虽然抗球虫药物能有效控制球虫病,在动物生产中需要减少对抗菌药物的依赖,这导致了对替代化合物的探索。本研究旨在测试五种不同的饮食处理,以抵消球虫病对肉鸡健康和性能的负面影响。将1天大的雄性Ross308肉鸡(n=960)随机分配到八种治疗方法之一,每个治疗有六个笼子(20只鸟/笼子)。从d0-10向处理(Trt)1-5的肉鸡的日粮中加入合生元。从d10-28,给Trt1和Trt2的鸟喂食合生元,而Trt3的鸟是用谷氨酰胺喂养的,用β-葡聚糖和甜菜碱的组合饲喂Trt4和Trt5的禽类。从d28-35开始,用合生元喂养Trt1的鸟类,而Trt2-4的鸟接受谷氨酰胺的饮食,和Trt5的鸟被喂食非补充饮食。阳性对照组(PC;Trt6)的鸟类饲喂补充了抗球虫(Decoquinate)的标准饮食。向攻击的阴性对照(NCchall;Trt7)和非攻击的阴性对照(NC)Trt8饲喂标准饮食而没有抗球虫或其他饮食处理。在7天(d)的年龄,所有鸟类都接种了1.023、115和512个孢子形成的卵囊。E.最大值,还有E.Tenella,分别,除了Trt8。体重增加(BWG),饲料摄入量,和饲料转化率在每个饲喂阶段(d0-10,d10-28和d28-35)和整个实验期(d0-35)进行评估。卵囊脱落,艾美球虫病变评分,盲肠长度,在d13、d22、d28和d35时评估相对体重。此外,在d9和d17确定卵囊脱落。在d27和d34评估垫料质量,在d34评估脚垫损伤。在启动器(d0-10)和整理器(d28-35)期间,治疗之间的表现没有差异。在种植期(d10-28),在所有处理中,Trt6(PC)和Trt8(NC)鸡具有最高的BWG(P<0.001)。饮食治疗对窝质量和足垫病变的严重程度没有影响。在PC组(Trt6)中,发现卵囊排泄和病变评分低。当比较Trt1-5与NCchall(Trt7)时,所有治疗均未显著降低卵囊排出量或病变评分。总之,在这个实验中,与PC组(Trt6)相比,在表现或减少艾美耳球虫卵囊脱落或病变评分方面,没有一种饮食治疗表现相似或更好.
Although anticoccidials effectively control coccidiosis, a needed reduction in the reliance on antimicrobials in animal production leads to the exploration of alternative compounds. The present study aimed to test five different dietary treatments to counteract the negative impact of coccidiosis on broiler chickens\' health and performance. 1-day-old male Ross 308 broilers (n = 960) were randomly assigned to one of eight treatments, with six cages per treatment (20 birds/cage). To the diet of the broiler chickens of treatments (Trt) 1-5, a synbiotic was added from d0-10. From d10-28, birds of Trt1 and Trt2 were fed synbiotics, whereas birds of Trt3 were fed diets with glutamine, and birds of Trt4 and Trt5 were fed diets with a combination of β-glucans and betaine. From d28-35 onwards, birds of Trt1 were fed a diet with a synbiotic, whereas birds of Trt2-4 received diets with glutamine, and birds of Trt5 were fed a non-supplemented diet. Birds of the positive control group (PC; Trt6) were fed a standard diet supplemented with an anticoccidial (Decoquinate). The challenged negative control (NCchall; Trt7) and non-challenged negative control (NC) Trt8 were fed a standard diet without anticoccidial or other dietary treatment. At 7 days (d) of age, all birds were inoculated with 1 023, 115, and 512 sporulated oocysts of E. acervulina, E. maxima, and E. tenella, respectively, except for Trt8. Body weight gain (BWG), feed intake, and feed conversion ratio were assessed for each feeding phase (d0-10, d10-28 and d28-35) and overall experimental period (d0-35). Oocyst shedding,
Eimeria lesion scores, cecal length, and relative weight were assessed at d13, d22, d28 and d35. Additionally, oocyst shedding was determined at d9 and d17. Litter quality was evaluated at d27 and d34, and footpad lesions at d34. During the starter (d0-10) and finisher (d28-35) periods, performance did not differ between the treatments. During the grower period (d10-28), Trt6 (PC) and Trt8 (NC) chickens had the highest BWG of all treatments (P < 0.001). Dietary treatment had no effect on litter quality and severity of footpad lesions. In the PC group (Trt6), low oocyst excretion and lesion scores were found. When comparing Trt1-5 with NCchall (Trt7), none of the treatments significantly reduced oocyst output or lesion scores. In conclusion, in this experiment, none of the dietary treatments performed similar or better compared to the PC group (Trt6) regarding performance or reducing
Eimeria oocyst shedding or lesion scores.