帕金森病(PD)是一种常见的神经退行性疾病,约占60岁及以上人群的1-3%。除了电机困难,PD也有视觉障碍,包括深度感知,基底神经节功能异常,多巴胺缺乏.感知深度的能力降低与该人群跌倒的风险增加有关。本文的目的是确定PD患者的视觉处理障碍是否通过视错觉(VI)任务的非典型表现而表现出来。这种见解将促进对PD中高级感知的理解,以及表明多巴胺缺乏和基底节病理生理学在VIs易感性中的作用。28名PD患者组(Mage=63.46,SD=7.55)和28名神经典型对照(Mage=63.18,SD=9.39)年龄匹配,一般认知能力(记忆,算术,注意,语言),情绪对艾宾浩斯有反应,Ponzo,和Müller-Lyer在基于计算机的任务中的幻想。我们的结果表明,PD和神经典型组之间的VI易感性没有可靠的差异。在PD的早期到中期,基底神经节的异常和多巴胺缺乏不太可能参与自上而下的处理或深度感知,两者都被认为与VI易感性有关。此外,PD患者经历的深度相关问题(例如,跌倒风险增加)可能不会与VI相同的认知机制。需要进一步的研究来调查在PD中是否会影响更明确的虚幻深度表现,这可能有助于理解PD的深度处理缺陷。
Parkinson\'s disorder (PD) is a common neurodegenerative disorder affecting approximately 1-3% of the population aged 60 years and older. In addition to motor difficulties, PD is also marked by visual disturbances, including depth perception, abnormalities in basal ganglia functioning, and dopamine deficiency. Reduced ability to perceive depth has been linked to an increased risk of falling in this population. The purpose of this paper was to determine whether disturbances in PD patients\' visual processing manifest through atypical performance on visual illusion (VI) tasks. This insight will advance understanding of high-level perception in PD, as well as indicate the role of dopamine deficiency and basal ganglia pathophysiology in VIs susceptibility. Groups of 28 PD patients (Mage = 63.46, SD = 7.55) and 28 neurotypical controls (Mage = 63.18, SD = 9.39) matched on age, general cognitive abilities (memory, numeracy, attention, language), and mood responded to Ebbinghaus, Ponzo, and Müller-Lyer illusions in a computer-based task. Our results revealed no reliable differences in VI susceptibility between PD and neurotypical groups. In the early- to mid-stage of PD, abnormalities of the basal ganglia and dopamine deficiency are unlikely to be involved in top-down processing or depth perception, which are both thought to be related to VI susceptibility. Furthermore, depth-related issues experienced by PD patients (e.g., increased risk for falling) may not be subserved by the same cognitive mechanisms as VIs. Further research is needed to investigate if more explicit presentations of illusory depth are affected in PD, which might help to understand the depth processing deficits in PD.