背景:减肥手术后总体生活质量(QoL)通常得到改善。据报道,在Roux-en-Y胃旁路术(RYGB)后,超过30%的患者出现了包括腹痛在内的胃肠道(GI)症状,并可能对QoL产生负面影响,尤其是GI-QoL.
目的:评估RYGB后短期和长期GI症状和GI-QoL的演变。
方法:两家公立医院方法:邀请减肥手术候选人(n=128,BMI=44.2±7.4)或之前经历了RYGB2-4年(n=161,BMI=29.3±15.9)和5-10年(n=121,BMI=31.3±6.5)的患者填写一份问卷,并结合3份经过验证的问卷(GIQLI,GSRS,和PCS)专门设计用于评估GI-QoL。术前得分比较,早期,和术后后期。
结果:术后早期和晚期GIQLI评分分别从术前的88.1提高到118.6(P<.0001)和109.7(P<.0001)。GSRS得分从15.6提高到10.1(P=0.0001)和12.8(P=0.012),PCS评分从19提高到4.5(P=0.0001)和8.3(P=0.0001),分别。早期GIQLI的GI分从57.4提高到62.1(P=.007),但后期没有显着差异(59.3对57.4,P=.3)。胃肠道症状的心理影响在术后两个时间点都有所降低。
结论:RYGB后GI-QoL明显改善,这种改善持续了10年。胃肠道症状在手术后早期减轻,并且在长期内不会恶化。他们的心理影响明显减少。
BACKGROUND: Overall quality of life (QoL) is generally improved after bariatric surgery. Gastrointestinal (GI) symptoms including abdominal pain have been reported in up to >30% of patients after Roux-en-Y gastric bypass (RYGB), and may negatively influence QoL, especially GI-QoL.
OBJECTIVE: To evaluate the evolution of GI symptoms and GI-QoL short- and long-term after RYGB.
METHODS: Two public hospitals METHODS: Candidates for bariatric surgery (n = 128, BMI = 44.2 ± 7.4) or patients who had undergone RYGB 2-4 years (n = 161, BMI = 29.3 ± 15.9) and 5-10 years (n = 121, BMI = 31.3 ± 6.5) before were invited to complete a questionnaire combining 3 validated questionnaires (GIQLI,
GSRS, and PCS) specifically designed to evaluate GI-QoL. Scores were compared between the preoperative, early, and late postoperative periods.
RESULTS: The GIQLI score improved from 88.1 before surgery to 118.6 (P < .0001) and 109.7 (P < .0001) in the early and late postoperative periods respectively.
GSRS score improved from 15.6 to 10.1 (P = .0001) and 12.8 (P = .012), and PCS-score improved from 19 to 4.5 (P = .0001) and 8.3 (P = .0001), respectively. The GI subscore of the GIQLI improved from 57.4 to 62.1 (P = .007) in the early period but was not significantly different in the late period (59.3 versus 57.4, P = .3). The psychological impact of GI symptoms decreased at both postoperative time points.
CONCLUSIONS: GI-QoL is markedly improved after RYGB, and this improvement persists up to 10 years. GI symptoms decrease early after surgery and do not worsen in the longer term. Their psychological impact is markedly reduced.