Neonatologists

新生儿学家
  • 文章类型: Journal Article
    尽管越来越多的文献支持在新生儿中使用即时肺部超声(POC-LU),它在加拿大新生儿重症监护病房(NICU)的采用仍然有限。这项研究旨在确定医疗保健提供者在加拿大NICU实施POC-LU的看法和障碍。我们进行了一项针对新生儿学家的电子调查,新生儿研究员,新生儿护士从业人员,以及20个加拿大NICU的注册呼吸治疗师。调查包括一份28项问卷,分为四个部分:(1)参与者的人口统计数据和POC-LU设备的可用性,(2)POC-LU学习的经验和兴趣,(3)POC-LU作为诊断工具的感知,(4)在NICU中实施POC-LU的障碍。共有194名参与者完成了调查,新生儿科医生占多数(45%)。近一半的参与者(48%)报告了POC-LU的先前经验。使用POC-LU最普遍的适应症是诊断为胸腔积液(90%)。气胸(87%),和呼吸窘迫综合征(76%)。与会者认为采用POC-LU的主要障碍是缺乏培训和临床整合的训练有素的提供者。值得注意的是,大多数受访者(87%)表示对学习新生儿POC-LU非常感兴趣。基于从12个机构的NICU主任收集的响应进行的亚组分析得出的结果与整个参与者库的结果一致。结论:这项调查强调了POC-LU在NICU医疗保健提供者中的重要性。需要加拿大达成共识,以促进制定广泛的培训计划以及实施标准化的临床实践指南。已知内容:•近年来,护理点肺超声(POC-LU)已成为新生儿学的重要工具,彻底改变危重病婴儿的评估和管理。然而,它在加拿大新生儿重症监护病房的采用仍然有限。新增内容:•大多数加拿大医疗保健提供者对学习POC-LU技术表现出很高的兴趣。此外,POC-LU被认为是诊断和指导各种新生儿呼吸系统疾病干预的有用工具。尽管如此,缺乏专业知识成为在不同参与者群体中采用和实践的主要障碍,无论他们的临床经验水平如何.
    Despite the growing body of literature supporting the use of point-of-care lung ultrasound (POC-LU) in neonates, its adoption in Canadian neonatal intensive care units (NICUs) remains limited. This study aimed to identify healthcare providers\' perceptions and barriers to implementing POC-LU in Canadian NICUs. We conducted an electronic survey targeting neonatologists, neonatal fellows, neonatal nurse practitioners, and registered respiratory therapists in 20 Canadian NICUs. The survey comprised a 28-item questionnaire divided into four sections: (1) participants\' demographics and availability of POC-LU equipment, (2) experience and interest in POC-LU learning, (3) perception of POC-LU as a diagnostic tool, and (4) barriers to POC-LU implementation in NICUs. A total of 194 participants completed the survey, with neonatologists comprising the majority (45%). Nearly half of the participants (48%) reported prior experience with POC-LU. The most prevalent indications for POC-LU use were diagnosis of pleural effusion (90%), pneumothorax (87%), and respiratory distress syndrome (76%). Participants identified the primary barrier to POC-LU adoption as the lack of trained providers available for both training and clinical integration. Notably, most respondents (87%) expressed keen interest in learning neonatal POC-LU. A subgroup analysis based on the responses collected from NICU-directors of 12 institutions yielded results consistent with those of the overall participant pool.     Conclusion: This survey underscores the perceived importance of POC-LU among NICU healthcare providers. A Canadian consensus is required to facilitate the development of widespread training programs as well as standardized clinical practice guideline for its implementation. What is Known: • In recent years, point-of-care lung ultrasound (POC-LU) has emerged as an important tool in neonatology, revolutionizing the assessment and management of critically ill infants. However, its adoption in Canadian Neonatal Intensive Care Units remains limited. What is New: • Most Canadian healthcare providers showed high level of interest in learning POC-LU techniques. Additionally, POC-LU was perceived as a useful tool for diagnosis and guiding intervention in various neonatal respiratory diseases. Nonetheless, the lack of expertise emerged as the primary barrier to its adoption and practice across different groups of participants regardless of their clinical experience level.
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  • 文章类型: Journal Article
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  • 文章类型: Journal Article
    目的:本研究旨在探讨以色列新生儿学家对妊娠22-24周早产儿复苏的观点以及他们对父母偏好的考虑。调查了影响医生决定生存边缘的因素,以及他们的决定与国家临床指南一致的程度。
    方法:使用47个问题的在线问卷进行描述性和相关性研究。
    结果:以色列127名活跃的新生儿学家中有90名(71%)做出了回应。74%,分别有50%和16%的受访者认为,在出生时进行复苏和全面治疗,有损于妊娠22,23和24周时出生的婴儿的最大利益,分别。受访者关于极度早产儿复苏的决定显示出明显的差异,并且始终与国家临床指南或对这些新生儿的最佳利益的看法不一致。性别,经验,出生国和宗教信仰水平都与受访者对治疗决定的偏好有关。个人价值观和对法律问题的关注也被认为会影响决策。
    结论:以色列新生儿学家在妊娠22-24周出生的极早产儿的产房管理方面观察到显著差异,通常特别强调尊重父母的意愿。目前的国家准则没有完全涵盖广泛的方法。该国的指导方针应反映现有的意见范围,在制定指导方针和建议之前,可能是通过对护理人员进行广泛调查。
    OBJECTIVE: This study aims to examine the perspectives of neonatologists in Israel regarding resuscitation of preterm infants born at 22-24 weeks gestation and their consideration of parental preferences. The factors that influence physicians\' decisions on the verge of viability were investigated, and the extent to which their decisions align with the national clinical guidelines were determined.
    METHODS: Descriptive and correlative study using a 47-questions online questionnaire.
    RESULTS: 90 (71%) of 127 active neonatologists in Israel responded. 74%, 50% and 16% of the respondents believed that resuscitation and full treatment at birth are against the best interests of infants born at 22, 23 and 24 weeks gestation, respectively. Respondents\' decisions regarding resuscitation of extremely preterm infants showed significant variation and were consistently in disagreement with either the national clinical guidelines or the perception of what is in the best interest of these newborns. Gender, experience, country of birth and the level of religiosity were all associated with respondents\' preferences regarding treatment decisions. Personal values and concerns about legal issues were also believed to affect decision-making.
    CONCLUSIONS: Significant variation was observed among Israeli neonatologists regarding delivery room management of extremely premature infants born at 22-24 weeks gestation, usually with a notable emphasis on respecting parents\' wishes. The current national guidelines do not fully encompass the wide range of approaches. The country\'s guidelines should reflect the existing range of opinions, possibly through a broad survey of caregivers before setting the guidelines and recommendations.
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  • 文章类型: Journal Article
    简介:美国儿科学会(AAP)的最新临床报告得出的结论是,目前的证据不支持对早产儿常规普遍施用益生菌。特别是那些出生体重<1000克的人。尽管如此,美国新生儿重症监护病房(NICU)中益生菌的使用正在增加.目标:与AAP的围产期新生儿医学合作,我们进行了一项全国调查,以获得新生儿学家对益生菌使用的意见。方法:通过电子邮件向3000名新生儿科医师发送调查问卷。结果:在3000名潜在受访者中,249(8.3%)完成了调查。在23个不同的NICU工作的75名(30%)新生儿学家报告说,他们在实践中使用了益生菌,而在54个不同的NICU工作的168名(70%)新生儿学家报告没有使用益生菌。在那些目前不使用益生菌的人中,49%的人表示他们会考虑在未来使用益生菌,而不是12%的人表示他们不会使用益生菌。使用益生菌最常见的适应症是平均胎龄<32周,平均出生体重<1500克。在平均胎龄为35周时停用益生菌。开益生菌处方的受访者更有可能在没有团契或住院医师培训的环境中工作(48%对20%)。与非使用者相比,益生菌使用者更经常来自西方(29%对7%),而较少来自东北(5%对34%)。使用益生菌的比例因NICU大小而没有显着差异,NICU级别,或在NICU工作多年。SimilacTri-Blend,Evolve,和Culturelle是受访者NICU中使用的三大益生菌。结论:尽管大多数受访者目前并未在其NICU中使用益生菌,大量非使用者对将来使用益生菌感兴趣.美国NICU中使用的益生菌品牌继续存在差异。
    Introduction: Most recent clinical reports from the American Academy of Pediatrics (AAP) concluded current evidence does not support routine universal administration of probiotics to preterm infants, particularly those with birth weight <1000 grams. Despite this, the use of probiotics is increasing in US neonatal intensive care units (NICU).Objectives: Collaborating with the Perinatal Neonatal Medicine of AAP, we conducted a national survey to obtain neonatologist opinion on probiotics use.Methods: Survey questionnaires were sent to 3000 neonatologists via email.Results: Of 3000 potential respondents, 249 (8.3 %) completed the survey. Seventy-five (30%) neonatologists working in 23 different NICUs reported using probiotics in their practice, while 168 (70%) neonatologists working in 54 different NICUs reported not using probiotics. Of those not currently use probiotics, 49% indicated they would consider using probiotics in the future vs. 12% indicating they would not use probiotics. The most common indication for probiotics use was average gestational age < 32 weeks and mean birth weight < 1500 grams. Probiotics were discontinued at mean gestational age of 35 weeks. Respondents who prescribe probiotics were more likely to work in a setting without fellowship or residency training (48% vs 20%). Probiotics users were more often from the West (29 % vs 7%) and less often from Northeast (5% vs 34%) compared to non-users. The proportion of those using probiotics did not significantly differ by NICU size, NICU level, or years working in a NICU. Similac Tri-Blend, Evivo, and Culturelle were the top three probiotics used in the respondent\'s NICU.Conclusion: Though a majority of respondents are not currently using probiotics in their NICU, a large number of nonusers are interested in using probiotics in the future. Differences continue to exist in the brand of probiotics used in US NICUs.
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  • 文章类型: Journal Article
    目的:开发一种通用且国际适用的数据变量模板,用于报告医院间新生儿重症监护转运。
    方法:五步德尔菲法。
    方法:通过电子邮件指导一组专家通过正式的共识过程。
    方法:来自加拿大的12名新生儿重症监护运输专家,丹麦,挪威,英国和美国。四个女人和八个男人。专家是新生儿学家,麻醉师,重症监护护士,麻醉护士,医疗领导人,研究人员和家长代表。
    方法:最终模板中包含了37个数据变量。
    结果:在具有定义的37个数据变量的模板上达成了共识。每个运输要注册的30个变量和运输服务系统每年注册的7个变量。类别结构下的11个数据变量,20项在进程中,6项在结果中。
    结论:我们开发了一个带有一组数据变量的模板,用于新生儿重症监护运输。注册相同的数据将启用更大的数据集和比较服务。
    OBJECTIVE: To develop a general and internationally applicable template of data variables for reporting interhospital neonatal intensive care transports.
    METHODS: A five-step Delphi method.
    METHODS: A group of experts was guided through a formal consensus process using email.
    METHODS: 12 experts in neonatal intensive care transports from Canada, Denmark, Norway, the UK and the USA. Four women and eight men. The experts were neonatologists, anaesthesiologists, intensive care nurse, anaesthetic nurse, medical leaders, researchers and a parent representative.
    METHODS: 37 data variables were included in the final template.
    RESULTS: Consensus was achieved on a template of 37 data variables with definitions. 30 variables to be registered for each transport and 7 for annual registration of the system of the transport service. 11 data variables under the category structure, 20 under process and 6 under outcome.
    CONCLUSIONS: We developed a template with a set of data variables to be registered for neonatal intensive care transports. To register the same data will enable larger datasets and comparing services.
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  • 文章类型: Journal Article
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  • 文章类型: Editorial
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  • 文章类型: Journal Article
    新生儿的中枢神经系统(CNS)肿瘤相对罕见,并且在病因学方面与儿童后期发生的肿瘤相比存在差异。临床特征,location,组织学和预后。临床表现变化很大。即使最常见的临床症状是大头畸形,有许多其他非特异性症状相关。预后通常较差,总生存率低于30%。手术仍然是新生儿中枢神经系统肿瘤的主要治疗方法,旨在进行全面切除,与预后和总体预后直接相关。化疗是唯一的辅助疗法,而由于严重的后遗症,在三岁以下可以避免放疗。因此,对这些肿瘤进行分子表征以提高诊断的准确性并确定新的治疗靶标的重要性。这篇综述的目的是描述这些肿瘤的主要特征及其治疗的最新进展,以便在产前阶段认识到这些病理,并创建一个多学科团队,提供最佳治疗,同时最大限度地减少长期并发症的风险。新生儿学家在早期检测中起着关键作用,诊断评估,这些新生儿的管理和支持性护理。结论:本综述的目的是描述这些肿瘤的主要特征及其治疗的最新进展,以确保有助于新生儿学家识别它们的基本知识,并创建一个多学科团队,提供最佳治疗,同时最大限度地减少长期并发症的风险。已知:•新生儿CNS肿瘤相对罕见,并且它们的早期识别对于确定最佳诊断-治疗管理是重要的。•手术是新生儿中枢神经系统肿瘤的主要治疗方法。手术切除的程度与预后和结果直接相关。新增内容:•必须考虑诸如癌症易感性综合征之类的易感状况。•可以通过分子表征鉴定靶向药物和其他治疗策略。
    Central nervous system (CNS) tumours in neonates are relatively rare and present differently when compared with those occurring later in childhood in terms of aetiology, clinical features, location, histology and prognosis. The clinical presentation is extremely variable. Even if the most frequent clinical sign is a macrocephaly, there are many other non-specific symptoms associated. The prognosis is usually poor with overall survival of less than 30%. Surgery continues to be the primary treatment for neonatal CNS tumours, aiming for a gross total resection, directly correlated with prognosis and the overall outcome. The chemotherapy is the only adjuvant therapy whereas the radiotherapy is avoided under three years of age because of the severe sequelae. Hence the importance of molecular characterization of these neoplasms in order to improve the accuracy of the diagnosis and identify new therapeutic targets. The aim of this review is to describe the main characteristics of these tumours and the recent advances in their treatment in order to recognize these pathologies in the prenatal period and create a multidisciplinary team providing the best possible treatment while minimising the risk of long-term complications. Neonatologists play a key role in the early detection, diagnostic evaluation, management and supportive care of these neonates.  Conclusion: The aim of this review is to describe the main characteristics of these tumours and the recent advances in their treatment in order to ensure the essential knowledge that will help the neonatologist identify them and create a multidisciplinary team providing the best possible treatment while minimising the risk of long-term complications. What is Known: • Neonatal CNS tumours are relatively rare and their early identification is important to identify the best diagnostic-therapeutic management. • Surgery is the main treatment of neonatal CNS tumours. The extent of surgical resection directly correlates with prognosis and outcome. What is New: • Predisposing conditions such as Cancer Predisposition Syndromes must be considered. • Targeted drugs and other therapeutic strategies can be identified through molecular characterization.
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  • 文章类型: Journal Article
    血小板减少症的病因是高度多样化的;然而,早期新生儿血小板减少症可能在极低体重新生儿中更为常见.因此,在这项研究中,我们旨在研究沙特阿拉伯目前的新生儿血小板(PLT)输血实践.这是一项横断面在线调查研究,于2022年10月至12月进行。使用便利抽样来招募参与者。在这项研究中,我们在广泛文献综述的基础上,制定了一项调查问卷,以调查当前新生儿PLT输血实践.共有81名新生儿科医生参加。其中绝大多数(85.2%)是在三级新生儿重症监护病房执业,60.0%的人报告他们输注PLT超过1小时。大约53%的人报告说他们通常每次PLT输血需要10mL/kg。多达34.6%的研究参与者报告说他们在其实践单位中使用汇集的全血衍生的PLT产品。几乎一半(48.0%)的研究参与者报告说,他们在其执业单位编写了PLT输血指南,81.1%的人报告指南中规定了PLT输血阈值.新生儿血小板减少症通常用PLT输血治疗。鉴于最近的证据表明这样做可能适得其反,应降低PLT输血标准。然而,对于PLT计数是否构成需要为新生婴儿输血的医疗紧急情况,存在一些分歧。此外,由于缺乏明确的协议,沙特阿拉伯的PLT输液管理存在很大差异。需要严格的新生儿PLT输血标准和精心计划的临床研究来解决这些不同方法的风险和/或益处。
    The etiologies of thrombocytopenia are highly diverse; however, early neonatal thrombocytopenia might be more common among extremely low-weight neonates. Therefore, in this study, we aimed to examine the current neonatal platelet (PLT) transfusion practices in Saudi Arabia. This is a cross-sectional online survey study that was conducted between October and December 2022. Convenience sampling was used to recruit the participants. In this study, we developed a questionnaire based on an extensive literature review to examine current neonatal PLT transfusion practices. A total of 81 neonatologists participated. The vast majority of them (85.2%) were practicing in a level 3 neonatal intensive care unit, with 60.0% of them reporting that they transfuse PLTs over 1 hour. Around 53% reported that they typically order 10 mL/kg per PLT transfusion. Up to 34.6% of the study participants reported that they use pooled whole-blood-derived PLT products in their practicing unit. Almost half (48.0%) of the study participants reported that they have written guidelines for PLT transfusion in their practicing unit, with 81.1% reporting that the PLT transfusion threshold was stated in the guidelines. Neonatal thrombocytopenia is typically treated with PLT transfusions. PLT transfusion criteria should be lowered in light of recent evidence suggesting that doing so may be counterproductive. However, there is some disagreement about whether a PLT count constitutes a medical emergency requiring a transfusion for a newborn baby. Furthermore, there is a great deal of variation in the administration of PLT infusions in Saudi Arabia because of the absence of clear protocols. Strict neonatal PLT transfusion standards and carefully planned clinical research are needed to address the risks and/or benefits of these diverse methods.
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