化脓性汗腺炎(HS)是一种慢性炎症性皮肤病,通常会导致生活质量下降。先前的研究评估与HS患者的污名化有关的压力和歧视是有限的。这项研究的目的是检查HS与以下与心理健康相关的因素之间的关联:压力,歧视,和孤独。我们对2024年3月在美国国立卫生研究院的“我们所有人”研究计划中注册的18岁及以上的参与者进行了二次分析。研究样本仅限于完成4项心理社会幸福感调查中≥1项的个体。在1,352名HS患者中,135个样本。在208,290名没有HS的人中,包括56,902。以下调查评估了孤独感,压力,在日常环境中感知到的歧视,以及在医疗环境中感知到的歧视,分别:加州大学洛杉矶分校孤独量表,科恩感知压力量表,日常歧视量表,和医疗环境中的歧视量表。HS和调查得分之间的关联是使用多变量线性回归进行建模的,自我报告的种族和种族,年龄,和收入。在未调整的模型中,HS患者的应激程度明显更高(MeanHS(SD)=21.5(4.74);Meannon-HS(SD)=19.8(3.98);p<0.001),日常环境中的歧视(MeanHS(SD)=18.9(8.16);Meannon-HS(SD)=16.0(7.06);p<0.0001),和医疗保健环境中的歧视(MeanHS(SD)=1.77(0.64);Meannon-HS(SD)=1.56(0.62);p<0.001)。在适应性爱之后,种族,年龄,和收入,在医疗机构中,HS与歧视之间的关联并不显著;然而,HS与感知压力水平增加和日常歧视之间的关联仍然很重要.调查完成率低以及完成和未完成研究调查的人之间的人口统计学差异可能会限制结果的普遍性。研究结果表明,患有HS的人可能会从定期筛查社会心理健康和提供支持资源中受益。
Hidradenitis suppurativa (HS) is a chronic inflammatory cutaneous disease that often leads to decreased quality of life. Prior research assessing stress and
discrimination related to stigmatization of those with HS is limited. The aim of this study was to examine the association between HS and the following factors related to psychosocial well-being: stress, discrimination, and loneliness. We performed secondary analysis of participants 18 years and older registered in the National Institutes of Health\'s All of Us Research Program in March 2024. The study sample was limited to individuals who had completed ≥ 1 of 4 psychosocial well-being surveys. Among 1,352 individuals with HS, 135 were included in the sample. Among 208,290 individuals without HS, 56,902 were included. The following surveys assessed loneliness, stress, perceived
discrimination in everyday settings, and perceived
discrimination in medical settings, respectively: the UCLA Loneliness Scale, Cohen Perceived Stress Scale, Everyday
Discrimination Scale, and
Discrimination in Medical Settings Scale. The association between HS and survey scores was modeled using multivariable linear regression adjusted for self-reported sex, self-reported race and ethnicity, age, and income. In an unadjusted model, those with HS reported a significantly higher degree of stress (MeanHS (SD) = 21.5 (4.74); Meannon-HS (SD) = 19.8 (3.98); p < 0.001), discrimination in everyday settings (MeanHS (SD) = 18.9 (8.16); Meannon-HS (SD) = 16.0 (7.06); p < 0.0001), and discrimination in healthcare settings (MeanHS (SD) = 1.77 (0.64); Meannon-HS (SD) = 1.56 (0.62); p < 0.001). After adjusting for sex, race, age, and income, the association between HS and
discrimination in healthcare settings was non-significant; however, associations between HS and increased levels of perceived stress and everyday discrimination remained significant. Low survey completion rates and demographic differences between those who did and did not complete the study surveys may limit generalizability of results. Findings suggest that those with HS may benefit from regular screening for psychosocial well-being and provision of support resources.