背景：中风后疾病综合征（POIS）是一种极为罕见的泌尿生殖系统疾病，对功能和性活动产生重大负面影响。
目的：一名34岁男性出现POIS症状，并确认POIS的过敏成分。建议自体精液强化免疫治疗。
方法：治疗持续14个月，共20次就诊。两个前臂的改良和强化皮下免疫治疗显著缩短了治疗时间并改善了预后。耐受性高，无不良反应或过度活跃反应。
方法：通过使用自体精液强化免疫疗法改善POIS症状。
结果：改善显著，足以允许更高的性活动，逐步恢复私人和专业活动。
结论：自体精液强化免疫治疗似乎是治疗疑似免疫变应原性POIS患者的一种有效和安全的选择。据我们所知,这是POIS首个如此密集且有效的过敏原特异性免疫治疗.Wrotynska-BarczynskaJ,斯瓦特.特警E,伯杰A,etal.强化脱敏是一种有效的治疗后疾病综合症（POIS）。SexMed2022；10:100474。
BACKGROUND: Postorgasmic illness syndrome (POIS) is an extremely rare urogenital disease which significantly and negatively impacts the functioning and sexual activity.
OBJECTIVE: A 34-year-old male presented with POIS symptoms and confirmed the allergic component of the POIS. Intensified immunotherapy with autologous semen was recommended.
METHODS: The treatment lasted 14 months and included 20 visits. Modified and intensified subcutaneous immunotherapy in both forearms significantly shortened the therapy and improved the outcome, with high-tolerance and no adverse effects or hyperactive responses.
METHODS: Improvement in POIS symptoms through the use of intensified immunotherapy with autologous semen.
RESULTS: The improvement was significant enough to allow for higher sexual activity, and gradual resumption of private and professional activity.
CONCLUSIONS: Intensified immunotherapy with autologous semen seems an effective and safe option for treating patients with suspected immune-allergenic POIS. To the best of our knowledge, this has been the first such intensive and effective allergen-specific immunotherapy of POIS. Wrotynska-Barczynska J, Swat. Swat E, Berger A, et al. Intensified Hyposensitization Is an Effective Treatment of Postorgasmic Illness Syndrome (POIS). Sex Med 2022;10:100474.
