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Abstract：
Background/Introduction: Odontogenic infection is one of the main etiologies of deep neck infection (DNI). However, the relationship between chronic periodontitis (CP) and the incidence of DNI has not been examined. This study aimed to evaluate the incidence of DNI and peritonsillar abscess (PTA) after CP. Methods: The Korean National Health Insurance Service-National Sample Cohort 2002-2019 was used. In Study I, 4585 PTA patients were matched with 19,340 control I participants. A previous history of CP for 1 year was collected, and the odds ratios (ORs) of CP for PTA were analyzed using conditional logistic regression. In Study II, 46,293 DNI patients and 185,172 control II participants were matched. A previous history of CP for 1 year was collected, and conditional logistic regression was conducted for the ORs of CP for DNI. Secondary analyses were conducted in demographic, socioeconomic, and comorbidity subgroups. Results: In Study I, a history of CP was not related to the incidence of PTA (adjusted OR = 1.28, 95% confidence interval [CI] = 0.91-1.81). In Study II, the incidence of DNI was greater in participants with a history of CP (adjusted OR = 1.55, 95% CI = 1.41-1.71). The relationship between CP history and DNI was greater in groups with young, male, low-income, and rural residents. Conclusions: A prior history of CP was associated with a high incidence of DNI in the general population of Korea. Patients with CP need to be managed for the potential risk of DNI.
摘要：
背景/简介：牙源性感染是颈深感染（DNI）的主要病因之一。然而,慢性牙周炎（CP）与DNI发病率之间的关系尚未研究。本研究旨在评估CP后DNI和扁桃体周围脓肿（PTA）的发生率。方法:采用2002-2019年韩国国家健康保险服务-国家样本队列。在研究I中,4585名PTA患者与19,340名对照I参与者相匹配。收集了1年的CP历史，采用条件逻辑回归分析PTA的CP比值比(OR)。在研究二,46,293名DNI患者和185,172名对照II参与者进行匹配。收集了1年的CP历史，并对DNI的CP的OR进行条件逻辑回归。次要分析是在人口统计学中进行的，社会经济,和合并症亚组。结果：在研究I中，CP病史与PTA的发生率无关(校正OR=1.28,95%置信区间[CI]=0.91~1.81).在研究二,有CP病史的参与者中DNI的发生率更高(校正OR=1.55,95%CI=1.41~1.71).CP病史与DNI之间的关系在年轻群体中更明显，男性,低收入,和农村居民。结论：在韩国普通人群中，CP的既往史与DNI的高发病率相关。CP患者需要对DNI的潜在风险进行管理。
