Meckel Diverticulum

Meckel 憩室
  • 文章类型: Journal Article
    背景:Meckel憩室(MD)的中关节带(MDB)是一种罕见的,然而,成人小肠梗阻(SBO)的显着病因。由于非特异性症状和具有挑战性的诊断,术前临床怀疑和战略管理对于获得最佳结果至关重要.因此,我们提出了一个病例,其中有策略地进行腹腔镜手术以减轻肠梗阻,由于SBO的术前诊断,怀疑是继发于伴有MDB的MD。
    方法:一名32岁男性患者表现为上腹痛持续半天,腹胀,和温柔,导致SBO的工作诊断。
    方法:初始非对比计算机断层扫描(CT)显示SBO没有绞窄的迹象,假设是由MD和伴随的MDB引起的,导致保守的管理。症状持续存在,需要对比增强CT。然而,在非对比CT上观察到的提示MD的扩张肠环在对比增强CT上无法证实.
    方法:使用长管的减压疗法提供了最小的缓解,提示在入院后第5天进行腹腔镜手术,以达到诊断和治疗目的。
    结果:MD切除可有效缓解SBO。组织病理学分析显示一个真正的憩室与异位胰腺组织,确认MD的诊断。在乐队现场,血管和神经结构被包裹在鞘中,与卵黄导管肠系膜的残留物一致;在组织病理学上被诊断为MDB。术后进展顺利,病人在第9天出院,术后。
    结论:基于SBO术前工作诊断的减压治疗和策略性腹腔镜手术取得了良好的结果,强调早期临床怀疑MD和伴随的MDB的重要性,作为SBO的病因。成人MD的影像学变异性和稀有性强调了提高意识和准确诊断以实现最佳管理的必要性。对于怀疑肠缺血的患者应考虑早期干预。然而,该病例强调了在成人MD相关SBO治疗中进行战略规划和采用微创技术的临床意义.
    BACKGROUND: The mesodiverticular band (MDB) of a Meckel\'s diverticulum (MD) is a rare, yet notable etiology of small bowel obstruction (SBO) in adults. Due to the nonspecific symptoms and challenging diagnosis thereof, preoperative clinical suspicion and strategic management are crucial for achieving optimal outcomes. Therefore, we presented a case in which laparoscopic surgery was strategically performed to alleviate ileus, due to a preoperative diagnosis of SBO, suspected to be secondary to an MD with a concomitant MDB.
    METHODS: A 32-year-old male patient presented with a half-day\'s duration of epigastric pain, abdominal distension, and tenderness, resulting in the working diagnosis of SBO.
    METHODS: Initial non-contrast computed tomography (CT) revealed SBO without signs of strangulation, postulated to be caused by an MD and concomitant MDB, resulting in conservative management. The symptoms persisted, necessitating contrast-enhanced CT. However, the dilated bowel loop suggestive of an MD that had been observed on non-contrast CT could not be confirmed on contrast-enhanced CT.
    METHODS: Decompression therapy using a long tube provided minimal relief, prompting laparoscopic surgery on the 5th day post-admission for diagnostic and therapeutic purposes.
    RESULTS: An MD resection effectively relieved the SBO. The histopathological analysis revealed a true diverticulum with ectopic pancreatic tissue, confirming the diagnosis of an MD. At the band site, vascular and neural structures were encased in a sheath, consistent with the remnants of the vitelline duct mesentery; and histopathologically diagnosed as an MDB. The postoperative course was uneventful, and the patient was discharged on the 9th day, postoperatively.
    CONCLUSIONS: Decompression therapy and strategic laparoscopic surgery based on the preoperative working diagnosis of SBO yielded favorable outcomes, highlighting the importance of the early clinical suspicion of an MD and a concomitant MDB, as the etiology of SBO. The imaging variability and rarity of an MD in adults emphasizes the need for a heightened awareness and an accurate diagnosis for optimal management. Early intervention should be deliberated for patients with suspected intestinal ischemia. However, this case accentuates the clinical implications of strategic planning and employing minimally invasive techniques in the management of an MD-related SBO in adults.
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  • 文章类型: Journal Article
    Superior mesenteric artery syndrome (SMAS) is a rare cause of duodenal obstruction which is characterized by compression of the duodenum due to narrowing of the space between the superior mesenteric artery and aorta. Incomplete duodenal obstruction due to SMAS in neonates is rarely reported in the literature. In this case, it is a full-term 2-day-old male with the complaint of recurrent vomiting starting soon after birth. The patient was diagnosed with SMAS and duodenoduodenostomy was performed. Accompanying Meckel\'s diverticulum was excised.
    El síndrome de la arteria mesentérica superior (SMAS) es una causa rara de obstrucción duodenal que se caracteriza por la compresión del duodeno debido al estrechamiento del espacio entre la arteria mesentérica superior y la aorta. La obstrucción duodenal incompleta por SMAS en recién nacidos rara vez se informa en la literatura. En este caso se trata de un varón de 2 días nacido a término que presenta vómitos recurrentes desde poco después del nacimiento. El paciente fue diagnosticado de SMAS y se le realizó duodenoduodenostomía. Se extirpó el divertículo de Meckel que lo acompañaba.
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  • 文章类型: Journal Article
    Meckel憩室[MD),常见的先天性胃肠道异常,在手术过程中偶然遇到的情况会带来两难选择。尽管有历史描述和已知有症状的MD的并发症,切除附带MD(IMD)的决定缺乏明确的指导方针.这项研究旨在通过综合2000年至2023年之间发表的研究证据来评估切除IMD是否合理。影响这一决定的因素,比如人口风险,手术进展和并发症,进行了系统的检查。
    遵循PRISMA2020指南,本综述纳入了42项符合条件的研究,其中包含有关无症状MD治疗结局的数据.研究,既赞成又反对切除,进行了分析。
    考虑到并发症,恶性潜能,和操作安全,风险-收益分析呈现了一幅细微差别的图景。一些作者提出了基于特定标准的条件切除,强调患者的特定因素。在2934例短期和长期并发症分析中,发病率为5.69%。在有死亡率数据的571例病例中,所有5例死亡均归因于原发疾病,而非IMD切除.
    零星的,IMD的不可预测的表现以及原发疾病和患者的变异性使得制定明确的指南具有挑战性。并发症报告的不均匀性强调了标准化分类的必要性。虽然证据的平衡倾向于切除IMD,这项研究承认这一决定的个性化。增加手术和麻醉的安全性,随着对并发症的更好理解和管理,有利于对切除的明智选择,同时考虑到患者特征和原发疾病。
    UNASSIGNED: Meckel Diverticulum [MD), a common congenital anomaly of the gastrointestinal tract, poses a dilemma when incidentally encountered during surgery. Despite historical descriptions and known complications of symptomatic MD, the decision to resect an incidental MD (IMD) lacks clear guidelines. This study aims to assess whether resecting IMDs is justified by synthesizing evidence from studies published between 2000 and 2023. Factors influencing this decision, such as demographic risks, surgical advancements and complications, are systematically examined.
    UNASSIGNED: Following the PRISMA 2020 guidelines, this review incorporates 42 eligible studies with data on outcomes of asymptomatic MD management. Studies, both favoring and opposing resection, were analyzed.
    UNASSIGNED: Considering complications, malignancy potential, and operative safety, the risk-benefit analysis presents a nuanced picture. Some authors propose conditional resection based on specific criteria, emphasizing patient-specific factors. Of 2934 cases analyzed for short- and long-term complications, the morbidity rate was 5.69%. Of 571 cases where mortality data were available, all 5 fatalities were attributed to the primary disease rather than IMD resection.
    UNASSIGNED: The sporadic, unpredictable presentation of IMD and the variability of both the primary disease and the patient make formulation of definitive guidelines challenging. The non-uniformity of complications reporting underscores the need for standardized categorization. While the balance of evidence leans towards resection of IMDs, this study acknowledges the individualized nature of this decision. Increased safety in surgery and anesthesia, along with better understanding and management of complications favor a judicious preference for resection, while taking into account patient characteristics and the primary disease.
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  • 文章类型: Case Reports
    背景:黄石是Meckel憩室并发症的已知原因。我们介绍了一例Meckel憩室中的牛黄导致肠梗阻的病例。此外,我们进行了叙述性审查,以探讨Meckel憩室和牛黄之间的关系。
    方法:我们介绍了一例22岁的患者,因肠梗阻持续三天和脐周压痛而入院。腹部CT断层扫描显示直径为2厘米的高密度圆形结构,小肠扩张41毫米,和自由流体。在手术探查期间,在小肠的肠系膜边缘和脐后壁之间发现了Meckel憩室。Meckel憩室被切除,经检查,它被发现含有钙化的植物黄。术后病程顺利。
    结论:Meckel憩室中的结石的临床和旁表现是非特异性的,尽管诊断方式得到了改进,但诊断仍然具有挑战性。在手术过程中,经常发现梅克尔憩室和牛黄之间的关联,因为使用CT扫描很难诊断。腹腔镜手术和开腹手术的选择取决于患者的情况。
    结论:诊断Meckel憩室中的牛黄仍然具有挑战性。治疗包括手术,手术方式的选择取决于具体情况。
    BACKGROUND: Bezoars are a known cause of complications in Meckel\'s diverticulum. We present a case in which a bezoar in a Meckel\'s diverticulum resulted in intestinal obstruction. In addition, we conducted a narrative review to explore the association between Meckel\'s diverticulum and bezoars.
    METHODS: We present the case of a 22-year-old patient admitted for bowel obstruction persisting for three days and periumbilical tenderness. Abdominal CT tomography revealed a hyper dense circular structure with a diameter of 2 cm, small bowel distension of 41 mm, and free fluid. During surgical exploration, a Meckel diverticulum was found between the antimesenteric border of the small bowel and posterior wall of the umbilicus. The Meckel diverticulum was resected, and upon examination, it was found to contain a calcified phytobezoar. The postoperative course was uneventful.
    CONCLUSIONS: The clinical and paraclinical presentation of bezoars in Meckel\'s diverticulum is nonspecific and diagnosis remains challenging despite improved diagnostic modalities. The association between Meckel\'s diverticulum and bezoars is often identified during surgery, as it is difficult to diagnose using CT scans. The choice between laparoscopic and open surgery depends on the patient\'s situation.
    CONCLUSIONS: Diagnosing a bezoar in a Meckel\'s diverticulum remains challenging. Treatment involves surgery, and the choice of surgical approach depends on the context.
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  • 文章类型: Meta-Analysis
    目的:Meckel憩室(MD)是一种常见的消化道畸形,常伴有严重并发症。寻找安全有效的诊断方法对筛查MD具有重要意义。这项研究的目的是评估a99m(Tc-99m)扫描对小儿出血MD的有效性。
    方法:作者对发表在PubMed上的研究进行了系统综述,Embase,和WebofScience在2023年1月1日之前。本系统综述包括基于PICOS的研究。流程图由PRISMA软件制作。通过RevMan5软件(QUADAS-2:诊断准确性研究质量评估-2)评估纳入研究的质量。敏感性,特异性,和其他准确性测量值使用Stata/SE12.0软件进行汇总。
    结果:本系统综述纳入了16项研究,共1115名儿童。由于显著的异质性,使用随机效应模型进行荟萃分析。合并的敏感性和特异性分别为0.80[置信区间(95%CI,0.73-0.86)和0.95(95%CI,0.86-0.98)]。分别。曲线下面积(AUC)为0.88(95%CI,0.85-0.90)。观察到发表偏倚(Begg检验p=0.053)。
    结论:Tc-99m扫描具有较高的特异性,但适度的敏感性,这总是受到一些因素的影响。因此,Tc-99m扫描在诊断小儿出血MD方面有一定的局限性.
    Meckel diverticulum (MD) is a common malformation of the digestive tract, often accompanied by serious complications. It is important to find safe and effective diagnostic methods for screening MD. The aim of this study was to evaluate the effectiveness of a technetium-99m (Tc-99m) scan for pediatric bleeding MD.
    The authors conducted a systematic review of studies published in PubMed, Embase, and Web of Science before 1 January 2023. Studies based on PICOS were included in this systematic review. The flow chart was made by PRISMA software. The quality of included studies was assessed by RevMan5 software (QUADAS-2: Quality Assessment of Diagnostic Accuracy Studies-2). The sensitivity, specificity, and other measurements of accuracy were pooled using Stata/SE 12.0 software.
    Sixteen studies with 1115 children were included in this systematic review. A randomized-effects model was used for the meta-analysis because of significant heterogeneity. The combined sensitivity and specificity were 0.80 [Confidence Interval (95% CI, 0.73-0.86) and 0.95 (95% CI, 0.86-0.98)], respectively. The area under the curve (AUC) was 0.88 (95% CI, 0.85-0.90). Publication bias (Begg\'s test p = 0.053) was observed.
    Tc-99m scan has high specificity, but moderate sensitivity, which is always influenced by some factors. Hence, the Tc-99m scan has some limitations in the diagnosis of pediatric bleeding MD.
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  • Meckel憩室是最常见的胃肠道异常。它起因于脐肠管的不完全闭合,这是一个真正的憩室在回肠的肠系膜边缘。尽管大多数患者无症状,它们可以出现炎症,出血,肠套叠,肠梗阻,和穿孔,除其他外;这是急腹症的重要鉴别诊断。一名19岁女性因间歇性弥漫性腹痛两个月而求医,恶心,和腹泻。在要求的成像测试中,断层摄影术,和小肠造影术,建议诊断为Meckel憩室伴一定程度的肠套叠。患者接受择期手术治疗,无并发症,术后第二天出院,临床好转。在本节中,我们会检讨过去五年发表的类似个案的刊物。
    Meckel\'s diverticulum is the most common gastrointestinal tract anomaly. It arises from the incomplete closure of the omphalomesenteric conduit, which is a true diverticulum at the antimesenteric border of the ileum. Although the majority of patients are asymptomatic, they can present with inflammation, hemorrhage, intussusception, intestinal obstruction, and perforation, among others; this constitutes an important differential diagnosis for acute abdomen. A 19-year-old female sought medical attention because of intermittent diffuse abdominal pain for two months, nausea, and diarrhea. In the requested imaging tests, tomography, and enterotomography, a diagnosis of Meckel\'s diverticulum with some degree of intussusception was suggested. The patient underwent elective surgical treatment without complications and was discharged on the second postoperative day with clinical improvement. In this section, we review publications on similar cases published in the last five years.
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  • 文章类型: Journal Article
    回肠环是影响胃肠道的大多数先天性异常的解剖位置。这些包括Meckel憩室,回肠重复,发育不全,闭锁,粘膜隔膜,和回肠错位。通常表现为腹痛的症状性病变,肠梗阻或出血通常在婴儿期和儿童期进行诊断和治疗。然而,这些先天性疾病中的许多可能在临床上保持沉默,并在因无关医学原因接受放射学评估的成人中偶然发现.本文介绍了先天性回肠异常的频谱及其在小肠检查和腹部CT上的独特特征。
    The ileal loops are anatomical location for the majority of congenital anomalies affecting the gastrointestinal tract. These include Meckel\'s diverticulum, ileal duplication, dysgenesis, atresia, mucosal diaphragm, and malposition of the ileum. Symptomatic lesions that often present with abdominal pain, intestinal obstruction or bleeding are usually diagnosed and treated during infancy and childhood. However, many of these congenital conditions may remain clinically silent and detected incidentally in adults undergoing radiological evaluation for unrelated medical reasons. This article presents the spectrum of the congenital ileal anomalies and their distinct features on small bowel examination and CT of the abdomen.
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  • 文章类型: Review
    UNASSIGNED:Meckel憩室是不完全闭塞和脐肠管消退的结果,是最常见的先天性肠道畸形。许多Meckel憩室仍然无症状,并被发现为偶然发现。他们提出了诊断挑战。
    未经证实:我们报告一例35岁男性,表现为急腹症和肠梗阻。腹部计算机断层扫描显示机械性小肠肠梗阻。回肠末端有一个口径跳跃,直径近2厘米的圆形腔内可定义的高密度结构。
    UNASSIGNED:进行了探查性腹腔镜检查,发现Meckel憩室发炎,肠石受累是肠梗阻的原因。
    未经证实:有症状的Meckel憩室,出血和梗阻是最常见的并发症.由于Meckel的憩室和肠石引起的肠梗阻的发展被认为极为罕见,但应考虑在内。
    UNASSIGNED: Meckel\'s diverticula result from incomplete obliteration and regression of the omphaloenteric duct and are the most common congenital intestinal malformations. Many Meckel\'s diverticula remain asymptomatic and are discovered as incidental findings. They present a diagnostic challenge.
    UNASSIGNED: We report the case of a 35-year-old man who presented with an acute abdomen and ileus. Computed tomography of the abdomen showed a mechanical small bowel ileus. There was a calibre jump in the terminal ileum with a round endoluminal definable hyperdense structure of almost 2 cm in diameter.
    UNASSIGNED: An exploratory laparoscopy was performed revealing an inflamed Meckel\'s diverticulum with impacted enterolith as the cause of the intestinal obstruction.
    UNASSIGNED: In symptomatic Meckel\'s diverticula, haemorrhage and obstruction are the most common complications. The development of ileus due to a Meckel\'s diverticulum with an enterolith is considered extremely rare but should be taken into account.
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  • 文章类型: Case Reports
    未经证实:诊断胰腺异位症(PH)具有挑战性,因为这是一种罕见的先天性异常。我们报告了一例66岁的男子,该男子使用单气囊小肠镜检查诊断为肠梗阻和空肠PH。回顾178例小肠PH文献显示:(1)PH多发生在十二指肠(61.8%),其次是空肠(22.5%)和回肠(14.6%);(2)回肠PH患者年轻(平均,40.7vs54.6年;P<0.001),而空肠PH患者年龄较大(平均,59.5vs51.7年;P=0.006);(3)空肠PH患者大多数为女性,而十二指肠或回肠PH患者主要为男性(M:F=0.8:1vs2.5:1;P=0.003);(4)无症状病例很少见(小肠和非小肠为15.2%vs83.4%,分别);(5)大多数回肠PH患者出现出血(61.5%),其余患者为腹痛(42.8%);(6)急诊手术11例(6.2%),主要位于空肠(12.5%)和Meckel憩室(25%);(7)海因里希的分类可能尚无定论。肠镜检查仅有6例(3.4%),早期诊断和进一步的微创手术可以通过肠镜检查实现。
    Diagnosing pancreatic heterotopia (PH) is challenging, because it is a rare congenital anomaly. We report the case of a 66-year-old man who presented with ileus and jejunal PH diagnosed using single-balloon enteroscopy. Reviewing 178 cases of small intestinal PH in the literature showed that (1) PH mostly occurred at the duodenum (61.8%), followed by the jejunum (22.5%) and ileum (14.6%); (2) patients with ileal PH were younger (mean, 40.7 vs 54.6 years; P < 0.001), while those with jejunal PH were older (mean, 59.5 vs 51.7 years; P = 0.006); (3) most patients with jejunal PH were females, while those with duodenal or ileal PH were predominantly males (M:F = 0.8:1 vs 2.5:1; P = 0.003); (4) asymptomatic cases were rare (15.2% vs 83.4% in small and nonsmall bowel, respectively); (5) most patients with ileal PH presented with bleeding (61.5%), while the remaining had abdominal pain (42.8%); (6) emergent operation was performed in 11 cases (6.2%), mainly at the jejunum (12.5%) and Meckel\'s diverticulum (25%); and (7) Heinrich\'s classification may be inconclusive. Enteroscopy was performed in only 6 cases (3.4%), and earlier diagnosis and further minimally invasive procedures could have been achieved with enteroscopy.
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  • 文章类型: Journal Article
    Meckel憩室(MD)是许多已知的先天性肠畸形之一。在大约2%的人口中可以看到。纤维瘤是不常见的。它们是独一无二的,分化良好,和快速生长的肌腱膜纤维瘤病肿瘤,考虑为1级纤维肉瘤。他们为外科医生提供独家管理挑战。纤维瘤最常见的表现是无痛性肿块,生长缓慢。很少,它们可能表现为肠梗阻,导致手术急症。我们介绍了迄今为止历史上唯一的病例,并回顾了一位65岁的绅士的相关文献,他向我们展示了肠梗阻的特征,他成功地进行了包含MD的回肠选择性节段切除术,并伴有硬纤维瘤。需要一个由肿瘤外科医生组成的团队来解决这类疾病的多模态方法,专家,和放射肿瘤学家设计一个标准的治疗方案。
    Meckel\'s diverticulum (MD) is among the many known congenital malformations of intestine. It is seen in approximately 2% of the population. Desmoid tumors are unusual. They are unique, well-differentiated, and fast-growing musculoaponeurotic fibromatosis tumors, contemplated as Grade 1 fibro sarcoma. They offer exclusive management challenges to surgeons. The most common presentation of desmoid tumors is of painless masses with sluggish growth. Rarely, they may present as intestinal obstruction leading to surgical emergency. We present the only case in history till date along with review of the relevant literature of a 65-year-old gentleman who presented to us with features of intestinal obstruction who successfully underwent elective segmental resection of ileum containing MD with its desmoid tumor. A multimodality approach is needed to tackle such kind of diseases with a team comprising oncosurgeons, oncophysicians, and radiation oncologist to design a standard treatment protocol.
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