PDF(Pubmed)
Abstract：
This paper aims to outline current practices and examine promising new advancements in the modern management of haemorrhage in orthopaedic trauma. Many prehospital and perioperative haemorrhage control strategies and techniques have been available to clinicians for multiple decades, yet our understanding and utilisation of these practices continues to be refined and optimised. There is a particular focus in this article on issues related to resuscitation and coagulation in trauma. We examine the complex mechanisms that lead to coagulopathy in trauma patients as well as the transformative effect tranexamic acid has had in limiting blood loss. We also explore some emerging technologies such as endovascular interventions and clot-stabilising dressings and devices that are likely to have a significant impact going forward.
摘要：
本文旨在概述当前的实践，并研究骨科创伤出血的现代管理方面有希望的新进展。几十年来，许多院前和围手术期出血控制策略和技术已被临床医生使用。然而，我们对这些做法的理解和利用仍在不断完善和优化。本文特别关注与创伤中的复苏和凝血相关的问题。我们研究了导致创伤患者凝血功能障碍的复杂机制，以及氨甲环酸在限制失血方面的转化作用。我们还探索了一些新兴技术，如血管内干预和凝块稳定敷料和设备，这些技术可能会对未来产生重大影响。
