L10

  • 文章类型: Journal Article
    2008年世界危机之后,有人认为经济复苏还不够充分。在这种情况下,在过去的十年中,关于滞后,特别是投资滞后的争论有所增加。这项研究的目的是分析土耳其经济中的投资滞后和滞后的基本动态。结构断裂测试用于识别滞后。传统和非对称因果关系检验用于识别滞后的基本动力学。投资,GDP,利率,和生产率变量用于分析投资滞后。对变量进行了结构断裂测试,而传统的和不对称的因果关系检验适用于投资及其决定因素之间。结构断裂试验证明了滞后性的存在。根据格兰杰因果关系检验,利率没有因果关系,GDP和生产率对投资的影响。利率对投资没有影响的事实证明了滞后性。根据不对称因果关系检验,利率和投资之间没有关系。GDP和投资之间存在反向关系。生产率和投资之间存在不对称关系。生产率冲击对投资造成不对称影响的事实使生产率冲击成为滞后的主要动力。此外,有大量证据表明,全要素生产率的强滞后性和高不确定性加剧了投资滞后性。因此,在制定滞后政策时应考虑生产率冲击。
    After the 2008 World Crisis, there is a view that the economic recovery has not been adequate. In this context, the debate on hysteresis and especially investment hysteresis has increased in the last decade. The aim of this study is to analyze the investment hysteresis and the basic dynamics of hysteresis in the Turkish economy. Structural break tests are used to identify hysteresis. Traditional and asymmetric causality tests are used to identify the fundamental dynamics of hysteresis. Investment, GDP, interest rate, and productivity variables are used to analyze investment hysteresis. Structural break tests were applied to the variables, while conventional and asymmetric causality tests were applied between investments and their determinants. Structural break tests prove the existence of hysteresis. According to the Granger causality test, there is no causality from interest rates, GDP and productivity to investments. The fact that interest rates have no effect on investments proves hysteresis. According to the asymmetric causality test, there is no relationship between interest rates and investments. There is an inverse relationship between GDP and investments. There is an asymmetric relationship between productivity and investments. The fact that productivity shocks cause asymmetric effects on investments makes productivity shocks the main dynamic of hysteresis. In addition, there is considerable evidence that the strong hysteresis and high uncertainty of TFP exacerbate investment hysteresis. Therefore, productivity shocks should be taken into account in policymaking for hysteresis.
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  • 文章类型: Journal Article
    使用TB-Annotator软件对来自超过100,000个结核分枝杆菌复合体基因组的基因组测序数据进行分析,揭示了以前未知的谱系,提议的名字L10,在非洲中部。系统发育重建表明L10可能代表非洲分枝杆菌进化和地理迁移历史中的缺失环节。
    Analysis of genome sequencing data from >100,000 genomes of Mycobacterium tuberculosis complex using TB-Annotator software revealed a previously unknown lineage, proposed name L10, in central Africa. Phylogenetic reconstruction suggests L10 could represent a missing link in the evolutionary and geographic migration histories of M. africanum.
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  • 文章类型: Journal Article
    战略重点是通过加强医疗器械企业的组织能力来确保其竞争力,which,反过来,确保其不断发展。本研究旨在调查管理策略和组织文化,这可能会影响这些公司的业绩,并分析了教育培训投资的影响。
    我们使用了韩国职业教育和培训研究所进行的第3至第6次人力资本企业小组调查的数据,以及韩国信息服务局的数据,并对6,112名工人和260家公司进行了分析。为了分析,将管理策略和组织文化设置为自变量,公司绩效被设定为因变量。此外,教育和培训投资被设置为自变量和因变量之间的控制变量。将企业绩效分为组织满意度和组织承诺进行分析。
    差异化战略和创新文化对组织满意度有积极的(+)影响,而成本领先战略和等级文化有负面的(-)效应。另一方面,在与教育和培训投资互动的情况下,成本领先战略和等级文化产生了积极的(+)效应,而差异化战略和创新文化具有负(-)效应。在组织承诺中,创新文化产生了积极的(+)效应,等级文化有负面的(-)效应。在与教育和培训投资互动的情况下,只有等级文化有积极的(+)效应。
    创新文化对医疗器械企业的业绩产生了积极影响。此外,成本领先战略,等级文化,教育和培训投资提高了这些公司的公司绩效。为了提高公司绩效,这些公司应创建创新文化,并根据组织文化投资于教育和培训。
    COVID-19证明了韩国医疗设备的卓越,而医疗器械行业由于慢性病和非面对面治疗的增加,预计将继续保持增长。然而,当前的医疗器械行业被拥有资本和技术实力的全球公司所垄断。为了克服这一点,韩国医疗设备公司正在开发以初创企业为中心的创新医疗设备,但是现在是时候对它们做出战略性回应,以便与全球公司竞争。总的来说,公司通过基于市场环境分析威胁和机会来建立生存和成长的管理策略,以根据市场竞争维持最佳组织,政府政策,以及消费者需求的变化。战略通常是基于组成公司的组织的文化而制定的。当谈到战略制定时,与其他行业相比,医疗器械行业具有特殊的特点。医疗器械行业以先进技术为基础,将患者安全放在首位,需要持续的产品升级。因此,这是员工投资教育和培训的重要行业。分析显示了根据医疗器械企业的经营战略和组织文化对教育培训投资的有效性。人们证实,当医疗器械公司创造创新文化时,他们的表现有所改善。这也表明,当医疗器械企业采取成本领先战略时,他们需要增加对教育和培训的投资,以提高公司绩效。
    UNASSIGNED: Strategies focus on securing the competitiveness of medical device corporations by strengthening their organizational capabilities, which, in turn, ensure their continuous development. This study aims to investigate both management strategies and organizational culture, which may affect the performance of these companies, and analyzes the influence of education and training investment.
    UNASSIGNED: We used data from the 3rd to 6th Human Capital Corporate Panel surveys by the Korea Research Institute for Vocational Education and Training as well as data from the Korea Information Service and 6,112 workers and 260 companies were analyzed. For the analysis, management strategy and organizational culture were set as independent variables, and corporation performance was set as the dependent variable. Additionally, investment in education and training was set as a control variable between the independent and dependent variables. Corporate performance was analyzed by dividing into organizational satisfaction and organizational commitment.
    UNASSIGNED: Differentiation strategy and innovative culture had a positive (+) effect on organizational satisfaction, while cost leadership strategy and hierarchical culture had a negative (-) effect. On the other hand, in the case of interaction with education and training investment, cost leadership strategy and hierarchical culture had a positive (+) effect, while differentiation strategy and innovation culture had a negative (-) effect. In organizational commitment, innovation culture had a positive (+) effect, and hierarchical culture had a negative (-) effect. In the case of interaction with investment in education and training, only the hierarchical culture had a positive (+) effect.
    UNASSIGNED: The innovation culture positively influenced the performance of medical device companies. Furthermore, cost leadership strategy, hierarchical culture, education and training investment improved the corporate performance of these companies. To enhance corporate performance, these companies should create an innovation culture and invest in education and training in accordance with the organizational culture.
    COVID-19 has proven the excellence of Korea’s medical devices, and the medical device industry is expected to continue to grow due to the increase in chronic disease and non-face-to-face treatment. However, the current medical device industry is monopolized by global companies with capital and technological prowess. To overcome this, Korean medical device companies are developing innovative medical devices centered on start-ups, but now is the time to strategically respond to them in order to compete with global companies. In general, companies establish management strategies for survival and growth by analyzing threats and opportunities based on the market environment to maintain the optimal organization according to market competition, government policies, and changes in consumer needs. Strategies are often established based on the culture of the organizations that make up the company. When it comes to strategy establishment, the medical device industry has special characteristics compared to other industries. The medical device industry is based on advanced technology and puts patient safety first, requiring continuous product upgrades. Therefore, it is an essential industry for employees to invest in education and training. The analysis shows the effectiveness of investment in education and training according to the management strategy and organizational culture of medical device companies. It was confirmed that when medical device companies create an Innovation culture, their performance improves. It also shows that when medical device companies adopt a cost leadership strategy, they need to increase their investment in education and training to improve corporate performance.
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  • 文章类型: Journal Article
    我们建立了有关美国仿制药供应商之间竞争的四个事实,使用IQVIA的全国销售视角™2004Q4-2016Q3数据。我们定义了一个独特的产品市场(“摩尔”),由分子活性成分和给药途径制剂的组合组成,聚集在不同的剂量和强度。我们发现:(i)供应在进入者和退出者中表现出大量搅动;(ii)较旧的通用mel型队列中的体积加权使用浓缩物;(iii)最古老的mel型队列的竞争程度最大,而最年轻的mel型队列的竞争程度最小。只有一个竞争对手的中位数,最年轻的摩尔形式群体的竞争程度非常有限;(iv)供应商-摩尔形式的年收入通常很小,是相对年轻的药物最大的,但严重偏右。这四个事实提供了一个经验平台,在这个平台上构建和实证评估关于仿制药市场结构的假设,性能,以及可能的政策改革。
    We establish four facts concerning competition among U.S. generic drug suppliers, using IQVIA\'s National Sales Perspective™ 2004Q4 - 2016Q3 data. We define a unique product market (\"molform\"), consisting of the combination of a molecule active ingredient and a route of administration formulation, aggregated over different dosages and strengths. We find: (i) supply exhibits substantial churning in entrants and exits; (ii) volume-weighted use concentrates in older generic molform cohorts; (iii) the extent of competition is greatest for the oldest molform cohorts and is smallest for the youngest molform cohorts. With a median of one competitor, the extent of competition in the youngest molform cohort is very limited; and (iv) supplier-molform annual revenues are typically small, are largest for relatively young drugs, but are heavily right skewed. These four facts provide an empirical platform on which to construct and empirically evaluate hypotheses regarding generic drug market structure, performance, and possible policy reforms.
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  • 文章类型: Journal Article
    This paper examines the role of both cost-sharing schemes in health insurance systems and the regulation of entry into the pharmaceutical sector for pharmaceutical R&D expenditure and drug prices. The analysis suggests that both an increase in the coinsurance rate and stricter price regulations adversely affect R&D spending in the pharmaceutical sector. In contrast, entry deregulation may lead to higher R&D spending of pharmaceutical companies. The relationship between R&D spending per firm and the number of firms may be hump-shaped. In this case, the number of rivals which maximizes R&D expenditure per firm is decreasing in the coinsurance rate and increasing in labor productivity.
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