Orthopaedic

骨科
  • 文章类型: Journal Article
    方法:回顾性图表回顾。
    目的:通常通过开放或微创(MI)技术进行经椎间孔腰椎椎间融合术(TLIF)。用于基于家庭的治疗计划的移动应用已经越来越受欢迎。这项研究的目的是(1)比较患者报告的结果指标(PROMs)在使用基于移动的康复计划中最合规和最不合规的术后患者之间,(2)比较开放队列与MI-TLIF队列之间的PROM,(3)量化家庭康复计划的总体合规率。
    方法:进行回顾性图表回顾。患者被自动纳入康复计划。收集患者报告的结果测量信息系统(PROMIS)和Oswestry残疾指数(ODI)评分。将患者分为两个研究组。依从率计算为术前阶段和最终随访的活跃参与者人数之间的差异。
    结果:纳入220例患者。平均随访时间为23.2个月。无论患者的依从性如何,(Δ)PROMIS评分(P=0.261)或ΔODI评分(P=0.690)的变化均无差异。开放与MI-TLIF技术之间的结局评分无差异,按下载依从性分层(下载,DL+;没有下载,DL-)和电话提醒合规性(设置提醒、R+;未设置提醒,R-)术后。两个队列在最终随访中都显示出超过最小临床重要差异的临床改善。在最终的术后随访中,患者的总体依从性为71%。
    结论:尽管长期依从性高,受欢迎程度不断提高,基于家庭的术后康复计划的移动应用程序在接受TLIF的患者中的临床实用性较低.
    METHODS: Retrospective chart review.
    OBJECTIVE: Transforaminal lumbar interbody fusion (TLIF) via open or minimally invasive (MI) techniques is commonly performed. Mobile applications for home-based therapy programs have grown in popularity. The purpose of this study was to (1) compare patient-reported outcome measures (PROMs) between postoperative patients who were the most and least compliant in using the mobile-based rehabilitation programs, (2) compare PROMs between open vs MI-TLIF cohorts, and (3) quantify overall compliance rates of home-based rehabilitation programs.
    METHODS: A retrospective chart review was performed. Patients were automatically enrolled in the rehabilitation program. Patient-Reported Outcomes Measurement Information System (PROMIS) and Oswestry Disability Index (ODI) scores were collected. Patients were separated into two study groups. Compliance rate was calculated as the difference between the number of active participants at the preoperative phase and final follow-up.
    RESULTS: 220 patients were included. Average follow-up time was 23.2 months. No difference was found in the change in (∆) PROMIS scores (P = 0.261) or ∆ODI scores (P = 0.690) regardless of patient compliance. No difference was found in outcome scores between open vs MI-TLIF techniques stratified by download compliance (downloaded, DL+; did not download, DL-) and phone reminder compliance (set reminder, R+; did not set reminder, R-) postoperatively. Both cohorts demonstrated clinical improvement exceeding minimal clinically important difference at final follow-up. Overall patient compliance was 71% at final postoperative follow up.
    CONCLUSIONS: Despite high long-term compliance and rising popularity, mobile applications for home-based postoperative rehabilitation programs have low clinical utility in patients undergoing TLIF.
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  • 文章类型: Journal Article
    背景:下躯干骨折是老年人最常见的骨折之一。超级老年人(即,那些80岁及以上的人)代表了越来越多的人口,特别容易发生这些骨折。文献中没有完全描述超老年人群下躯干骨折的当代流行病学。
    方法:这项描述性流行病学研究使用了国家电子伤害监测系统(NEISS)来检查下躯干骨折的发生率和最新趋势(即,髋部骨折,骨盆,和腰椎)发生在2011年至2020年美国(US)的超老年人中。Annual,总的来说,和年龄/性别特异性发病率(IRs)进行分析。计算了年平均百分比变化(AAPC)估计值,以表明年伤害率趋势的幅度/方向。
    结果:在10年的研究期间,估计N=1,226,160名超老年患者下躯干骨折,总体IR为100.2/10,000人年风险(PYR)。髋部骨折占病例比例最大(IR=71.7PYR),其次是腰椎骨折(IR=14.7),骨盆骨折(IR=14.3)。超老年女性(IR=121.5PYR)下躯干骨折发生率明显高于男性(IR=65.7PYR)。九十岁和百岁老人的下躯干骨折发生率明显高于八十岁老人。考虑到人口增长,在研究期间,超老年患者的下躯干骨折的年发病率显着增加,从2011年的86.7PYR增加到2020年的107.2PYR(AAPC=2.7,p<0.001)。骨盆(AAPC=5.8)和腰椎(AAPC=6.9)骨折的年发病率均显着高于髋部骨折(AAPC=1.4)。
    结论:这项研究表明,在2011年至2020年的最近十年中,美国最古老的患者(80岁以上)中,下躯干骨折的年发病率显着增加,尤其是骨盆和腰椎骨折变得越来越普遍。发病率的增加凸显了未来研究的必要性,旨在优化这一脆弱和不断增长的人群的结果和生活质量。
    BACKGROUND: Fractures of the lower trunk are among the most common fractures occurring in the elderly. Super elderly individuals (i.e., those 80 years of age and older) represent a growing segment of the population and are especially prone to these fractures. The contemporary epidemiology of lower trunk fractures in the super elderly population is incompletely described in the literature.
    METHODS: This descriptive epidemiology study used the National Electronic Injury Surveillance System (NEISS) to examine the incidence and recent trends of lower trunk fractures (i.e., fractures of the hip, pelvis, and lumbar spine) occurring among super elderly individuals in the United States (US) from 2011 to 2020. Annual, overall, and age-/sex-specific incidence rates (IRs) were analyzed. Average annual percent change (AAPC) estimates were calculated to indicate the magnitude/direction of trends in annual injury rates.
    RESULTS: An estimated N=1,226,160 super elderly patients sustained lower trunk fractures over the 10-year study period for an overall IR of 100.2 per 10,000 person-years at-risk (PYR). Hip fractures accounted for the largest percentage of cases (IR=71.7 PYR), followed by lumbar spine fractures (IR=14.7), and pelvic fractures (IR=14.3). The incidence of lower trunk fractures among super elderly females (IR=121.5 PYR) was significantly greater than that of males (IR=65.7 PYR). The incidence of lower trunk fractures among nonagenarians and centenarians was significantly higher than that of octogenarians. Accounting for population growth yielded a significantly increasing annual incidence of lower trunk fractures in super elderly patients over the study period from 86.7 PYR in 2011 to 107.2 PYR in 2020 (AAPC=2.7, p<0.001). The annual incidence of both pelvic (AAPC=5.8) and lumbar spine (AAPC=6.9) fractures increased at a significantly higher rate than that of hip fractures (AAPC=1.4).
    CONCLUSIONS: This study suggests that the annual incidence of lower trunk fractures in the oldest cohort of patients in the US (80+ years of age) increased significantly during the recent decade from 2011 to 2020, with pelvic and lumbar fractures in particular becoming increasingly common. Increased incidence rates highlight the need for future research aimed at optimizing outcomes and quality of life in this frail and ever-growing segment of the population.
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  • 文章类型: Case Reports
    镰状细胞病通常导致髋关节的缺血性坏死(AVN),导致关节疼痛和活动范围受限。在传统治疗如全髋关节置换术或核心减压可能不够的情况下,Girdlestone程序,涉及股骨头的切除,被考虑。这个案例研究集中在一名19岁的男性护理学生患有镰状细胞病,他在16岁时接受了Girdlestone手术,寻求缓解髋部疼痛和活动受限。然而,该过程导致腿长差异和髋关节功能降低。随后的全髋关节置换术成功地将之前的手术转变为稳定的关节,改善患者的活动范围和消除疼痛。综合手术方法,包括软组织释放和术后康复,显著提高了患者的生活质量,强调全髋关节置换术作为Girdlestone手术后的高级干预措施的重要性。
    Sickle cell disease often leads to avascular necrosis (AVN) of the hip joint, resulting in joint pain and restricted range of motion. In cases where traditional treatments like total hip arthroplasty or core decompression may not suffice, the Girdlestone procedure, involving the resection of the femoral head, is considered. This case study centers on a 19-year-old male nursing student with sickle cell disease who underwent a Girdlestone procedure at 16 years of age, seeking relief from hip pain and limited mobility. However, the procedure led to leg length discrepancy and reduced hip function. Subsequent total hip arthroplasty successfully converted the prior procedure into a stable joint, improving the patient\'s range of motion and eliminating pain. The comprehensive surgical approach, including soft tissue releases and postoperative rehabilitation, significantly enhanced the patient\'s quality of life, emphasizing the importance of total hip arthroplasty as a superior intervention post-Girdlestone procedure.
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  • 文章类型: Journal Article
    马来西亚骨科杂志(MOJ)(ISSN1985-2533/2232-111X)是马来西亚骨科协会(MOA)和东盟骨科协会(AOA)的官方出版物。2007年5月,农业部出版了第一期独立发行的司法部,目的是传播新知识和提供骨科方面的最新资料,创伤和肌肉骨骼研究。从那以后,MOJ大幅增长,在众多数据库中实现索引,并于2022年在Scopus数据库中获得第二四分位数(Q2)排名。此文献计量分析旨在探讨在MOJ发表的文章的趋势和分布。
    MOJ的文献计量数据是从SCOPUS数据库中提取的,涵盖从索引到2022年的年份。信息,如作者,国家,文档类型,作者的关键词,引文,和其他参数是使用RStudio软件中的bibliometrix软件包提取的。然后使用相同的软件将数据呈现在表格和说明性图表中。
    在研究期间,共从Scopus数据库检索到305篇文章。三分之二的文章是原创文章和评论文章。一篇文章引用次数最多的是56篇,MOJ的前十篇文章是由来自七个不同国家的研究人员撰写的,突出期刊的多样性。尽管收到了各国提交的材料,不同国家的作者之间的合作很少。关键词如“covid-19”和“大流行”在作者关键词部分占主导地位,因为在研究期间,一生中只有一次的COVID-19,导致与此问题有关的许多出版物。
    此文献计量分析回顾了Scopus数据库中索引的所有文章,并提供了对贡献者信息和骨科研究趋势的见解。通过确定国家之间缺乏合作,希望这一分析能激励更多的骨科医生和研究人员合作,制作高质量的出版物。
    UNASSIGNED: The Malaysian Orthopaedic Journal (MOJ) (ISSN 1985-2533 / 2232-111X) is the official publication of the Malaysian Orthopaedic Association (MOA) and the ASEAN Orthopaedic Association (AOA). In May 2007, MOA published the first standalone issue of MOJ with the aim of disseminating new knowledge and providing updates in orthopaedics, trauma and musculoskeletal research. Since then, MOJ has grown significantly, achieving indexing in numerous databases and attaining a 2nd Quartile (Q2) rank in the Scopus database in 2022. This bibliometric analysis aims to explore the trends and distribution of articles published in MOJ.
    UNASSIGNED: Bibliometric data for MOJ was extracted from the SCOPUS database, covering the years from its indexing to 2022. Information such as authors, country, document type, author\'s keywords, citations, and other parameters were extracted using the bibliometrix package in the R Studio software. The data were then presented in tables and illustrative graphs using the same software.
    UNASSIGNED: A total of 305 articles were retrieved from the Scopus database during the study period. Two-thirds of the articles were original articles and review articles. The highest number of citations received by an article is 56, and top ten articles in MOJ were authored by researchers from seven different countries, highlighting the journal\'s diversity. Despite receiving submissions from various countries, there is minimal collaboration between authors of different countries. Keywords such as \"covid-19\" and \"pandemic\" dominate the authors\' keyword section due to the once-in-a-life-time COVID-19 which during the study period, resulting in numerous publications related to this issue.
    UNASSIGNED: This bibliometric analysis reviews all the articles indexed in the Scopus database and provides insight into the contributors\' information and the trends in orthopaedic research. By identifying the lack of collaboration between countries, it is hoped that this analysis can inspire more orthopaedic surgeons and researchers to collaborate and produce high-quality publications.
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  • 文章类型: Journal Article
    背景:随着对全膝关节置换术(TKA)的需求升级,90天再入院已成为当前基于价值的医疗保健系统的紧迫临床和经济问题。因此,医疗保健提供者一直专注于估计再入院患者的风险水平;然而,尚不清楚特定因素是否与不同类型的并发症相关(即,医疗或骨科相关)导致再入院。因此,本研究旨在:(1)确定总体,与医疗有关的,和骨科相关的90天再入院率;(2)建立风险因素的预测模型,影响总体,与医疗有关的,和骨科相关的TKA术后90天再入院。
    方法:纳入了2016年至2020年在美国大型三级学术中心进行的原发性单侧TKAs的前瞻性队列(n=10,521例患者)。计划外的再入院进行单独审查,以确定其主要原因,无论是医疗还是骨科。骨科相关的再入院是影响关节的特定并发症,假肢,或手术伤口。医疗再入院是由于需要医疗管理的任何其他原因。使用多变量逻辑回归模型来调查预先指定的危险因素与90天再入院之间的关联。以及医疗/骨科相关的独立再入院。
    结果:总体而言,90日再入院率为6.7%(n=704).这些再入院的82%以上是由于医疗相关原因(n=580),其余18%为骨科相关(n=124)再入院。90天再入院模型的AUC为0.68(95%CI[置信区间]:0.67至0.70)。性,吸烟,停留时间(LOS)出院处置(DD)与骨科再入院有关,而年龄,性别,种族,Charlson合并症指数(CCI),保险,手术日,阿片类药物过量风险(NARX)评分,LOS,和DD与医学相关的90天再入院相关.
    结论:TKA后医疗相关的再入院比骨科相关的再入院更为普遍。通过成功构建和验证多个90天再入院预测模型,我们强调了医疗和骨科相关再入院的不同风险特征.这强调了细微差别的必要性,针对患者的风险分层和预防措施。
    BACKGROUND: As the demand for total knee arthroplasty (TKA) escalates, 90-day readmissions have emerged as a pressing clinical and economic concern for the current value-based health care system. Consequently, health care providers have focused on estimating the risk levels of readmitted patients; however, it is unknown if specific factors are associated with different types of complications (ie, medical or orthopaedic-related) that lead to readmissions. Therefore, this study aimed to (1) determine the overall, medical-related, and orthopaedic-related 90-day readmission rate and (2) develop a predictive model for risk factors affecting overall, medical-related, and orthopaedic-related 90-day readmissions following TKA.
    METHODS: A prospective cohort of primary unilateral TKAs performed at a large tertiary academic center in the United States from 2016 to 2020 was included (n = 10,521 patients). Unplanned readmissions were reviewed individually to determine their primary cause, either medical or orthopaedic-related. Orthopaedic-related readmissions were specific complications affecting the joint, prosthesis, or surgical wound. Medical readmissions were due to any other cause requiring medical management. Multivariable logistic regression models were used to investigate associations between prespecified risk factors and 90-day readmissions, as well as medical and orthopaedic-related readmissions independently.
    RESULTS: Overall, the rate of 90-day readmissions was 6.7% (n = 704). Over 82% of these readmissions were due to medical-related causes (n = 580), with the remaining 18% being orthopaedic-related (n = 124) readmissions. The area under the curve for the 90-day readmission model was 0.68 (95% confidence interval: 0.67 to 0.70). Sex, smoking, length of stay, and discharge disposition were associated with orthopaedic readmission, while age, sex, race, the Charlson Comorbidity Index, insurance, surgery day, opioid overdose risk score, length of stay, and discharge disposition were associated with medical-related 90-day readmissions.
    CONCLUSIONS: Medical-related readmissions after TKA are more prevalent than orthopaedic-related readmissions. Through successfully constructing and validating multiple 90-day readmission predictive models, we highlight the distinct risk profiles for medical and orthopaedic-related readmissions. This emphasizes the necessity for nuanced, patient-specific risk stratification and preventive measures.
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  • 文章类型: Journal Article
    本文旨在概述当前的实践,并研究骨科创伤出血的现代管理方面有希望的新进展。几十年来,许多院前和围手术期出血控制策略和技术已被临床医生使用。然而,我们对这些做法的理解和利用仍在不断完善和优化。本文特别关注与创伤中的复苏和凝血相关的问题。我们研究了导致创伤患者凝血功能障碍的复杂机制,以及氨甲环酸在限制失血方面的转化作用。我们还探索了一些新兴技术,如血管内干预和凝块稳定敷料和设备,这些技术可能会对未来产生重大影响。
    This paper aims to outline current practices and examine promising new advancements in the modern management of haemorrhage in orthopaedic trauma. Many prehospital and perioperative haemorrhage control strategies and techniques have been available to clinicians for multiple decades, yet our understanding and utilisation of these practices continues to be refined and optimised. There is a particular focus in this article on issues related to resuscitation and coagulation in trauma. We examine the complex mechanisms that lead to coagulopathy in trauma patients as well as the transformative effect tranexamic acid has had in limiting blood loss. We also explore some emerging technologies such as endovascular interventions and clot-stabilising dressings and devices that are likely to have a significant impact going forward.
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  • 文章类型: Journal Article
    目的:评估骨科患者实施预防意外围手术期体温过低指南的障碍和促进因素。
    方法:系统评价。
    方法:九个数据库:PubMed,Embase,CINAHL,科克伦中部,PsycINFO,ProQuest论文和论文,Scopus,WebofScience和旅行临床证据数据库。
    方法:筛选了2008年1月至2022年7月以英文发表的主要研究。研究选择,质量评估,数据提取由研究者独立完成。使用实施研究综合框架提取数据,并将其映射到实施变更战略的专家建议。
    结果:本综述纳入了87项研究。最常报告的障碍和促进者与证据强度有关,相对优势,实施围手术期低温预防指南的成本。ERIC的四大战略是:确定和准备冠军;举办教育会议;评估准备情况并确定障碍和促进者;并通知当地舆论领袖。
    结论:本综述提供了关于骨科手术患者围手术期低体温障碍和促进因素的综合证据。
    我们的工作提供了理论指导策略,以促进实施围手术期低温预防,以帮助护士照顾骨科手术患者。
    结论:研究结果为专业人员提供护理骨科手术患者的理论参考策略,以改善围手术期低温预防。减少围手术期低温将改善骨科手术患者的预后。
    根据2020年系统评价和荟萃分析的首选报告项目进行报告。
    由于研究设计,没有进行患者或公众咨询。
    OBJECTIVE: To assess barriers and facilitators to the implementation of guidelines for the prevention of inadvertent perioperative hypothermia in orthopaedic patients.
    METHODS: Systematic review.
    METHODS: Nine databases: PubMed, Embase, CINAHL, Cochrane CENTRAL, PsycINFO, ProQuest Dissertations and Theses, Scopus, Web of Science and Trip Clinical Evidence Database.
    METHODS: Primary studies published in English between January 2008 to July 2022 were screened. Study selection, quality assessment, and data extraction were completed independently by researchers. Data were extracted using the Consolidated Framework for Implementation Research and mapped to the Expert Recommendations for Implementing Change strategies.
    RESULTS: Eighty-seven studies were included in the review. The most frequently reported barriers and facilitators related to evidence strength, relative advantage, and cost of implementing perioperative hypothermia prevention guidelines. The top four ERIC strategies were: Identify and prepare champions; Conduct educational meetings; Assess for readiness and identify barriers and facilitators; and Inform local opinion leaders.
    CONCLUSIONS: This review provides synthesized evidence regarding barriers and facilitators to perioperative hypothermia guidelines for patients undergoing orthopaedic surgery.
    UNASSIGNED: Our work provides theory guided strategies to promote implementation of perioperative hypothermia prevention to assist nurses caring for patients undergoing orthopaedic surgery.
    CONCLUSIONS: Findings provide professionals caring for patients undergoing orthopaedic surgery with theory-informed strategies to improve perioperative hypothermia prevention. Reducing perioperative hypothermia will improve outcomes for patients undergoing orthopaedic surgery.
    UNASSIGNED: The review is reported according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses 2020.
    UNASSIGNED: Due to the study design, no patient or public consultation took place.
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  • 文章类型: Journal Article
    尼日利亚有一个相对较大的科学界,在非洲国家中产生了足够的研究成果。没有多少研究分析了尼日利亚和非洲骨科和运动医学的研究成果。因此,我们旨在分析尼日利亚和非洲在骨科和运动医学方面的研究成果。
    我们使用了ScimagoJournal&CountryRank网站上的SCOPUS数据。它使我们能够绘制各种期刊指标进行研究。
    在1996年至2022年之间,尼日利亚骨科和运动医学研究出版物从1996年的4篇增加到2022年的39篇(增长了10倍),但总体上占世界第62篇,占同期出版物的0.07%。在同一时期,非洲发表了8297篇骨科和运动医学论文,仅占该领域全球出版物的1.24%。
    尼日利亚的骨科和运动医学研究产出低,整个非洲大陆。然而,来自非洲的出版物有所增加。
    UNASSIGNED: Nigeria has a relatively large scientific community that produces an adequate research output among African countries. Not many studies have analysed the research output in orthopaedics and sports medicine from Nigeria and Africa. Hence, we aimed to analyze the research output in orthopaedics and sports medicine from Nigeria and Africa.
    UNASSIGNED: We used the SCOPUS data from the Scimago Journal & Country Rank website. It allows us to draw various journal metrics for research.
    UNASSIGNED: Between 1996 and 2022, Nigerian research publications in orthopaedics and sports medicine had grown from 4 in 1996 to 39 in 2022 (a 10-fold growth) but overall is 62nd in the world representing 0.07% of publications in the period. In the same period, Africa published 8297 papers in orthopaedics and sports medicine representing only 1.24% of the global publications in this field.
    UNASSIGNED: There is low research output in Orthopaedics and Sports Medicine from Nigeria and, the whole African continent. However, there has been a growth in the publications from Africa.
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  • 文章类型: Journal Article
    背景:在马的实践中,通常使用二氧化硅喷雾管(SST)来运输滑液样品。它们促进样品的凝结。该研究的目的是评估SST对细菌培养的影响。
    方法:研究分为两部分:无菌盐水(A部分)和滑液(B部分)。使用了与马滑膜败血症相关的四种常见细菌:化脓性链球菌,大肠杆菌,金黄色葡萄球菌和耐甲氧西林金黄色葡萄球菌(MRSA)。使用了三个收集管:STT,普通(无添加剂)和脑和心脏输液(BHI)肉汤。细菌在马血琼脂平板中培养48小时。结果变量为阴性培养物,阳性培养物和菌落形成单位总数(CFU)。使用Mann-WhitneyU检验进行统计分析,并且显著性设定为p<0.05。
    结果:琼脂平板读数总数为1557(779生理盐水;778滑液)。总阴性培养物在盐水中为25/779,在滑液中为3/778。在肉汤中,所有细菌的生理盐水和滑液均在8小时后达到最大生长CFU。在SST中,产脓菌和大肠杆菌在4小时后与普通或肉汤相比,产生的CFU数量显着降低,而金黄色葡萄球菌(美国典型培养物保藏中心[ATCC]和MRSA)仅在24小时后。
    结论:含二氧化硅管减少细菌增殖,而BHI肉汤的使用提供了样品中最高的细菌负荷。SST的使用可能对从临床病例获得的样品中的细菌增殖具有负面影响。
    BACKGROUND: Silica-sprayed tubes (SSTs) are often used to transport synovial fluid samples in equine practice. They promote the coagulation of the sample. The objective of the study is to evaluate the effect of SST on bacterial culture.
    METHODS: The study was divided into two parts: sterile saline (Part A) and synovial fluid (Part B). Four common bacteria associated with equine synovial sepsis were used: Streptococcus pyogenes, Escherichia coli, Staphylococcus aureus and methicillin-resistant S. aureus (MRSA). Three collection tubes were used: STT, plain (no-additives) and brain and heart infusion (BHI) broth. Bacteria were cultured in horse blood agar plates for 48 h. Outcome variables were negative culture, positive culture and total number of colony-forming units (CFUs). Statistical analysis was performed using Mann-Whitney U test, and significance was set at p < 0.05.
    RESULTS: The total number of agar plates read was 1557 (779 saline; 778 synovial fluid). Total negative cultures were 25/779 on saline and 3/778 on synovial fluid. In broth, maximum growth CFU was achieved after 8 h for both saline and synovial fluid for all bacteria. S. pyogenesand E. coli produced a significantly lower number of CFU when in SST compared to plain or broth after 4 h, whereas S. aureus (American Type Culture Collection [ATCC] and MRSA) only after 24 h.
    CONCLUSIONS: Silica-containing tubes reduced bacterial proliferation, whereas the use of a BHI broth provided the highest bacterial load in the sample. The use of SST may have a negative effect on bacterial proliferation in samples obtained from clinical cases.
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  • 文章类型: Journal Article
    许多患有膝关节骨关节炎(OA)疼痛的人要么没有准备好手术,要么可能永远不会成为手术候选人。尽管进行了最大的医疗管理,但对于疼痛患者来说,生殖器动脉栓塞(GAE)是一种新的治疗方法。它历来用于治疗全膝关节置换术后复发性自发性关节积血,但较新的研究显示在治疗关节置换术前膝关节OA方面具有积极作用.这篇评论的目的是从对计算机化数据库和相关期刊的搜索中总结当前和相关文献,并分析其结果。包括的研究表明,GAE在治疗那些已经精疲力竭至少3个月的保守治疗的人的轻度至中度OA膝关节疼痛方面具有有希望的结果。大多数研究表明VAS疼痛和PROM评分(包括KOOS,和/或WOMAC)。在长达两年的随访中,副作用最小,其中大多数是自我解决的。本文为执行GAE提供了一种简洁的通用程序技术,以及比较和对比可能使用的不同栓塞剂。GAE在轻度至中度OA膝关节疼痛的治疗中显示出有希望的结果。在未来,需要进行更大量的研究来确定有效性,合适的候选人,和其他潜在的不利影响。
    Many people with pain from osteoarthritis (OA) of the knee are either not ready for surgery or may never be surgical candidates. Genicular artery embolization (GAE) is a new proposed management for those with pain despite maximum medical management. It has historically been used to manage recurrent spontaneous haemarthrosis following total knee replacement, but newer studies are showing a positive effect in managing pre-arthroplasty knee OA. The goal of this review is to summarise current and relevant literature from searches of computerised databases and relevant journals, and analyse their results. Studies included show that GAE has promising outcomes in managing mild to moderate OA knee pain in those who have exhausted at least 3 months of conservative therapy. Most studies show improvements in VAS pain and PROM scores (including KOOS, and/or WOMAC). Minimal adverse effects have been associated in up to two years of follow up, the majority of which are self-resolving. The article précises a concise general procedural technique for performing GAE, as well as comparing and contrasting different embolic agents that may be utilised. GAE shows promising outcomes in management of mild to moderate OA knee pain. In the future, there will need to be higher volume studies to determine effectiveness, suitable candidates, and other potential adverse effects.
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