关键词: Arcanobacterium haemolyticum Cerebral abscess Complicated bacteraemia Peritonsillar abscess Sinusitis Systemic infection

来  源:   DOI:10.1016/j.idcr.2024.e01960   PDF(Pubmed)

Abstract:
UNASSIGNED: This article describes a case of polymicrobial Arcanobacterium haemolyticum pharyngitis and sinusitis complicated by intracranial complications and reviews similar cases in the literature.
UNASSIGNED: A 21-year-old immunocompetent male presented with symptoms of sore throat, rhinorrhoea, lethargy, headache, and rash. Imaging demonstrated sinusitis, pre-septal sinusitis, peritonsillar abscess formation, subdural empyema and cerebritis. He was managed with endoscopic sinus surgery, craniotomy for evacuation of subdural empyema and antibiotics. Microbiological samples demonstrated growth of A. haemolyticum, strep. anginosus, and fusobacterium necrophorum. He subsequently developed a cerebral abscess requiring stereotactic needle drainage. After a prolonged course of antibiotics, the patient was discharge and made a good recovery.
UNASSIGNED: A. haemolyticum is an uncommon cause of non-streptococcal pharyngitis that may occur alongside other microorganisms and is rarely associated with severe intracranial complications. This organism and its antibiotic susceptibility patterns should be considered in complicated upper respiratory tract infections in immunocompetent hosts. Penicillins and macrolide antibiotics form the mainstay of therapy for A. haemolyticum.
摘要:
本文描述了一例并发颅内并发症的多微生物弧菌溶血咽炎和鼻窦炎,并回顾了文献中的类似病例。
一名21岁的有免疫能力的男性出现喉咙痛的症状,鼻漏,嗜睡,头痛,和皮疹。影像学显示鼻窦炎,鼻中隔前鼻窦炎,扁桃体周围脓肿形成,硬膜下积脓和脑炎。他接受了内窥镜鼻窦手术,开颅术用于清除硬膜下积脓和抗生素。微生物样本显示溶血曲霉的生长,链球菌。anginosus,和坏死梭菌。随后,他患上了脑脓肿,需要立体定向针引流。经过长时间的抗生素治疗,病人已出院,恢复良好。
A.溶血是非链球菌性咽炎的罕见原因,可能与其他微生物一起发生,很少与严重的颅内并发症相关.在免疫活性宿主的复杂上呼吸道感染中,应考虑这种生物及其抗生素敏感性模式。青霉素类和大环内酯类抗生素是溶血链球菌治疗的主要手段。
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