■低剂量计算机断层扫描(CT)已越来越多地用于肺癌筛查。孤立性肺结节(SPN)的定位对于切除至关重要。两阶段定位方法涉及放射科医师在手术前注射染料。定位和切除之间的显著间隔与标记物失败的较高风险相关,心理困扰和手术并发症。全身麻醉下的单阶段定位和切除程序提出了独特的挑战。这项研究的目的是比较安全性,两种方法的疗效和患者满意度。
■这是一项回顾性研究,比较了SPN的两阶段和单阶段术前定位的结果。主要研究结果是总手术时间。次要结果包括成功的病变定位,并发症发生率,重新接纳30天,死亡率,患者满意度,和疼痛程度。
■单阶段组和两阶段组分别包括26例和56例患者。单级臂的总手术时间(平均:188分钟)明显长于两级臂(平均:172分钟,P<0.001),这是由于术中定位所需的额外时间。单阶段组的平均满意度得分明显高于两阶段组(92vs.52.69,P=0.004)。与两级手臂相比,单级手臂通过数字评定量表评估的疼痛水平更好(平均值:8.8vs.4.85,P=0.007)。
■单阶段定位和切除导致总手术时间略有增加,患者满意度更高,疼痛更少,安全性和有效性与常规两阶段方法相当。
UNASSIGNED: Low-dose computed tomography (CT) has been increasingly utilized for lung cancer screening.
Localization of solitary pulmonary nodules (SPN) is crucial for resection. Two-stage
localization method involves dye injection by radiologists prior to the operation. The significant interval between
localization and resection is associated with a higher risk of marker failure, psychological distress and procedural complications. Single-stage
localization and resection procedure under general anesthesia poses unique challenges. The aim of the study is to compare the safety, efficacy and patient satisfaction between the two methods.
UNASSIGNED: This is a retrospective study comparing outcomes between two-stage and single-stage pre-operative localization of SPN. The primary study outcome was total operating time. Secondary outcomes included successful lesion localization, complication rate, 30-day readmission, mortality, patient satisfaction, and pain level.
UNASSIGNED: A total of 26 and 56 patients were included for the single and two-stage group respectively. Total operative time was significantly longer in the single-stage arm (mean: 188 min) than that of the two-stage arm (mean: 172 min, P<0.001) due to the additional time needed for intra-operative localization. Mean satisfaction score was significantly higher in the single-stage group than that of the two-stage group (92 vs. 52.69, P=0.004). Pain level assessed by numerical rating scales was better in the single-stage arm compared to the two-stage arm (mean: 8.8 vs. 4.85, P=0.007).
UNASSIGNED: Single-stage
localization and resection resulted in a minor increase in total operative time, higher patient satisfaction and less pain with comparable safety and efficacy to conventional two-stage approach.