关键词: bone distribution pattern knee localization musculoskeletal tumor pediatric cancer sarcoma soft tissue

来  源:   DOI:10.3390/jcm13154405   PDF(Pubmed)

Abstract:
Background: The diagnostic work-up of musculoskeletal tumors is a multifactorial process. During the early phase, differential diagnoses are made using basic radiological imaging. In this phase, part of the decision making is based on the patient\'s age, as well as the incidence and predilection sites of different entities. Unfortunately, this information is based on older and fragmented data. In this study, we retrospectively evaluated all soft-tissue and bone tumors around the knee in children treated at our tertiary center in the last 20 years, with the aim of verifying the data used today. Methods: In this retrospective study, the databank of our tertiary center was used to give an overview of treated tumors around the knee in children. Results: We were able to include 224 children with bone and soft-tissue tumors around the knee. The cohort consisted of 184 bone tumors, of which 144 were benign and 40 malignant. The 40 soft-tissue tumors comprised 30 benign and 10 malignant masses. The most common lesions were osteochondromas (88) in the bone and tenosynovial giant-cell tumors (12) in the soft tissue. Conclusions: With this original work, we were able to verify and supplement earlier studies, as well as deepen our insight into these very rare diseases.
摘要:
背景:肌肉骨骼肿瘤的诊断工作是一个多因素的过程。在早期阶段,使用基本的放射学成像进行鉴别诊断。在这个阶段,决策的一部分是基于患者的年龄,以及不同实体的发生率和好发部位。不幸的是,此信息基于较旧和零散的数据。在这项研究中,我们回顾性评估了过去20年在我们的三级中心接受治疗的儿童膝关节周围的所有软组织和骨肿瘤,目的是验证今天使用的数据。方法:在这项回顾性研究中,我们三级中心的数据库用于概述儿童膝关节周围的治疗肿瘤.结果:我们能够包括224名患有膝关节周围骨和软组织肿瘤的儿童。该队列包括184个骨肿瘤,其中良性144例,恶性40例。40个软组织肿瘤包括30个良性肿块和10个恶性肿块。最常见的病变是骨骼中的骨软骨瘤(88)和软组织中的腱鞘巨细胞瘤(12)。结论:通过这项原创作品,我们能够验证和补充早期的研究,以及加深我们对这些非常罕见的疾病的了解。
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