juvenile

青少年
  • 文章类型: Journal Article
    这项研究的目的是确定万隆市儿童特别发展研究所的移情训练对少年犯欺凌行为的影响。
    本研究采用了具有准实验设计的定量方法,并与对照组进行前后测试。抽样技术使用目的性抽样,并获得了100名受访者的样本(50个干预组和50个对照组)。共情培训进行了3个月多达4个课程,包括教育,角色扮演,看电影,和反思。数据收集使用了印度尼西亚版本的OlweusBully/受害者调查表。单变量分析使用平均值,min-max,和标准偏差值。双变量分析采用Wilcoxon检验和Mann-Whitney检验。
    结果显示,在干预组中,大多数受访者在干预前的欺凌行为较高(70%),在干预后的欺凌行为较低(64%).在对照组中,大多数受访者在测试前表现出高水平的欺凌行为(80%),在测试后表现出高水平的欺凌行为(78%).Wilcoxon检验结果显示ap值<0.001,表明在接受同理心训练后,对减少LPKA万隆市囚犯的欺凌行为有显著影响。Mann-Whitney检验的结果显示p<0.001的值,这意味着对照组和干预组之间的欺凌行为水平存在差异。
    同理心培训是万隆市儿童特殊发展研究所社区护士实施社区护理干预措施,防止儿童和青少年欺凌的建议,尤其是在监狱里的青少年。
    UNASSIGNED: The purpose of this study was to determine the effect of empathy training on bullying behavior in juvenile prisoners at the Bandung City Special Development Institute for Children.
    UNASSIGNED: This study used a quantitative method with a quasi-experimental design with pre and post-test with control group. The sampling technique used purposive sampling and obtained a sample of 100 respondents (50 intervention group and 50 control group). Empathy training was conducted for 3 months as many as 4 sessions consisting of education, role play, watching movies, and reflection. Data collection used the Indonesian version of the Olweus Bully/Victim Questionnaire. Univariate analysis used mean, min-max, and standard deviation values. Bivariate analysis used Wilcoxon test and Mann-Whitney test.
    UNASSIGNED: The results showed that in the intervention group, most respondents had high bullying behavior before the intervention (70%) and had low bullying behavior after the intervention (64%). In the control group, most respondents showed a high level of bullying behavior (80%) at pre-test and had high level of bullying behavior (78%) at post-test. The results of the Wilcoxon test showed ap value of <0.001, indicating that there was a significant effect on reducing bullying behavior in prisoners in LPKA Bandung City after being given empathy training. The results of the Mann-Whitney test showed a value of p<0.001 which means that there is a difference in the level of bullying behavior between the control and intervention groups.
    UNASSIGNED: Empathy training is a recommendation for community nurses in Bandung City Special Development Institute for Children to implement community-based nursing interventions in preventing bullying in children and adolescents, especially adolescents in prison.
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  • 文章类型: Journal Article
    抹香鲸在成熟时按性别和社会行为在空间上隔离。在北大西洋,雄鲸移动到更高的纬度,直到80°N的斯瓦尔巴群岛,而雌性和幼鲸通常保持在40-45°以下的低纬度地区。亚速尔群岛,马德拉,加那利群岛是雌性和年轻抹香鲸的重要苗圃。爱尔兰水域代表了该物种在东北大西洋的空间隔离的中点,该物种出现在该国西部的海底峡谷系统中。历史上,只有雄鲸被认为是在这个51到55°之间的地区发现的,但1910年,一名成年女性被商业捕鲸者抓获,1916年发现一头5.49米小牛搁浅。在1995年至2023年之间,有10头雌性抹香鲸被困在爱尔兰海岸。自2013年以来,这些鲸鱼中有八只搁浅,在2019年至2023年之间,每年至少有一次搁浅。其中四次搁浅发生在爱尔兰西北部的多尼戈尔,表明该地区大陆架上有雌性鲸鱼。两只雌性在一天之内被困,并在2022年2月被发现处于相似的分解状态,这表明它们可能是同一组的一部分,而不是孤独的流浪个体。2001年,2004年和2010年,在洛克尔槽的爱尔兰水域也发现了抹香鲸的小牛和幼鲸,沿着豪猪银行和GobanSpur,在2004年,有4次观察到1到3个个体,而一头小牛被困。这些记录表明,该地区历史上有雌性和年轻的抹香鲸,但在过去十年中,抹香鲸的数量明显增加。
    Sperm whales spatially segregate by sex and social behavior as they mature. In the North Atlantic, male whales move to higher latitudes as far as Svalbard at 80° N, while females and young whales typically remain around lower latitudes below 40-45° N. The Azores, Madeira, and the Canary Islands constitute important nursery grounds for female and young sperm whales. Irish waters represent a midpoint for this species\' spatial segregation in the Northeast Atlantic, where the species occurs along the submarine canyon systems to the west of the country. Historically, just male whales were thought to be found in this region between 51 and 55° N, but one adult female was caught by commercial whalers in 1910, and a 5.49 m calf was found stranded in 1916. Between 1995 and 2023, 10 female sperm whales have been stranded around the coast of Ireland. Eight of these whales have been stranded since 2013, and there has been at least one stranding per year between 2019 and 2023. Four of these strandings have occurred in Donegal in the northwest of Ireland, indicating the presence of female whales along the continental shelf off this region. Two females were stranded within a day of each other and were found in similar states of decomposition in February 2022, indicating that they may have been part of the same group rather than being lone vagrant individuals. Sperm whale calves and juveniles were also sighted in Irish waters in 2001, 2004, and 2010 in the Rockall Trough, along the Porcupine Bank and Goban Spur, where between 1 and 3 individuals were observed on four occasions while one calf live stranded in 2004. These records indicate a historical presence of female and young sperm whales in this region but that an apparent increase in occurrence has taken place over the past decade.
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  • 文章类型: Journal Article
    目的:耳硬化症是一种相对罕见的疾病,可导致儿童传导性听力损失。成人的首选治疗方法是stapedsometry,而对于18岁以下的人来说,关于最佳治疗方法的讨论正在进行中。因此,儿科患者骨的外科手术仍然是一个争论的话题。这项研究旨在评估儿童stapes骨手术的结果,试图理解,根据我们的结果,这实际上是否是最合适的选择。
    方法:该研究包括2013年1月至2023年12月期间接受手术的18例患者。患者年龄从11岁到18岁不等,平均年龄为14.7岁。在总共21次手术中,3例患者选择双侧手术.术前、术后资料进行比较,重点关注频率为0.5、1、2和4kHz的平均空气传导(AC)和骨传导(BC)阈值。此外,检查术前阈值和术后气骨间隙(ABG).
    结果:一年后,在21例中,94%的病例中,空气-骨间隙有效降低到10dB或更低,在98%的情况下达到20dB或更低。
    结论:我们在该领域的结果和研究一致表明,由熟练的耳外科医生进行时,是一个可靠和成功的程序为相当多的患者。它产生的结果与成年期间通过该程序获得的结果相似。
    OBJECTIVE: Otosclerosis is a relatively uncommon condition that causes conductive hearing loss in children. The preferred treatment for adults is stapedotomy, while for individuals under 18 years old, there is an ongoing discussion about the best treatment approach. Thus, the surgical procedure for the stapes in pediatric patients continues to be a subject of debate. This study aimed to evaluate the results of stapes surgery in children, trying to understand, based on our results, whether this is actually the most suitable option.
    METHODS: The study included 18 patients who underwent surgery between January 2013 and December 2023. The patients\' ages ranged from 11 to 18 years, with an average age of 14.7. Out of the total 21 surgeries, three patients opted for bilateral surgery. Pre- and post-operative data were compared, focusing on the mean air conduction (AC) and bone conduction (BC) thresholds at frequencies of 0.5, 1, 2, and 4 kHz. Additionally, pre-operative thresholds and the post-operative air-bone gap (ABG) were examined.
    RESULTS: After a year, the air-bone gap was effectively reduced to 10 dB or less in 94% of the 21 cases, and to 20 dB or less in 98% of all cases.
    CONCLUSIONS: Our results and research in the field have consistently shown that stapedotomy, when conducted by skilled otosurgeons, is a reliable and successful procedure for a considerable number of patients. The outcomes it generates are similar to those achieved through the procedure conducted during adulthood.
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  • 文章类型: Journal Article
    在许多生物体中,包括鱼类,下游分散通常是表型依赖性的。表型依赖的下游扩散可以通过空间分选产生进化压力,非随机去除表型,增强上游种群的下游扩散。由于下游扩散而导致的空间分类可能会在屏障上方栖息地的鱼类种群中积累,分散的个体无法返回,导致减少下游扩散的功能性状。在较小的屏障上方栖息地中,这种进化机制可能更为重要,在这些栖息地中,下游迁移发生在较短的扩散距离上。这项研究在实验罐中观察了脂肪小鱼Rhynchocyphypechycephalusjouyi幼鱼的扩散行为,以检查来自小型屏障上方栖息地的幼鱼是否比来自大型屏障上方栖息地的幼鱼表现出更有利于减少下游扩散的行为。来自小型屏障上方栖息地的少年比来自大型屏障上方栖息地的少年避免了向下游扩散的持续时间更长,但是上升尝试的频率没有差异。这些结果支持这样的观点,即通过空间分类来改善屏障上方小种群中青少年的行为特征,以减少下游扩散。发现种群间的扩散行为变化仅在某些扩散方向上发生,这表明栖息地碎片化的行为后果比以前的假设更为复杂。
    In many organisms, including fishes, downstream dispersal is often phenotype-dependent. Phenotype-dependent downstream dispersal can generate evolutionary pressure via spatial sorting, which non-randomly removes phenotypes enhancing downstream dispersal from upstream populations. Spatial sorting due to downstream dispersal could accumulate in fish populations in above-barrier habitats to which dispersed individuals cannot return, resulting in functional traits that reduce downstream dispersal. This evolutionary mechanism may be more important in smaller above-barrier habitats where downstream emigration occurs over shorter dispersal distances. This study observed the dispersal behavior of fat minnow Rhynchocypris oxycephalus jouyi juveniles in an experimental tank to examine whether juveniles from small above-barrier habitats show more behaviors favorable for reducing downstream dispersal than those from large above-barrier habitats. Juveniles from small above-barrier habitats avoided downstream dispersal for longer durations than those from large above-barrier habitats, but there was no difference in the frequency of ascending attempts. These results support the notion that behavioral traits of juveniles in small above-barrier populations have been refined by spatial sorting to reduce downstream dispersal. The finding that interpopulation variation in dispersal behavior occurred only for certain dispersal directions implies that the behavioral consequences of habitat fragmentation are more complex than previously assumed.
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  • 文章类型: Journal Article
    年轻的早熟鸟类受益于与母亲和兄弟姐妹保持亲密关系,在优先考虑成年人的同时,提供更好的护理。幼鸟使用刺激的哪些特征来优先考虑方法,并最终对成年而不是兄弟姐妹的依恋尚不清楚。我们开始在新孵化的家养小鸡(Gallusgallus)中解决这个问题,专注于他们对成年鸡和幼鸡之间系统性变化的视觉特征的自发偏好,以前被认为是有吸引力的:尺寸(成年人比青少年更大)和颜色(成年人比青少年更暗,更红)。总的来说,小鸡在他们的第一次视觉体验,以前从未见过特定的,最吸引红色和大刺激(两个成人特征),并且与红色刺激相比,与黄色刺激相比,与红色刺激紧密接触的时间更多。当使用红色大对象与小对象进行测试时(实验。1),小鸡更喜欢大的形状。当使用黄色大物体和小物体进行测试时(实验。2),小鸡没有表现出偏好。小鸡对大的红色刺激有更强的偏好(与小黄色物体)比红色小刺激(vs.黄色大物体)(实验。3).这些结果表明,大小和颜色的结合形成了一种倾向,可以帮助雏鸡从生命的第一阶段自发区分成年和幼年的特征。在没有以前经验的情况下,表现出倾向于接近具有与成人物种存在相关特征的刺激。
    Young precocial birds benefit from staying close to both their mother and their siblings, while prioritising adults, which provide better care. Which features of the stimuli are used by young birds to prioritise approach and eventually attachment to adults over siblings is unknown. We started to address this question in newly hatched domestic chicks (Gallus gallus), focusing on their spontaneous preferences for visual features that systematically vary between adult and juvenile chickens, and that had previously been identified as attractive: size (larger in adults than in juveniles) and colour (darker and redder in adults than in juveniles). Overall, chicks at their first visual experience, that had never seen a conspecific beforehand, were most attracted to the red and large stimuli (two adult features) and spent more time in close proximity with red stimuli than with yellow stimuli. When tested with red large versus small objects (Exp. 1), chicks preferred the large shape. When tested with yellow large and small objects (Exp. 2), chicks did not show a preference. Chicks had a stronger preference for large red stimuli (vs. small yellow objects) than for small red stimuli (vs. a large yellow object) (Exp. 3). These results suggest that the combination of size and colour form the predisposition that helps chicks to spontaneously discriminate between adult and juvenile features from the first stages of life, in the absence of previous experience, exhibiting a preference to approach stimuli with features associated with the presence of adult conspecifics.
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  • 文章类型: Journal Article
    成人皮肌炎(DM)和青少年皮肌炎(JDM)是罕见的自身免疫性疾病,具有特征性皮疹,弱点,和其他系统特征。已经在成人和青少年DM中一致地描述了上调的干扰素信号传导,这使得janus激酶抑制剂(jakinibs)成为具有靶向作用机制的有吸引力的治疗剂。
    本文综述了越来越多的成人和青少年糖尿病患者使用jakinib的文献,包括有关该人群中雅基尼人的特定疾病特征和安全性的报告,以及成人和青少年DM之间的比较。我们使用PubMed进行了文献综述,包括2024年2月1日之前的所有英语出版物以及近期重要风湿病学会议的摘要。
    Jakinibs在成人和青少年DM中都是令人兴奋且有前途的治疗方法。目前在成人和JDM中进行的jakinibs的2期和3期随机安慰剂对照试验将为此类药物的功效提供重要见解,作为对皮肤和肌肉疾病的潜在更机械靶向治疗。事实上,这些结果可能为皮肌炎的治疗模式提供信息,因为皮肌炎甚至可能被视为一线或二线.对于患者和医疗提供者来说,青少年和成人DM治疗领域的未来五年是一个激动人心的时刻。
    UNASSIGNED: Adult dermatomyositis (DM) and juvenile dermatomyositis (JDM) are rare autoimmune diseases with characteristic skin rashes, weakness, and other systemic features. Upregulated interferon signaling has been consistently described in both adult and juvenile DM which makes janus kinase inhibitors (jakinibs) an attractive therapeutic agent that has a targeted mechanism of action.
    UNASSIGNED: Herein is a review of the growing literature of jakinib use in adult and juvenile DM, including reports on specific disease features and safety of jakinibs in this population and a comparison between adult and juvenile DM. We performed a literature review using PubMed including all English-language publications before 1 February 2024 and abstracts from key recent rheumatology conferences.
    UNASSIGNED: Jakinibs are an exciting and promising treatment in both adult and juvenile DM. Current Phase 2 and 3 randomized placebo-controlled trials of jakinibs in both adult and JDM will provide significant insights into the efficacy of this class of medication as a potentially more mechanistically targeted treatment of both skin and muscle disease. In fact, these results will likely inform the treatment paradigm of dermatomyositis in that it may even be considered as first or second line. The next five years in the therapeutic landscape of both juvenile and adult DM is an exciting time for both patients and medical providers.
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  • 文章类型: Journal Article
    在迁徙动物中,从没有经验的青少年到繁殖的成年人的发育期可能是塑造人口迁移模式的关键生命阶段。然而,早期迁移程序的发展仍未得到充分探索。虽然在义务移民中描述了与年龄相关的移民路线和时间变化,大多数对部分移民的个体发育的调查仅集中在移民的年龄依赖性上,这是一种二元策略(移民或居民),很少考虑被归类为“移民”的个人之间的路线和时间差异。为了填补这个空白,我们研究迁徙目的地的个体发育,部分迁徙的红色风筝(Milvusmilvus)种群的路线和时间。使用广泛的GPS跟踪数据集(292个雏鸟和38个成年人,每个人跟踪1-5次迁移),我们研究了九种不同的迁徙特征如何随年龄和繁殖状况而变化,其中许多人在以后的生活中成为居民。随着年龄的增长,个人离开繁殖区的时间较晚,到达繁殖区的时间也较早,导致从第一次到第五次迁徙,在繁殖区的停留时间逐渐延长2个月。个人在获得领土的前一年推迟了向南迁移,他们在占领领土后进一步拖延了。随着年龄的增长,迁移路线变得更加直接。个人对他们的越冬地点非常忠诚。随着年龄的增长,迁移距离仅略有缩短,兄弟姐妹之间的迁移距离比无关个体之间的迁移距离更相似。向北和向南迁移的大量逐渐变化表明,在发育窗口期间,时间特征具有高度的可塑性。然而,较高的越冬地点保真度表明了地点熟悉度的巨大好处,促使空间迁移可塑性通过转换为居住区来表达。时空迁移特征之间与年龄相关的变化轨迹的对比模式可能反映了可塑性表达的不同机制。在整个迁徙策略范围内研究物种之间的这种模式,将能够进一步了解迁徙物种对快速环境变化表现出的可塑性反应。
    In migratory animals, the developmental period from inexperienced juveniles to breeding adults could be a key life stage in shaping population migration patterns. Nevertheless, the development of migration routines in early life remains underexplored. While age-related changes in migration routes and timing have been described in obligate migrants, most investigations into the ontogeny of partial migrants only focused on age-dependency of migration as a binary tactic (migrant or resident), and variations in routes and timing among individuals classified as \'migrants\' is rarely considered. To fill this gap, we study the ontogeny of migration destination, route and timing in a partially migratory red kite (Milvus milvus) population. Using an extensive GPS-tracking dataset (292 fledglings and 38 adults, with 1-5 migrations tracked per individual), we studied how nine different migration characteristics changed with age and breeding status in migrant individuals, many of which become resident later in life. Individuals departed later from and arrived earlier at the breeding areas as they aged, resulting in a gradual prolongation of stay in the breeding area by 2 months from the first to the fifth migration. Individuals delayed southward migration in the year prior to territory acquirement, and they further delayed it after occupying a territory. Migration routes became more direct with age. Individuals were highly faithful to their wintering site. Migration distance shortened only slightly with age and was more similar among siblings than among unrelated individuals. The large gradual changes in northward and southward migrations suggest a high degree of plasticity in temporal characteristics during the developmental window. However, the high wintering site fidelity points towards large benefits of site familiarity, prompting spatial migratory plasticity to be expressed through a switch to residency. The contrasting patterns of trajectories of age-related changes between spatial and temporal migration characteristics might reflect different mechanisms underlying the expression of plasticity. Investigating such patterns among species along the entire spectrum of migration tactics would enable further understanding of the plastic responses exhibited by migratory species to rapid environmental changes.
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  • 文章类型: Case Reports
    儿童中最常见的良性喉肿瘤是乳头状瘤。喉乳头状瘤病是一种慢性疾病,在儿童中很少见。我们报告了一个四岁的马来女孩,她患有慢性喉乳头状瘤病,最有可能在分娩过程中垂直获得,被检测到。她三年来一直声音嘶哑,柔性喉镜检查显示声门区乳头状瘤的特征。患者接受了直接喉镜检查,然后使用冷仪器切除肿块。手术干预是喉乳头状瘤病的主要治疗方式,以维持气道通畅和语音质量。
    The most common benign laryngeal neoplasm in children is a papilloma. Laryngeal papillomatosis is a chronic disease and is rare in children. We report the case of a four-year-old Malay girl in whom chronic laryngeal papillomatosis, most likely acquired vertically during labor, was detected. She presented with hoarseness of voice for three years, and a flexible laryngoscopy examination revealed features of papilloma in the glottis area. The patient underwent direct laryngoscopy followed by excision of mass using the cold instrument. Surgical intervention is the primary treatment modality for laryngeal papillomatosis to maintain airway patency and voice quality.
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  • 文章类型: Journal Article
    本研究评估了深色肌肉中镉(Cd)水平和Cd的时间变化,白色肌肉,和幼年Thunnusalbacares的肝脏。在2021年4月至2022年5月期间,从斯里兰卡周围的印度洋水域收集了72个人(标准长度:50-67厘米;体重:0.8-2.5千克)。使用电感耦合等离子体质谱仪分析总Cd水平。不同组织中的平均Cd水平(平均值±SDmgkg-1干重)在肝脏中的水平显着升高(13.62±0.98,p<0.05),与深色肌肉相比(0.52±0.05),白肌(0.42±0.04)。肝脏组织中Cd含量与鱼体重呈正相关(p<0.05)。在深色肌肉中报告的Cd水平,白色的肌肉,在第二次季风期间,肝脏组织显着高于其他季风制度(p<0.05),并且超过了欧盟(EU)设定的最大允许水平(0.1mgkg-1湿重)。然而,测得的白色和深色肌肉中的Cd水平低于粮农组织/世界卫生组织设定的最大允许水平(0.2mgkg-1湿重)。所有肝脏组织中的Cd水平均高于欧盟和FAO/WHO设定的水平。因此,人们应该避免食用来自印度洋的T.albacares的肝脏组织。体重为60公斤的人每周可以消耗高达4.667公斤的白色肌肉,而不会超过临时耐受每周摄入量。
    The present study evaluated the cadmium (Cd) levels and temporal variation of Cd in dark muscle, white muscle, and liver of juvenile Thunnus albacares. 72 individuals (Standard length: 50-67 cm; weight: 0.8-2.5 kg) were collected from Indian Oceanic water around Sri Lanka during the period between April 2021 to May 2022. Total Cd levels were analyzed using an Inductively Coupled Plasma Mass Spectrophotometer. The mean Cd levels (mean ± SD mg kg-1 dry weight) in different tissues varied with significantly higher levels in the liver (13.62 ± 0.98, p < 0.05), compared to dark muscle (0.52 ± 0.05), and white muscle (0.42 ± 0.04). Cd levels in liver tissues were positively correlated (p < 0.05) with the fish weight. The Cd levels reported in dark muscles, white muscles, and liver tissues were significantly higher (p < 0.05) during 2nd inter-monsoon than in the other monsoonal regimes and exceeded the maximum permissible level (0.1 mg kg-1 wet weight) set by the European Union (EU). However, the measured Cd levels in white and dark muscles were below the maximum permissible level (0.2 mg kg-1 wet weight) set by FAO/WHO. The Cd levels in all the liver tissues were above the levels set by the EU and FAO/WHO. Accordingly, people should avoid the consumption of liver tissues of T. albacares from the Indian Ocean. A human with a body weight of 60 kg can consume white muscles up to 4.667 kg per week without exceeding the Provisional Tolerable Weekly Intake.
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  • 文章类型: Case Reports
    毛霉和根霉被认为是毛霉菌病的主要罪魁祸首,以其机会性而闻名的严重真菌感染。这种感染主要针对免疫系统受损的个体,包括糖尿病患者和接受糖皮质激素治疗的患者,免疫反应减弱的地方。本文旨在强调及时诊断和强化治疗在控制毛霉菌病中的关键作用。特别是在儿科患者中,因为它可以避免死亡和减轻严重的发病率。该病例报告强调了早期识别糖尿病患者的真菌感染并随后积极治疗以防止不良结局的紧迫性。当及时诊断毛霉菌病并通过强化治疗进行管理时,它强调了出色治疗结果的潜力。通过这样做,可以有效预防与这种情况相关的显著发病率和死亡率,强调对有真菌感染易感因素的患者保持警惕和积极管理的重要性。
    Mucor and Rhizopus species are recognized as the primary culprits responsible for mucormycosis, a severe fungal infection known for its opportunistic nature. This infection primarily targets individuals with compromised immune systems, including those with diabetes mellitus and patients undergoing glucocorticoid therapy, where the immune response is weakened. This article aims to underscore the pivotal role of prompt diagnosis and intensive treatment in managing mucormycosis, particularly in pediatric patients, as it can avert death and mitigate serious morbidity. This case report emphasizes the urgency of identifying fungal infections in patients with diabetes early on and subsequently treating them aggressively to prevent adverse outcomes. It highlights the potential for excellent treatment outcomes when mucormycosis is promptly diagnosed and managed with intensive therapy. By doing so, significant morbidity and mortality associated with this condition can be effectively prevented, underscoring the importance of vigilance and proactive management in patients with predisposing factors for fungal infections.
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