Meckel Diverticulum

Meckel 憩室
  • 文章类型: Case Reports
    背景:异位胃粘膜(HGM)可以位于胃肠道的各个部位。作为小肠的一种罕见异常,肠套叠会变得复杂,阻塞,消化道出血,甚至腹膜炎,导致死亡。
    方法:本病例报告集中于一名12岁的中东男孩,他出现了几天的便血和腹痛。标记的红细胞(RBC)扫描和Tech扫描显示下腹部胃肠道出血,高度暗示诊断为Meckel憩室。随后,剖腹探查术显示回肠末端有连续和分散的粘膜病变,并有各种大小的多发性息肉。Meckel的憩室不存在,患者接受了切除和一期吻合治疗。切除的组织显示广泛的异位胃粘膜和息肉样组织。患者恢复顺利,手术后四天出院。手术后六个月内症状没有复发。
    结论:我们的病例表明,尽管在回肠末端有多个息肉样胃异位症,应作为消化道出血的鉴别诊断之一。
    BACKGROUND: Heterotopic gastric mucosa (HGM) can be located in various parts of the gastrointestinal tract. As a rare anomaly in the small intestine, it can become complicated by intussusception, obstruction, gastrointestinal bleeding, and even peritonitis, leading to death.
    METHODS: This case report focuses on a 12-year-old Middle Eastern boy who presented with hematochezia and abdominal pain for a couple of days. A tagged Red blood cell (RBC) scan and Technetium scan revealed gastrointestinal bleeding at the lower abdomen, highly suggestive of the diagnosis of Meckel\'s diverticulum. Subsequently, exploratory laparotomy revealed contiguous and scattered mucosal lesions with multiple polyps of various sizes in the terminal ileum. Meckel\'s diverticulum was absent, and the patient was treated with resection and primary anastomosis. The resected tissue revealed extensive ectopic gastric mucosa and polypoid tissues. The patient recovered uneventfully and was discharged four days after the surgery. The symptoms did not recur within six months after his surgery.
    CONCLUSIONS: Our case demonstrated that despite the rarity of multiple polypoid gastric heterotopias in the terminal ileum, it should be considered as one of the differential diagnoses of gastrointestinal tract bleeding.
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  • 文章类型: Letter
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  • 文章类型: Journal Article
    背景:Meckel憩室(MD)的中关节带(MDB)是一种罕见的,然而,成人小肠梗阻(SBO)的显着病因。由于非特异性症状和具有挑战性的诊断,术前临床怀疑和战略管理对于获得最佳结果至关重要.因此,我们提出了一个病例,其中有策略地进行腹腔镜手术以减轻肠梗阻,由于SBO的术前诊断,怀疑是继发于伴有MDB的MD。
    方法:一名32岁男性患者表现为上腹痛持续半天,腹胀,和温柔,导致SBO的工作诊断。
    方法:初始非对比计算机断层扫描(CT)显示SBO没有绞窄的迹象,假设是由MD和伴随的MDB引起的,导致保守的管理。症状持续存在,需要对比增强CT。然而,在非对比CT上观察到的提示MD的扩张肠环在对比增强CT上无法证实.
    方法:使用长管的减压疗法提供了最小的缓解,提示在入院后第5天进行腹腔镜手术,以达到诊断和治疗目的。
    结果:MD切除可有效缓解SBO。组织病理学分析显示一个真正的憩室与异位胰腺组织,确认MD的诊断。在乐队现场,血管和神经结构被包裹在鞘中,与卵黄导管肠系膜的残留物一致;在组织病理学上被诊断为MDB。术后进展顺利,病人在第9天出院,术后。
    结论:基于SBO术前工作诊断的减压治疗和策略性腹腔镜手术取得了良好的结果,强调早期临床怀疑MD和伴随的MDB的重要性,作为SBO的病因。成人MD的影像学变异性和稀有性强调了提高意识和准确诊断以实现最佳管理的必要性。对于怀疑肠缺血的患者应考虑早期干预。然而,该病例强调了在成人MD相关SBO治疗中进行战略规划和采用微创技术的临床意义.
    BACKGROUND: The mesodiverticular band (MDB) of a Meckel\'s diverticulum (MD) is a rare, yet notable etiology of small bowel obstruction (SBO) in adults. Due to the nonspecific symptoms and challenging diagnosis thereof, preoperative clinical suspicion and strategic management are crucial for achieving optimal outcomes. Therefore, we presented a case in which laparoscopic surgery was strategically performed to alleviate ileus, due to a preoperative diagnosis of SBO, suspected to be secondary to an MD with a concomitant MDB.
    METHODS: A 32-year-old male patient presented with a half-day\'s duration of epigastric pain, abdominal distension, and tenderness, resulting in the working diagnosis of SBO.
    METHODS: Initial non-contrast computed tomography (CT) revealed SBO without signs of strangulation, postulated to be caused by an MD and concomitant MDB, resulting in conservative management. The symptoms persisted, necessitating contrast-enhanced CT. However, the dilated bowel loop suggestive of an MD that had been observed on non-contrast CT could not be confirmed on contrast-enhanced CT.
    METHODS: Decompression therapy using a long tube provided minimal relief, prompting laparoscopic surgery on the 5th day post-admission for diagnostic and therapeutic purposes.
    RESULTS: An MD resection effectively relieved the SBO. The histopathological analysis revealed a true diverticulum with ectopic pancreatic tissue, confirming the diagnosis of an MD. At the band site, vascular and neural structures were encased in a sheath, consistent with the remnants of the vitelline duct mesentery; and histopathologically diagnosed as an MDB. The postoperative course was uneventful, and the patient was discharged on the 9th day, postoperatively.
    CONCLUSIONS: Decompression therapy and strategic laparoscopic surgery based on the preoperative working diagnosis of SBO yielded favorable outcomes, highlighting the importance of the early clinical suspicion of an MD and a concomitant MDB, as the etiology of SBO. The imaging variability and rarity of an MD in adults emphasizes the need for a heightened awareness and an accurate diagnosis for optimal management. Early intervention should be deliberated for patients with suspected intestinal ischemia. However, this case accentuates the clinical implications of strategic planning and employing minimally invasive techniques in the management of an MD-related SBO in adults.
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  • 文章类型: Case Reports
    一名11岁的女孩出现了极其罕见的Meckel憩室并发症。患者出现腹胀的主诉,腹痛,食欲下降,和非胆汁性呕吐20天,每个直肠有肿块突出的病史。检查显示直肠检查期间腹部扩张和肠loop突出,类似肠套叠.影像学检查提示肠梗阻。手术探查显示Meckel憩室侵入直肠,伴有密集的肠间粘连。患者接受了Meckel憩室切除术和直肠租金修复。此病例突出了Meckel憩室瘘进入直肠的罕见性。
    An 11-year-old girl presented with an extremely rare complication of Meckel\'s diverticulum. The patient presented with complaints of abdominal distension, abdominal pain, decreased appetite, and non-bilious vomiting for 20 days with a history of mass protruding per rectum. Examination revealed a distended abdomen and prolapsing bowel loops during rectal examination, resembling intussusception. Radiological findings indicated intestinal obstruction. Surgical exploration revealed Meckel\'s diverticulum invading the rectum, accompanied by dense inter-bowel adhesions. The patient underwent resection of Meckel\'s diverticulum and repair of the rectal rent. This case highlights the rarity of Meckel\'s diverticulum fistulating into the rectum.
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  • 文章类型: Journal Article
    Superior mesenteric artery syndrome (SMAS) is a rare cause of duodenal obstruction which is characterized by compression of the duodenum due to narrowing of the space between the superior mesenteric artery and aorta. Incomplete duodenal obstruction due to SMAS in neonates is rarely reported in the literature. In this case, it is a full-term 2-day-old male with the complaint of recurrent vomiting starting soon after birth. The patient was diagnosed with SMAS and duodenoduodenostomy was performed. Accompanying Meckel\'s diverticulum was excised.
    El síndrome de la arteria mesentérica superior (SMAS) es una causa rara de obstrucción duodenal que se caracteriza por la compresión del duodeno debido al estrechamiento del espacio entre la arteria mesentérica superior y la aorta. La obstrucción duodenal incompleta por SMAS en recién nacidos rara vez se informa en la literatura. En este caso se trata de un varón de 2 días nacido a término que presenta vómitos recurrentes desde poco después del nacimiento. El paciente fue diagnosticado de SMAS y se le realizó duodenoduodenostomía. Se extirpó el divertículo de Meckel que lo acompañaba.
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  • 文章类型: Journal Article
    背景:Meckel憩室(MD)是儿童胃肠道出血的重要原因。小肠胶囊内镜(SBCE)是一种应用于不明原因消化道出血患者的一线检查方法,但是关于其在儿童MD中的应用研究很少。本文旨在通过分析SBCE的特点,为儿童MD的辅助诊断提供依据。
    方法:我们回顾性收集疑似MD患者的临床资料。
    结果:本研究共纳入58名儿童。所有58名儿童均出现明显的胃肠道出血(血便或黑便)。胶囊内镜发现2例病灶突出,双腔改变30例(均为MD),7例血管病变,肠黏膜炎性病变3例,3例溃疡或糜烂,12例SBCE无明显异常。对24例患者进行SBCE和tech-99扫描,其中22人根据他们的综合结果被诊断为MD,诊断符合率为91.7%。8例高度怀疑为MD,但tech-99扫描阴性,SBCE阳性。
    结论:SBCE对儿童MD的诊断具有较高的准确性,特别是当与tech-99扫描结合进行时,可以大大提高儿童MD的诊断率。
    BACKGROUND: Meckel diverticulum (MD) is an important cause of gastrointestinal bleeding in children. Small bowel capsule endoscopy (SBCE) is a first-line examination method applied to patients with obscure gastrointestinal bleeding, but there are few studies on its application in children with MD. This article aims to provide evidence in favor of the auxiliary diagnosis of MD in children by analyzing its characteristics using SBCE.
    METHODS: We retrospectively collected the clinical data of patients with suspected MD.
    RESULTS: A total of 58 children were included in this study. All 58 children presented overt gastrointestinal bleeding (bloody stool or melena). Capsule endoscopy identified protruding lesions in 2 cases, double-lumen changes in 30 cases (all considered as MD), vascular lesions in 7 cases, intestinal mucosal inflammatory lesions in 3 cases, ulcers or erosion in 3 cases, and no obvious abnormalities in SBCE in 12 cases. Both SBCE and technetium-99 scans were performed for 24 cases, 22 of which were diagnosed MD by their combined results, giving a diagnostic coincidence rate of 91.7%. Eight cases were highly suspected as MD but were negative for the technetium-99 scan and positive for SBCE.
    CONCLUSIONS: SBCE has high accuracy in the diagnosis of MD in children, especially when performed in combination with a technetium-99 scan, which can greatly improve the diagnostic rate of MD in children.
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  • 文章类型: Journal Article
    目的:异位胰腺,在儿童中不常见的情况,可能面临诊断和治疗挑战。本研究旨在评估儿科患者这种疾病的临床特征和治疗选择。
    方法:我们进行了回顾性分析,包括2000年1月至2022年6月在四家三级医院诊断为异位胰腺的患者。根据临床表现将患者分为有症状组和无症状组。临床参数,包括手术年龄,病变大小和部位,手术或内窥镜入路,病理结果,和结果,进行了统计分析。
    结果:该研究包括88例异位胰腺患者。其中,22有症状,和41岁的年龄在一岁或更小。异位胰腺通常位于Meckel憩室(46.59%),空肠(20.45%),脐部(10.23%),回肠(7.95%),胃(6.82%)。66例患者有伴随疾病。33例患者的异位胰腺位于Meckel憩室,80.49%的病例伴有胃粘膜异位症(GMH)。没有伴有GMH的患者异位胰腺相关症状的患病率更高(75%)。治疗方式包括通过开放手术切除病变,腹腔镜或腹腔镜辅助手术,或根据患者年龄进行内窥镜手术,病变部位和大小,和共存的疾病。
    结论:只有四分之一的异位胰腺患者出现症状。那些位于梅克尔憩室的人通常伴有GMH。开腹手术,由于潜在的并发症,建议腹腔镜手术或内镜下异位胰腺切除术。未来的前瞻性多中心研究有必要建立合理的治疗方案。
    OBJECTIVE: Heterotopic pancreas, an uncommon condition in children, can present with diagnostic and treatment challenges. This study aimed to evaluate the clinical features and treatment options for this disorder in pediatric patients.
    METHODS: We conducted a retrospective analysis, including patients diagnosed with heterotopic pancreas at four tertiary hospitals between January 2000 and June 2022. Patients were categorized into symptomatic and asymptomatic groups based on clinical presentation. Clinical parameters, including age at surgery, lesion size and site, surgical or endoscopic approach, pathological findings, and outcome, were statistically analyzed.
    RESULTS: The study included 88 patients with heterotopic pancreas. Among them, 22 were symptomatic, and 41 were aged one year or younger. The heterotopic pancreas was commonly located in Meckel\'s diverticulum (46.59%), jejunum (20.45%), umbilicus (10.23%),ileum (7.95%), and stomach (6.82%). Sixty-six patients had concomitant diseases. Thirty-three patients had heterotopic pancreas located in the Meckel\'s diverticulum, with 80.49% of cases accompanied by gastric mucosa heterotopia (GMH). Patients without accompanying GMH had a higher prevalence of heterotopic pancreas-related symptoms (75%). Treatment modalities included removal of the lesions by open surgery, laparoscopic or laparoscopic assisted surgery, or endoscopic surgery based on patient\'s age, the lesion site and size, and coexisting diseases.
    CONCLUSIONS: Only one-fourth of the patients with heterotopic pancreas presented with symptoms. Those located in the Meckel\'s diverticulum have commonly accompanying GMH. Open surgical, laparoscopic surgical or endoscopic resection of the heterotopic pancreas is recommended due to potential complications. Future prospective multicenter studies are warranted to establish rational treatment options.
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  • 文章类型: Journal Article
    Meckel憩室[MD),常见的先天性胃肠道异常,在手术过程中偶然遇到的情况会带来两难选择。尽管有历史描述和已知有症状的MD的并发症,切除附带MD(IMD)的决定缺乏明确的指导方针.这项研究旨在通过综合2000年至2023年之间发表的研究证据来评估切除IMD是否合理。影响这一决定的因素,比如人口风险,手术进展和并发症,进行了系统的检查。
    遵循PRISMA2020指南,本综述纳入了42项符合条件的研究,其中包含有关无症状MD治疗结局的数据.研究,既赞成又反对切除,进行了分析。
    考虑到并发症,恶性潜能,和操作安全,风险-收益分析呈现了一幅细微差别的图景。一些作者提出了基于特定标准的条件切除,强调患者的特定因素。在2934例短期和长期并发症分析中,发病率为5.69%。在有死亡率数据的571例病例中,所有5例死亡均归因于原发疾病,而非IMD切除.
    零星的,IMD的不可预测的表现以及原发疾病和患者的变异性使得制定明确的指南具有挑战性。并发症报告的不均匀性强调了标准化分类的必要性。虽然证据的平衡倾向于切除IMD,这项研究承认这一决定的个性化。增加手术和麻醉的安全性,随着对并发症的更好理解和管理,有利于对切除的明智选择,同时考虑到患者特征和原发疾病。
    UNASSIGNED: Meckel Diverticulum [MD), a common congenital anomaly of the gastrointestinal tract, poses a dilemma when incidentally encountered during surgery. Despite historical descriptions and known complications of symptomatic MD, the decision to resect an incidental MD (IMD) lacks clear guidelines. This study aims to assess whether resecting IMDs is justified by synthesizing evidence from studies published between 2000 and 2023. Factors influencing this decision, such as demographic risks, surgical advancements and complications, are systematically examined.
    UNASSIGNED: Following the PRISMA 2020 guidelines, this review incorporates 42 eligible studies with data on outcomes of asymptomatic MD management. Studies, both favoring and opposing resection, were analyzed.
    UNASSIGNED: Considering complications, malignancy potential, and operative safety, the risk-benefit analysis presents a nuanced picture. Some authors propose conditional resection based on specific criteria, emphasizing patient-specific factors. Of 2934 cases analyzed for short- and long-term complications, the morbidity rate was 5.69%. Of 571 cases where mortality data were available, all 5 fatalities were attributed to the primary disease rather than IMD resection.
    UNASSIGNED: The sporadic, unpredictable presentation of IMD and the variability of both the primary disease and the patient make formulation of definitive guidelines challenging. The non-uniformity of complications reporting underscores the need for standardized categorization. While the balance of evidence leans towards resection of IMDs, this study acknowledges the individualized nature of this decision. Increased safety in surgery and anesthesia, along with better understanding and management of complications favor a judicious preference for resection, while taking into account patient characteristics and the primary disease.
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  • 文章类型: Case Reports
    Meckel憩室是最常见的先天性胃肠道缺陷,患病率为2%。它大多无症状,很少引起成人急腹症。在这个案例报告中,一名28岁男性,以前没有腹部手术,出现小肠梗阻的临床症状。手术显示Meckel憩室粘附在腹壁上,导致腹内疝合并小肠梗阻.憩室开放切除,无术后并发症发生。腹腔镜检查似乎很安全,建议手术切除有症状的Meckel憩室。
    Meckel\'s diverticulum is the most common congenital gastrointestinal defect with a prevalence of 2%. It is mostly asymptomatic and it rarely causes acute abdomen in adults. In this case report, a 28-year-old male with no previous abdominal surgery presented with clinical symptoms of small bowel obstruction. Surgery revealed a Meckel\'s diverticulum adherent to the abdominal wall, causing internal herniation with small bowel obstruction. The diverticulum was openly resected and no post-operative complications occurred. Laparoscopy seems safe, and surgical removal of the symptomatic Meckel\'s diverticulum is recommended.
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  • 文章类型: Case Reports
    Meckel憩室是妊娠期间卵黄管不完全闭塞引起的胃肠道最常见的先天性变异。在大多数情况下,个体是无症状的。这是一例38岁的便血患者,诊断为Meckel憩室。在憩室内发现了肿块。组织病理学和免疫组织化学研究显示分化良好的神经内分泌肿瘤。Meckel憩室肿瘤的发展是罕见的,当被识别时,这些肿瘤中只有0.5%-3.2%被发现是恶性的。此外,消化道出血是神经内分泌肿瘤少见的临床特征。这种情况的独特之处在于,许多影像学研究和内窥镜程序无法明确确定Meckle憩室和潜在的神经内分泌肿瘤的存在。通过高度的临床怀疑和与外科同事的合作,进行了剖腹探查术,最终导致了潜在病理的鉴定和诊断。
    Meckel diverticulum is the most common congenital variation of the gastrointestinal tract arising from incomplete obliteration of the vitelline duct during gestation. In most cases, individuals are asymptomatic. This is a case of a 38-year-old patient with hematochezia in whom Meckel diverticulum was diagnosed. A mass was identified within the diverticulum. Histopathological and immunohistochemical studies revealed a well-differentiated neuroendocrine tumor. The development of tumors in Meckel diverticulum is rare, and when identified, only 0.5%-3.2% of these tumors are found to be malignant. Furthermore, gastrointestinal bleeding is an infrequent clinical feature of neuroendocrine tumors. A unique aspect of this case was that numerous imaging studies and endoscopic procedures were unable to definitively identify the presence of Meckle diverticulum and underlying neuroendocrine tumor. Through a high clinical suspicion and collaboration with surgical colleagues, an exploratory laparotomy was performed, which ultimately led to the identification and diagnosis of the underlying pathology.
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