Abstract：
Plasma cells known as \"Mott cells\" present non-secretable accumulations of immunoglobulins called \"Russell bodies\". Its presence is related to hematological neoplasms, but it can appear in chronic inflammatory processes. The most common occurrence within the digestive tract is the gastric antrum associated with H. pylori infection. Our patient is added the rare extragastric cases where the association with H. pylori is inconsistent. We have found a frequent appearance of lower digestive and urological neoplasms in relation to these cases, justified by the expression of circulating cytokines in the tumor area that lead to the overactivation of plasma cells. This possible association could lead us to know data about the tumor environment and serve us for early diagnosis or future therapeutic targets.
摘要：
被称为“Mott细胞”的浆细胞存在称为“罗素体”的免疫球蛋白的不可分泌积累。它的存在与血液肿瘤有关，但它可以出现在慢性炎症过程中。消化道内最常见的是与幽门螺杆菌感染相关的胃窦。我们的患者增加了罕见的胃外病例，其中与幽门螺杆菌的关联不一致。我们发现了与这些病例相关的下消化道和泌尿系统肿瘤的频繁出现，肿瘤区域循环细胞因子的表达导致浆细胞过度活化。这种可能的关联可能使我们了解有关肿瘤环境的数据，并为我们的早期诊断或未来的治疗目标服务。
