{Reference Type}: Journal Article
{Title}: Risk Factors and Hazards of Recipient-Area Perifollicular Erythema After Hair Transplantation: A Multicenter Retrospective Cohort Study.
{Author}: Zhang J;Zhao Y;Zhang J;Zhou Y;Yi Y;Lei R;Qu Q;Hu Z;Gao Z;Li Y;Tang Q;Miao Y;
{Journal}: Aesthetic Plast Surg
{Volume}: 48
{Issue}: 15
{Year}: 2024 Aug 7
{Factor}: 2.708
{DOI}: 10.1007/s00266-024-04166-z
{Abstract}: BACKGROUND: Recipient-area perifollicular erythema (RPE) may delay graft growth after hair transplantation. However, there is currently a lack of observational clinical studies of RPE.
OBJECTIVE: To study the clinical features and risk factors associated with RPE while analyzing its correlation with graft growth.
METHODS: We conducted a multicenter retrospective cohort study between June 2020 and January 2023.
RESULTS: A total of 1090 participants were included, 178 (16.33%) showed mild RPE, 56 (5.14%) showed moderate RPE, and 10 (0.92%) showed severe RPE. Patients with RPE had severe hair shaft shedding (P < 0.001) and a lower survival rate (P < 0.001) of grafts. Logistic regression analysis showed that folliculitis is a significant risk factor for mild RPE (OR 6.061, 95% CI 3.343-10.991, P < 0.001) and moderate RPE (OR 3.397, 95% CI 1.299-8.882, P = 0.013). Besides, untimely first postoperative hair washing was associated with the development of moderate RPE (OR 0.724, 95% CI 0.553-0.947, P = 0.018) and severe RPE (OR 1.553, 95% CI 1.156-2.086, P = 0.003).
CONCLUSIONS: RPE is a postoperative complication closely related to high hair shaft shedding proportion and low graft survival rate. Both postoperative folliculitis and untimely first postoperative hair washing may induce the occurrence of RPE.
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