Ear Canal

耳道
  • 文章类型: Journal Article
    军事人员中耳塞的不良利用可能是由于闭塞效应(OE)引起的不适。OE发生在耳塞堵塞耳道时,从而改变骨传导(BC)听力并放大来自佩戴者的生理噪声。需要理解和减少人耳中的OE。采用包括3腔螺旋耳蜗的人耳的3D有限元模型来模拟由泡沫和气凝胶耳塞引起的OE。在耳道入口处施加90dB声压,并且施加BC声音作为耳道骨壁的振动。该模型报告了耳道压力以及有无耳塞的the脚底板和耳蜗基底膜的位移。没有BC刺激,泡沫耳塞比气凝胶耳塞显示更大的压力衰减。然而,泡沫耳塞结果受BC刺激的影响更大,最大声压增加34dB,与气凝胶耳塞增加21.0dB相比。气凝胶耳塞的低OE证明了其作为耳塞材料的前景。该模型的未来工作将检查耳蜗中的BC声音传输。
    Poor utilization of earplugs among military personnel may be due to discomfort caused by the occlusion effect (OE). The OE occurs when an earplug occludes the ear canal, thereby changing bone conduction (BC) hearing and amplifying physiological noises from the wearer. There is a need to understand and reduce the OE in the human ear. A 3D finite element model of the human ear including a 3-chambered spiral cochlea was employed to simulate the OE caused by foam and aerogel earplugs. 90 dB sound pressure was applied at the ear canal entrance and BC sound was applied as vibration of the canal bony wall. The model reported the ear canal pressure and the displacements of the stapes footplate and cochlear basilar membrane with and without earplugs. Without BC stimulation, the foam earplug showed a greater pressure attenuation than the aerogel earplug. However, the foam earplug results were more affected by BC stimulation, with a maximum sound pressure increase of 34 dB, compared to the 21.0 dB increase with the aerogel earplug. The aerogel earplug\'s lower OE demonstrates its promise as an earplug material. Future work with this model will examine BC sound transmission in the cochlea.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Case Reports
    本报告介绍了罕见的支气管腺癌,并在外耳道中发生了初始转移。病人,一位有膀胱尿路上皮癌病史的64岁男性,最初表现为持续性右外耳道炎。耳镜检查发现肿块阻塞了右外耳道。颞骨计算机断层扫描显示肿块完全阻塞了右外耳道并延伸到中耳。活检显示支气管起源的低分化腺癌,通过细胞角蛋白7和甲状腺转录因子-1的免疫组织化学染色阳性证实。进一步的成像显示肺部有一个大的肿瘤肿块,累及纵隔和实质,伴随着癌性淋巴管炎和脑转移。原发性肺肿瘤的组织病理学检查证实为低分化腺癌,其特征与外耳道转移相似。肿瘤分期为T4N2M1c,患者接受了局部外束放疗和化疗。
    This report presents a rare case of bronchogenic adenocarcinoma with initial metastasis in the external auditory canal. The patient, a 64-year-old man with a history of bladder urothelial carcinoma, initially presented with a persistent right otitis externa. Otoscopic examination revealed a mass obstructing the right external auditory canal. The temporal bone computed tomography scan revealed a mass that completely obstructed the right external auditory canal and extended into the middle ear. A biopsy showed a poorly differentiated adenocarcinoma of bronchogenic origin, confirmed by positive immunohistochemical staining for cytokeratin 7 and Thyroid transcription factor-1. Further imaging revealed a large tumor mass in the lung involving the mediastinum and parenchyma, along with carcinomatous lymphangitis and cerebral metastasis. Histopathological examination of the primary lung tumor confirmed a poorly differentiated adenocarcinoma with similar features to the metastasis in the external auditory canal. The tumor was staged as T4N2M1c, and the patient underwent local external-beam radiation therapy with chemotherapy.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    目的:独立研究长期助听器使用培养物的微生物变化。
    方法:横断面研究。
    方法:50名长期助听器使用者和80名无症状耳朵的志愿者对照。
    方法:使用无DNA拭子进行外耳道(EAC)采样。
    方法:用16SrRNA基因的扩增子测序研究样品中的微生物群落。
    结果:最终分析包含48个助听器用户,59个控件。由于序列计数低,24个样本被排除在外,最近使用抗菌药物和/或皮质类固醇,最近的寒冷,或健康状况缺失。各组在细菌多样性上显示出显着差异(βdiv。,p=0.011),助听器使用者的物种丰富度低于对照组(alphadiv。,p<0.01)。两组中最常见的发现是耳葡萄球菌,同种异体球菌中耳炎,粉刺杆菌,杆菌属,和未分类的葡萄球菌。助听器使用者的样本比对照样本呈现更多的结核杆菌。常见的EAC病原体,如金黄色葡萄球菌或铜绿假单胞菌很少见。
    结论:长期使用助听器会降低细菌多样性并调节EAC微生物组。这些变化主要影响共生。多样性降低可能使个体容易受到EAC条件的影响,需要更多的研究。
    OBJECTIVE: To investigate the microbial changes of long-term hearing aid use culture independently.
    METHODS: Cross-sectional study.
    METHODS: Fifty long-term hearing aid users and 80 volunteer controls with asymptomatic ears.
    METHODS: External auditory canal (EAC) sampling with DNA-free swabs.
    METHODS: Microbial communities in the samples were investigated with amplicon sequencing of the 16S rRNA gene.
    RESULTS: The final analysis contained 48 hearing aid users, 59 controls. Twenty-four samples were excluded because of low sequence count, recent use of antimicrobials and/or corticosteroids, recent cold, or missing health status. The groups showed significant differences in bacterial diversity (beta div., p = 0.011), and hearing aid users showed lower species richness than the control group (alpha div., p < 0.01). The most frequent findings in both groups were Staphylococcus auricularis , Alloiococcus otitis , Cutibacterium acnes , Corynebacterium otitidis , and Staphylococcus unclassified sp. Hearing aid users\' samples presented more Corynebacterium tuberculostearicum than the control samples. Common EAC pathogens, such as Staphylococcus aureus or Pseudomonas aeruginosa were rare.
    CONCLUSIONS: Long-term hearing aid use lowers bacterial diversity and modulates the EAC microbiome. The changes mostly affect commensals. Lowered diversity may predispose individuals to EAC conditions and needs more research.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Journal Article
    Trichoblastoma(TB) is a rare germ cell skin adnexal tumor of the hair, and it is a rare follicular tumor of the skin that differentiates from the hair germ epithelium and is often regarded as a benign skin tumorHowever, it is poorly confined and has a local infiltrative growth pattern. tb occurs in the head and neck region, especially in the face, and presents clinically as a slow growing, well-defined and elevated nodule. TB is routinely treated surgically. Due to the lack of universally accepted treatment guidelines or protocols, the recurrence rate after surgery is high, which makes clinical cure more difficult. In this study, a 65-year-old female patient was found to have a swelling with recurrent rupture and pus flow from the right external auditory canal opening and the auricular cavity. After initial misdiagnosis as otitis externa, she was treated with conventional anti-infective therapy, but her symptoms did not resolve and gradually worsened before coming to our hospital. The condition presented in this case is relativelyrare,therepre,timely and accurate diagnosis and treatment are crucial for prognosis improvement of such diseases.
    摘要: 毛母细胞瘤(trichoblastoma,TB)是一种罕见的毛发生殖细胞皮肤附件肿瘤,罕见的皮肤滤泡肿瘤,分化于毛胚上皮,常被视为良性皮肤肿瘤,但局限性差且具有局部浸润性生长模式。TB好发于头部和颈部区域,尤其是面部,临床表现为生长缓慢、边界清晰及隆起的结节。TB常规以手术治疗为主,由于目前缺乏普遍接受的治疗指南或方案,术后复发率高,为临床治愈增加了一定的难度。本研究报道1例65岁女性患者,发现右侧外耳道口及耳甲腔肿物并反复破溃流脓,最初误诊为外耳道炎,以常规抗感染治疗,症状未缓解并逐渐加重后来我院就诊。该病例所展现的病症极为罕见,因此,及时且准确的诊断与治疗对此类疫病的诊疗和预后至关重要。.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Journal Article
    马拉色菌酵母属于多种温血动物的正常皮肤微生物群。然而,它们在牛中的意义仍然知之甚少。在本研究中,通过细胞学评估了20头健康奶牛的外耳道的分枝杆菌群,文化,PCR,和下一代测序。通过细胞学和PCR在15头牛中检测到马拉色菌的存在。宏基因组分析表明,子囊菌是主要的门,而厚皮杆菌是主要的物种。检测到马拉色菌属型131的丰度较低。在样品中没有检测到M.nana和马匹。
    通过细胞学评估了健康奶牛外耳道的分枝杆菌群,文化,PCR,和NGS。通过细胞学和PCR检测马拉色菌的存在。子囊菌是主要门,厚皮杆菌是主要物种。在样品中还检测到马拉色菌属型131。
    Malassezia yeasts belong to the normal skin microbiota of a wide range of warm-blooded animals. However, their significance in cattle is still poorly understood. In the present study, the mycobiota of the external ear canal of 20 healthy dairy Holstein cows was assessed by cytology, culture, PCR, and next-generation sequencing. The presence of Malassezia was detected in 15 cows by cytology and PCR. The metagenomic analysis revealed that Ascomycota was the predominant phylum but M. pachydermatis the main species. The Malassezia phylotype 131 was detected in low abundance. Nor M. nana nor M. equina were detected in the samples.
    The mycobiota of the external ear canal of healthy cows was assessed by cytology, culture, PCR, and NGS. The presence of Malassezia was detected by cytology and PCR. Ascomycota was the main phylum and M. pachydermatis the main species. The Malassezia phylotype 131 was also detected in the samples.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Journal Article
    假设平面波,耳道声量,统称为宽带声导纳(WAI),经常用于研究和临床,以评估中耳的导电状态。次要应用包括在向耳朵传递刺激和测量耳声发射时补偿耳道声学。然而,耳道本质上是不均匀的,并通过圆锥形鼓膜(TM)以倾斜的角度终止,因此可能混淆WAI数量表征中耳状态的能力。本文研究了TM方向和形状对使用WAI在人耳中表征中耳的孤立可能的混淆作用。也就是说,不考虑耳道的不均匀几何形状,除了由TM取向和形状引起的。这是使用由集总单元和有限元中耳模型终止的均匀耳道的有限元模型来实现的。此外,研究了对刺激和反向传播量的影响,包括寻求近似TM声压的量的物理意义。结果表明,TM取向对WAI量的影响相对较小,除了10kHz以上的明显延迟,进一步影响一些刺激和反向传播量。
    Assuming plane waves, ear-canal acoustic quantities, collectively known as wideband acoustic immittance (WAI), are frequently used in research and in the clinic to assess the conductive status of the middle ear. Secondary applications include compensating for the ear-canal acoustics when delivering stimuli to the ear and measuring otoacoustic emissions. However, the ear canal is inherently non-uniform and terminated at an oblique angle by the conical-shaped tympanic membrane (TM), thus potentially confounding the ability of WAI quantities in characterizing the middle-ear status. This paper studies the isolated possible confounding effects of TM orientation and shape on characterizing the middle ear using WAI in human ears. That is, the non-uniform geometry of the ear canal is not considered except for that resulting from the TM orientation and shape. This is achieved using finite-element models of uniform ear canals terminated by both lumped-element and finite-element middle-ear models. In addition, the effects on stimulation and reverse-transmission quantities are investigated, including the physical significance of quantities seeking to approximate the sound pressure at the TM. The results show a relatively small effect of the TM orientation on WAI quantities, except for a distinct delay above 10 kHz, further affecting some stimulation and reverse-transmission quantities.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    目的:穿孔边缘的修剪和外耳道(EAC)的填塞是修复慢性穿孔的基础方法。这项研究的目的是比较手术时间,移植结果,听力改善,以及在儿童中有或没有修剪穿孔边缘和EAC填塞的情况下内窥镜软骨下膜成形术的并发症。
    方法:前瞻性,随机研究。
    方法:三级转诊中心。
    方法:将12岁以上慢性穿孔的小儿患者随机分为两组:穿孔切缘和EAC填塞(TPME)组或不穿孔切缘和EAC填塞(NTPME)组。操作时间,移植成功率,听力改善,比较两组并发症发生情况。
    结果:52名患者最终被纳入研究。TPME组平均手术时间为31.4±4.2min,NTPME组平均手术时间为23.6±1.7min,差异有统计学意义(P<0.01)。TPME组和NTPME组的听觉饱满度率显着差异(P=0.000)。所有参与者均随访12个月;两组之间的移植成功率没有显着差异(88.5%vs.96.2%;P=0.603)。没有患者发生粘连性中耳炎。在术前和术后测量之间,TPME组的平均气-骨间隙改善了10.2±2.8dB,NTPME组的平均气-骨间隙改善了11.6±0.7dB;这在两组中是显著的(P<0.001)。
    结论:与TPME技术相比,内窥镜软骨下膜鼓膜成形术NTPME缩短了手术时间,避免了听觉饱胀和EAC不适;但是,两种修复儿童大穿孔的技术在移植成功率和听力改善方面具有可比性。
    OBJECTIVE: Trimming of perforation margins and external auditory canal (EAC) packing are basic procedures in underlay myringoplasty for repairing chronic perforations. The objective of this study was to compare the operation time, graft outcome, hearing improvement, and complications of endoscopic cartilage underlay myringoplasty with and without trimming of perforation margins and EAC packing in children.
    METHODS: Prospective, randomized study.
    METHODS: Tertiary referral center.
    METHODS: Pediatric patients older than 12 years with chronic perforations were randomly divided into two groups: myringoplasty with trimming of perforation margin and EAC packing (TPME) group or no trimming of perforation margin and EAC packing (NTPME) group. The operation time, graft success rate, hearing improvement, and complications were compared between the two groups.
    RESULTS: Fifty-two patients were ultimately included in the study. The mean operation time was 31.4 ± 4.2 min in the TPME group and 23.6 ± 1.7 min in the NTPME group; the difference was significant (P < 0.01). The rate of aural fullness significantly differed between the TPME and NTPME groups (P = 0.000). All participants were followed up for 12 months; the graft success rate did not significantly differ between the groups (88.5% vs. 96.2%; P = 0.603). No patients developed adhesive otitis media. Between the preoperative and postoperative measurements, the mean air-bone gap improved by 10.2 ± 2.8 dB in the TPME group and 11.6 ± 0.7 dB in the NTPME group; this was significant (P < 0.001) in both groups.
    CONCLUSIONS: Endoscopic cartilage underlay myringoplasty NTPME shorted the operation time and avoided aural fullness and EAC discomfort compared with the TPME technique; however, graft success and hearing improvement were comparable between the two techniques for repairing large perforations in children.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Journal Article
    背景:取耳部印模是一种微创手术。对现有文献的回顾表明,尚未开发出扫描耳朵的非接触式方法。我们建议建立外耳特征与耳道之间的相关性,并通过这种概念证明来开发用于捕获和预测耳道信息的原型和算法。
    方法:我们开发了一种新颖的原型,该原型使用结构光成像来捕获耳朵的外部图像。使用传统方法获得的现有耳印象图像的大型数据库,进行了相关分析并建立。设计了一种深度神经网络来构建预测算法。接受助听器评估的患者采用了两种耳朵印模方法。我们评估了他们的主观反馈,并确定从印模技术获得的图像之间是否存在足够接近的客观匹配。
    结果:开发并部署了一个原型进行试验,大多数参与者对这种新颖的耳朵印象采集方法感到满意。从拍摄的图像可以获得耳道的部分匹配,并且应用于少数样本图像的预测算法在建立概念证明的情况下处于良好的误差标准之内。
    结论:有必要进行进一步的研究,以加强算法的预测能力,并确定最佳的原型成像位置,以便可以获得足够的耳道信息以进行三维打印。耳朵的印象可能会被自动化,与当天三维打印的耳模提供及时访问的可能性。
    BACKGROUND: Taking an ear impression is a minimally invasive procedure. A review of existing literature suggests that contactless methods of scanning the ear have not been developed. We proposed to establish a correlation between external ear features with the ear canal and with this proof of concept to develop a prototype and an algorithm for capturing and predicting ear canal information.
    METHODS: We developed a novel prototype using structured light imaging to capture external images of the ear. Using a large database of existing ear impression images obtained by traditional methods, correlation analyses were carried out and established. A deep neural network was devised to build a predictive algorithm. Patients undergoing hearing aid evaluation undertook both methods of ear impression-taking. We evaluated their subjective feedback and determined if there was a close enough objective match between the images obtained from the impression techniques.
    RESULTS: A prototype was developed and deployed for trial, and most participants were comfortable with this novel method of ear impression-taking. Partial matching of the ear canal could be obtained from the images taken, and the predictive algorithm applied for a few sample images was within good standard of error with proof of concept established.
    CONCLUSIONS: Further studies are warranted to strengthen the predictive capabilities of the algorithm and determine optimal prototype imaging positions so that sufficient ear canal information can be obtained for three-dimensional printing. Ear impression-taking may then have the potential to be automated, with the possibility of same-day three-dimensional printing of the earmold to provide timely access.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    这项研究的目的是探索双峰听觉和非侵入性电刺激耳朵以减轻音调的潜力,在一项小型初步试验中调查的躯体性耳鸣(11名参与者)。
    听觉刺激采取了针对每个参与者的耳鸣感知定制的短“缺口噪声”爆发的形式。同时脉冲电刺激,旨在促进神经可塑性,通过放置在相对耳朵中的水凝胶电极递送。
    经过6周的干预期,平均耳鸣功能指数(TFI)和耳鸣主要功能问卷(TPFQ)评分与研究人群的临床意义改善一致。TFI和TPFQ改善的幅度和效果大小与其他最近使用不同听觉和电刺激参数的双峰治疗研究中报道的那些相当。
    鉴于样本量较小,我们的结果应被视为初步的,缺乏交叉数据,和小主题池。当与其他最近的双峰治疗结果一起考虑时,我们确实相信,双峰刺激对耳鸣患者有治疗益处,有可能帮助一些耳鸣,具有多种刺激参数和电极位置。
    https://doi.org/10.23641/asha.25444546。
    UNASSIGNED: The aim of this study was to explore the potential for bimodal auditory and noninvasive electrical stimulation at the ears to alleviate tonal, somatic tinnitus that was investigated in a small preliminary trial (11 participants).
    UNASSIGNED: Auditory stimulation took the form of short \"notched noise\" bursts customized to each participant\'s tinnitus percept. Simultaneous pulsed electrical stimulation, intended to facilitate neuroplasticity, was delivered via hydrogel electrodes placed in opposite ears.
    UNASSIGNED: After a 6-week intervention period, average Tinnitus Functional Index (TFI) and Tinnitus Primary Function Questionnaire (TPFQ) scores were consistent with clinically meaningful improvements in the study population. Magnitudes and effect sizes of improvements in TFI and TPFQ are comparable to those reported in other recent bimodal therapy studies using different auditory and electrical stimulation parameters.
    UNASSIGNED: Our results should be considered preliminary given the small sample size, lack of crossover data, and small subject pool. When considered alongside other recent bimodal therapy results, we do believe that there are therapeutic benefits of bimodal stimulation for tinnitus sufferers that have the potential to help some with tinnitus, with a variety of stimulation parameters and electrode placements.
    UNASSIGNED: https://doi.org/10.23641/asha.25444546.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Journal Article
    今天,定制助听器包括将硅胶注入患者的耳朵以产生耳道模具。这些随后被3D扫描以创建数字耳道印模。然而,在使用数字印象之前,它们需要大量的手动3D编辑工作。在这篇文章中,我们提出了预处理耳道印象的计算方法。目的是创建自动化工具来辅助助听器设计,制造和拟合过程以及规范解剖数据,以协助研究外耳道的形态。该方法包括将印象的惯用手分为左耳和右耳类型,将几何形状定向到相同的坐标系上,并去除由硅胶模具引入的外来伪影。我们研究了使用卷积神经网络来执行这些语义任务,并使用3000个耳道印象的数据集评估其准确性。事实证明,神经网络在执行这些任务方面非常有效,分类的调整准确率为95.8%,配准中20°角误差为92.3%,分割中93.4%的交点超过并集。
    Today, fitting bespoke hearing aids involves injecting silicone into patients\' ears to produce ear canal molds. These are subsequently 3D scanned to create digital ear canal impressions. However, before digital impressions can be used they require a substantial amount of effort in manual 3D editing. In this article, we present computational methods to pre-process ear canal impressions. The aim is to create automation tools to assist the hearing aid design, manufacturing and fitting processes as well as normalizing anatomical data to assist the study of the outer ear canal\'s morphology. The methods include classifying the handedness of the impression into left and right ear types, orienting the geometries onto the same coordinate system sense, and removing extraneous artifacts introduced by the silicone mold. We investigate the use of convolutional neural networks for performing these semantic tasks and evaluate their accuracy using a dataset of 3000 ear canal impressions. The neural networks proved highly effective at performing these tasks with 95.8% adjusted accuracy in classification, 92.3% within 20° angular error in registration and 93.4% intersection over union in segmentation.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

公众号