external fixation

外固定
  • 文章类型: Journal Article
    对于桡骨远端骨折(DRF),有许多内固定(IF)选项。固定方法的选择取决于骨折形态等因素,软组织完整性,患者的临床状况,和外科医生的训练。虽然掌侧钢板固定已成为解决这些骨折的主要方法,替代IF方法,如K线固定,碎片特异性固定,和背桥电镀继续有效。尽管IF的多功能性,在某些临床情况下,不适合通过切开复位内固定术(ORIF)进行及时和决定性的治疗.这些例子包括多发性创伤患者的治疗,软组织受损的个体,或那些在医学上不稳定以耐受长时间麻醉的人。在这种情况下,熟练的闭合复位和外固定(EF)证明是非常宝贵的。能够识别这些临床情况并理解EF在解决DRF方面的功效和安全性对于处理此类损伤的任何外科医生都是有价值的。
    There are numerous internal fixation (IF) options available for distal radius fractures (DRFs). The choice of fixation method depends on factors such as fracture morphology, soft tissue integrity, the patient\'s clinical status, and the surgeon\'s training. While volar plate fixation has become the primary approach for addressing these fractures, alternative IF methods like K-wire fixation, fragment-specific fixation, and dorsal bridge plating continue to be effective. Despite the versatility of IF, there are certain clinical situations where prompt and conclusive management through open reduction and internal fixation (ORIF) is not suitable. These instances include the treatment of polytraumatized patients, individuals with compromised soft tissues, or those medically unstable to tolerate lengthy anesthesia. In such cases, proficiency in closed reduction and external fixation (EF) proves invaluable. Being able to identify these clinical scenarios and comprehend the efficacy and safety of EF in addressing DRFs is valuable for any surgeon handling such injuries.
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  • 文章类型: Journal Article
    目的:儿童患者股骨干长度不稳定型骨折(LUFSF)的治疗仍存在争议。本研究旨在探讨超声引导下闭合复位结合外固定架治疗儿童LUFSF的临床疗效。
    方法:我们对2018年1月至2023年1月期间接受超声引导下闭合复位和外固定的19例LUFSF儿科患者的临床数据进行了回顾性分析。超声不仅用于促进骨折的闭合复位,而且还用于引导Schanz引脚的实时插入并监测引脚穿过相对皮质的长度。手术时间,术中透视计数,住院时间,骨折固定持续时间,并发症发生率,记录最终随访时的骨折复位质量.
    结果:患者的平均年龄为7.5岁(范围:5至11岁)。平均手术时间为70.4分钟(范围:48-105分钟),术中透视平均计数为6.5(范围:2-16)。骨折固定术7~20周,平均10.9周。所有患者均随访一年以上。6例发生浅表针道感染,通过口服抗生素和加强针道护理解决。未观察到深部感染。在2例患者中观察到膝关节暂时僵硬。根据Flynn的疗效评估系统,最终随访时骨折复位质量优良11例,满意8例,综合成功率为100%(19/19)。
    结论:超声引导下闭合复位结合外固定的技术为5至11岁的LUFSF儿童提供了良好的结果,减少对透视引导的依赖。
    OBJECTIVE: The management of length-unstable femoral shaft fractures(LUFSFs) in pediatric patients is still controversial. This study aims to explore the clinical efficacy of ultrasound-guided closed reduction combined with external fixation for treating LUFSFs in children.
    METHODS: We conducted a retrospective analysis of clinical data from 19 pediatric patients with LUFSFs who underwent ultrasound-guided closed reduction and external fixation between January 2018 and January 2023. Ultrasound was employed not only to facilitate closed reduction of the fracture but also to guide real-time insertion of Schanz pins and monitor pin length as it traversed the opposite cortex. Surgical time, intraoperative fluoroscopy count, hospital stay length, fracture fixation duration, complication incidence, fracture reduction quality at the final follow-up were recorded.
    RESULTS: The patients\' average age was 7.5 years( range: 5 to 11 years). The mean surgical duration was 70.4 min (range: 48-105 min), and the average intraoperative fluoroscopy count was 6.5 (range: 2-16). Fracture fixation lasted an average of 10.9 weeks (range: 7-20 weeks). All patients were followed up for more than one year. 6 cases of superficial pin tract infection occurred, which resolved with oral antibiotics and enhanced needle tract care. No deep infections were observed. Temporary stiffness of the knee joint was observed in 2 patients. According to Flynn\'s efficacy evaluation system, fracture reduction quality at the final follow-up was rated as excellent in 11 cases and satisfactory in 8 cases, yielding a combined success rate of 100% (19/19).
    CONCLUSIONS: The technique of ultrasound-guided closed reduction combined with external fixation offers favorable outcomes for children aged 5 to 11 years with LUFSFs, reducing reliance on fluoroscopic guidance.
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  • 文章类型: Journal Article
    目的:对于严重的下颌骨骨折,快速成型和组装现代外固定器仍然是一个挑战,尤其是在紧急情况下。我们设计了一种新型的外固定器,该固定器结合了万向节,可为下颌骨粉碎性骨折提供稳定。本研究旨在通过体外生物力学测试和动物实验证实这种新型外固定器的功效。
    方法:使用6只具有下颌骨缺损的新鲜犬进行体外生物力学测试,以模拟严重的粉碎性骨折。用新型外固定器稳定三个下颌骨,用2.5mm重建板固定其他下颌骨。所有固定的下颌骨在牙齿的前部区域承受350N的载荷,在未受影响的一侧的第一磨牙承受550N的载荷。根据最大位移和载荷-位移曲线的斜率评估稳定性。在动物实验中,将9只患有下颌骨粉碎性骨折的比格犬分为3组,用新型外固定架治疗,重建板,和牙弓棒,分别。一般的观察,动物体重的变化,记录并比较3组的手术时间。以0天的不同间隔(手术后立即)进行CT扫描,3天,7天,14天,21天,和28天分析犬下颌骨特征点的位移和28天骨折愈合情况。通过方差分析和Bonferroni检验的双向分析来评估统计学意义。使用GraphPadPrism10.1.0(GraphPadInc,美国)。
    结果:生物力学测试结果表明,外固定组和内固定组之间在两种载荷模式下的最大位移(p=0.496,0.079)和载荷位移曲线斜率(p=0.374,0.349)方面没有统计学上的显着差异。动物实验数据显示,外固定组和内固定组之间的特征点存在微小位移,无统计学差异。而足弓杆组的稳定性较差。CT分析显示内固定组骨折愈合最好,然后在固定后28天进行外固定和牙弓裸露。外固定组固定时间(25.67±3.79)min短于内固定(70.67±4.51)min,p<0.001)和足弓裸露((42.00±3.00)min,p=0.046)。
    结论:本研究的结论强调了这种新型外固定器快速治疗下颌骨骨折的有效性和可靠性,在紧急救援的背景下,为下颌骨粉碎性骨折的初步稳定提供了一个可行的选择。
    OBJECTIVE: Shaping and assembling contemporary external fixators rapidly for the severe mandibular fractures remains a challenge, especially in emergency circumstance. We designed a novel external fixator that incorporates universal joints to provide the stabilization for mandibular comminuted fractures. This study aims to confirm the efficacy of this novel external fixator through biomechanical tests in vitro and animal experiments.
    METHODS: In vitro biomechanical tests were conducted using 6 fresh canine with mandibular defect to simulate critical comminuted fractures. Three mandibles were stabilized by the novel external fixator and other mandibles were fixed by 2.5 mm reconstruction plates. All fixed mandibles were subjected to loads of 350 N on the anterior regions of teeth and 550 N on the first molar of the unaffected side. The stability was evaluated based on the maximum displacement and the slope of the load-displacement curve. In animal experiments, 9 beagles with comminuted mandibular fractures were divided into 3 groups, which were treated with novel external fixation, reconstruction plate, and dental arch bar, respectively. The general observation, the changes in animals\' weight, and the surgical duration were recorded and compared among 3 groups. The CT scans were performed at various intervals of 0 day (immediately after the surgery), 3 days, 7 days, 14 days, 21 days, and 28 days to analyze the displacement of feature points on the canine mandible and situation of fracture healing at 28 days. The statistical significance was assessed by the two-way analysis of variance test followed by the Bonferroni test, enabling multiple comparisons for all tests using GraphPad Prism10.1.0 (GraphPad Inc, USA).
    RESULTS: The outcomes of the biomechanical tests indicated that no statistically significant differences were found in terms of the maximum displacement (p = 0.496, 0.079) and the slope of load displacement curves (p = 0.374, 0.349) under 2 load modes between the external and internal fixation groups. The animal experiment data showed that there were minor displacements of feature points between the external and internal fixation groups without statistic difference, while the arch bar group demonstrated inferior stability. The CT analysis revealed that the best fracture healing happened in the internal fixation group, followed by the external fixation and arch baring at 28 days after fixation. The external fixation group had the shortest fixation duration (25.67 ± 3.79) min compared to internal fixation ((70.67 ± 4.51) min, p < 0.001) and arch baring ((42.00 ± 3.00) min, p = 0.046).
    CONCLUSIONS: The conclusion of this study highlighted the efficacy and reliability of this novel external fixator in managing mandibular fractures rapidly, offering a viable option for the initial stabilization of comminuted mandibular fractures in the setting of emergency rescue.
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  • 文章类型: Journal Article
    背景:开放性胫骨干骨折的治疗选择包括有或没有早期内固定转换的外固定。
    目的:这项研究的目的是描述1)早期转换为内固定和确定性外固定,以及2)在转换的情况下,确定并发症的危险因素。
    方法:胫骨干开放性骨折的72个外部固定(Gustilo分类,7处(9.7%)Ⅰ级骨折,二级骨折25处(34.7%),一项连续非随机研究包括40例(55.6%)III级骨折(31例IIIA级和9例IIIB级)。在平均40.5+/-15天的时间内,将33例没有感染迹象的骨折转换为内固定(IF组)。其余39例骨折(EF组)均维持外固定。
    结果:在\"IF\"组中,在6.3+/-3.6个月(3-16)时,愈合率为69.7%。所有患者在16个月时完全愈合,需要2.8+/-0.8重新操作。仅使用外固定架固定(“EF”组)的愈合率在8.9/-4(5-22)个月时为51.3%,在3.7/-0.9再次手术后16个月时为96%。发现浅表感染(12.1%;p=0.011)和大量手术(2.76;p=0.004)是深部感染的危险因素。伤口闭合时间>7天(p=0.049),再手术时间>28天(p=0.00),大量手术(2.76;p=0.004)和深部感染(6.1%;p=0.027)被发现是工会失败的因素。
    结论:早期外固定支架转换为内固定支架是选定的胫骨开放性骨折患者实现骨愈合的有效选择。
    BACKGROUND: Treatment options for open tibial shaft fractures include external fixation with or without early conversion to internal fixation.
    OBJECTIVE: The aim of this study was to describe 1) early conversion to internal fixation and definitive external fixation and 2) in case of conversion, to identify risk factors for complications.
    METHODS: Seventy-two external fixations of open fractures of the tibial shaft (Gustilo classification, 7 fractures (9.7 %) grade I, 25 fractures (34.7 %) grade II, 40 fractures (55.6 %) grade III (31 grade IIIA and 9 grade IIIB)) were included in a continuous non-randomised study. Thirty-three fractures without infection signs were converted to internal fixation at a mean time of 40.5 +/-15 days (IF group). External fixation was maintened in the remaining 39 fractures (EF group).
    RESULTS: In the \"IF\" group, the union rate was 69.7 % at 6.3 +/-3.6 months (3-16). All patients had complete union at 16 months, requiring 2.8 +/-0.8 reoperations. Fixation with external fixation only (\"EF\" group) showed a union rate of 51.3 % at 8.9 +/-4 (5-22) months and 96 % at 16 months after 3.7 +/-0.9 reoperations. Superficial infection (12.1 %; p = 0.011) and numerous surgeries (2.76; p = 0.004) were found to be risk factors for deep infection. Time to wound closure >7 days (p = 0.049), time to reoperation >28 days (p = 0.00), numerous surgeries (2.76; p = 0.004) and deep infection (6.1 %; p = 0.027) were found to be union failure factors.
    CONCLUSIONS: Early conversion of external fixation to internal fixation is an effective option to achieve bone union of open tibial fractures in selected patients.
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  • 文章类型: Journal Article
    背景:本研究旨在介绍使用双外固定器(无桥接骨固定钉框架和常规腕部桥接外固定器)经皮治疗AO类型C1,C2和C3型桡骨远端骨折的潜在替代方法。
    方法:2018年1月至2021年1月,采用双外固定器治疗52例桡骨远端骨折患者。为了比较,61例患者(61例桡骨远端骨折)用钢板和螺钉系统治疗。使用Mayo手腕评分评估手腕功能。使用患者满意度短期评估来评估患者满意度。P<0.05被认为具有统计学意义。
    结果:所有患者均实现骨折愈合。在29个月的最终随访中(范围,24-34个月)vs36个月(范围,26-39个月)(P>0.05),双外固定器和钢板螺钉系统治疗的患者平均尺骨偏差为31°vs29°(P<0.05),平均Mayo腕部评分为91.12±5.98vs88.12±7.54(P<0.05),患者满意度平均得分为23.42±2.47和23.04±2.32(P>0.05)。
    结论:AO型C1、C2和C3型桡骨远端骨折可以使用双外固定器成功治疗。该技术是除了常规治疗之外的潜在替代方案。
    方法:IIa级。
    BACKGROUND: This study aimed to introduce a potential alternative percutaneous treatment for AO types C1, C2, and C3 distal radius fractures using dual-external fixator (a no-bridging cemented-pin frame and a conventional wrist-bridging external fixator).
    METHODS: From January 2018 to January 2021, 52 patients (52 distal radius fractures) were treated with dual-external fixator. For comparison, 61 patients (61 distal radius fractures) were treated with a plate and screw system. Wrist function was assessed using the Mayo Wrist Score. Patient satisfaction was assessed using the Short Assessment of Patient Satisfaction. A P < 0.05 was considered statistically significant.
    RESULTS: Fracture healing was achieved in all patients. At the final follow-up of 29 months (range, 24-34 months) vs 36 months (range, 26-39 months) (P > 0.05), the patients treated with dual-external fixator and a plate and screw system achieved mean ulnar deviations of 31° vs 29° (P < 0.05), mean Mayo Wrist Scores of 91.12 ± 5.98 vs 88.12 ± 7.54 (P < 0.05), and mean patient satisfaction scores of 23.42 ± 2.47 vs 23.04 ± 2.32 (P > 0.05).
    CONCLUSIONS: AO types C1, C2, and C3 distal radius fractures can be treated successfully using dual-external fixator. The technique is a potential alternative in addition to the conventional treatments.
    METHODS: Level IIa.
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  • 文章类型: Case Reports
    牵张成骨技术的风险之一是血管并发症的发展,例如与所进行的截骨术相关的假性动脉瘤或手术中使用的外部固定器的固定元件。假性动脉瘤是在动脉外膜损伤时形成的,导致逐渐和持续的血液外渗到被封装并连接到动脉腔的周围组织中。本报告描述了一例罕见的胫骨前动脉晚期假性动脉瘤,这是由于胫骨延长手术所致,目的是解决一名57岁女性的腿部长度差异,该女性患有长期控制不良导致的严重周围神经病变糖尿病。我们描述了诊断过程,治疗方案,并确认骨痂的形状如何成为这种病理的可靠指标,正如文献中已经描述的那样。
    One of the risks of distraction osteogenesis-based techniques is the development of vascular complications, such as pseudoaneurysms associated with the osteotomies performed or the fixation elements of the external fixator used in the procedure. Pseudoaneurysm are formed when the tunica adventitia of the artery is injured, resulting in a gradual and persistent blood extravasation into the surrounding tissues that is encapsulated and connected to the arterial lumen. This report describes a rare case of a late-presentation pseudoaneurysm in the anterior tibial artery resulting from a tibial lengthening procedure aimed at addressing a leg length discrepancy in a 57-year-old female with severe peripheral neuropathy resulting from long-standing poorly controlled diabetes mellitus. We describe the diagnostic process, the treatment options and confirm how the shape of the bony callus can be a reliable indicator of this pathology, as has already been described in the literature.
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  • 文章类型: Journal Article
    目的:本研究旨在比较SchatzkerIV-VI型TPFs患者即刻(随后使用闭合切口负压治疗)与延迟ORIF的结局。
    方法:对2018年1月至2019年12月接受ORIF的患者进行了一项前瞻性研究。纳入标准是闭合性骨折患者(>18岁)在受伤后24小时内被送往急诊室(ER)。所有患者均行术前影像评估。两位资深骨科创伤外科医生通过5P的骨筋膜室综合征评估ER的软组织状况,判断最终ORIF的运行时间。第1组(n=16)接受延迟ORIF。第2组(n=16)立即接受ORIF和ciNPT使用。患者在术后2周和6周以及术后3、6和12个月进行随访。评估包括确定固定的时间,住院时间,骨头愈合的时间,手术部位并发症,并在12个月内再次手术。使用通用测角仪测量术后3m,6米,和12米ROM。
    结果:两组患者的人口统计学相似(p>0.05)。第2组显示明确固定的时间明显较短(5.94±2.02vs.0.61±0.28,p<0.0001)和住院时间(14.90±8/78vs.10.30±6.78,p=0.0016)。骨愈合时间没有观察到显著差异,手术部位并发症发生率,再次手术率(p>0.05)。术后第2、3、6和12个月,屈伸膝关节ROM显著改善(p<0.0001)。
    结论:在这项研究中,早期使用ORIF和ciNPT导致住院时间缩短,缩短了膝盖早期主动运动的时间,和改善膝盖ROM。这些结果表明,早期ORIF与ciNPT用于SchatzkerIV-VI型TPFs在某些患者中是安全有效的。然而,需要进一步的研究来证实这些发现在更大和更多样化的人群中.
    OBJECTIVE: This study aims to compare the outcomes of immediate (followed by closed-incision negative-pressure therapy use) versus delayed ORIF in patients with Schatzker type IV-VI TPFs.
    METHODS: A prospective study of patients undergoing ORIF between January 2018 and December 2019 was performed. The inclusion criteria were patients (>18 years) with a closed fracture sent to the emergency room (ER) within 24 h of injury. All the patients underwent preoperative image evaluation. Two senior orthopedic trauma surgeons evaluated the soft tissue condition in the ER by 5P\'s of the compartment syndrome, judging the timing of the operation of definitive ORIF. Group 1 (n = 16) received delayed ORIF. Group 2 (n = 16) received immediate ORIF and ciNPT use. Patient follow-up occurred after 2 and 6 weeks and 3, 6, and 12 months after surgery. The assessments included the time to definitive fixation, the length of hospital stay, the time to bone union, surgical site complications, and reoperation within 12 months. A universal goniometer was used to measure the postoperative 3 m, 6 m, and 12 m ROM.
    RESULTS: The patient demographics were similar between the groups (p > 0.05). Group 2 displayed significantly a shorter time to definitive fixation (5.94 ± 2.02 vs. 0.61 ± 0.28, p < 0.0001) and hospital stay (14.90 ± 8/78 vs. 10.30 ± 6.78, p = 0.0016). No significant difference was observed in the time to bone union, surgical site complication incidence, and reoperation rates (p > 0.05). Flexion and flexion-extension knee ROM were demonstrated to be significantly improved in Group 2, 3, 6, and 12 months postoperatively (p < 0.0001).
    CONCLUSIONS: In this study, early ORIF and ciNPT use resulted in a shorter hospital length of stay, a reduced time to early active motion of the knee, and improved knee ROM. These results suggest that early ORIF with ciNPT for Schatzker type IV-VI TPFs is safe and effective in some patients. However, further research to confirm these findings across larger and more diverse populations is needed.
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    文章类型: Journal Article
    在确定的髓钉(MN)之前使用临时钢板固定(TPF)或外固定(前固定)暂时稳定高能量胫骨骨折是骨科损伤控制中常见的策略。这些方法之间缺乏评估结果的综合数据。这项研究比较了使用TPF或ex-fix稳定的患者的结果,只有早期确定的MN,评估并发症,包括骨不连和深部感染。
    对2014年至2022年在单个一级创伤中心接受MN治疗直至骨折愈合(≥3个月)的成人胫骨骨折患者进行了回顾性研究。评估不愈合和深部感染的医疗记录。人口统计,损伤特征,并记录固定方法。使用Pearson精确检验,将接受TPF和ex-fix的患者与匹配的早期MN队列进行比较,独立t检验,和单向方差分析,取决于适当的变量。
    81例患者被纳入其中;27例患者被TPF(n=12)或ex-fix(n=15)临时处理。54例早期MN病例定义了匹配的队列。所有组均具有相似的患者和骨折特征。两组之间的不愈合率差异显著,使用TPF,前修复,和早期MN组分别为17%,40%和11%(p=0.027)。早期MN的不愈合率较低(11%与40%,p=0.017)和深部感染(13%vs.40%,p=0.028)与前修正相比。
    临时修复后分期MN与较高的骨不连和深部感染率相关。TPF和早期确定的MN之间的并发症发生率没有差异。这些数据表明,在可能的情况下,应避免胫骨骨折的MN固定后再进行MN固定,以支持早期确定的MN。如果需要时间化,TPF可能是比ex-fix更好的选择。证据等级:IV。
    UNASSIGNED: Provisional stabilization of high-energy tibia fractures using temporary plate fixation (TPF) or external fixation (ex-fix) prior to definitive medullary nailing (MN) is a strategy common in damage control orthopaedics. There is a lack of comprehensive data evaluating outcomes between these methods. This study compares outcomes of patients stabilized with either TPF or ex-fix, and with early definitive MN only, assessing complications including nonunion and deep infection.
    UNASSIGNED: A retrospective review was performed on adult patients with tibia fractures treated with MN followed until fracture union (≥3 months) at a single level-1 trauma center from 2014 to 2022. Medical records were evaluated for nonunion and deep infection. Demographics, injury characteristics, and fixation methods were recorded. Significance between patients who underwent TPF and ex-fix was compared with a matched cohort of early MN using Pearson\'s exact tests, independent t-tests, and one-way ANOVA, depending on the appropriate variable.
    UNASSIGNED: 81 patients were included; 27 were temporized with TPF (n = 12) or ex-fix (n = 15). 54 early MN cases defined the matched cohort. All groups had similar patient and fracture characteristics. The difference in rates of nonunion between groups was significant, with TPF, ex-fix, and early MN groups at 17, 40, and 11% respectively (p = 0.027). Early MN had lower rates of nonunion (11% vs. 40%, p = 0.017) and deep infection (13% vs. 40%, p = 0.028) compared to ex-fix.
    UNASSIGNED: Temporary ex-fix followed by staged MN was associated with higher rates of nonunion and deep infection. There was no difference in complication rates between TPF and early definitive MN. These data suggest that ex-fix followed by MN of tibia fractures should be avoided in favor of early definitive MN when possible. If temporization is needed, TPF may be a better option than ex-fix. Level of Evidence: IV.
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  • 文章类型: Journal Article
    背景:在临床实践中,Ilizarov骨运输技术被广泛认为是治疗大段骨缺损的有效方法。然而,轴偏移是胫骨大段骨缺损治疗中常见的并发症,会严重影响骨转运的临床疗效。我们的研究旨在构建和验证用于预测胫骨骨运输轴向偏差的列线图。
    方法:本研究回顾性收集了363例接受胫骨Ilizarov技术骨运输的患者的数据。进行单因素和多因素logistic回归分析以确定轴向偏离的独立危险因素。后来被用来构造列线图。使用决策曲线分析(DCA)评估列线图,校正曲线,和受试者工作特征曲线下面积(AUC)。
    结果:在363例接受Ilizarov胫骨骨运输的患者中,31.7%(115/363)出现轴向偏差。多因素logistic回归分析显示,性别,高度,缺陷部位,外固定架指数是轴位偏离的重要危险因素。列线图模型的AUC值为0.705。校准曲线和决策曲线分析显示实际轴向偏差与预测概率之间具有良好的一致性。
    结论:模型为每个变量分配定量风险评分,可用于预测胫骨骨运输过程中轴向偏离的风险。
    BACKGROUND: The Ilizarov bone transport technique is widely recognised as an effective method for treating large segment bone defects in clinical practice. However, axial deviation is a common complication in the treatment of tibial large segment bone defects, which can have a serious impact on the clinical efficacy of bone transport. Our study aims to construct and validate a nomogram for predicting axial deviation of tibial bone transport.
    METHODS: This study retrospectively collected data from 363 patients who underwent the tibial Ilizarov technique for bone transport. Univariate and multivariate logistic regression analyses were performed to determine the independent risk factors for axial deviation, which were later used to construct a nomogram. The nomogram was evaluated using the decision curve analysis (DCA), the calibration curve, and the area under the receiver operating characteristic curve (AUC).
    RESULTS: Of the 363 patients who underwent Ilizarov tibial bone transport, 31.7% (115/363) experienced axial deviation. Multivariate logistic regression analysis showed that gender, height, defect site, and external fixation index were important risk factors for axial deviation. The AUC value of the nomogram model was 0.705. The calibration curve and the decision curve analysis showed a good consistency between the actual axial deviation and the predicted probability.
    CONCLUSIONS: The model assigns a quantitative risk score to each variable, which can be used to predict the risk of axial deviation during tibial bone transport.
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  • 文章类型: Journal Article
    背景:在临床研究中,尚未评估涂有成纤维细胞生长因子(FGF)-磷酸钙(CP)复合层的钛(Ti)针中骨-针界面强度受损的风险。这项回顾性研究使用Weibull图分析来评估涂有FGF-CP层的Ti针中用于桡骨远端骨折外固定的骨-针界面强度。方法:采用外固定支架治疗桡骨远端骨折。FGF-CP组包括5名患者(所有女性,年龄70.4±5.9(范围:62-77岁),无涂层针组包括10名患者(8名女性和2名男性,年龄64.4±11.7(范围:43-83)岁)。在六周后移除销。测量插入和提取峰值扭矩。使用Weibull图分析评估提取峰值扭矩。结果:我们使用Weibull图分析比较了两组在506Nmm以下的提取扭矩,以进行比较。对于FGF-CP和未涂覆的pin组,Weibull图都是线性的。FGF-CP组(1.7343)的回归线斜率明显高于未涂覆针组(1.5670)(p=0.011)。FGF-CP组(-9.847)的回归线的截距显著低于未涂覆针组(-8.708)(p=0.002)。因此,两条回归线明显不同。结论:涂有FGF-CP层的Ti针在桡骨远端骨折的外固定中具有降低骨-针界面强度受损的风险的潜力。
    Background: The risk of impaired bone-pin interface strength in titanium (Ti) pins coated with fibroblast growth factor (FGF)-calcium phosphate (CP) composite layers is yet to be evaluated in a clinical study. This retrospective study used Weibull plot analysis to evaluate bone-pin interface strength in Ti pins coated with FGF-CP layers for external distal radius fracture fixation. Methods: The distal radial fractures were treated with external fixation. The FGF-CP group comprised five patients (all women, aged 70.4 ± 5.9 (range: 62-77) years), and the uncoated pin group comprised ten patients (eight women and two men, aged 64.4 ± 11.7 (range: 43-83) years). The pins were removed after six weeks. The insertion and extraction peak torques were measured. The extraction peak torque was evaluated using Weibull plot analysis. Results: We compared the extraction torque of the two groups at or below 506 Nmm for a fair comparison using Weibull plot analysis. The Weibull plots were linear for both the FGF-CP and uncoated pin groups. The slope of the regression line was significantly higher in the FGF-CP group (1.7343) than in the uncoated pin group (1.5670) (p = 0.011). The intercept of the regression line was significantly lower in the FGF-CP group (-9.847) than in the uncoated pin group (-8.708) (p = 0.002). Thus, the two regression lines significantly differed. Conclusions: Ti pins coated with FGF-CP layers exhibit the potential to reduce the risk of impaired bone-pin interface strength in the external fixation of distal radius fractures.
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