目的:前庭系统与情绪处理神经元回路密切相关。双侧前庭病(BVP)患者,慢性前庭功能丧失,与发作性眩晕/头晕(v/d)相比,精神病合并症和与眩晕相关的焦虑(VRA)的发生率显着降低。这项研究旨在评估BVP患者与发作性v/d患者在VRA方面是否存在差异,一般焦虑,以及对身体和健康的认知。
方法:这项横断面研究涉及202例发作性v/d患者的子样本(即,前庭性偏头痛,前庭阵发性障碍,或梅尼埃病)和43例BVP患者。所有患者均接受标准化神经/神经检查,结构化临床访谈(SCID-I),和自我报告问卷,如眩晕障碍问卷(VHQ),贝克焦虑量表(BAI),来自状态-特质焦虑量表(STAI-T)的特质焦虑,和关于身体和健康的认知问卷(CABAH)。非参数检验用于分析。由于多次测试,显著性水平设置为p≤.008。
结果:偶发性v/d患者的VRA水平高于BVP患者。然而,这一差异无统计学意义(p=.04;r=0.15,效应小).此外,与发作性v/d患者相比,BVP患者报告了更多的灾难性认知(p<.001;r=0.25,影响小)和身体虚弱(p=.003;r=0.22,影响小)。v/d患者和BVP患者之间的一般焦虑水平(BAI和STAI-T)没有差异。
结论:发作性v/d和BVP患者在评估(认知)方面存在差异。VRA(主观感觉)差异无统计学意义。这些初步结果是使用成分方法来讨论情绪的。
OBJECTIVE: The vestibular system is closely connected to emotion-processing neuronal circuits. Patients with bilateral vestibulopathy (BVP), a chronic loss of vestibular function, show remarkably lower rates of psychiatric comorbidities and vertigo-related anxiety (VRA) than those with episodic vertigo/dizziness (v/d). This study aimed to evaluate whether patients with BVP differ from those with episodic v/d in terms of VRA, general anxiety, and cognitions about body and health.
METHODS: This cross-sectional study involved a subsample of 202 patients with episodic v/d (i.e., vestibular migraine, vestibular paroxysmia, or Menière\'s disease) and 43 patients with BVP. All patients underwent standardised neurological/neurotological examinations, structured clinical interviews (SCID-I), and self-report questionnaires, such as the Vertigo Handicap Questionnaire (VHQ), Beck Anxiety Inventory (BAI), Trait Anxiety from the State-Trait-Anxiety Inventory (STAI-T), and Cognitions About Body and Health questionnaire (CABAH). Non-parametric tests were used for analysis. Due to multiple testing, the significance level was set at p ≤ .008.
RESULTS: Patients with episodic v/d exhibited higher VRA levels than those with BVP. However, this difference was not statistically significant (p = .04; r = 0.15, small effect). Additionally, patients with BVP reported more catastrophizing cognitions (p < .001; r = 0.25, small effect) and bodily weakness (p = .003; r = 0.22, small effect) compared to those with episodic v/d. There were no differences in general anxiety levels (BAI and STAI-T) between patients with v/d and those with BVP.
CONCLUSIONS: Patients with episodic v/d and BVP differed in their appraisal (cognition). The difference in VRA (subjective feeling) was not statistically significant. These preliminary results are discussed using a component approach to emotions.