肿发展中的作用,以前未报告的协会,需要进一步调查。
    Helicobacter cinaedi, a gram-negative spiral bacterium, has historically been associated with infections primarily in immunocompromised patients. Recently, however, its potential to cause infections in immunocompetent individuals has been recognized. We report a unique case of a man in his 20 s who reported having sex with men. He presented with symptoms of fever and throat discomfort and was diagnosed with a peritonsillar abscess. While the rapid antigen test for Group A Streptococcus was positive and antibiotics were administered, a puncture fluid from the peritonsillar abscess taken the day after antibiotic treatment revealed the presence of Group C Streptococcus. By the fifth day, the blood culture taken on the first day detected a gram-negative spirochete, which was subsequently identified H. cinaedi. The patient had engaged in oral sex with his male partner, suggesting a potential transmission route. This is significant as H. cinaedi was initially identified from rectal cultures in men who have sex with men (MSM), raising the possibility of pharyngeal transmission through oral sex. In our patient, although H. cinaedi was not isolated from the aspirate of the peritonsillar abscess, its presence in the blood culture and lack of other potential sources of bacteremia make the abscess a likely primary site of infection. This case highlights the importance of considering H. cinaedi as a potential pathogen in immunocompetent patients, particularly in cases of MSM. The potential for H. cinaedi transmission through oral sex and its role in the development of peritonsillar abscesses, a previously unreported association, requires further investigation.
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  • 文章类型: Case Reports
    本文描述了一例并发颅内并发症的多微生物弧菌溶血咽炎和鼻窦炎,并回顾了文献中的类似病例。
    一名21岁的有免疫能力的男性出现喉咙痛的症状,鼻漏,嗜睡,头痛,和皮疹。影像学显示鼻窦炎,鼻中隔前鼻窦炎,扁桃体周围脓肿形成,硬膜下积脓和脑炎。他接受了内窥镜鼻窦手术,开颅术用于清除硬膜下积脓和抗生素。微生物样本显示溶血曲霉的生长,链球菌。anginosus,和坏死梭菌。随后,他患上了脑脓肿,需要立体定向针引流。经过长时间的抗生素治疗,病人已出院,恢复良好。
    A.溶血是非链球菌性咽炎的罕见原因,可能与其他微生物一起发生,很少与严重的颅内并发症相关.在免疫活性宿主的复杂上呼吸道感染中,应考虑这种生物及其抗生素敏感性模式。青霉素类和大环内酯类抗生素是溶血链球菌治疗的主要手段。
    UNASSIGNED: This article describes a case of polymicrobial Arcanobacterium haemolyticum pharyngitis and sinusitis complicated by intracranial complications and reviews similar cases in the literature.
    UNASSIGNED: A 21-year-old immunocompetent male presented with symptoms of sore throat, rhinorrhoea, lethargy, headache, and rash. Imaging demonstrated sinusitis, pre-septal sinusitis, peritonsillar abscess formation, subdural empyema and cerebritis. He was managed with endoscopic sinus surgery, craniotomy for evacuation of subdural empyema and antibiotics. Microbiological samples demonstrated growth of A. haemolyticum, strep. anginosus, and fusobacterium necrophorum. He subsequently developed a cerebral abscess requiring stereotactic needle drainage. After a prolonged course of antibiotics, the patient was discharge and made a good recovery.
    UNASSIGNED: A. haemolyticum is an uncommon cause of non-streptococcal pharyngitis that may occur alongside other microorganisms and is rarely associated with severe intracranial complications. This organism and its antibiotic susceptibility patterns should be considered in complicated upper respiratory tract infections in immunocompetent hosts. Penicillins and macrolide antibiotics form the mainstay of therapy for A. haemolyticum.
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  • 文章类型: Journal Article
    为了描述可再现的设计和构造,低成本,扁桃体周围脓肿(PTA)切口和引流模拟器,并评估其对学员信心的影响。
    我们开发的2部分模拟器由一个带有固定,部分开口和模块化PTA模具。模具是通过将乳液和水的混合物注入塑料气泡中创建的,其次是有机硅固化。钕磁铁将硅胶脓肿包固定在人体模型的上颚。该模拟器在年度耳鼻咽喉科新兵训练计划中使用。在模拟器训练前后,使用自我评估Likert量表问卷评估参与者的信心。包括参加新兵训练营并同意完成评估的四年级医学生和大三(一年级和二年级)居民。
    三个医学生,17名PGY-1和10名PGY-2居民同意完成评估。所有受训者都同意该模型对学习技能有用。参与者的总体训练后信心李克特得分,特别是PGY-1居民,与他们训练前的得分相比显著提高(P<.001)。
    我们的模式为居民提供了一个负担得起的高效培训机会,以提高他们管理PTA的能力。这种方法,其简单而有效的设计和低生产成本,显示了在更大范围内的可扩展性的潜力。
    UNASSIGNED: To describe the design and construction of a reproducible, low-cost, peritonsillar abscess (PTA) incision and drainage simulator and assess its impact on trainees\' confidence.
    UNASSIGNED: The 2-part simulator we developed consisted of a manikin head with a fixed, partially open mouth and a modular PTA mold. The mold is created by injecting a lotion and water mixture into plastic bubbles, followed by silicone solidification. Neodymium magnets secure the silicone-abscess packet to the manikin\'s palate. The simulator was utilized during an academic otolaryngology residency training program Annual Otolaryngology Boot Camp. A self-assessment Likert scale questionnaire was used to evaluate participants\' confidence before and after simulator training. Fourth-year medical students and junior (first and second year) residents who participated in the boot camp and agreed to complete the evaluation were included.
    UNASSIGNED: Three medical students, 17 PGY-1, and 10 PGY-2 residents agreed to complete the evaluation. All trainees agreed the model was useful for learning skills. The overall post-training confidence Likert scores of participants, and PGY-1 residents in particular, significantly improved compared to their pre-training scores (P < .001).
    UNASSIGNED: Our model offers an affordable and efficient training opportunity for residents to enhance their competence in managing PTAs. This approach, with its simple yet effective design and low production cost, shows potential for scalability on a broader scale.
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  • 文章类型: Journal Article
    背景/简介:牙源性感染是颈深感染(DNI)的主要病因之一。然而,慢性牙周炎(CP)与DNI发病率之间的关系尚未研究。本研究旨在评估CP后DNI和扁桃体周围脓肿(PTA)的发生率。方法:采用2002-2019年韩国国家健康保险服务-国家样本队列。在研究I中,4585名PTA患者与19,340名对照I参与者相匹配。收集了1年的CP历史,采用条件逻辑回归分析PTA的CP比值比(OR)。在研究二,46,293名DNI患者和185,172名对照II参与者进行匹配。收集了1年的CP历史,并对DNI的CP的OR进行条件逻辑回归。次要分析是在人口统计学中进行的,社会经济,和合并症亚组。结果:在研究I中,CP病史与PTA的发生率无关(校正OR=1.28,95%置信区间[CI]=0.91~1.81).在研究二,有CP病史的参与者中DNI的发生率更高(校正OR=1.55,95%CI=1.41~1.71).CP病史与DNI之间的关系在年轻群体中更明显,男性,低收入,和农村居民。结论:在韩国普通人群中,CP的既往史与DNI的高发病率相关。CP患者需要对DNI的潜在风险进行管理。
    Background/Introduction: Odontogenic infection is one of the main etiologies of deep neck infection (DNI). However, the relationship between chronic periodontitis (CP) and the incidence of DNI has not been examined. This study aimed to evaluate the incidence of DNI and peritonsillar abscess (PTA) after CP. Methods: The Korean National Health Insurance Service-National Sample Cohort 2002-2019 was used. In Study I, 4585 PTA patients were matched with 19,340 control I participants. A previous history of CP for 1 year was collected, and the odds ratios (ORs) of CP for PTA were analyzed using conditional logistic regression. In Study II, 46,293 DNI patients and 185,172 control II participants were matched. A previous history of CP for 1 year was collected, and conditional logistic regression was conducted for the ORs of CP for DNI. Secondary analyses were conducted in demographic, socioeconomic, and comorbidity subgroups. Results: In Study I, a history of CP was not related to the incidence of PTA (adjusted OR = 1.28, 95% confidence interval [CI] = 0.91-1.81). In Study II, the incidence of DNI was greater in participants with a history of CP (adjusted OR = 1.55, 95% CI = 1.41-1.71). The relationship between CP history and DNI was greater in groups with young, male, low-income, and rural residents. Conclusions: A prior history of CP was associated with a high incidence of DNI in the general population of Korea. Patients with CP need to be managed for the potential risk of DNI.
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  • 文章类型: Case Reports
    Capnocytophagasputigena是革兰氏阴性兼性厌氧菌,嗜油细菌通常存在于人类口咽菌群中。这种机会性病原体可以引起广泛的感染,从菌血症到败血症流产.然而,这是非常罕见的一个病人出现扁桃体炎由于C。在这里,我们讨论演示文稿,医院课程,以及在急性髓细胞性白血病的背景下,患者经历与梭菌相关的扁桃体炎并发症的临床轨迹。此外,我们深入研究了这种特殊病原体的治疗方法和挑战。
    Capnocytophaga sputigena is a gram-negative facultatively anaerobic, capnophilic bacterium typically residing in the human oropharyngeal flora. This opportunistic pathogen can cause a wide range of infections, from bacteremia to septic abortion. However, it is exceedingly rare for a patient to present with tonsillitis due to C. sputigena. Herein, we discuss the presentation, hospital course, and clinical trajectory of a patient experiencing complications of tonsillitis related to C. sputigena in the context of acute myeloid leukemia. Additionally, we delve into the treatment approaches and challenges in managing this particular pathogen.
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  • 文章类型: Journal Article
    目的:扁桃体周围脓肿(PTA)是一种常见的病理。处理包括收集的排水,与概率抗生素治疗相关。引流脓液的细胞细菌学测试(CBT)的有用性存在争议。
    方法:对我院2013年至2020年接受PTA治疗的患者进行回顾性研究。主要目的是评估CBT在PTA管理中的有用性。次要目标是确定PTA发作所涉及的细菌学特征,并在概率基础上评估细菌对抗生素的耐药性。
    结果:该研究包括207名患者:70名门诊患者(33%)和137名住院患者(67%)。100%的患者实施了概率抗生素治疗。系统进行CBT,106例患者为阴性,40%的病例显示口咽菌群,50%的微生物菌群和10%的无菌样品。101例CBT阳性患者中,99%的细菌对青霉素敏感。所有患者均成功治疗。根据细菌学结果,入院时采用的概率抗生素治疗没有变化.
    结论:引流脓液的CBT对PTA的管理没有影响。因此,对于没有合并症且入院时没有严重迹象的患者,CBT是不必要的。
    OBJECTIVE: Peritonsillar abscess (PTA) is a frequent pathology. Treatment consists in drainage of the collection, associated to probabilistic antibiotic therapy. The usefulness of cytobacteriological testing (CBT) of the drainage pus is controversial.
    METHODS: A retrospective study of patients managed for PTA between 2013 and 2020 in our university hospital was performed. The main objective was to assess the usefulness of CBT in the management of PTA. The secondary objectives were to determine the bacteriological profile involved in the onset of PTA and to assess the rate of bacterial resistance to antibiotics prescribed on a probabilistic basis.
    RESULTS: The study included 207 patients: 70 outpatients (33%) and 137 inpatients (67%). Probabilistic antibiotic therapy was implemented in 100% of patients. CBT was performed systematically and was negative in 106 patients, revealing oropharyngeal flora in 40% of cases, polymicrobial flora in 50% and sterile samples in 10%. In the 101 patients with positive CBT, the bacteria isolated were penicillin-sensitive in 99%. All patients were successfully treated. In the light of the bacteriological results, no changes were made to the probabilistic antibiotic therapy introduced on admission.
    CONCLUSIONS: CBT on drainage pus had no impact on the management of PTA. CBT is therefore unnecessary in patients with no comorbidities and no signs of severity at admission.
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