背景:受体区毛囊周围红斑(RPE)可能会延迟毛发移植后移植物的生长。然而,目前缺乏RPE的观察性临床研究。
目的:研究RPE的临床特征和危险因素,同时分析其与移植物生长的相关性。
方法:我们在2020年6月至2023年1月之间进行了一项多中心回顾性队列研究。
结果:共纳入1090名参与者,178(16.33%)显示轻度RPE,56(5.14%)显示中度RPE,10例(0.92%)出现严重RPE。RPE患者有严重的毛干脱落(P<0.001)和较低的移植物存活率(P<0.001)。Logistic回归分析显示毛囊炎是轻度RPE(OR6.061,95%CI3.343~10.991,P<0.001)和中度RPE(OR3.397,95%CI1.299~8.882,P=0.013)的显著危险因素。此外,术后第一次洗头与中度RPE(OR0.724,95%CI0.553-0.947,P=0.018)和重度RPE(OR1.553,95%CI1.156-2.086,P=0.003)的发生有关。
结论:RPE是一种术后并发症,与高毛干脱落率和低移植物成活率密切相关。术后毛囊炎和不及时的术后首次洗毛都可能诱发RPE的发生。
方法:本期刊要求作者为每篇文章分配一定程度的证据。对于这些循证医学评级的完整描述,请参阅目录或在线作者说明www。springer.com/00266.
BACKGROUND: Recipient-area perifollicular erythema (RPE) may delay graft growth after hair transplantation. However, there is currently a lack of observational clinical studies of RPE.
OBJECTIVE: To study the clinical features and risk factors associated with RPE while analyzing its correlation with graft growth.
METHODS: We conducted a multicenter retrospective cohort study between June 2020 and January 2023.
RESULTS: A total of 1090 participants were included, 178 (16.33%) showed mild RPE, 56 (5.14%) showed moderate RPE, and 10 (0.92%) showed severe RPE. Patients with RPE had severe hair shaft shedding (P < 0.001) and a lower survival rate (P < 0.001) of grafts. Logistic regression analysis showed that folliculitis is a significant risk factor for mild RPE (OR 6.061, 95% CI 3.343-10.991, P < 0.001) and moderate RPE (OR 3.397, 95% CI 1.299-8.882, P = 0.013). Besides, untimely first postoperative hair washing was associated with the development of moderate RPE (OR 0.724, 95% CI 0.553-0.947, P = 0.018) and severe RPE (OR 1.553, 95% CI 1.156-2.086, P = 0.003).
CONCLUSIONS: RPE is a postoperative complication closely related to high hair shaft shedding proportion and low graft survival rate. Both postoperative folliculitis and untimely first postoperative hair washing may induce the occurrence of RPE.
METHODS: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .