Mesh : Humans Meckel Diverticulum / complications diagnostic imaging diagnosis Capsule Endoscopy / methods Male Female Retrospective Studies Child Child, Preschool Gastrointestinal Hemorrhage / etiology Adolescent Infant Intestine, Small / diagnostic imaging pathology Predictive Value of Tests Radionuclide Imaging Radiopharmaceuticals

来  源:   DOI:10.1097/MEG.0000000000002783   PDF(Pubmed)

Abstract:
BACKGROUND: Meckel diverticulum (MD) is an important cause of gastrointestinal bleeding in children. Small bowel capsule endoscopy (SBCE) is a first-line examination method applied to patients with obscure gastrointestinal bleeding, but there are few studies on its application in children with MD. This article aims to provide evidence in favor of the auxiliary diagnosis of MD in children by analyzing its characteristics using SBCE.
METHODS: We retrospectively collected the clinical data of patients with suspected MD.
RESULTS: A total of 58 children were included in this study. All 58 children presented overt gastrointestinal bleeding (bloody stool or melena). Capsule endoscopy identified protruding lesions in 2 cases, double-lumen changes in 30 cases (all considered as MD), vascular lesions in 7 cases, intestinal mucosal inflammatory lesions in 3 cases, ulcers or erosion in 3 cases, and no obvious abnormalities in SBCE in 12 cases. Both SBCE and technetium-99 scans were performed for 24 cases, 22 of which were diagnosed MD by their combined results, giving a diagnostic coincidence rate of 91.7%. Eight cases were highly suspected as MD but were negative for the technetium-99 scan and positive for SBCE.
CONCLUSIONS: SBCE has high accuracy in the diagnosis of MD in children, especially when performed in combination with a technetium-99 scan, which can greatly improve the diagnostic rate of MD in children.
摘要:
背景:Meckel憩室(MD)是儿童胃肠道出血的重要原因。小肠胶囊内镜(SBCE)是一种应用于不明原因消化道出血患者的一线检查方法,但是关于其在儿童MD中的应用研究很少。本文旨在通过分析SBCE的特点,为儿童MD的辅助诊断提供依据。
方法:我们回顾性收集疑似MD患者的临床资料。
结果:本研究共纳入58名儿童。所有58名儿童均出现明显的胃肠道出血(血便或黑便)。胶囊内镜发现2例病灶突出,双腔改变30例(均为MD),7例血管病变,肠黏膜炎性病变3例,3例溃疡或糜烂,12例SBCE无明显异常。对24例患者进行SBCE和tech-99扫描,其中22人根据他们的综合结果被诊断为MD,诊断符合率为91.7%。8例高度怀疑为MD,但tech-99扫描阴性,SBCE阳性。
结论:SBCE对儿童MD的诊断具有较高的准确性,特别是当与tech-99扫描结合进行时,可以大大提高儿童MD的诊断率。
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