我们先前在2011年的研究报告了在20种海洋和淡水鱼中检测到BPA和PFAA。有新的证据表明BPA/PFAA对动物的代谢干扰作用,本研究旨在提供时间趋势分析,以确定20种市售香港鱼类中当前的PFAA和BPA浓度。由于大多数国家都禁止制造和使用BPA,BPA替代品的引入最近已被纳入市场。因此,BPB的浓度,测定BPF和BPS。在本研究中,所有淡水和海水鱼类样品均显示出BPA的定量浓度[>定量限值(LOQ<0.5ng/g)]。在一些海洋中检测到BPF(黄色海蛋白,bigeye,金斑家兔鱼,冷落蓬帕诺,鞋舌鞋底,Bleeker的石斑鱼和橙色斑点石斑鱼)和淡水鱼(mud鱼,鲤鱼,罗非鱼,鲶鱼,普通话鱼,草鱼,灰色鱼和斑点蛇头)。其中两种化合物,BPS和BPB只能在海洋鱼类中识别(蛇头,黄色海蛋白)。在PFAA分析中,PFOA,PFDA,全氟辛烷磺酸,在大多数海洋和淡水鱼中都发现了PFUdA和PFDoA。PFOS和PFOA被证明是鱼类中两种主要的PFAA。根据测得的双酚浓度,BPs(BPA,BPB,BPF,BPS)和PFAA,计算了BP(20.5-31.5ng/kb.w./天)和PFAA(1.17-1.83ng/kb.w./天)的平均每日摄入量,发现低于欧洲规定的可容忍每日摄入量(TDI)。然而,与我们之前2011年的研究相比,本研究显示鱼样中BPA的浓度增加了约10倍.尽管食用鱼类接触BPA和PFAA的危险比预计将保持较低,在人类健康风险评估中,应考虑BPA及其类似物以及PFAA的可能的累加代谢干扰作用。
Our previous study in 2011 reported the detection of BPA and PFAAs in 20 species of marine and freshwater fishes. With an emerging evidence to suggest the metabolic-disrupting effects of BPA/PFAAs in animals, the present study was aimed to provide a time-trend analysis to determine the current concentrations of PFAAs and BPA in 20 commercially available Hong Kong species of fishes. Since the manufacture and use of BPA is being prohibited in most nations, the introduction of BPA alternatives has recently been incorporated in the markets. Therefore, the concentrations of
BPB, BPF and BPS were determined. In the present study, all freshwater and seawater fish samples showed quantified concentrations [>Limit of Quantification (LOQ<0.5ng/g)] of BPA. BPF was detected in some marine (yellow seafin, bigeye, goldspotted rabbitfish, snubnose pompano, tongue sole, Bleeker\'s grouper and orange-spotted grouper) and freshwater fishes (mud carp, crucian carp, tilapia, catfish, mandarin fish, grass carp, grey mullet and spotted snakehead). Two of the compounds, BPS and
BPB could only be identified in the marine fishes (snubnose pompano, yellow seafin). In PFAA analysis, PFOA, PFDA, PFOS, PFUdA and PFDoA were found in most of the marine and freshwater fishes. PFOS and PFOA were shown to be the two predominant PFAAs in fishes. On the basis of the measured concentrations of bisphenols, BPs (BPA,
BPB, BPF, BPS) and PFAAs, the average daily intake for BPs (20.5-31.5ng/kgb.w./day) and PFAAs (1.17-1.83ng/kgb.w./day) were calculated and found to be lower than values of tolerable daily intake (TDI) established in Europe. However, as compared with our previous study in 2011, the present study revealed an approximate 10-fold increase in the concentrations of BPA in the fish samples. Although the hazard ratio of consuming fishes for BPA and PFAA exposure is expected to remain low, possible additive metabolic-disrupting effect of BPA and its analogues as well PFAAs should be taken into consideration for human health risk assessment.