Mott

MOTT
  • 文章类型: Case Reports
    被称为“Mott细胞”的浆细胞存在称为“罗素体”的免疫球蛋白的不可分泌积累。它的存在与血液肿瘤有关,但它可以出现在慢性炎症过程中。消化道内最常见的是与幽门螺杆菌感染相关的胃窦。我们的患者增加了罕见的胃外病例,其中与幽门螺杆菌的关联不一致。我们发现了与这些病例相关的下消化道和泌尿系统肿瘤的频繁出现,肿瘤区域循环细胞因子的表达导致浆细胞过度活化。这种可能的关联可能使我们了解有关肿瘤环境的数据,并为我们的早期诊断或未来的治疗目标服务。
    Plasma cells known as \"Mott cells\" present non-secretable accumulations of immunoglobulins called \"Russell bodies\". Its presence is related to hematological neoplasms, but it can appear in chronic inflammatory processes. The most common occurrence within the digestive tract is the gastric antrum associated with H. pylori infection. Our patient is added the rare extragastric cases where the association with H. pylori is inconsistent. We have found a frequent appearance of lower digestive and urological neoplasms in relation to these cases, justified by the expression of circulating cytokines in the tumor area that lead to the overactivation of plasma cells. This possible association could lead us to know data about the tumor environment and serve us for early diagnosis or future therapeutic targets.
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  • 文章类型: Case Reports
    我们在此报告了一例不寻常的病例,该病例是一名62岁的女性,没有相关的既往病史。由非结核分枝杆菌引起的起搏器相关感染很少见,但可导致大量的发病率和死亡率。恶性分枝杆菌在起搏器感染中很少报道,并且由于对许多抗微生物剂的耐药性而具有挑战性。在我们的案例中,患者的起搏器感染对标准治疗没有反应,导致完整的设备删除。我们的案例凸显了治疗Mageritense分枝杆菌的挑战,特别是我们的患者比以前文献中报道的更耐药。据我们所知,此类病例在文献中很少报道。
    We herein report an unusual case of Mycobacterium mageritense pacemaker infection at generator site in a 62-year old female with no pertinent past medical history. Pacemaker-related infections caused by nontuberculous mycobacteria are rare but can lead to significant morbidity and mortality. Mycobacterium mageritense is rarely reported in pacemaker infections and is challenging to treat due to resistance to many antimicrobial agents. In our case, the patient\'s pacemaker infection did not respond to standard treatment, leading to complete device removal. Our case highlights the challenges in treating Mycobacterium Mageritense, especially that our patient had a more resistant organism than those reported previously in literature. To our knowledge, such cases are infrequently reported in the literature.
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  • 文章类型: Journal Article
    单层1T-NbSe2和1T-TaSe2的推定的Mott电荷密度波(CDW)相最近引起了很多兴趣,这是由于其Mott-Hubbard态的意外轨道结构以及与量子自旋液体具有自旋费米表面的奇特可能性有关的超结构。轨道结构和上层建筑的起源是,然而,难以捉摸。通过使用密度泛函理论计算,我们发现这些CDW相可以具有替代的亚稳态结构,以阴离子(Se)为中心的簇,与以阳离子(Nb或Ta)为中心的大卫星团的流行模型相反。该结构可以通过从实验中常用的双层石墨烯/SiC衬底的电荷转移来稳定。以阴离子为中心的结构具有与DS团簇相似的电荷转移绝缘体的电子能带结构,但自然地从其原子结构解释了上哈伯德能带的轨道结构。此外,这种能带结构表现出费米表面嵌套,可能会自发地将对称性破坏为实验观察到的3×3-R30°上部结构。所产生的上部结构的基态显示为平凡的带状绝缘体,与异国情调的提议相反。这一结果强调了这些异质单层的巨大结构灵活性,为此,非常需要对原子结构和与底物的相互作用进行仔细研究。
    The putative Mott charge density wave (CDW) phases of monolayer 1T-NbSe2 and 1T-TaSe2 have attracted a lot of recent interest due to the unexpected orbital texture of their Mott-Hubbard states and the superstructure related to an exotic possibility of a quantum spin liquid with a spinon Fermi surface. The origins of the orbital texture and the superstructure have been, however, elusive. We find by using density functional theory calculations that these CDW phases can have an alternative metastable structure, an anion (Se) centered cluster, in contrast to the prevailing model of a cation (Nb or Ta) centered David star cluster. This structure can be stabilized by the charge transfer from the bilayer graphene/SiC substrate used commonly in the experiments. The anion-centered structure has a similar electronic band structure of a charge transfer insulator to that of DS clusters but naturally explains the orbital texture of the upper Hubbard band from simply its atomic structure. Moreover, this band structure exhibits a Fermi surface nesting to possibly break the symmetry spontaneously into a 3×3-R30° superstructure observed experimentally. The resulting ground state of the superstructure is shown to be a trivial band insulator, in contrast to exotic proposals. This result emphasizes the huge structural flexibility of these heteroexpitaxial monolayers, for which careful studies on atomic structures and interactions with substrates are highly requested.
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  • 文章类型: Case Reports
    暂无摘要。
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  • 文章类型: Case Reports
    未经证实:在4例移植后6个月内出现的肾移植成年受者中,快速生长的分枝杆菌与脓肿分枝杆菌和/或螯合分枝杆菌术后伤口感染的病例系列。
    UNASSIGNED:我们报告4例肾移植受者术后感染NTM-69岁,术后伤口感染,经微生物证实为脓肿分枝杆菌,停止治疗,并进一步出现腹腔内脓肿。下一个病例为61岁男性,在手术部位出现结节状肿胀,美国发现腹内肌肉脓肿的结果被测试为培养物,对车内分枝杆菌和脓肿呈阳性。第三例为34岁男性,出现手术伤口感染,ZN染色显示AFB阳性。最后,46岁男性患者已知高血压和E.S.R.D,有培养证明脓肿分枝杆菌手术伤口感染。所有四个病例都在菲律宾的不同中心进行了肾脏移植。
    UNASSIGNED:非结核分枝杆菌感染是肾移植受者发病的重要原因,高度怀疑早期诊断和治疗对成功预后至关重要。
    UNASSIGNED: Case series of Rapidly growing Mycobacterial Post-operative wound infection with Mycobacterium Abscessus and/or Mycobacterium Chelone in 4 cases of kidney transplant adult recipient who presented within 6 months of transplant.
    UNASSIGNED: We report 4 cases of Renal transplant recipients with post-surgical site infection with NTM-69-year-old with post-surgical wound infection with microbiologically proven Mycobacterium Abscessus who discontinued treatment and further presented with intra-abdominal abscess. Next case was 61 years male presented with nodular swellings at surgical site with US findings of intra-abdominal muscle abscess was tested culture positive for Mycobacterium Chelonae and Abscessus.Third case was 34 years male presented with surgical wound infection which was positive for AFB by ZN stain. Lastly,46 years old male patient known hypertensive and E.S.R.D, had culture proven Mycobacterium Abscessus surgical wound infection. All the four cases had their renal transplant at Philippines at different centres.
    UNASSIGNED: Nontuberculous mycobacteria infection is important cause of morbidity in kidney transplant recipient and high index of suspicion with early diagnosis and treatment is crucial for successful outcome.
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  • 文章类型: Journal Article
    目的:鸟分枝杆菌复合体(MAC)是分枝杆菌科内的一组耐酸细菌。它们的细胞壁具有许多消毒剂不可渗透的特定结构。分枝杆菌在环境中广泛存在,也可以在食物中找到。本文的目的是回顾有关感染源的知识的现状,人类和动物MAC疾病的症状和治疗,并总结了鉴定细菌的可用方法。它特别关注MAC细菌的人畜共患潜力和人与动物之间可能的传播途径,包括可能的食源性路线。
    未经证实:MAC细菌感染发生在有免疫能力的人和有功能倾向和免疫力受损的人中,特别是在HIV感染或免疫抑制治疗期间。人类MAC感染的发病率正在增长,最常见的感染形式是肺部疾病(MTC-PD);然而,关于鸟副结核分枝杆菌(MAP)在克罗恩病发展中的作用,有相互矛盾的报道。MAC细菌也可以攻击牲畜,家庭宠物,和野生动物。不幸的是,治疗时间长,通常由于微生物复发而失败;也有越来越多的证据表明MAC细菌正在发展多药耐药性。
    结论:尽管正在创造新的抗生素来抑制鸟分枝杆菌的生长和分裂,显然需要进一步研究与MAC细菌相关的毒力因子.进一步的研究还应该检查MAP在克罗恩病病因中的作用。
    OBJECTIVE: The Mycobacterium avium complex (MAC) is a group of acid-resistant bacteria within the Mycobacteriaceae. Their cell walls have a specific structure impervious to many disinfectants. Mycobacteria are widespread in the environment and can also be found in food. This aim of the article is to review the current state of knowledge about the sources of infection, symptoms and treatment of MAC diseases in humans and animals, and summarizes the available methods for identifying the bacteria. It pays a special attention to the zoonotic potential of MAC bacteria and possible routes of transmission between humans and animals, including possible food-borne routes.
    UNASSIGNED: MAC bacterial infections occur both in immunocompetent people and those with functional predispositions and compromised immunity, particularly during HIV infection or immunosuppressive treatment. The incidence of MAC infections in humans is growing, with the most common form of infection being pulmonary disease (MTC-PD); however, there are conflicting reports on the role of Mycobacterium avium paratuberculosis (MAP) in the development of Crohn\'s disease. MAC bacteria can also attack livestock, household pets, and wild animals. Unfortunately, treatment is lengthy and often fails due to microbiological relapse; there is also increasing evidence of MAC bacteria are developing multi-drug resistance.
    CONCLUSIONS: Although new antibiotics are being created to inhibit the growth and division of Mycobacterium avium, there is clearly a need for further research into the virulence factors associated with MAC bacteria. Further studies should also examine the role of MAP in the etiopathogenesis of Crohn\'s disease.
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  • 文章类型: Case Reports
    We report a case of chyluria caused by Mycobacterium fortuitum infection in a sixty-four year old male, who was successfully treated with two weeks of amikacin, trimethoprim-sulfamethoxazole and levofloxacin followed by twenty four weeks of levofloxacin and doxycycline.
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  • 文章类型: Journal Article
    The Mott state in 1T-TaS2 is predicted to host quantum spin liquids (QSLs). However, its insulating mechanism is controversial due to complications from interlayer coupling. Here, we study the charge transfer state in monolayer 1T-NbSe2, an electronic analogue to TaS2 exempt from interlayer coupling, using spectroscopic imaging scanning tunneling microscopy and first-principles calculations. Monolayer NbSe2 surprisingly displays two types of star of David (SD) motifs with different charge transfer gap sizes, which are interconvertible via temperature variation. In addition, bilayer 1T-NbSe2 shows a Mott collapse by interlayer coupling. Our calculation unveils that the two types of SDs possess distinct structural distortions, altering the effective Coulomb energies of the central Nb orbital. Our calculation suggests that the charge transfer gap, the same parameter for determining the QSL regime, is tunable with strain. This finding offers a general strategy for manipulating the charge transfer state in related systems, which may be tuned into the potential QSL regime.
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  • 文章类型: Journal Article
    已开发出用于切割和携带系统的大型和矮小的象草品种。矮人克隆具有更好的消化率;另一方面,高大的品种生产力更高。目的是验证最推荐用于切割和携带的草:高大(大象B和IRI-381)或矮(台湾A-1462.37和Mott)大象草品种,以喂养24只雄性绵羊,年龄在4至5个月之间,未阉割,体重约24.08±1.76kg,按摄入量取样,消化率,性能,摄食行为,氮平衡,微生物蛋白质合成,代谢参数,和瘤胃降解性。本研究分为两个实验:实验1历时38天,7个用于适应,31个用于数据收集。向大象草品种提供矿物混合物。收集的数据是摄入量,消化率,摄食行为,代谢参数,微生物蛋白质合成,和性能提交给一个完全随机的设计。对于实验2,对三只瘤胃瘘动物进行取样,持续20天。在这种情况下,在分裂区设计中采用随机区组.两种设计均为P<0.05,并通过SAS统计软件进行分析。莫特和台湾A-1462.37品种提供了更多的摄入量,消化率,体重增加,喂食时间,氮保留,微生物蛋白质合成的生产和效率,干物质(DM)和中性洗涤纤维(NDF)降解,DM,粗蛋白,NDF,但反省时间比大象B和IRI-381短。葡萄糖也有显著差异,甘油三酯,血浆尿素,血清总蛋白,尿尿素(mg/L),和尿中尿素排泄(毫克/天)。矮象草品种莫特和台湾A-1462.37比高大的大象B和IRI-381具有更大的营养价值。矮象草建议用于切割和携带系统。
    Tall- and dwarf-sized elephant grass cultivars have been developed for cut-and-carry system. Dwarf clones have better digestibility; on the other hand, tall-sized cultivars are more productive. The aim was to verify which grass would be most recommended for cut-and-carry: tall-sized (Elephant B and IRI-381) or dwarf (Taiwan A-146 2.37 and Mott) elephant grass cultivars to feed 24 male sheep, aged between 4 and 5 months, uncastrated, weighing approximately 24.08 ± 1.76 kg body weight which were sampled on intake, digestibility, performance, ingestive behavior, nitrogen balance, microbial protein synthesis, metabolic parameters, and ruminal degradability. This research was divided into two experiments: experiment 1 lasted 38 days, seven for adaptation and 31 for data collection. Elephant grass cultivars were supplied with a mineral mixture. Data collected were intake, digestibility, ingestive behavior, metabolic parameters, microbial protein synthesis, and performance submitted to a completely randomized design. For experiment 2, three rumen fistulae animals were sampled, lasting 20 days. In this case, a randomized block in split-plot design was applied. Both designs were with P < 0.05 and analyzed through SAS statistical software. Mott and Taiwan A-146 2.37 cultivars provided greater intake, digestibility, weight gain, feeding time, nitrogen retention, production and efficiency of microbial protein synthesis, dry matter (DM) and neutral detergent fiber (NDF) degradability, and DM, crude protein, and NDF, but shorter rumination time rather than Elephant B and IRI-381. There was also a significant difference for glucose, triglycerides, plasma urea, total serum protein, urinary urea (mg/L), and urea excretion in urine (mg/day). Dwarf elephant grass cultivars as Mott and Taiwan A-146 2.37 have greater nutritional value than tall-sized Elephant B and IRI-381. Dwarf elephant grass is recommended for cut-and-carry system.
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  • 文章类型: Journal Article
    The burden of non-tuberculous mycobacterial (NTM) disease is increasing worldwide but still its diagnosis is delayed and it is mistaken as multidrug-resistant tuberculosis (MDR-TB).The present study was performed to develop a multiplex PCR assay for detection and identification of clinically most common NTM to the species level from pulmonary samples.
    Out of 50 isolates, 26 were identified as Mycobacterium kansasii (MK), 20 were identified as Mycobacterium abscessus (MA) and 4 were identified as Mycobacterium avium complex (MAC) through multiplex PCR and further confirmed by sequencing.
    Our study showed that multiplex PCR assay is a simple, convenient, and reliable technique for detection and differential identification of major NTM species.
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