Elderly Subject

老年受试者
  • 文章类型: English Abstract
    老年住院皮肤病是多种多样的。摩洛哥很少有数据描述与平均住院时间(LOS)相关的流行病学概况和因素。我们的目的是识别这些皮肤病并确定与LOS相关的因素。
    Geriatric in-patient dermatoses are diverse. Few data in Morocco describe the epidemiological profile and factors associated with average length of stay (LOS). Our aim was to identify these dermatoses and determine the factors associated with LOS.
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    文章类型: English Abstract
    The superior lumbar hernia or hernia of GRYNFELTT is a rare pathology. It accounts for less than 1.5% of all hernias in the abdomen. An 84 year-old man with upper right lumbar swelling. The clinical examination revealed a right upper lumbar swelling of 5 cm in diameter, soft, gurgling, reducible, impulsive to cough and expansive to intra-abdominal hyperpressure. There was no history of trauma, surgery, tuberculosis or dysuria. The diagnosis of an uncomplicated upper lumbar hernia was retained. Intra-operatively, the sac was dissected up to the hernia opening, separated from the edges of the hernia orifice and discharged. The repair was performed by suturing the back of the hernia opening with a non absorbable thread. The patient was released on day 1 postoperatively. The suites were simple.
    La hernie lombaire supérieure ou hernie de GRYNFELTT est une pathologie rare. Elle représente moins de 1,5% de toutes les hernies de l\'abdomen. Un homme de 84 ans a été reçu pour une tuméfaction lombaire supérieure droite. L\'examen clinique a permis de mettre en évidence une tuméfaction lombaire supérieure droite de 5cm de diamètre, molle, gargouillante, réductible, impulsive à la toux et expansive à l\'hyperpression intra-abdominale. Il n\'y avait pas d\'antécédents de traumatisme, de chirurgie, de tuberculose ou de dysurie. Le diagnostic d\'une hernie lombaire supérieure non compliquée a été retenu. En peropératoire, le sac a été disséqué jusqu\'à l\'orifice herniaire, séparé des bords de l\'orifice herniaire et refoulé. La réparation a été faite par suture en surjet aller-retour des berges de l\'orifice herniaire avec du fil non résorbable. Le malade a été libéré à J1 post-opératoire. Les suites ont été simples.
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  • 文章类型: Case Reports
    双侧硬膜外血肿(EDH)的发生是颅脑外伤的罕见后果,急性对称双侧硬膜外血肿在老年患者中极为罕见。
    方法:我们报告了一例82岁的病人,他从楼梯上摔下来。头皮检查与双顶盖下血肿一致。临床上,他对glascow的13/15分感到困惑。他的脑部扫描显示双侧和对称的顶骨EDH,两个顶骨都有简单的骨折。患者接受了硬脑膜外血肿的两阶段疏散。
    双边EDH病例的管理需要周密的规划,充足的暴露,明智的手术方法和时间管理,取得良好的效果。
    结论:据我们所知,文献中没有报道老年受试者双侧血肿的病例。
    UNASSIGNED: The occurrence of bilateral extradural hematomas (EDH) is a rare consequence of craniocerebral trauma, and acute symmetrical bilateral epidural hematomas are extremely rare even more so in elderly subjects.
    METHODS: We report the case of an 82-year-old patient who had fallen down a flight of stairs. Scalp examination was consistent with a bi-parietal subgaleal hematoma. Clinically, he was confused with a glascow score of 13/15. His brain scan showed bilateral and symmetrical parietal EDH with simple fractures of both parietal bones. The patient underwent a two-stage evacuation of the extra-dural hematomas.
    UNASSIGNED: The management of bilateral EDH cases requires careful planning, adequate exposure, judicious surgical approach and time management for good results.
    CONCLUSIONS: To our knowledge, no case of bilateral hematoma in an elderly subject has been reported in the literature.
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  • 文章类型: English Abstract
    直接口服抗凝剂(DOAC)在其常见适应症中倾向于取代抗维生素K抑制剂(VKAs),老年患者以房颤和静脉血栓栓塞为主。然而,仍然有必要知道如何最好地使用仍然有迹象的VKAs。同样重要的是,不要假设可以无风险地规定AOD,在处理它们时忽略了某些特殊性,特别是在最脆弱的患者有并发症和多种药物。
    Direct oral anticoagulants (DOACs) are tending to supplant antivitamin K inhibitors (VKAs) in their common indications, dominated in elderly patients by atrial fibrillation and venous thromboembolism. Nevertheless, it remains necessary to know how best to use VKAs for which there are still indications. It is also important not to assume that AODs can be prescribed without risk, while ignoring certain particularities in their handling, particularly in the most fragile patients with co-morbidities and multiple medications.
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  • 文章类型: Journal Article
    目的:反向全肩关节置换术(RSA)彻底改变了老年患者肱骨近端骨折(PHF)的治疗方法。关于老年患者术后康复的管理很少或没有共识。与从结节巩固开始到D30的康复相比,从D1的早期康复可以获得更好的功能效果。
    方法:对94例接受PHF手术的患者进行回顾性评估,至少进行2年的放射临床随访。临床评估包括迁移率和四个功能评分:ASES,快速DASH,总常数,加权常数。对前肩X线进行放射学评估,并评估结节的固结。
    结果:平均随访45±19个月(24-88个月)。早期康复与更好的恒定评分显着相关(71.1±17.2vs.56.4±15.8;p<0.001),调整后的Constant评分更好(92.4±14.2vs.80.3±19.5;p<0.001),更好的快速DASH(22.8±19.8vs.36.7±21.3;p<0.01),更好的ASES(78.6±20.2vs.63±22;p<0.001)。
    结论:在创伤学中,RSA的功能结果似乎与结节愈合无关,但与康复无关,以限制手术后肩关节的僵硬。早期康复与更好的临床和功能结果有关,独立于结节结合。
    方法:3,对照病例研究。
    OBJECTIVE: Reverse total shoulder arthroplasty (RSA) has revolutionized the management of proximal humerus fractures (PHF) in the elderly patients. There is few or no consensus regarding to management of postoperative rehabilitation in elderly patients. An early rehabilitation from D1 allowed better functional results compared to rehabilitation started to D30 independently from tuberosities consolidation.
    METHODS: 94 patients operated on for PHF were evaluated retrospectively, with a minimum radio-clinical follow-up of 2 years. Clinical evaluation included mobilities and four functional scores: ASES, quick DASH, gross constant, weighted constant. Radiological evaluation was performed on a frontal shoulder X-ray with evaluation of tuberosities\' consolidation.
    RESULTS: The mean follow-up was 45 ± 19 months (24-88 months). Early rehabilitation was significantly associated with a better Constant Score (71.1 ± 17.2 vs. 56.4 ± 15.8; p < 0.001), better adjusted Constant score (92.4 ± 14.2 vs. 80.3 ± 19.5; p < 0.001), better quick DASH (22.8 ± 19.8 vs. 36.7 ± 21.3; p < 0.01), better ASES (78.6 ± 20.2 vs. 63 ± 22; p < 0.001).
    CONCLUSIONS: In traumatology, functional result of RSA seems not related in tuberosities\' union but in rehabilitation in order to limit postoperative stiffness of operated shoulder. An early rehabilitation is related with better clinical and functional results, independently of tuberosities\' union.
    METHODS: 3, control-case study.
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  • 文章类型: English Abstract
    吞咽障碍,这在老年病学中很常见,与多种病理有关:癌症,中风,神经认知障碍,急性混乱,警惕障碍,等。它们可能会产生严重的后果,因此需要特别注意。从医生对疾病的鉴定来看,护士,看护者,语言治疗评估,通过营养师对饮食的适应,吞咽障碍的管理关系到所有医疗和辅助医务人员。本文的目的是提出现有的主要建议,以促进患者的喂养,尽管存在这些疾病。
    Swallowing disorders, which are frequent in geriatrics, are linked to multiple pathologies: cancer, stroke, neurocognitive disorders, acute confusion, vigilance disorders, etc. They can have serious consequences and therefore require special care. From the identification of the disorders by the doctor, the nurse, the caregiver, to the speech therapy assessment, through the adaptation of the diet by the dietician, the management of swallowing disorders concerns all the medical and paramedical staff. The aim of this article is to present the main existing recommendations to promote the patient\'s feeding despite the presence of these disorders.
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  • 文章类型: English Abstract
    送货上门已经扩展到所有零售部门。在Covid-19大流行的第一波中,许多希望在家中接受药物治疗的患者都与药剂师接洽。问题是这种发展是可持续的还是仅仅是周期性的。
    Home delivery has expanded across all retail sectors. During the first waves of the Covid-19 pandemic, pharmacists were approached by many of their patients who wanted to receive their medications at home. The question is whether this development is sustainable or merely cyclical.
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  • 文章类型: Journal Article
    背景:诺比林对各种阿尔茨海默病动物模型的认知功能具有有益作用。本研究旨在研究来自C.depressa果皮的富含金黄素的提取物的组合食品对健康的老年受试者的益处和安全性。
    方法:含诺比林的测试食品(Nobilex®)包含高纯度的诺比林素粉,并结合K.parviflora的干燥根粉和日本血吸虫的干燥铅粉,每天一次,持续16周。日本版本的Wechsler内存缩放修订(WMS-R)用作评估全局内存的主要评估项目。分析来自方案匹配的群体(每个方案集:PPS)(n=108)的数据。
    结果:在WMS-R指数中的“一般记忆”或“视觉记忆”得分在含诺比林的测试食物组中明显高于安慰剂组。试验食品组WMS-R总评分的差异(9.0±7.20)明显高于安慰剂组(5.9±7.70)。WMS-R检验的年龄分层分析显示,年龄≤74岁的受试者与整个受试者人群的变化相似。在涉及MMSE-J得分在24至28之间的受试者的分层分析中,WMS-R中的“形象记忆”子量表得分在测试食物组中明显高于安慰剂组。
    结论:目前的结果表明,含诺比林的测试食物有利于改善健康老年受试者的记忆功能障碍。
    BACKGROUND: Nobiletin exerts beneficial effects on cognitive function in various animal models of Alzheimer\'s disease. The present study aimed to investigate the benefits and safety of a combination food of nobiletin-rich extract from C. depressa peel for healthy elderly subjects.
    METHODS: The nobiletin-containing test food (Nobilex®) comprised high-purity nobiletin powder combined with dried root powder of K. parviflora and dried lead powder of P. japonicum and was administered to elderly Japanese subjects once a day for 16 weeks. The Japanese version of the Wechsler Memory Scaled-Revised (WMS-R) was used as a primary evaluation item for the assessment of global memory. Data from a protocol-matched population (Per Protocol Set: PPS) (n = 108) were analyzed.
    RESULTS: The scores of \"general memory\" or \"visual memory\" in the indices of WMS-R were significantly higher in the nobiletin-containing test food group than in the placebo group. The difference in the total WMS-R score was significantly higher in the test-food group (9.0 ± 7.20) than in the placebo group (5.9 ± 7.70). An age-stratified analysis of the WMS-R test showed similar changes in subjects aged ≦74 years to those in the overall subject population. In the stratified analysis involving subjects with an MMSE-J score of between 24 and 28, the \"figural memory\" subscale score in WMS-R was significantly higher in the test food group than in the placebo group.
    CONCLUSIONS: The present results indicate that the nobiletin-containing test food is beneficial for improving memory dysfunction in healthy elderly subjects.
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  • 文章类型: Journal Article
    老年人的恐慌症是一种研究不足的疾病,尽管与严重的功能障碍有关,该人群的生活质量下降,自杀风险增加。由于缺乏针对这种脆弱人群的国家和国际准则,这种疾病可能未得到充分诊断,有时治疗不足。很少有治疗性试验专门针对老年人惊恐障碍的药物和心理治疗的疗效和耐受性,目前检测和管理这种疾病的方法主要基于专家意见或从年轻成年人的可用数据推断。本报告旨在提供有关老年人惊恐障碍的药物和心理治疗的最新知识的总结,并提出一种医学治疗算法,它应该被视为一种可能有助于选择治疗的工具,特别是对于患有恐慌症的难治性老年患者。这里的主要结果是强调抗抑郁治疗,如选择性5-羟色胺再摄取抑制剂(SSRI),限制使用苯二氮卓类药物,对药物相互作用的认识和心理治疗的重要性,如认知行为治疗(CBT)。
    Panic disorder in the elderly is an understudied disorder, despite being associated with substantial functional impairment, a diminished quality of life and an increased suicide risk in this population. This disorder is likely to be underdiagnosed and sometimes inadequately treated due to the absence of national and international guidelines for this vulnerable population. Few therapeutic trials have specifically focused on the efficacy and tolerability of pharmacological and psychotherapy treatments for panic disorder in the elderly and current approaches to detect and manage this disorder are mainly based on expert opinions or extrapolation from data available on younger adults. This report aims to provide a summary of current knowledge on pharmacological and psychotherapeutic treatments for panic disorder in the elderly and to propose a medical treatment algorithm, which should be viewed as a tool that may contribute to the choice of treatment, especially for treatment-resistant older patients with panic disorder. The main results here are the emphasis on antidepressant treatment, such as selective serotonin reuptake inhibitor (SSRI), restricted benzodiazepine usage, awareness of drug interactions and the importance of psychotherapy such as cognitive behavioural therapy (CBT).
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  • 文章类型: Case Reports
    急性冠状动脉综合征(ACS)是急诊室中经常遇到的一种病理,尤其是老年人。尽管通常是异质和非典型的表现,但护理人员必须知道如何识别ACS。管理应包括对患者的全面评估,以决定对患者的最佳管理。
    Acute coronary syndrome (ACS) is a pathology frequently encountered in emergency rooms, especially in the elderly. Caregivers must know how to recognize an ACS despite an often heterogeneous and atypical presentation. Management should include an overall assessment of the patient in order to decide on the best management for the patient.
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