目的:分析10年来荧光素眼底血管造影(FFA)在眼底疾病中的应用趋势。
方法:这是一项回顾性研究。2012年1月至2021年12月在温州医科大学眼科医院接受FFA检查的患者包括在内,不包括婴儿。数据包括FFA的眼底疾病和检查时间。
结果:在过去的十年中,我们医院共有37,038例进行了FFA检查,2012年至2021年,每年的数量分别为3,628、2,232、2,230、2,351、3,546、3,924、5,325、4,202、4,432和5,168。排名前三的疾病是中心性浆液性脉络膜视网膜病变(CSC),2012年至2021年的糖尿病视网膜病变(DR)和视网膜静脉阻塞(RVO)。第四到第八的疾病是葡萄膜炎,年龄相关性黄斑变性(AMD),脉络膜新生血管(CNV),从2012年到2020年,视神经病变(ON)和息肉样脉络膜血管病变(PCV)共9年;而视网膜动脉阻塞(RAO)排名第八,而PCV在2021年排名前八.肿瘤,Eale\'s疾病,黄斑出血(MH),多年来,视网膜前膜(ERM)和Coat病的比例一致。从2012年到2021年,疾病成分的比例存在显着统计学差异(p=0.000)。
结论:尽管年度分布发生变化,CSC,DR,和RVO一直被列为需要FFA检查的前三名疾病。变化可能与非侵入性眼底检查仪器和技术的发展有关。表明FFA在诊断和理解眼底疾病方面仍然具有不可替代的性质。
OBJECTIVE: To analyze the trends in the application of fundus fluorescein angiography (FFA) in fundus diseases over ten years.
METHODS: It was a retrospective study. Patients who underwent FFA examinations between Jan 2012 and Dec 2021 in Eye Hospital of Wenzhou Medical University were included, excluding infants. Data included the fundus disease and examination time of FFA.
RESULTS: A total of 37,038 cases underwent FFA examinations in our hospital in the past decade, and the number of each year was 3,628, 2,232, 2,230, 2,351, 3,546, 3,924, 5,325, 4,202, 4,432 and 5,168 from 2012 to 2021, respectively. The top three diseases were central serous chorioretinopathy (CSC), diabetic retinopathy (DR) and retinal vein occlusion (RVO) over the years from 2012 to 2021. The fourth to eighth ranked diseases were uveitis, age-related macular degeneration (AMD), choroidal neovascularization (CNV), optic neuropathy (ON) and polypoid choroidal vasculopathy (PCV) 9 years from 2012 to 2020; while retinal artery occlusion (RAO) ranked eighth and PCV fell out of the first eight in 2021. Tumor, Eale\'s disease, macular hemorrhage (MH), epiretinal retinal membrane (ERM) and Coat\'s disease had consistent proportions over the years. There was a significant statistical difference in the proportion of disease components over the years from 2012 to 2021(p = 0.000).
CONCLUSIONS: Despite changes in annual distribution, CSC, DR, and RVO consistently ranked as the top three diseases requiring FFA examination. Changes might be related to the development of non-invasive fundus examination instruments and technologies. Indicated that FFA still hold its irreplaceable nature in diagnosing and understanding fundus diseases.