关键词: Excimer laser Frontal fibrosing alopecia Hair transplantation Histopathology Intralesional therapy Pathogenesis Systemic treatments Topical treatments Trichoscopy

来  源:   DOI:10.1007/s13555-024-01186-0   PDF(Pubmed)

Abstract:
Frontal fibrosing alopecia (FFA) represents a distinctive form of primary lymphocytic scarring alopecia characterized by fronto-temporal hair recession and eyebrow hair loss. While predominantly affecting postmenopausal women, FFA also occurs in women of reproductive age and men, with variations observed across different ethnic groups. Genetic predisposition, environmental factors and inflammatory pathways contribute to its pathogenesis, with evolving diagnostic criteria enhancing accuracy. FFA treatment lacks standardization, encompassing topical, systemic and physical therapies, while hair transplantation remains a temporary solution. This article reviews the current understanding of FFA, aiming to provide clinicians with updated insights for its management.
摘要:
额叶纤维性脱发(FFA)代表了原发性淋巴细胞性瘢痕性脱发的一种独特形式,其特征是额颞叶毛发退缩和眉毛脱发。虽然主要影响绝经后妇女,FFA也发生在育龄女性和男性中,不同种族之间观察到的差异。遗传易感性,环境因素和炎症途径有助于其发病机制,随着不断发展的诊断标准,提高了准确性。FFA治疗缺乏标准化,涵盖局部,全身和物理治疗,而头发移植仍然是一个暂时的解决方案。本文回顾了目前对FFA的理解,旨在为临床医生提供有关其管理的最新见解。
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