Kurdistan

库尔德斯坦
  • 文章类型: Journal Article
    护士,包括最大的医疗保健行业,在医院心理健康障碍的识别和管理中发挥重要作用。
    该研究评估了非精神科护士的知识和态度,以及他们在整个职业生涯中与抑郁症患者的遭遇。
    这是一项横断面描述性研究,在2022年10月至11月期间,对来自伊拉克库尔德斯坦地区不同医院的400名非精神病护士进行了研究。独立的学生t检验,单向方差分析,和二元逻辑回归用于评估与抑郁知识和态度相关的可能因素。
    在这项研究中,对400名非精神科护士进行了检查,显示平均年龄为31.57±8.59岁。他们对抑郁的知识和态度的平均得分最高为11分(标准偏差1.15)中的5.41分和18分(标准偏差1.83)中的5.15分,分别。值得注意的是,观察到参与者婚姻状况的平均知识得分差异(P=.044),而平均态度得分的差异与参与者的性别有关(P=.010)。经过二元逻辑回归分析,没有一个独立变量与良好的知识相关。然而,性别是影响抑郁态度的重要因素(比值比:0.51;95%置信区间:0.30-0.86;P=.012).随后,在多元二元逻辑回归分析中,性别持续显著性(校正比值比:0.573;95%置信区间:0.348-0.942;P=0.028)是影响非精神科护士对抑郁态度的关键变量.
    根据这项研究的结果,护士对抑郁症的认识和管理能力不足。据经验和报道,护士缺乏对抑郁症管理的知识和态度。这项研究强调了护士在管理抑郁症方面的技能存在显著差距。敦促立即改进培训计划。定制这些计划以提高护士识别和管理抑郁症的能力至关重要。
    UNASSIGNED: Nurses, comprising the largest profession in healthcare, play a significant role in the identification and management of mental health disorders in hospitals.
    UNASSIGNED: The study assessed the knowledge and attitudes of non-psychiatric nurses and their encounters with depressive patients throughout their careers.
    UNASSIGNED: This was a cross-sectional descriptive study with 400 non-psychiatric nurses from different hospitals in the Kurdistan Region of Iraq during October and November 2022. The independent Student\'s t-test, one-way analysis of variance, and binary logistic regression were used to assess possible factors associated with knowledge and attitude toward depression.
    UNASSIGNED: In this study, 400 non-psychiatric nurses were examined, revealing a mean age of 31.57 ± 8.59 years. Their mean scores for knowledge and attitude toward depression were 5.41 out of a maximum of 11 (standard deviation 1.15) and 5.15 out of 18 (standard deviation 1.83), respectively. Notably, differences in mean knowledge scores were observed concerning participant marital status (P = .044), while disparities in mean attitude scores are related to participant gender (P = .010). Upon binary logistic regression analysis, none of the independent variables exhibited an association with good knowledge. Nevertheless, gender emerged as a significant factor influencing attitude toward depression (odds ratio: 0.51; 95% confidence interval: 0.30-0.86; P = .012). Subsequently, in the multivariate binary logistic regression analysis, gender sustained significance (adjusted odds ratio: 0.573; 95% confidence interval: 0.348-0.942; P = .028) as the key variable impacting attitudes toward depression among non-psychiatric nurses.
    UNASSIGNED: Based on the results of this study, nurses have insufficient awareness and management skills for depression. It has been experienced and reported that nurses lack knowledge and an attitude toward depression management. The study highlights a significant gap in nurses\' skills for managing depression, urging the immediate improvement of training programs. Customizing these programs to enhance nurses\' abilities in identifying and managing depression is crucial.
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  • 文章类型: Journal Article
    背景:治疗依从性是控制糖尿病疾病的主要关键。该研究旨在确定2型糖尿病(T2DM)患者治疗依从性的患病率。研究依从性对血糖水平升高的潜在影响,并确定在不遵守处方药中起作用的关键因素。
    方法:采用横断面研究方法,从2022年2月至2022年4月在伊拉克库尔德斯坦地区苏莱曼尼亚市的糖尿病和内分泌中心和沙尔医院收集所有T2DM患者的数据。数据收集是通过结构化问卷进行的。使用Morisky服药依从性量表(4项)评估药物依从性的患病率,糖化血红蛋白测试(A1C)用于确定血糖水平。
    结果:共研究了300名参与者,超过一半的人(192;64%)表示他们没有坚持使用抗糖尿病药物。非依从性与较高的A1C显著相关。不遵守的几个障碍被确定为多种药物,感觉给的剂量很高,缺乏资金,和副作用209(70%),116(39%),113(38%),103(34%),分别。
    结论:本研究结果显示,大多数T2DM患者不坚持用药。这种不坚持与较高的A1C水平显着相关,强调药物依从性在有效管理糖尿病中的关键作用。该研究还揭示了多种障碍,例如服用多种处方,认为剂量过大,缺乏资金,并经历副作用,这有助于糖尿病患者的不依从性。这些发现强调了医疗保健提供者需要解决这些障碍,并制定量身定制的策略来提高糖尿病患者的药物依从性。
    BACKGROUND: Treatment adherence is a primary key in controlling diabetes disease. The study aims to determine the prevalence of treatment adherence in type 2 diabetes mellitus (T2DM) patients, investigate the potential influence of adherence on elevated blood glucose levels, and identify the key factors which play a role in non-adherence to the prescribed drugs.
    METHODS: A cross-sectional study method was utilized to collect data from all T2DM patients at the Diabetic and Endocrine Centre and Shar Hospital in Sulaymaniyah city in the Kurdistan region of Iraq from February 2022 to April 2022. The data collection was performed through a structured questionnaire. The prevalence of drug adherence was assessed using the Morisky Medication-Taking Adherence Scale (4-item), and the glycated hemoglobin test (A1C) was used to determine the blood glucose level.
    RESULTS: A total of 300 participants were studied, and more than half of them (192; 64%) revealed that they did not adhere to their anti-diabetic medications. Non-adherence was significantly associated with higher A1C. Several barriers to non-adherence were identified as multiple medications, feeling the dose given is high, lack of finance, and side effects by 209 (70%), 116 (39%), 113 (38%), and 103 (34%), respectively.
    CONCLUSIONS: The current study\'s result revealed that most T2DM patients have no adherence to their medication. This non-adherence is significantly linked to higher A1C levels, emphasizing the critical role of medication compliance in managing diabetes effectively. The study also sheds light on the multiple barriers such as taking multiple prescriptions, the perception that the dose is excessive, lack of finances, and experiencing side effects, which contribute to non-adherence among diabetes patients. These findings underscore the need for healthcare providers to address these barriers and develop tailored strategies to enhance medication adherence among individuals with diabetes.
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  • 文章类型: Journal Article
    地中海贫血是伊拉克的健康问题之一,尤其是在库尔德斯坦.2008年在库尔德斯坦建立了婚前强制性预防性筛查计划,这使我们能够研究该地区新婚年轻人中不同血红蛋白病的患病率。共有1154名受试者(577对夫妇)参加科亚区,婚前保健中心,使用红细胞指数进行筛选。那些平均红细胞体积(MCV)<80fl且平均红细胞血红蛋白(MCH)<27pg的人进行了高效液相色谱和铁研究。在接受评估的1154人中,183(11.9%)的MCV和MCH较低。在前183个科目中,69(5.97%)具有β地中海贫血性状,10人(0.86%)具有δβ地中海贫血性状,在我们的研究中没有记录到其他血红蛋白病。在所有577对夫妇中,有4.7%的人有二级血缘关系。在两对夫妇中,两个伴侣都有β-地中海贫血特征,并且都是近亲。两对夫妇在咨询后决定分开。根据目前的研究,婚前筛查计划在减少库尔德人人群中新增地中海贫血主要病例数量方面的作用值得称赞.因此,建议在伊拉克各地进行强制性婚前筛查。
    Thalassemia major is one of the health problems in Iraq, especially in Kurdistan. Pre-marriage mandatory preventive screening program was established in Kurdistan in 2008, which allowed us to study the prevalence of different hemoglobinopathies among newly married young adults in this region. A total of 1154 subjects (577 couples) attending the Koya district, premarital Health center, were screened using red cell indices. Those who had mean corpuscular volume (MCV)<80 fl and mean corpuscular hemoglobin (MCH)<27 pg had high-performance liquid chromatography and iron studies. Out of 1154 individuals that were evaluated, 183 (11.9%) had low MCV and MCH. Of the former 183 subjects, 69 (5.97%) had β-thalassemia trait, 10 (0.86%) had δβ-thalassemia trait, and no other hemoglobinopathies were recorded in our study. There was second-degree consanguinity in 4.7% of all 577 couples. In two couples, both partners had β-thalassemia trait and both were consanguineous. Both couples decided to separate after counseling. Based on the current study, the role of the premarital screening program in decreasing the number of new thalassemia major cases among the Kurdish population is laudable. Therefore, mandatory premarital screening is advised in all parts of Iraq.
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  • 文章类型: Journal Article
    目标:近年来,伊拉克的自杀率有所增加,使其成为一个重大的公共卫生问题。本系统评价研究了伊拉克和库尔德斯坦地区自杀行为的患病率。
    方法:本研究遵循PRISMA指南,在PubMed上进行搜索,MEDLINE,WebofScience,谷歌学者。在最初确定的153种出版物中,只有18篇完整文章符合纳入标准,由于资格标准等原因,排除了135篇文章,重复,掠夺性出版物和缺乏相关性和缺乏质量数据。
    结果:在2015年至2016年期间,伊拉克(不包括库尔德斯坦)的自杀率从1.09升至1.31/100,000,而库尔德斯坦的自杀率估计为3.83/100,000。关于参考组规模和人口数字的有限数据使得具体的费率计算具有挑战性。自杀在女性中更为普遍,那些15-40岁的人,以及有精神障碍的人。促成因素包括家庭暴力,心理健康问题,传统规范。城市居民的自杀率普遍高于农村居民。常见的自杀行为包括自焚,悬挂,火器,从高处跳跃,用杀虫剂自我中毒.
    结论:伊拉克的自杀率,正如本系统审查所表明的,需要紧急关注和有效的公共卫生举措。社会的相互作用,经济,文化,心理因素强调需要全面的预防方案。此外,一个至关重要的要求是实施一种收集自杀数据的标准化方法,以提高对流行病学的了解。
    OBJECTIVE: The suicide rate has increased in Iraq in recent years, making it a major public health concern. This systematic review examines the prevalence of suicidal behaviours in the Iraq and Kurdistan region.
    METHODS: This study adhered to the PRISMA guidelines, conducting searches on PubMed, MEDLINE, Web of Science, and Google Scholar. Out of 153 initially identified publications, only 18 full articles met the inclusion criteria, with 135 articles excluded due to reasons such as eligibility criteria, duplication, predatory publications and lack of relevance and lack of quality data.
    RESULTS: The suicide crude rate in Iraq (excluding Kurdistan) rose from 1.09 to 1.31 per 100,000 between 2015 and 2016, while Kurdistan had an estimated rate of 3.83 per 100,000 during the same period. Limited data on reference group sizes and population figures make specific rate calculations challenging. Suicide is more prevalent among women, those aged 15-40, and individuals with mental disorders. Contributing factors include domestic violence, mental health issues, and traditional norms. Urban residents generally have higher suicide rates than rural residents. Common suicide behaviours include self-immolation, hanging, firearms, jumping from heights, and self-poisoning with pesticides.
    CONCLUSIONS: The prevalence of suicide in Iraq, as indicated by this systematic review, requires urgent attention and effective public health initiatives. The interplay of social, economic, cultural, and psychological factors emphasizes the need for comprehensive prevention programs. Additionally, a crucial requirement is the implementation of a standardised method for collecting suicide data to improve epidemiological understanding.
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  • 文章类型: Journal Article
    一个新物种,Veronicakurdistanica(车前草科),进行了描述和说明。它生长在伊朗西部高山地区(库尔德斯坦省)的石灰岩悬崖上。该新物种属于V.kurdica物种组,被认为与V.daranica密切相关,V.Khorassanica和V.Kurdica,与新物种进行比较。nrDNA(ITS)区域的分子系统发育分析证实了这种关系。Veronicakurdistanica与上述物种的区别在于其腺毛,叶子和苞片的长度和形状,每个总状花序的花数,花萼和花冠的长度和宽度,胶囊和种子的大小。
    A new species, Veronicakurdistanica (Plantaginaceae), is described and illustrated. It grows on limestone cliffs in mountainous alpine areas of western Iran (Kurdistan province). The new species belongs to the species group of V.kurdica and is considered to be closely related to V.daranica, V.khorassanica and V.kurdica, with which the new species is compared. Molecular phylogenetic analysis of nrDNA (ITS) region confirms this relationship. Veronicakurdistanica is distinguished from the mentioned species by its glandular indumentum, length and shape of leaves and bracts, number of flowers per raceme, length and width of calyx and corolla, and size of capsules and seeds.
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  • 文章类型: Journal Article
    背景:关于自闭症的许多方面与社会结构密切相关,政策,和动力动态,默默地影响自闭症谱系内个体的福祉。这项研究的目的是探索这些被忽视的方面使用一个理论框架称为“结构性暴力。\"
    方法:这项研究是在库尔德斯坦进行的,伊朗,并选择了定性纵向方法。采用目的抽样方法选择参与者,有11位家长参加。研究数据包括29次访谈,使用主题指南进行了2年。利用主题分析和基于矩阵的方法进行数据分析。为了加强这项研究的科学严谨性,四个标准,包括古巴和林肯的原则,实施以确保方法的准确性。
    结果:研究结果强调了结构性暴力影响自闭症儿童及其家庭的四种主要形式:获得医疗保健,地理差异,意识和耻辱,贫困和财政负担。此外,该研究确定了11个与自闭症和家庭背景下的结构性暴力相关的子主题。
    结论:我们说明了结构性力量如何为获得适当的医疗保健服务造成障碍,加剧基于种族和地理的歧视,永久的污名,并导致贫困和无法满足基本需求。这些因素不仅加剧了健康问题,而且加深了自闭症儿童和家庭在医疗保健获取和结果方面的现有差距。我们强调迫切需要进行系统性变革以解决这些问题。提高公众意识至关重要,提供更好的健康和支持服务,并解决导致这些不平等的经济和政治因素。
    BACKGROUND: There are many dimensions regarding autism that are closely connected to social structures, policies, and power dynamics, silently impacting the well-being of individuals within the autism spectrum. This research aims to explore these overlooked aspects using a theoretical framework called \"structural violence.\"
    METHODS: The study was conducted in Kurdistan, Iran, and a qualitative longitudinal approach was chosen. A purposive sampling method was employed to select the participants, with 11 parents taking part. The study data comprised 29 interviews using a topic guide conducted over a span of 2 years. Thematic analysis and a matrix-based approach were utilized for data analysis. To enhance the scientific rigor of this research, four criteria, including Guba and Lincoln\'s principles, were implemented to ensure methodological accuracy.
    RESULTS: The research findings highlight four primary forms through which structural violence impacts children on the autism spectrum and their families: access to healthcare, geographic disparities, awareness and stigma, and poverty and financial burden. Additionally, the study identified 11 subthemes related to structural violence in the context of autism and families.
    CONCLUSIONS: We illustrated how structural forces create barriers to accessing adequate healthcare services, exacerbate discrimination based on ethnicity and geography, perpetuate stigma, and contribute to poverty and the inability to meet basic needs. These factors not only worsen health issues but also deepen existing disparities in healthcare access and outcomes for children on the autism spectrum and families. We emphasize the urgent need for systemic changes to address these issues. It is essential to promote public awareness, provide better access to health and support services, and address economic and political factors that contribute to these inequalities.
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  • 文章类型: Journal Article
    背景:妇女出于各种原因求助于Kolberi,这给他们带来了许多挑战。因此,必须找出这些原因和问题。由于从未进行过与该参与者打交道的研究,本研究旨在确定伊朗库尔德妇女中Kolberi的原因和后果。
    方法:本研究使用扎根理论方法调查了28名女性库尔德Kolbers。为了实现多个参与者,目的性,滚雪球,采用理论抽样方法,而面对面的半结构化访谈被用来收集数据。数据收集和分析的过程耗时10个月,2022年4月至12月。使用Strauss和Corbin方法和MAXQDA-20018软件分析数据。还满足了Guba和Lincoln标准,以提高结果的可信度。
    结果:对数据的分析导致了143个初始代码,31个子类别,和9个主要类别:因果条件(个体特征和经济因素);诱发条件(社会和文化因素,家庭因素);干预条件(Kolberi的优势和特征);策略(加强与Kolberi的兼容性);和后果(个人问题,社会问题和积极后果)。
    结论:对妇女进行职业技能培训,提供就业条件等措施,越来越多的社会,金融,对没有监护人的女性的精神支持,创造边境市场,扩大女性手工艺品可以帮助防止女性Kolberi。
    Women turn to Kolberi for various reasons, which cause numerous challenges for them. Thus, it is imperative to identify these causes and problems. Since no study has ever been undertaken to deal with this participant, the present research aims to identify the causes and consequences of Kolberi among Kurdish women in Iran.
    The present research uses the grounded theory approach to investigate 28 female Kurdish Kolbers. To achieve several participants, purposive, snowball, and theoretical sampling methods were used, while face-to-face semi-structured interviews were used to gather data. The process of data collection and analysis took 10 months, from April to December 2022. The data were analyzed using the Strauss and Corbin method and MAXQDA-20018 software. The Guba and Lincoln criteria were also met to increase the trustworthiness of the results.
    Analysis of the data led to 143 initial codes, 31 subcategories, and 9 main categories: Causal condition (individual characteristics and economic factors); predisposing conditions (social and cultural factors, familial factors); intervening conditions (advantages and characteristics of Kolberi); strategies (strengthening compatibility with Kolberi); and consequences (individual problems, social problems and positive consequences).
    Measures such as training occupational skills for women and providing employment conditions for them, increasing social, financial, and mental support for women without guardians, creating border markets, and expanding women\'s handicrafts can help prevent female Kolberi.
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  • 文章类型: Journal Article
    照顾不同发育轨迹的儿童带来各种挑战,这在低资源环境中往往会加剧。国际研究表明,抚养自闭症儿童会严重影响家庭照顾者,尤其是母亲。伊拉克库尔德斯坦地区(KRI)自闭症患者以及父亲和母亲的护理信息匮乏。这项研究使用经过验证的评定量表来衡量KRI中自闭症儿童的父母在照料方面的异同,以衡量其总体幸福感的各个方面。两年多了,118名自闭症患者的父母(81名母亲和37名父亲)自我完成了评定量表,通过与主要为他们所知的服务人员的个别访谈进一步讨论了这些问题。调查结果表明,母亲和父亲也受到了类似的影响。尽管他们的一般健康状况评分没有统计学上的显着差异,压力的来源,家庭功能,以及对护理的满意度,大多数父母对所有措施的评价都很高。此外,在异常行为检查表中对孩子评分较高的父母对其一般健康问题的评分明显较高,对其照顾角色的满意度较低.与患有自闭症的男性个体和在三岁之前接受诊断的儿童的父母相比,患有自闭症的女性个体的父母也承受更大的压力。与孩子年龄较大时接受诊断的父母相比,他们孩子的行为问题较少。在这个样本中,母亲和父亲似乎同样受到照顾自闭症儿童的影响,这与其他国家的调查结果相反。然而,在这个地区,夫妇与更广泛的家庭之间的家庭纽带可能产生了影响,在低资源环境中进行进一步的跨文化研究可以帮助阐明,尽管这带来了挑战。这些发现对KRI的卫生当局改善对照顾自闭症儿童的母亲和父亲提供的支持具有政策意义。这是目前很少提供给他们。
    Caring for children with different developmental trajectories brings various challenges, which are often exacerbated in low-resource settings. International research has shown that raising a child with autism strongly impacts family caregivers, particularly mothers. There is a dearth of information regarding caregiving for individuals with autism in the Kurdistan Region of Iraq (KRI) and for fathers as well as mothers. This study examined the similarities and differences in caregiving for mothers and fathers of a child with autism in KRI using validated rating scales to measure various aspects of their general well-being. Over two years, a sample of 118 parents of individuals with autism (81 mothers and 37 fathers) self-completed the rating scales, which were further discussed through individual interviews with service personnel mainly known to them. The findings indicated that mothers and fathers were similarly impacted. Although there were no statistically significant differences in the ratings of their general health, sources of stress, family functioning, and satisfaction with caregiving, the majority of parents had elevated ratings on all the measures. In addition, parents who rated their children higher on the Aberrant Behavior Checklist had significantly higher scores on their general health issues and were less satisfied with their caregiving role. Parents of female individuals with autism were also significantly more stressed compared to the male individuals with autism and parents of children who received a diagnosis before three years of age, reported fewer behavioral problems with their child compared to the parents who received a diagnosis when the child was older. In this sample, mothers and fathers seem to be similarly impacted by caring for a child with autism, which is contrary to findings from other countries. However, in this region, family bonds between couples and the wider family may have had an influence which further cross-cultural research in low-resource settings could help elucidate, notwithstanding the challenges this poses. The findings have policy implications for health authorities in the KRI to improve the support provided to both mothers and fathers who care for children with autism, which presently is rarely available to them.
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  • 文章类型: Journal Article
    背景:宫颈上皮内瘤变(CIN)是指宫颈鳞状细胞的异常变化,在II级和III级中发生更明显的变化,称为高度鳞状上皮内病变(HSIL)。
    目的:这项研究旨在评估居住在库尔德斯坦地区的女性宫颈上皮内瘤变的患病率,并探讨HSIL的潜在危险因素。伊拉克。
    方法:该研究包括1300名女性参与者的样本,他们在库尔德斯坦地区的几家医院进行了Papanicolaou(pap)涂片检查。该研究的目的是确定这些妇女中宫颈感染的患病率。这是一项从2021年1月至2021年12月底进行的多中心研究,旨在确定子宫颈抹片检查以及CIN与宫颈癌之间的关系。1300名参与者中只有120名(9.23%)患有宫颈或阴道问题。巴氏涂片,也被称为pap测试,是一种常规筛查程序,用于检测可能表明宫颈癌或癌前病变的异常宫颈细胞。该程序涉及从子宫颈收集细胞样品。
    结果:这项研究中最重要的细节是接受过子宫颈抹片检查的女性的年龄组和百分比。有四名女性宫颈癌检测呈阳性,占120例宫颈或阴道问题参与者的3.33%。然而,有116名(96.67%)女性检测呈阴性。关于宫颈或阴道问题参与者的炎症发生率分布,有114名(95%)女性患有炎症,而有6名(5%)女性无炎症。在每个年龄组,有和没有宫颈癌的女性人数,以及相应的百分比,被考虑。数据表明,宫颈癌的发病率随着年龄的增长而增加,因为在老年组中观察到更高的百分比。该研究强调了定期筛查和针对特定年龄的宫颈癌预防和检测策略的重要性,以确保早期诊断和有效的医疗干预。
    结论:宫颈癌的患病率相对较低,只有0.31%的参与者被诊断为宫颈癌。大多数,占99.69%,没有宫颈癌。这些结果强调了子宫颈抹片检查筛查作为早期发现和预防宫颈癌的宝贵工具的重要性。他们还强调了定期放映的重要性,尤其是年轻女性,早期检测和治疗宫颈异常。
    BACKGROUND:  Cervix intraepithelial neoplasia (CIN) refers to abnormal changes in the squamous cells of the cervix, with more significant changes known as high-grade squamous intraepithelial lesions (HSIL) occurring in grades II and III.
    OBJECTIVE:  The study aimed to estimate the prevalence of cervical intraepithelial neoplasia and explore potential risk factors for HSIL among women living in the Kurdistan region, Iraq.
    METHODS:  The research encompassed a sample size of 1300 female participants whose Papanicolaou (pap) smears were taken in several hospitals located within the Kurdistan region. The objective of the study was to determine the prevalence of cervical infection among these women. This was a multi-centre study conducted from January 2021 to the end of December 2021 for the determination of pap smears and the relationship between CIN and cervical cancer. Only 120 (9.23%) of those 1300 participants suffered from cervical or vaginal problems. A pap smear, also known as a pap test, is a routine screening procedure used to detect abnormal cervical cells that may indicate cervical cancer or precancerous conditions. The procedure involves collecting a sample of cells from the cervix.
    RESULTS:  The most important details in this study are the age groups and percentages of women who have undergone a pap smear. There were four women who tested positive for cervical cancer, accounting for 3.33% of the 120 participants with cervical or vaginal problems. However, there were 116 (96.67%) women who tested negative. With regard to the distribution of inflammation rates among the participants with cervical or vaginal problems, there were 114 (95%) women who suffered inflammation, whereas there were six (5%) women without inflammation. In each age group, the numbers of women with and without cervical cancer, as well as the corresponding percentages, were considered. The data suggest that the incidence of cervical cancer tends to increase with age since higher percentages were observed in older age groups. The study highlights the importance of regular screenings and age-specific cervical cancer prevention and detection strategies to ensure early diagnosis and effective medical interventions.
    CONCLUSIONS:  The prevalence of cervical cancer cases was relatively low, with only 0.31% of the total participants diagnosed with cervical cancer. The majority, accounting for 99.69%, did not have cervical cancer. These results highlight the importance of pap smear screenings as a valuable tool for early detection and prevention of cervical cancer. They also highlight the importance of regular screenings, especially for younger women, to detect and treat cervical abnormalities at an early stage.
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  • 文章类型: Journal Article
    β-地中海贫血是伊拉克库尔德斯坦地区普遍存在的遗传性红细胞疾病。为了确定后者区域中常见的β-地中海贫血突变的染色体背景,我们研究了202条β-地中海贫血染色体中的β-珠蛋白基因簇单倍型。单倍型分析利用限制性片段长度多态性-通过β-珠蛋白基因簇对七个限制性位点进行PCR。观察到IVS-II-1(G>A)主要与单倍型III(68.8%)相关,IVS-1-110(G>A),密码子8/9(+G)和密码子44(-C)与单倍型I(90.0%,100%,和62.5%),IVS-1-6(T>C)单倍型VI(97.4%),密码子8(-AA)与单倍型IV(75%),密码子5(-CT)和IVS1.1(G>A)具有单倍型V(分别为55.6%和58.3%),密码子39(C>T)和IVS1.5(G>C)主要与单倍型VII相关(分别为85.7%和75%)。这些观察结果支持这样的观点,即虽然一些突变可能起源于库尔德斯坦地区,其他人更有可能是由邻国或印度次大陆的基因流动带来的。一些β-地中海贫血缺陷与多于一种单倍型的关联可能是由于突变或重组事件。
    β-thalassemia is a prevalent inherited red cell disorder in the Kurdistan region of Iraq. To determine the chromosomal background of the frequent β-thalassemia mutations in the latter region, we investigated the β-globin gene cluster haplotypes in 202 β-thalassemia chromosomes. Haplotypes analysis utilized restriction fragment length polymorphism-PCR of seven restriction sites through the β-globin gene cluster. It was observed that IVS-II-1 (G > A) was mainly associated with haplotype III (68.8%), IVS-1-110 (G > A), codon 8/9 (+G) and codon 44 (-C) with haplotype I (in 90.0%, 100%, and 62.5% respectively), IVS-1-6 (T > C) with haplotype VI (97.4%), codon 8 (-AA) with haplotype IV (75%), codon 5(-CT) and IVS1.1 (G > A) with haplotype V (55.6% and 58.3% respectively), while codon 39 (C > T) and IVS1.5 (G > C) were mainly associated with haplotype VII (85.7% and 75% respectively). These observations support the notion that while some mutations may have originated in the Kurdistan region, others were more likely brought in by gene flow from neighboring countries or the Indian subcontinent. The association of some β-thalassemia defects with more than one haplotype may be due to mutations or recombination events.
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