背景:踝臂指数(ABI)是踝部和肱部收缩压的比值。在临床上,低ABI(<0.9)是外周动脉粥样硬化的指标,而高ABI(>1.4)是动脉僵硬和钙化的标志。本研究的目的是调查ABI和体力活动水平之间的关系,由加速度计测量。
方法:瑞典CARdio肺生物图像研究(SCAPIS)是瑞典全国范围内基于人群的横断面队列,用于研究心血管和肺部疾病,其中从普通人群中随机邀请50-64岁的个体。有ABI数据的研究人群,身体活动,基于加速度测量的久坐时间为27,737。ABI类别之间的差异和与久坐行为的关联,中等至剧烈的体力活动(MVPA),和其他代谢特征进行了比较。ABI被归类为低,ABI≤0.9,边界线,ABI0.91-0.99,正常,ABI1.0-1.39,高,ABI≥1.4。
结果:与久坐的四分位数相比,久坐的四分位数中低ABI的患病率更高(0.6%vs.0.1%,p<0.001)。久坐的人也表现出更高的BMI,糖尿病和高血压的患病率较高。与ABI正常的患者相比,在MVPA中花费的唤醒时间比例在ABI低的患者中最低(0.033±0.004;p<0.001),在ABI>1.4的患者中最高(0.069±0.001;p<0.001)。与正常ABI相比,久坐时间的比例在ABI低的人群中最高(0.597±0.012;p<0.001),在ABI>1.4的人群中最低(0.534±0.002;p=0.004)。
结论:这项基于人群的研究表明,ABI>1.4的中年人的体力活动水平最高,而ABI较低的个体,尤其是那些ABI<0.9的人,不那么活跃,花更多的时间久坐。需要进一步的研究来了解ABI之间的关系,身体活动,以及一般人群中外周动脉和心血管疾病的风险。
BACKGROUND: The ankle-brachial index (ABI) is the ratio of the ankle and brachial systolic blood pressures. In the clinical setting, low
ABI (< 0.9) is an indicator of peripheral atherosclerosis, while high
ABI (> 1.4) is a sign of arterial stiffness and calcification. The purpose of the current study was to investigate the association between ABI and physical activity levels, measured by accelerometer.
METHODS: The Swedish CArdioPulmonary bioImage Study (SCAPIS) is a Swedish nationwide population-based cross-sectional cohort for the study of cardiovascular and pulmonary diseases, in which individuals aged 50-64 years were randomly invited from the general population. The study population with data on ABI, physical activity, and sedentary time based on accelerometry was 27,737. Differences between ABI categories and associations to sedentary behavior, moderate to vigorous physical activity (MVPA), and other metabolic characteristics were compared.
ABI was categorized as low,
ABI ≤ 0.9, borderline,
ABI 0.91-0.99, normal,
ABI 1.0-1.39, and high,
ABI ≥ 1.4.
RESULTS: Prevalence of low ABI was higher in the most sedentary quartiles compared to the least sedentary (0.6% vs. 0.1%, p < 0.001). The most sedentary individuals also exhibited higher BMI, higher prevalence of diabetes and hypertension. The proportion of wake time spent in MVPA was lowest in those with low ABI (0.033 ± 0.004; p < 0.001) and highest in those with
ABI > 1.4 (0.069 ± 0.001; p < 0.001) compared to those with normal
ABI. Compared to normal
ABI, the proportion of sedentary time was highest in those with low
ABI (0.597 ± 0.012; p < 0.001) and lowest in those with ABI > 1.4 (0.534 ± 0.002; p = 0.004).
CONCLUSIONS: This population-based study shows that middle-aged individuals with ABI > 1.4 have the highest level of physical activity, while individuals with a lower ABI, especially those with
ABI < 0.9, are less active and spend more time sedentary. Future studies are needed to understand the relationships between ABI, physical activity, and the risk of peripheral arterial and cardiovascular disease in the general population.