PDF(Pubmed)
Abstract：
Herein, we detail a multidisciplinary approach and sequential treatment for two infants with congenital granular cell epulis (CGCE). Ultrasonic examinations at 34 weeks of gestation revealed prominent oral masses in both fetuses. To devise a carefully considered treatment strategy, a comprehensive multidisciplinary consultation including oral and maxillofacial surgeons, pediatricians, obstetricians, and anesthesiologists was convened. Following cesarean sections, the lesions were successfully removed, measuring approximately 30 × 15 mm and 30 × 20 mm in size, respectively. Immunohistochemical analysis showed that vimentin was positive, S-100 protein was negative, and NSE protein and CD68 protein were negative. These findings underscore the importance of prenatal diagnosis of congenital granular cell epulis for the effective management of these rare benign conditions.
摘要：
在这里，我们详细介绍了针对2例先天性颗粒细胞上皮(CGCE)婴儿的多学科方法和序贯治疗.妊娠34周时的超声检查显示，两个胎儿都有明显的口腔肿块。为了设计一个仔细考虑的治疗策略，全面的多学科咨询，包括口腔颌面外科医生，儿科医生,产科医生,麻醉医师被召集起来.剖腹产后,病灶被成功切除,尺寸约为30×15毫米和30×20毫米，分别。免疫组织化学分析显示波形蛋白阳性,S-100蛋白呈阴性,NSE蛋白和CD68蛋白均为阴性。这些发现强调了先天性颗粒细胞上皮的产前诊断对于有效治疗这些罕见的良性疾病的重要性。
