目的:牙龈是牙齿周围的支持组织之一,可受到各种肿瘤或非肿瘤性病变的影响。以前的研究已经检查了几种类型的牙龈病变,但是缺乏标准化的分类系统阻碍了有意义的比较。此外,许多研究主要集中在反应性病变上。我们的研究旨在通过调查不同年龄段的牙龈病变的患病率来促进对牙龈病变的理解。性别,网站,以及他们的临床表现。这项研究可以提高诊断准确性和治疗策略。
方法:这项回顾性研究基于22年的活检来探讨牙龈病变的患病率。病人的人口统计细节,包括年龄,性别,系统收集病变的临床表现。这些病变分为六组。描述性统计,独立性的χ2检验,和单因素方差分析用于数据分析。
结果:在7668个活检病灶中,684(8.9%)病变位于牙龈,女性发生率更高(63.5%)。软组织肿瘤是牙龈病变中最常见的组(72.1%),周围巨细胞肉芽肿(PGCG)是最常见的病变(21.2%),其次是,化脓性肉芽肿(19.3%),周围骨化性纤维瘤(17.8%)和局灶性纤维增生(7.6%);所有这些主要影响女性,平均年龄在生命的第四个十年下降。鳞状细胞癌被认为是最常见的恶性肿瘤。
结论:在这项研究中,PGCG被发现是伊朗人群牙龈中最常见的病变。需要使用一致分类的进一步分析来确认这些结果。
OBJECTIVE: Gingiva is one of the supporting tissues around the teeth that can be affected by various neoplastic or nonneoplastic lesions. Previous studies have examined several types of gingival lesions, but the lack of a standardized classification system has hindered meaningful comparisons. Additionally, many studies focused primarily on reactive lesions. Our study aims to contribute to the understanding of gingival lesions by investigating their prevalence across age groups, genders, sites, and by their clinical presentation. This research could lead to improved diagnostic accuracy and treatment strategies.
METHODS: This retrospective study explores the prevalence of gingival lesions based on biopsies during a 22-year span. The patient\'s demographic details, including age, gender, and lesion\'s clinical presentation were systematically collected. These lesions were categorized into six groups. Descriptive statistics, χ2 test of independence, and one-way ANOVA were used for data analysis.
RESULTS: Among the 7668 biopsied lesions, 684 (8.9%) lesions were located in the gingiva, with a greater occurrence in women (63.5%). Soft tissue tumors represented the most prevalent group in the gingival lesions (72.1%), and peripheral giant cell granuloma (PGCG) was the most frequent lesion (21.2%), followed by, pyogenic granuloma (19.3%), peripheral ossifying fibroma (17.8%) and focal fibrous hyperplasia (7.6%); all of which predominantly affected women, with mean ages falling in the fourth decade of life. Squamous cell carcinoma was recognized as the most common malignancy.
CONCLUSIONS: In this study, PGCG was found to be the most common lesion in the gingiva in Iranian population. Further analysis using a unanimous categorization is required to confirm these results.