截至2022年4月,印度已发现超过4300万例COVID-19确诊病例,治愈率为98.8%,导致很大一部分人口,包括医护人员(HCWs),容易发生COVID后遗症。这项研究旨在评估COVID-19感染后医学后遗症的性质和患病率,和风险因素,如果有的话,与他们有关。方法:这是一个观察性的,在8个三级护理中心进行的多中心横断面研究.同意的参与者是COVID-19感染后出院后12-52周的医护人员。人口统计数据,病史,通过具体问卷收集COVID-19的临床特征和COVID后遗症的各种症状。结果:679名合格参与者的平均年龄为31.49±9.54岁。COVID后遗症的总体患病率为30.34%,疲劳(11.5%)是最常见的,其次是失眠(8.5%),活动期间呼吸困难(6%)和关节疼痛(5%)。在患有中度至重度COVID-19的参与者中,有任何后遗症的几率最高(OR6.51;95%CI3.46-12.23),在男性中更低(OR0.55;95%CI0.39-0.76)。除了这些,其他有后遗症的预测因素是年龄(≥45岁),存在任何合并症(尤其是高血压和哮喘),HCW类别(非医生vs医生)和COVID-19导致的住院。解释:大约三分之一的参与者经历了COVID后遗症。COVID疾病的严重程度,女性性别,高龄,合并症是COVID后遗症的重要危险因素。资助:这项工作是印度医学研究委员会(ICMR)-合理使用药物网络的一部分。没有从ICMR获得额外的财政支持来开展这项工作,对于学习材料,医学写作,和APC。通过其合理使用药物的工作组项目资助印度医学研究理事会(ICMR)。
UNASSIGNED: India has seen more than 43 million confirmed cases of COVID-19 as of April 2022, with a recovery rate of 98.8%, resulting in a large section of the population including the healthcare workers (HCWs), susceptible to develop post COVID sequelae. This study was carried out to assess the nature and prevalence of medical sequelae following COVID-19 infection, and risk factors, if any.
UNASSIGNED: This was an observational, multicenter cross-sectional study conducted at eight tertiary care centers. The consenting participants were HCWs between 12 and 52 weeks post discharge after COVID-19 infection. Data on demographics, medical history, clinical features of COVID-19 and various symptoms of COVID sequelae was collected through specific questionnaire.
UNASSIGNED: Mean age of the 679 eligible participants was 31.49 ± 9.54 years. The overall prevalence of COVID sequelae was 30.34%, with fatigue (11.5%) being the most common followed by insomnia (8.5%), difficulty in breathing during activity (6%) and pain in joints (5%). The odds of having any sequelae were significantly higher among participants who had moderate to severe COVID-19 (OR 6.51; 95% CI 3.46-12.23) and lower among males (OR 0.55; 95% CI 0.39-0.76). Besides these, other predictors for having sequelae were age (≥45 years), presence of any comorbidity (especially hypertension and asthma), category of HCW (non-doctors vs doctors) and hospitalisation due to COVID-19.
UNASSIGNED: Approximately one-third of the participants experienced COVID sequelae. Severity of COVID illness, female gender, advanced age, co-morbidity were significant risk factors for COVID sequelae.
UNASSIGNED: This work is a part of Indian Council for Medical Research (ICMR)- Rational Use of Medicines network. No additional financial support was received from ICMR to carry out the work, for study materials, medical writing, and APC.