Language Development Disorders

语言发育障碍
  • 文章类型: Journal Article
    背景:语言延迟会影响幼儿的近期和长期社交交流和学习,and,越来越多的专家关注它。韵律歧视的发展是语言发展的最早阶段之一,掌握了后期阶段的关键技能。因此,分析语言韵律的大脑辨别力与语言能力的关系,可以为语言延迟的诊断和干预提供客观依据。
    方法:在本研究中,所有病例(n=241)均来自三级妇女医院,从2021年到2022年。我们使用功能近红外光谱(fNIRS)来评估儿童的神经韵律辨别能力,并使用中文交际发展清单(CCDI)来评估他们的语言能力。
    结果:在I期和II期研究的最终分析中纳入了98名足月和108名早产幼儿,分别。足月CCDI筛查总异常率为9.2%,早产儿为34.3%。足月幼儿在除通道5外的所有通道中均显示出韵律辨别能力,而早产幼儿仅在通道6中显示出韵律辨别能力。多因素logistic回归分析表明,右角回(通道3)的韵律判别对足月幼儿的语言延迟有统计学意义(奇数比=0.301,P<0.05)。随机森林(RF)回归模型表明,基于fNIRS数据的通道和大脑区域反映的韵律判别是预测早产儿语言延迟的重要参数。其中由右角回(通道4)反映的韵律判别是最重要的参数。模型接收器工作特征(ROC)曲线下面积为0.687。
    结论:神经韵律辨别能力与语言发育呈正相关,通过fNIRS对脑韵律辨别能力的评估可作为未来临床应用中早期识别语言延迟儿童的客观指标.
    BACKGROUND: Language delay affects near- and long-term social communication and learning in toddlers, and, an increasing number of experts pay attention to it. The development of prosody discrimination is one of the earliest stages of language development in which key skills for later stages are mastered. Therefore, analyzing the relationship between brain discrimination of speech prosody and language abilities may provide an objective basis for the diagnosis and intervention of language delay.
    METHODS: In this study, all cases(n = 241) were enrolled from a tertiary women\'s hospital, from 2021 to 2022. We used functional near-infrared spectroscopy (fNIRS) to assess children\'s neural prosody discrimination abilities, and a Chinese communicative development inventory (CCDI) were used to evaluate their language abilities.
    RESULTS: Ninety-eight full-term and 108 preterm toddlers were included in the final analysis in phase I and II studies, respectively. The total CCDI screening abnormality rate was 9.2% for full-term and 34.3% for preterm toddlers. Full-term toddlers showed prosody discrimination ability in all channels except channel 5, while preterm toddlers showed prosody discrimination ability in channel 6 only. Multifactorial logistic regression analyses showed that prosody discrimination of the right angular gyrus (channel 3) had a statistically significant effect on language delay (odd ratio = 0.301, P < 0.05) in full-term toddlers. Random forest (RF) regression model presented that prosody discrimination reflected by channels and brain regions based on fNIRS data was an important parameter for predicting language delay in preterm toddlers, among which the prosody discrimination reflected by the right angular gyrus (channel 4) was the most important parameter. The area under the model Receiver operating characteristic (ROC) curve was 0.687.
    CONCLUSIONS: Neural prosody discrimination ability is positively associated with language development, assessment of brain prosody discrimination abilities through fNIRS could be used as an objective indicator for early identification of children with language delay in the future clinical application.
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  • 文章类型: Journal Article
    发展性语言障碍(DLD)已被解释为由于抽象的代表性缺陷而产生的缺陷,或者由于在获取和协调指导学习的多种相互作用线索方面的困难而出现的缺陷。在对欧洲语言进行测试时,这些相互竞争的解释通常很难在两者之间做出决定。本文报道了在有和没有DLD的广东话儿童中产生相对条款(RC)的实验研究,这使我们能够检验从一个突出的理论-紧急主义中得出的多种发展预测。将患有DLD的儿童(N=22;6岁;6-9岁;7)与年龄匹配的典型发育同龄人(N=23)和语言匹配的儿童进行比较,执行句子重复任务的典型发育儿童(N=21;4岁;7-7岁;6)。结果表明,跨多个RC类型的儿童生产受结构频率的影响,一般语义复杂性,和成分的线性顺序,DLD组的表现比年龄匹配和语言匹配的同龄人差。结果与DLD的紧急解释一致。
    Developmental Language Disorder (DLD) has been explained as either a deficit deriving from an abstract representational deficit or as emerging from difficulties in acquiring and coordinating multiple interacting cues guiding learning. These competing explanations are often difficult to decide between when tested on European languages. This paper reports an experimental study of relative clause (RC) production in Cantonese-speaking children with and without DLD, which enabled us to test multiple developmental predictions derived from one prominent theory - emergentism. Children with DLD (N = 22; aged 6;6-9;7) were compared with age-matched typically-developing peers (N = 23) and language-matched, typically-developing children (N = 21; aged 4;7-7;6) on a sentence repetition task. Results showed that children\'s production across multiple RC types was influenced by structural frequency, general semantic complexity, and the linear order of constituents, with the DLD group performing worse than their age-matched and language-matched peers. The results are consistent with the emergentist explanation of DLD.
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  • 文章类型: Journal Article
    The S3 Guideline on the Treatment of Language Development Disorders: Summary of Recommendations Abstract: The German S3 Guidelines on the Treatment of Developmental Speech and Language Disorders (AWMF: No. 049-015) were published on the AWMF homepage at the end of 2022. The German Society for Phoniatrics and Paedaudiologie coordinated the work and developed the guideline text together with linguists and speech and language therapists. Many scientific medical societies consented to the respective recommendations. For the first time in the German-speaking area, the guideline group reviewed international research results on the treatment of various speech and language disorders and formulated evidence- or consensus-based recommendations for clinical care. The present article summarizes these recommendations and evaluates the guidelines from the perspective of child and adolescent psychiatry and psychotherapy.
    Zusammenfassung: Die S3-Leitlinie zur Therapie von Sprachentwicklungsstörungen (AWMF: Nr. 049-015), die Ende 2022 auf der Homepage der AWMF veröffentlich wurde, ist unter Federführung der Deutschen Gesellschaft für Phoniatrie und Pädaudiologie in Kooperation mit zahlreichen Sprachwissenschaftler_innen und Sprachtherapeut_innen entwickelt und von zahlreichen wissenschaftlichen medizinischen Fachgesellschaften konsentiert worden. Die Leitliniengruppe hat erstmalig für den deutschen Sprachraum versucht, die internationale Studienlage zur Therapie unterschiedlicher Sprach- und Sprechstörungen aufzuarbeiten und darauf basierend Evidenz- oder auch Konsensus-basierte Empfehlungen für die klinische Versorgung zu formulieren. In dem vorliegenden Artikel werden diese Empfehlungen zusammenfassend dargestellt, und es wird eine Wertung der Leitlinie aus Kinder- und Jugendpsychiatrischer Sicht vorgenommen.
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  • 文章类型: Journal Article
    语言障碍,它们仍然很难被检测到,经常出现在受虐待的儿童身上。虽然后果是众所周知的,而且是持久的,对这些孩子的发育和具体特征知之甚少,取决于它们被放置在哪里,他们遭受的虐待类型和他们所处的年龄。这一发现导致了对文献的回顾,旨在更好地定义关于该主题的知识状态,为了更好的检测和治疗。
    Language disorders, which are still very poorly detected, are often present in abused children. While the consequences are well known and long-lasting, little is known about the development and specific characteristics of these children, depending on where they were placed, the type of abuse they suffered and the age at which they were placed. This finding led to a review of the literature aimed at better defining the state of knowledge on the subject, for the benefit of better detection and treatment.
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  • 文章类型: Journal Article
    Language disorders may interfere with social integration and affectpersonal development. Beca-use the balance of the stomatognathic system can interfere with language, it is important for speech therapy and dentistry to work together, providing multidisciplinar y Healthcare.
    To analyze the 100 most frequently cited articles on language disorders in children and adolescents and assess the interplay with dentistry by means of a bibliometric analysis.
    A search of the 100 most frequently cited articles up to December 2021 on language disorders was performed in the Web of Science Core Collection database. Four researchers extracted the data on number of citations, title, authors, country, year of publication, journals, study design, prevalent clinical conditions, and area of expertise. The analyses were performed using VOSviewer and Excel.
    The total number of citations ranged from 251 to 1,431. Four articles were cited more than 1,000 times. Bishop DVM (10 articles; 3,653 citations) and Tomblin JD (10 articles; 4,261 citations) were the most frequently cited authors. The institutions with the largest number of publications were the University of Oxford/England (11%) and the University of Kansas/USA (8%). Observational study design was the most frequent (77%). Autism spectrum disorder (18%) and dyslexia (14%) were the most broadly investigated clinical conditions. Speech-language pathology (32%) was the area of expertise with the largest number of articles, and none of the top 100 studies showed interplay with dentistry.
    The 100 most widely cited articles on language disorders are mostly observational, mainly address autism spectrum disorder, and are in the field of speech-language pathology No study reported interplay with dentistry.
    Os disturbios de linguagem podem interferir na integrando social e afetar o desenvolvimento dos individuos. O trabalho multidisciplinar entre fonoaudiologia e odontologia é muito importante para a promogdo da saúde. O equilibrio do sistema estomatognático interfere na linguagem.
    Analisar os100 artigos mais citados sobre distúrbios de linguagem em criannas e adolescentes e verificar a interando com a odontologia por meio de análise bibliométrica.
    Foi realizada uma busca pelos 100 artigos mais citados sobre distúrbios de linguagem na base de dados Web of Science Core Collection até dezembro de 2021. Quatro pesquisadores extrairam os dados referentes a número de citanoes, titulo, autores, país, ano de publicando, periódicos, desenho de estudo, condinoes clínicas prevalentes e área de especializando. As análises foram realizadas utilizando VOSviewer e Excel.
    O número total de citanoes variou de 251 a 1.431. Quatro artigos foram citados mais de 1.000 vezes. Bishop DVM (10 artigos; 3.653 citanoes) e Tomblin JD (10 artigos; 4.261 citanoes) foram os autores mais frequentemente citados. As instituinoes com maior número de publicanoes foram a Universidade de Oxford/Inglaterra (11%) e a Universidade de Kansas/EUA (8%). O desenho de estudo observacional foi o mais frequente (77%). O transtorno do espectro autista (18%) e a dislexia (14%) foram as condinoes clínicas mais amplamente investigadas. A Fonoaudiologia (32%) foi a área de atuando com maior número de artigos e nenhum estudo, entre os top100, mostrou interando com a Odontologia.
    Os 100 artigos mais citados sobre distúrbios de linguagem sdo em sua maioria observacionais, abordam principalmente transtornos do espectro do autismo e estdo na área de fonoaudiologia. Nenhum estudo apresentou interando com a odontologia.
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  • 文章类型: Journal Article
    我们调查了StoryChamps对患有发育性语言障碍(DLD)的三年级西班牙语-英语双语儿童的口语效果。
    我们实施了并发的多基线跨参与者单例设计,其中有四个具有DLD的西班牙语-英语双语三年级学生。治疗在12个疗程中进行,每周约2个疗程。在干预后1、2和4周进行维持治疗。参与者被明确地教授故事语法元素,因果关系和时间联系,以及故事复述和个人叙述中的修饰语。因变量是故事语法,语法复杂性,故事复述中的修饰语和听力理解,以及个人叙述中的故事语法和语法复杂性。在每个基线结束时评估结果指标,干预,和维护会话使用叙事语言措施-听力(NLM-L)。
    结果测量的视觉分析表明,干预期间NLM-L得分略有增加,并伴有明显的变异性。对故事复述表现的案例分析表明,对两名参与者的故事语法以及对一名参与者的语法复杂性和修饰语使用具有干预作用。对于个人叙述,个人叙事表现的案例内部分析表明,对一名参与者的故事语法有干预作用。
    总的来说,StoryChamps展示了在四分之三的参与者中改善故事重述中故事语法使用的功效。它没有显示出改善语法复杂性的功效,修饰符使用,或者故事中的听力理解,它也没有显示出改善个人叙述中的故事语法和语法复杂性的功效。
    https://doi.org/10.23641/asha.26053033。
    UNASSIGNED: We investigated the efficacy of Story Champs for improving oral language in third-grade Spanish-English bilingual children with developmental language disorder (DLD).
    UNASSIGNED: We implemented a concurrent multiple-baseline across-participants single-case design with four bilingual Spanish-English third-grade students with DLD. Treatment was carried out over 12 sessions with approximately two sessions per week. Maintenance sessions were conducted 1, 2, and 4 weeks postintervention. Participants were explicitly taught story grammar elements, causal and temporal connections, and modifiers within story retells and personal narratives. Dependent variables were story grammar, grammatical complexity, modifiers and listening comprehension within story retells, and story grammar and grammatical complexity within personal narratives. Outcome measures were assessed at the end of every baseline, intervention, and maintenance session using the Narrative Language Measures-Listening (NLM-L).
    UNASSIGNED: Visual analyses for outcome measures suggested slight increases in scores on the NLM-L during intervention accompanied by marked variability. Within-case analyses of story retell performance suggested an intervention effect on story grammar for two participants and on grammatical complexity and modifier use for one participant. For personal narratives, within-case analyses of personal narrative performance suggested an intervention effect on story grammar for one participant.
    UNASSIGNED: Overall, Story Champs demonstrated efficacy for improving story grammar use in story retells for three out of four participants. It did not show efficacy for improving grammatical complexity, modifier use, or listening comprehension within story retells, nor did it show efficacy for improving story grammar and grammatical complexity within personal narratives.
    UNASSIGNED: https://doi.org/10.23641/asha.26053033.
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  • 文章类型: Journal Article
    我们研究了使用以不同剂量递送的SHAPECODING™系统的高度个性化的形态句法干预的有效性。
    8名年龄为8岁的发育性语言障碍儿童;0-10岁;10岁(岁;月)接受了10小时的明确个性化干预,以30分钟的单独疗程进行,每周一次,持续20周。在至少四次基线探针测试之后,每个会话的两个语法目标收到明确的指令,直到它们达到标准(90%),当引入下一个目标时。要控制会话长度和教学片段密度,要么两个目标每节接受20个教学集,要么一个目标接受10个教学集,另一个目标接受30个教学集。还对已完成的目标进行了维护测试。
    干预后的探针测试得分明显高于基线阶段(d=1.6),在基线或维持阶段没有变化。然而,干预阶段的进展非常显著.一名参与者在干预方面表现出明显更快的进展,而一个(注意力得分最低)进展甚微。在考虑相对于累积干预会议的进展时,每节教学30次,进度更快,10次较慢。然而,当累积教学事件被用作预测因子时,所有三个疗程内剂量都显示出非常相似的进展速度,每集教学的正确反应几率增加3.9%。达到的目标平均需要40-60个教学集。
    除一名参与者外,个性化干预是非常有效和高效的。因此,个性化目标识别过程和干预方法值得在更大的儿童群体中进一步研究。跨课程提供的每个目标的累计教学次数似乎是关键。因此,临床医生应该瞄准高教学发作率,特别是如果会话的数量受到限制。否则,干预调度可以是灵活的。
    https://doi.org/10.23641/asha.25996168。
    UNASSIGNED: We investigated the effectiveness of a highly individualized morphosyntactic intervention using the SHAPE CODING™ system delivered at different dosages.
    UNASSIGNED: Eight children with developmental language disorder aged 8;0-10;10 (years;months) received 10 hr of explicit individualized intervention for morphosyntax delivered in 30-min individual sessions once per week for 20 weeks. Following at least four baseline probe tests, two grammatical targets per session received explicit instruction until they reached criterion (90%), when the next target was introduced. To control for session length and teaching episode density, either both targets received 20 teaching episodes per session or one target received 10 teaching episodes and the other 30. Maintenance testing of completed targets was also carried out.
    UNASSIGNED: Scores on probe tests post-intervention were significantly higher than during the baseline phase (d = 1.6) with no change during the baseline or maintenance phases. However, progress during the intervention phase was highly significant. One participant showed significantly faster progress with intervention, while one (with the lowest attention score) made little progress. When considering progress relative to cumulative intervention sessions, progress was faster with 30 teaching episodes per session and slower with 10. However, when cumulative teaching episodes were used as the predictor, all three within-session dosages showed very similar rates of progress, with the odds of a correct response increasing by 3.9% for each teaching episode. The targets that were achieved required an average of 40-60 teaching episodes.
    UNASSIGNED: With the exception of one participant, the individualized intervention was highly effective and efficient. Thus, the individualized target identification process and intervention method merit further research in a larger group of children. The cumulative number of teaching episodes per target provided across sessions appeared to be key. Thus, clinicians should aim for high teaching episode rates, particularly if the number of sessions is constrained. Otherwise, intervention scheduling can be flexible.
    UNASSIGNED: https://doi.org/10.23641/asha.25996168.
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  • 文章类型: Journal Article
    脆性X信使核糖核蛋白-1(FMR1)前突变(FXpm)是一种在普通人群中常见的遗传变异,并与成年后的健康症状和疾病相关。然而,儿童期对临床表型的认识不足阻碍了筛查和干预临床实践指南的制定.鉴于在FXpm的成年人中广泛记录了社会沟通困难,并且与心理社会功能降低有关,本研究旨在表征FXpm在幼儿期的交流特征.
    通过级联测试(89%)或出生时筛查(11%)确定的18名FXpm儿童与21名匹配的典型发育儿童进行了比较,2-4岁。参与者完成了语言(早期学习的Mullen量表)和自适应交流(VinelandAdaptiveBehaviorScales-II)的标准化评估。使用《社会传播变化的简要观察》从半自然主义的互动样本中对社会传播进行了评级。
    FXpm的儿童表现出延迟的社会交往发展,群体差异的大小突出了社会交流,这是一个将FXpm儿童与同龄人区分开来的特征(p=.046,ηp2=.12)。两组在标准化语言和适应性沟通措施上没有差异(ps>.297,ηp2s<.03)。
    早期筛查和治疗社交延迟可能是优化FXpm儿童预后的关键。需要进一步的研究来复制更大样本中的发现,在FXpm中描绘整个生命周期中社会交往困难的轨迹和后果,并确定FMR1作为一般人群中发育沟通差异的中介者的潜在流行病学意义。
    UNASSIGNED: The Fragile X Messenger Ribonucleoprotein-1 (FMR1) premutation (FXpm) is a genetic variant that is common in the general population and is associated with health symptoms and disease in adulthood. However, poor understanding of the clinical phenotype during childhood has hindered the development of clinical practice guidelines for screening and intervention. Given that social communication difficulties have been widely documented in adults with the FXpm and are linked with reduced psychosocial functioning, the present study aimed to characterize the communication profile of the FXpm during early childhood.
    UNASSIGNED: Eighteen children with the FXpm who were identified through cascade testing (89%) or screening at birth (11%) were compared to 21 matched typically developing children, aged 2-4 years. Participants completed standardized assessments of language (Mullen Scales of Early Learning) and adaptive communication (Vineland Adaptive Behavior Scales-II). Social communication was rated from seminaturalistic interaction samples using the Brief Observation of Social Communication Change.
    UNASSIGNED: Children with the FXpm showed delayed social communication development, with the magnitude of group differences highlighting social communication as a feature that distinguishes children with the FXpm from their peers (p = .046, ηp2 = .12). The groups did not differ on the standardized language and adaptive communication measures (ps > .297, ηp2s < .03).
    UNASSIGNED: Early screening and treatment of social communication delays may be key to optimizing outcomes for children with the FXpm. Further research is needed to replicate findings in a larger sample, delineate the trajectory and consequences of social communication difficulties across the life span in the FXpm, and determine the potential epidemiological significance of FMR1 as a mediator of developmental communication differences within the general population.
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  • 文章类型: Journal Article
    我们调查并比较了两个标准化的结果,规范参考的语言筛选评估(即,语言基础学前第二版的临床评估[CELFP-2],语言变异筛查测试[DELV-ST]的诊断评估)对非洲裔美国学龄前儿童的口语方言与普通美国英语(GAE)不同。我们(a)描述了学龄前儿童在CELFP-2核心语言索引(CLI)及其子测试中的表现,并考虑了所观察到的方言变异程度(DVAR),(b)调查了对方言敏感的评分修改对表达形态和语法单词结构(WS)子测试的应用如何影响CELFP-2CLI分数,和(c)评估DELV-ST和CELFP-2CLI之间的筛查分类一致率。
    非裔美国学龄前儿童(N=284)完成了CELFP-2CLI子测试(即,句子结构,WS,表达词汇)和DELV-ST。用DELV-ST第一部分语言变异状态估计了口语方言使用的密度,并计算DVAR的百分比。CELFP-2WS子检验在有和没有方言敏感评分修改的情况下进行评分。
    CELFP-2CLI性能的计划比较表明,基于DELV-ST确定的语言变异分组程度,性能存在统计学上的显着差异。应用于WS子测试的评分修改增加了子测试缩放分数和CLI综合标准分数。然而,表现出GAE强烈变异的学龄前儿童的表现仍然明显低于表现出很少甚至没有语言变异的学龄前儿童。评估(修改和未修改的CELFP-2CLI评分和DELV-ST第II部分诊断风险状态)之间的受影响状态一致率极低。
    将方言特定的评分修改应用于标准化,规范引用的语言评估必须同时通过公平的视角来看待,实用性,和心理测量。我们的多阶段研究结果重申,需要可靠的方法来识别说GAE以外的美国英语方言的儿童中发育性语言障碍的风险。
    https://doi.org/10.23641/asha.26017978。
    UNASSIGNED: We investigated and compared the outcomes from two standardized, norm-referenced screening assessments of language (i.e., Clinical Evaluation of Language Fundamentals Preschool-Second Edition [CELFP-2], Diagnostic Evaluation of Language Variation-Screening Test [DELV-ST]) with African American preschoolers whose spoken dialect differed from that of General American English (GAE). We (a) described preschoolers\' performance on the CELFP-2 Core Language Index (CLI) and its subtests with consideration of degree of dialect variation (DVAR) observed, (b) investigated how the application of dialect-sensitive scoring modifications to the expressive morphology and syntax Word Structure (WS) subtest affected CELFP-2 CLI scores, and (c) evaluated the screening classification agreement rates between the DELV-ST and the CELFP-2 CLI.
    UNASSIGNED: African American preschoolers (N = 284) completed the CELFP-2 CLI subtests (i.e., Sentence Structure, WS, Expressive Vocabulary) and the DELV-ST. Density of spoken dialect use was estimated with the DELV-ST Part I Language Variation Status, and percentage of DVAR was calculated. The CELFP-2 WS subtest was scored with and without dialect-sensitive scoring modifications.
    UNASSIGNED: Planned comparisons of CELFP-2 CLI performance indicated statistically significant differences in performance based on DELV-ST-determined degree of language variation groupings. Scoring modifications applied to the WS subtest increased subtest scaled scores and CLI composite standard scores. However, preschoolers who demonstrated strong variation from GAE continued to demonstrate significantly lower performance than preschoolers who demonstrated little to no language variation. Affected-status agreement rates between assessments (modified and unmodified CELFP-2 CLI scores and DELV-ST Part II Diagnostic Risk Status) were extremely low.
    UNASSIGNED: The application of dialect-specific scoring modifications to standardized, norm-referenced assessments of language must be simultaneously viewed through the lenses of equity, practicality, and psychometry. The results of our multistage study reiterate the need for reliable methods of identifying risk for developmental language disorder within children who speak American English dialects other than GAE.
    UNASSIGNED: https://doi.org/10.23641/asha.26017978.
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  • 文章类型: Journal Article
    背景:儿童的言语和语言延迟会导致社交互动问题,注意困难,阅读和阅读能力下降,认知和行为发育不良。尽管埃塞俄比亚的言论和语言延误越来越普遍,缺乏有关导致这种延迟的因素的文献。因此,这项研究旨在确定亚的斯亚贝巴Yekatit12医院12个月至12岁儿童的言语和语言延迟的决定因素,埃塞俄比亚。
    方法:我们在Yekatit12医院进行了一项基于机构的研究,无匹配的病例对照研究,包括50例病例和100例12个月至12岁的对照。使用面试官管理的问卷从参与儿童的父母或照顾者那里收集数据。EpiInfov7用于样本计算,采用SPSSv26进行分析。进行卡方检验以确定言语和语言延迟之间的关系以及确定因素,然后进行逻辑回归。根据调整后的优势比(AOR)确定显著的决定因素,95%CI和p值(<0.05)。
    结果:病例组男性23例,女性27例,共50名儿童。完成多变量分析后,出生窒息[AOR=4.58,95CI(1.23-16.99)],奶瓶喂养[AOR=4.54,95CI(1.29-16.04)],母子分离[AOR=2.6,95CI(1.05-6.43)],多语种家庭[AOR=2.31,95CI(1.03-5.18)],和屏幕时间大于2小时[AOR=3.06,95CI(1.29-7.28)]被发现是言语和语言延迟的统计学显著决定因素。
    结论:我们的研究发现出生窒息,奶瓶喂养,母子分离,来自多语种家庭,过多的屏幕时间会显著导致语音和语言延迟。因此,重要的是制定针对这些可改变因素的干预措施,同时确保早期诊断和治疗方案易于获得。
    BACKGROUND: Speech and language delay among children can result in social interaction problems, attention difficulties, decreased writing and reading abilities, and poor cognitive and behavioral development. Despite the mounting prevalence of speech and language delays in Ethiopia, there is a lack of literature addressing the factors contributing to this delay. Consequently, this study aims to identify determinants of speech and language delay among children aged 12 months to 12 years at Yekatit 12 Hospital in Addis Ababa, Ethiopia.
    METHODS: We conducted an institutional-based at Yekatit 12 Hospital, unmatched case-control study with 50 cases and 100 controls aged 12 months to 12 years. Interviewer-administered questionnaires were used to collect data from the parents or caregivers of the participating children. Epi Info v7 was used for sample calculation, and SPSS v26 was used for analysis. The chi-square test was performed to determine the relationship between speech and language delay and determining factors, which was then followed by logistic regression. The significant determining factors were identified based on the adjusted odds ratio (AOR), with a 95% CI and p-value (< 0.05).
    RESULTS: Case group constituted 23 males and 27 females, totaling 50 children. Upon completing the multivariate analysis, birth asphyxia [AOR = 4.58, 95CI (1.23-16.99)], bottle-feeding [AOR = 4.54, 95CI (1.29-16.04)], mother-child separation [AOR = 2.6, 95CI (1.05-6.43)], multilingual family [AOR = 2.31, 95CI (1.03-5.18)], and screen time greater than two hours [AOR = 3.06, 95CI (1.29-7.28)] were found to be statistically significant determinants of speech and language delay.
    CONCLUSIONS: Our study found that birth asphyxia, bottle-feeding, mother-child separation, being from a multilingual family, and excessive screen time contribute significantly to speech and language delay. As a result, it is important to develop interventions that target these modifiable factors, while also ensuring that early diagnosis and treatment options are readily accessible.
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