背景:本研究旨在确定中国门诊新生儿科医师关于乳糖不耐受的知识差距的具体领域,以及评估医院乳糖不耐受检测的可用性。
方法:对来自144家医院的总共278名门诊新生儿专家进行了调查。探索意识水平,诊断,和治疗新生儿乳糖不耐受的新生儿在门诊设置,设计了多中心横断面调查。对所有变量进行基于频率和百分比分布的描述性分析。
结果:大多数受访者是综合医院和妇产科/妇幼保健医院的高级医生(256,92.09%),有超过10年的经验,主要为副主任医师和主任医师(211,75.90%)。相当比例的参与者(236,84.89%)认为新生儿乳糖不耐受在临床实践中往往被忽视。当调查新生儿乳糖不耐受的最常见症状时,腹泻由142名(51.08%)受访者选择,其次是腹胀和牛奶反流或呕吐(71,25.54%)。其他症状包括不明原因的哭闹(36,12.85%),粪便与牛奶瓣或泡沫(15,5.40%),和增加排气(14,5.04%)。此外,调查结果表明,受访者医院诊断新生儿乳糖不耐受的最常用方法是尿半乳糖定性检测(78,28.06%)。在受访者中,137(49.28%)表示他们的医院无法检测乳糖不耐受。治疗乳糖不耐受,新生儿学家主要选择外源性乳糖酶而不是无乳糖的配方奶。
结论:这项研究揭示了中国新生儿学家对新生儿乳糖不耐受的认识,揭示了一些知识差距。乳糖不耐受相关检查在医院的迅速普及和开展将对新生儿乳糖不耐受的管理产生积极的促进作用。
BACKGROUND: This study aimed to identify the specific areas of knowledge gaps regarding lactose intolerance among
neonatologists in Chinese outpatient settings as well as to assess the availability of lactose intolerance testing in hospitals.
METHODS: A total of 278
neonatologists in outpatient settings from 144 hospitals were surveyed. To explore the awareness level, diagnosis, and treatment of neonatal lactose intolerance among
neonatologists in outpatient settings, a multicenter cross-sectional survey was designed. Descriptive analysis based on frequency and percent distribution was performed for all variables.
RESULTS: Most respondents were senior doctors (256, 92.09%) from general hospitals and maternity/maternal and child health hospitals, had over 10 years of experience, and were dominantly associate chief physicians and chief physicians (211, 75.90%). A significant proportion of the participants (236, 84.89%) believed that neonatal lactose intolerance tends to be overlooked during clinical practice. When the most common symptoms of neonatal lactose intolerance were surveyed, diarrhea was selected by 142 (51.08%) respondents, followed by bloating and milk regurgitation or emesis (71, 25.54%). Other symptoms included unexplained crying (36, 12.85%), stool with milk flap or foam (15, 5.40%), and increased venting (14, 5.04%). Furthermore, the survey results indicated that the most common method for diagnosing neonatal lactose intolerance in the respondents\' hospitals was qualitative test for urinary galactose (78, 28.06%). Of the respondents, 137 (49.28%) stated that their hospital could not test for lactose intolerance. For treating lactose intolerance, the
neonatologists primarily opted for exogenous lactase rather than lactose-free formula milk.
CONCLUSIONS: This study sheds light on Chinese
neonatologists\' awareness of neonatal lactose intolerance, revealing some knowledge gaps. The expeditious popularization and conduct of lactose intolerance-related examinations in hospitals will have a positive stimulative effect on the management of lactose intolerance in newborns.