Neurologists

神经学家
  • 文章类型: Journal Article
    多年来,周围神经病变的患病率有所增加,在过去的十年中,出现了用于管理多种神经病变的新治疗方法。在对ICHUSHI数据库进行文献检索后,我们观察到,最近关于周围神经病变的文献最常包括骨科专业的报道,其次是神经病学服务报告的研究。值得注意的是,在过去的十年中,神经科报告的研究数量有所增加。然而,大多数常见周围神经病变患者不去神经内科就诊。因此,有必要强调神经科医师在全面评估和管理神经肌肉疾病方面的作用。这可能导致神经学被确认为周围神经系统疾病的主要看门人。
    The prevalence of peripheral neuropathies has increased over the years, and novel treatments for management of several neuropathies have emerged over the past decade. Following a literature search of the ICHUSHI database, we observed that recent literature on peripheral neuropathy most frequently includes reports from the orthopedic specialty, followed by studies reported by the neurology service. Notably, the number of studies reported by the neurology departments has increased over the past decade. However, most patients with common peripheral neuropathies do not visit the neurology department. Therefore, it is necessary to highlight the role of neurologists for comprehensive evaluation and management of neuromuscular disorders. This may result in acknowledgement of neurology as the primary gatekeeper of peripheral neurological diseases.
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  • 文章类型: Journal Article
    确定急性再灌注治疗的适应症(静脉内重组组织纤溶酶原激活剂给药和机械血栓切除术)以及中风模拟物和变色龙的鉴定是有效中风治疗的重要组成部分。此外,神经科医师选择适当的药物和管理病人的一般情况。因此,基于神经症状学的神经科医生扎实的诊断技能和内科医生广泛的知识和洞察力在临床上发挥着关键作用。
    Determination of indications for acute reperfusion therapy (intravenous recombinant tissue plasminogen activator administration and mechanical thrombectomy) and identification of stroke mimics and chameleons are essential components of effective stroke treatment. Moreover, neurologists select the appropriate medications and manage the patient\'s general condition. Therefore, a neurologist\'s solid diagnostic skills based on neurological symptomatology and an internist\'s broad knowledge and insight play key roles clinically.
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  • 文章类型: Journal Article
    本杂志2013年9月号包含一篇题为“神经学家在痴呆症实践中的作用”的文章,其中我强调了神经学家对痴呆症护理的贡献。我强调了在包括全科医生和精神科医生在内的跨学科团队中积极领导的重要性。在实施《促进包容性社会的痴呆症基本法》和医学科学进步之后,比如引入抗阿尔茨海默氏症药物莱卡尼玛,预计神经科医师将在痴呆症管理中发挥更积极的作用,并且需要更多的专业技能.lecanemab的出现导致神经科医生更直接地参与痴呆症的实践,这导致了“新手”痴呆症专家的出现。然而,在日本,专门研究行为神经病学的神经学家的短缺仍然是一个重要的问题。在这一领域,普通神经科医生的教育不足加剧了这一挑战,因为痴呆症管理需要行为神经病学的深厚知识和技能。最重要和最紧迫的问题是迅速解决这种短缺。虽然神经学家参与痴呆症实践是由于引入了lecanemab,我真诚地期待神经学家从“新手”过渡到“真正的”痴呆症专家。我重申这一呼吁是对神经科医生的建议,强调需要发展成为该领域的真正专家。
    The September 2013 issue of this journal contains an article titled \"The Role of Neurologists in Dementia Practice\" in which I have highlighted the contributions of neurologists to dementia care. I have emphasized the importance of proactive leadership within interdisciplinary teams that include general practitioners and psychiatrists. Following the implementation of the Basic Act on Dementia to Promote an Inclusive Society and advances in medical science, such as introduction of the anti-Alzheimer drug lecanemab, neurologists are expected to play a more active role in dementia management and require more specialized skills. The emergence of lecanemab has led to more direct involvement of neurologists in dementia practice, which has resulted in the emergence of \"novice\" dementia specialists. However, a shortage of neurologists who specialize in behavioral neurology remains a significant concern in Japan. This challenge is compounded by the inadequate education of general neurologists in this domain, because dementia management requires deep knowledge and skills in behavioral neurology. The most important and urgent issue is to promptly address this shortage. Although neurologists\' involvement in dementia practice is attributable to the introduction of lecanemab, I sincerely look forward to neurologists transitioning from \"novice\" to \"real\" experts in dementia. I reiterate this call as a recommendation to fellow neurologists, emphasizing the need to evolve into true specialists in the field.
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  • 文章类型: Journal Article
    随着时间的推移,创新的神经病学药物进入美国医疗保健系统,神经学家应该考虑这些治疗的成本,除了他们的疗效,安全,和耐受性。要想做到这一点,需要了解处方药在美国的定价方式。药品定价过程与分销供应链和涉及的许多利益相关者有关。利益相关者包括药品制造商;批发商;药房;药房福利经理;付款人,包括健康保险公司;医院系统;神经科医生和其他临床医生;和患者。药品定价已成为焦点,因为2022年的《降低通货膨胀法案》在该计划的历史上首次为Medicare受益人设定了最高自付费用,并限制了一组MedicareD部分药物的药品价格上涨。本文介绍了美国药品分销供应链及其利益相关者,并介绍了关键的药品定价术语;还将讨论如何通常估计回扣的简要说明。最后,随着新的神经科门诊药物进入市场,药物的“价值”将通过成本效益术语及其对临床神经科医生的效用来描述。
    UNASSIGNED: As newer, innovative neurology drugs enter the US health care system, neurologists should consider the cost of these treatments in addition to their efficacy, safety, and tolerability. To do so thoughtfully requires an understanding of how prescription drugs are priced in the United States. The process of drug pricing is linked to the distribution supply chain and the many stakeholders involved. Stakeholders include pharmaceutical manufacturers; wholesalers; pharmacies; pharmacy benefit managers; payers, including health insurers; hospital systems; neurologists and other clinicians; and patients. Drug pricing has taken center stage as the Inflation Reduction Act of 2022 has set maximum out-of-pocket expenses for Medicare beneficiaries for the first time in the program\'s history and limits drug price increases for a select group of Medicare Part D drugs. This article describes the US drug distribution supply chain and its stakeholders and introduces key drug pricing terms; a brief description of how rebates are generally estimated will also be discussed. Finally, as newer neurology outpatient drugs enter the market, the \"value\" of drugs will be described through cost-effectiveness terminology and their utility for the clinical neurologist.
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  • 文章类型: Journal Article
    急性缺血性中风是小儿死亡和残疾的主要原因。适用于儿童的临床量表可以确保早期发现紧急急性缺血性中风治疗的候选人。成人快速动脉阻塞评估(RACE)量表,得分为5项(面神经麻痹0-2;手臂运动功能0-2;腿部运动功能0-2;头部/注视偏离0-1;失语或失认0-2),对检测大血管闭塞具有良好的敏感性和特异性。
    我们调整了先前验证的RACE量表作为儿科RACE量表用于儿童。这种适应的量表由院前/急诊室工作人员进行了测试,这些工作人员负责加泰罗尼亚小儿中风规范所涵盖的患者和儿童神经科医生,其与小儿国立卫生研究院中风量表的相关性以及评估者间的可靠性。
    这项研究包括50名儿童,18例确诊中风(7例急性缺血性中风和11例出血性中风)。院前/急诊工作人员和儿童神经科医师完全同意82%的患者和100%的头部/凝视偏差和失认症。在儿童神经学家的评估中,儿科RACE量表与儿科国立卫生研究院卒中量表密切相关(Spearmanρ,0.852;P<0.001)和院前/急诊工作人员(Spearmanρ,0.781;P<0.001)。大血管闭塞患者的中位儿科RACE评分明显较高(6.5;四分位距,6-7)比其他病因。
    儿科比赛,显示出良好的评分者间信度和与美国国立卫生研究院卒中量表的相关性,是检测儿科急性中风治疗候选药物的简单量表,专为院前和住院使用的非神经科医务人员。
    UNASSIGNED: Acute ischemic stroke is a leading cause of pediatric death and disability. A clinical scale adapted for children can ensure early detection of candidates for urgent acute ischemic stroke treatment. The Rapid Arterial Occlusion Evaluation (RACE) scale for adults, which scores 5 items (facial palsy 0-2; arm motor function 0-2; leg motor function 0-2; head/gaze deviation 0-1; and aphasia or agnosia 0-2), has good sensitivity and specificity in detecting large vessel occlusion.
    UNASSIGNED: We adapted the previously validated RACE scale for use in children as the Pediatric RACE scale. This adapted scale was tested by prehospital/emergency room staff attending to patients covered by the Catalan Pediatric Stroke Code and child neurologists for its correlation with the Pediatric National Institutes of Health Stroke Scale and for interrater reliability.
    UNASSIGNED: The study included 50 children, 18 with confirmed strokes (7 acute ischemic strokes and 11 hemorrhagic strokes). Prehospital/emergency staff and child neurologists agreed fully regarding 82% of patients and 100% regarding head/gaze deviation and agnosia. The Pediatric RACE scale correlated strongly with the Pediatric National Institutes of Health Stroke Scale in evaluations by child neurologists (Spearman ρ, 0.852; P<0.001) and prehospital/emergency staff (Spearman ρ, 0.781; P<0.001). The median Pediatric RACE score was significantly higher in patients with large vessel occlusion (6.5; interquartile range, 6-7) than with other etiologies.
    UNASSIGNED: Pediatric RACE, showing good interrater reliability and correlation with the Pediatric National Institutes of Health Stroke Scale, is a simple scale to detect candidates for pediatric acute stroke treatment, designed for both prehospital and in-hospital use by non-neurologist medical staff.
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  • 文章类型: English Abstract
    BACKGROUND: The demand for chat messaging apps for communication between physicians, therapists and patients is increasing. The expectations for this form of communication and uncertainties regarding introduction and use are heterogeneous.
    OBJECTIVE: The implementation of chat messengers in the care of patients with Parkinson\'s disease should be facilitated by recommendations regarding introduction and usage.
    METHODS: Semi-structured interviews with neurologists and physiotherapists were conducted to capture the expectations and needs regarding the use of chat messengers. From the data analysis, recommendations were derived.
    RESULTS: The expectations for technical functionality exceeded the chat messenger functions. This concerns, e.g., the connection of the chat messenger to the electronic patient file. There is a great deal of uncertainty, particularly when it comes to the applicable General Data Protection Regulations (GDPR). The recommendations relating to the use of chat messengers, data protection aspects, the design of such tools and methodological considerations can help to implement the tool as an additional communication channel.
    CONCLUSIONS: Practical recommendations regarding functionality, the use of chat messengers in everyday life and in relation to data protection are derived from the results. By improving knowledge, physicians and therapists can contribute to the successful establishment of chat messengers as an additional communication tool.
    UNASSIGNED: HINTERGRUND: Die Nachfrage nach Chat-Messengern für den Austausch zwischen Ärzten, Therapeuten und ihren Patienten steigt. Die Erwartungen an die Chat-Messenger und Unsicherheiten hinsichtlich Einführung und Nutzung sind heterogen.
    UNASSIGNED: Die Implementierung eines Chat-Messengers in die Parkinson-Versorgung soll durch die Formulierung einführungs- und anwendungsrelevanter Empfehlungen vereinfacht werden.
    METHODS: Semistrukturierte Interviews mit Neurologen und Physiotherapeuten wurden durchgeführt, um die Erwartungen an die Nutzung von Chat-Messengern zu erfassen, welche die Basis für die abgeleiteten Empfehlungen bildeten.
    UNASSIGNED: Die Erwartungen an die technische Funktionalität übersteigen die Funktionen von Chat-Messenger. Das betrifft z. B. die Anbindung des Chat-Messengers an die elektronische Patientenakte. Insbesondere auch bei den anzuwendenden Regelungen der Datenschutz-Grundverordnung (DSGVO) herrscht große Unsicherheit. Die Empfehlungen, die sich auf die Nutzung der Chat-Messenger, auf die Aspekte des Datenschutzes, die Gestaltung dieser Technologien und methodische Überlegungen beziehen, sollen bei der Implementierung des Tools als zusätzlichen Kommunikationskanal helfen.
    CONCLUSIONS: Aus den Ergebnissen leiten sich Empfehlungen zur Funktionalität, dem Umgang mit Chat-Messengern im Alltag und in Bezug zum Datenschutz ab. Durch Verbesserung der Kenntnisse bei den Gesundheitsberuflern und Beachtung dieser Handlungsanweisungen können Ärzte und Therapeuten zu einer erfolgreichen Etablierung des Chat-Messengers als zusätzliches Kommunikationstool beitragen.
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  • 文章类型: Journal Article
    隐性偏见与医疗职业中的性别差异有关,不仅会影响获得领导职位,还会影响早期的职业机会。我们旨在根据性别评估神经内科住院医师的评估是否存在差异。我们收集了居民提交的两个主要评估的公开可用等级和排名,一个在神经科住院医师计划的开始和结束时,国家委员会考试和神经病学考试,分别。国家委员会考试是一项多项选择的性别盲化评估,而神经病学检查是一种口头性别非盲法评估。我们发现,36.5%的女性和21.6%的男性在国家委员会考试排名的第一四分位数中,这反映了在通过性别盲化检查进行评估时,顶级分类之间的相似表示。另一方面,NE最高分类的男性百分比,性别非盲化评估,是女性的两倍多(37.8%对18.3%,p<0.05)。本研究的发现可能暗示,在葡萄牙神经科居民中,女性的职业发展可能存在差异,尽管性别之间的招聘似乎是平衡的。
    Implicit bias has been linked to gender disparities in medical careers, impacting not only access to leadership positions but also early career opportunities. We aimed to evaluate if there were differences in the assessment of Neurology residents according to gender. We collected publicly available grades and rankings of two major evaluations that residents are submitted to, one at the beginning and another at the end of the neurology residency program, the National Board Exam and neurology examination, respectively. The National Board Examination is a multiple-choice gender-blinded evaluation, while the neurology examination is an oral gender-unblinded evaluation. We found that 36.5% of women and 21.6% of men were in the first quartile of the National Board Examination ranking, which reflects a similar representation among top classifications when assessed through a gender-blinded examination. On the other hand, the percentage of men who were in the top classification of NE, a gender-unblinded evaluation, was more than twice as high compared to women (37.8% vs 18.3%, p < 0.05). The findings of the present study may imply that there could be a disparity in women\'s career progression among neurology residents in Portugal, although the recruitment seems balanced between genders.
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  • 文章类型: Journal Article
    暂无摘要。
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  • 文章类型: Journal Article
    目的:现在越来越多的Duchenne型肌营养不良症(DMD)患者可以获得改善的护理标准和疾病改善治疗,这改善了DMD的临床病程,并延长了30岁以上的预期寿命。青少年DMD患者的一个关键问题是从以医学为导向的医疗保健过渡到以成人为导向的医疗保健。患有DMD的青少年和成年人有独特但高度复杂的医疗保健需求,与长期使用类固醇相关。骨科,呼吸,心脏,心理,和胃肠道问题意味着需要一个全面的过渡过程。向成人护理的次优过渡可能会对患者的长期护理产生破坏性和有害的后果。本文详细介绍了临床医生关于将青少年DMD患者从儿科过渡到成人神经科医生的共识结果,该共识可以作为最佳实践的指南,以确保患者在旅程的每个阶段都能获得持续的全面护理。
    方法:使用德尔菲法得出共识。指导小组(本文的作者)制定了53个声明,涵盖七个主题:定义过渡目标,准备病人,照顾者/父母和成人中心,儿科中心的过渡过程,多学科过渡摘要-原则,多学科过渡摘要-内容,首次访问成人中心,对转型的评价。这些声明与中东欧(CEE)的儿科和成人神经科医生分享,作为一项调查,要求他们对每个声明的同意程度。
    结果:来自60名应答者(54名完全应答和6名部分应答)的数据包括在数据集分析中。在100%的声明中达成了共识。
    结论:希望本次调查的结果列出了商定的最佳实践声明,和开发的转移模板文件,将被广泛使用,从而促进DMD青少年从儿科护理到成人护理的有效过渡。
    OBJECTIVE: An increasing number of patients with Duchenne muscular dystrophy (DMD) now have access to improved standard of care and disease modifying treatments, which improve the clinical course of DMD and extend life expectancy beyond 30 years of age. A key issue for adolescent DMD patients is the transition from paediatric- to adult-oriented healthcare. Adolescents and adults with DMD have unique but highly complex healthcare needs associated with long-term steroid use, orthopaedic, respiratory, cardiac, psychological, and gastrointestinal problems meaning that a comprehensive transition process is required. A sub-optimal transition into adult care can have disruptive and deleterious consequences for a patient\'s long-term care. This paper details the results of a consensus amongst clinicians on transitioning adolescent DMD patients from paediatric to adult neurologists that can act as a guide to best practice to ensure patients have continuous comprehensive care at every stage of their journey.
    METHODS: The consensus was derived using the Delphi methodology. Fifty-three statements were developed by a Steering Group (the authors of this paper) covering seven topics: Define the goals of transition, Preparing the patient, carers/parents and the adult centre, The transition process at the paediatric centre, The multidisciplinary transition summary - Principles, The multidisciplinary transition summary - Content, First visit in the adult centre, Evaluation of transition. The statements were shared with paediatric and adult neurologists across Central Eastern Europe (CEE) as a survey requesting their level of agreement with each statement.
    RESULTS: Data from 60 responders (54 full responses and six partial responses) were included in the data set analysis. A consensus was agreed across 100% of the statements.
    CONCLUSIONS: It is hoped that the findings of this survey which sets out agreed best practice statements, and the transfer template documents developed, will be widely used and so facilitate an effective transition from paediatric to adult care for adolescents with DMD.
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  • 文章类型: Journal Article
    目的:评估神经科医生中不良通道识别的评估者间和评估者内的可靠性,脑电图技术员,和天真的研究人员,并将其性能与用于检测坏信道的自动坏信道检测(ABCD)算法进行比较。 方法:六名神经科医生,十位脑电图技师,并要求6名幼稚的研究人员(总共22名评估人员)对1440个真实的颅内EEG通道进行评估。计算每组的评分者内和评分者间kappa统计量。然后,我们将每组与使用频谱和时域特征将通道分类为好或坏的ABCD算法进行比较。 结果:对我们参与者的频道评级的分析显示,每组中不同的评级者内部可靠性,组间没有显著差异。在神经学家和脑电图技术人员中,评估者间的可靠性是中等的,但在幼稚的参与者中最低。神经学家在评分方面表现出比脑电图技术人员略高的一致性。两组偶尔错误分类的平坦频道,参与者通常将重点放在评估的低频内容上。ABCD算法,相比之下,更依赖高频内容。逻辑回归模型显示了算法的评级和用户响应之间的线性关系,主要是好频道,但对于被评为糟糕的频道来说就不那么重要了。敏感性和特异性分析进一步强调了组间评分模式的差异,神经科医生表现出更高的灵敏度和更高的特异性。&#xD;意义:我们的研究揭示了人类对iEEG数据质量评估的偏见,甚至有经验的专业人士也倾向于忽略某些不良渠道,强调标准化的必要性,无偏见的方法。ABCD算法,超越人类评估者,提出了更可靠的iEEG解释和癫痫发作表征的自动化解决方案的潜力,提供一种不受人类偏见影响的可靠方法。 .
    Objective.To evaluate the inter- and intra-rater reliability for the identification of bad channels among neurologists, EEG Technologists, and naïve research personnel, and to compare their performance with the automated bad channel detection (ABCD) algorithm for detecting bad channels.Approach.Six Neurologists, ten EEG Technologists, and six naïve research personnel (22 raters in total) were asked to rate 1440 real intracranial EEG channels as good or bad. Intra- and interrater kappa statistics were calculated for each group. We then compared each group to the ABCD algorithm which uses spectral and temporal domain features to classify channels as good or bad.Main results.Analysis of channel ratings from our participants revealed variable intra-rater reliability within each group, with no significant differences across groups. Inter-rater reliability was moderate among neurologists and EEG Technologists but minimal among naïve participants. Neurologists demonstrated a slightly higher consistency in ratings than EEG Technologists. Both groups occasionally misclassified flat channels as good, and participants generally focused on low-frequency content for their assessments. The ABCD algorithm, in contrast, relied more on high-frequency content. A logistic regression model showed a linear relationship between the algorithm\'s ratings and user responses for predominantly good channels, but less so for channels rated as bad. Sensitivity and specificity analyses further highlighted differences in rating patterns among the groups, with neurologists showing higher sensitivity and naïve personnel higher specificity.Significance.Our study reveals the bias in human assessments of intracranial electroencephalography (iEEG) data quality and the tendency of even experienced professionals to overlook certain bad channels, highlighting the need for standardized, unbiased methods. The ABCD algorithm, outperforming human raters, suggests the potential of automated solutions for more reliable iEEG interpretation and seizure characterization, offering a reliable approach free from human biases.
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