■近年来,克服肿瘤免疫抑制机制的新治疗选择在皮肤黑色素瘤的治疗中是有效的。这些方法也已应用于眼部黑素瘤。本研究旨在从文献计量学的角度介绍眼部黑色素瘤免疫治疗的现状和研究热点,探索眼部恶性黑色素瘤免疫治疗研究领域。
■在这项研究中,我们选择了WebofScience核心收藏数据库(WoSCC)和Pubmed来搜索与眼部黑色素瘤免疫治疗相关的文献.使用VOSviewer,CiteSpace,R包“参考书”,\"和文献计量在线平台,通过文献计量网络的构建和可视化,国家/地区,机构,journal,作者,和关键词进行了分析,以预测与眼部黑色素瘤和免疫治疗有关的研究的最新趋势。
■共纳入与眼部黑色素瘤免疫治疗相关的401篇论文和144篇综述。美国是该领域研究的主要驱动力,出版物数量排名第一,总引用次数,和H指数。德克萨斯大学系统是最活跃的机构,贡献最多的论文。Jager,Martine是最多产的作家,和Carvajal,理查德是最常被引用的作家。CANCERS是该领域发表最多的期刊,JCLINONCOL是被引用最多的期刊。除了眼部黑色素瘤和免疫疗法,最受欢迎的关键词是“葡萄膜黑色素瘤”和“靶向治疗”。根据关键字共现和突发分析,葡萄膜黑色素瘤,免疫疗法,黑色素瘤,转移,bap1tebentafusp,生物信息学,结膜黑色素瘤,免疫检查点抑制剂,ipilimumab,pembrolizumab,和其他研究主题似乎处于该领域研究的前沿,并有可能在未来继续成为研究热点。
■这是最近30年来首次全面绘制与眼部黑色素瘤和免疫治疗相关研究领域的知识结构和趋势的文献计量学研究。该研究结果全面总结并确定了学者研究与眼部黑色素瘤相关的免疫治疗的研究前沿。
UNASSIGNED: In recent years, new therapeutic options to overcome the mechanisms of tumor immune suppression be effective in the treatment of cutaneous melanoma. These approaches have also been applied in ocular melanoma. The aim of this study is to present the current status and research hotspots of immunotherapy for ocular melanoma from a bibliometric perspective and to explore the field of immunotherapy for malignant ocular melanoma research.
UNASSIGNED: In this study, the Web of Science Core Collection database (WoSCC) and Pubmed were selected to search the literature related to immunotherapy of ocular melanoma. Using VOSviewer, CiteSpace, the R package \"bibliometrix,\" and the bibliometric online platform through the construction and visualization of bibliometric networks, the country/region, institution, journal, author, and keywords were analyzed to predict the most recent trends in research pertaining to ocular melanoma and immunotherapy.
UNASSIGNED: A total of 401 papers and 144 reviews related to immunotherapy of ocular melanoma were included. The United States is the main driver of research in the field, ranking first in terms of the number of publications, total citations, and H-index. The UNIVERSITY OF TEXAS SYSTEM is the most active institution, contributing the most papers. Jager, Martine is the most prolific author, and Carvajal, Richard is the most frequently cited author. CANCERS is the most published journal in the field and J CLIN ONCOL is the most cited journal. In addition to ocular melanoma and immunotherapy, the most popular keywords were \"uveal melanoma\" and \"targeted therapy\". According to keyword co-occurrence and burst analysis, uveal melanoma, immunotherapy, melanoma, metastases, bap1, tebentafusp, bioinformatics, conjunctival melanoma, immune checkpoint inhibitors, ipilimumab, pembrolizumab, and other research topics appear to be at the forefront of this field\'s research and have the potential to remain a hot research topic in the future.
UNASSIGNED: This is the first bibliometric study in the last 30 years to comprehensively map the knowledge structure and trends in the field of research related to ocular melanoma and immunotherapy. The results comprehensively summarize and identify research frontiers for scholars studying immunotherapy associated with ocular melanoma.