technical guidelines

技术准则
  • 文章类型: Journal Article
    磁共振引导聚焦超声(MRgFUS)是一种完全非侵入性的技术,已被FDA批准用于治疗多种疾病。这份报告,由美国医学物理学家协会(AAPM)任务组241编写,提供了MRgFUS技术的背景,重点是临床机构MRgFUS系统。该报告解决了医学物理学界感兴趣的问题,特定于车身MRgFUS系统配置,并就如何成功实施和维持临床MRgFUS计划提供建议.以下部分描述了典型MRgFUS系统和临床工作流程的关键特征,并为医学物理学家提供了关键点和最佳实践。常用的术语,定义了度量和物理学,并描述了影响MRgFUS程序的不确定性来源。最后,说明了安全和质量保证程序,描述了医学物理学家在MRgFUS程序中的推荐角色,和规划临床试验的监管要求是详细的。尽管本报告的范围仅限于在美国批准或目前正在进行临床试验的临床机构MRgFUS系统,提供的许多材料也适用于为其他应用设计的系统。
    Magnetic resonance-guided focused ultrasound (MRgFUS) is a completely non-invasive technology that has been approved by FDA to treat several diseases. This report, prepared by the American Association of Physicist in Medicine (AAPM) Task Group 241, provides background on MRgFUS technology with a focus on clinical body MRgFUS systems. The report addresses the issues of interest to the medical physics community, specific to the body MRgFUS system configuration, and provides recommendations on how to successfully implement and maintain a clinical MRgFUS program. The following sections describe the key features of typical MRgFUS systems and clinical workflow and provide key points and best practices for the medical physicist. Commonly used terms, metrics and physics are defined and sources of uncertainty that affect MRgFUS procedures are described. Finally, safety and quality assurance procedures are explained, the recommended role of the medical physicist in MRgFUS procedures is described, and regulatory requirements for planning clinical trials are detailed. Although this report is limited in scope to clinical body MRgFUS systems that are approved or currently undergoing clinical trials in the United States, much of the material presented is also applicable to systems designed for other applications.
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  • 文章类型: Journal Article
    The main focus of the presented study is a multi-variant accuracy assessment of a photogrammetric 2D and 3D data collection, whose accuracy meets the appropriate technical requirements, based on the block of 858 digital images (4.6 cm ground sample distance) acquired by Trimble® UX5 unmanned aircraft system equipped with Sony NEX-5T compact system camera. All 1418 well-defined ground control and check points were a posteriori measured applying Global Navigation Satellite Systems (GNSS) using the real-time network method. High accuracy of photogrammetric products was obtained by the computations performed according to the proposed methodology, which assumes multi-variant images processing and extended error analysis. The detection of blurred images was preprocessed applying Laplacian operator and Fourier transform implemented in Python using the Open Source Computer Vision library. The data collection was performed in Pix4Dmapper suite supported by additional software: in the bundle block adjustment (results verified using RealityCapure and PhotoScan applications), on the digital surface model (CloudCompare), and georeferenced orthomosaic in GeoTIFF format (AutoCAD Civil 3D). The study proved the high accuracy and significant statistical reliability of unmanned aerial vehicle (UAV) imaging 2D and 3D surveys. The accuracy fulfills Polish and US technical requirements of planimetric and vertical accuracy (root mean square error less than or equal to 0.10 m and 0.05 m).
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  • 文章类型: Comparative Study
    The European Society of Gastrointestinal Endoscopy (ESGE) has recently issued a technical review focused on small bowel capsule endoscopy (SBCE).
    To compare SBCE current practice in Italy to ESGE technical recommendations.
    A dedicated per-centre semi-quantitative questionnaire was prepared by a group of SBCE experts. One-hundred-fifty Centres were invited to participate in the data collection concerning SBCEs performed between June 2016 and June 2017. Data were compared with ESGE recommendations.
    120 Centres participated in the data collection. Current practices agreed with ESGE recommendations in 56.3% (9/16) of the issues evaluated. Differences between ESGE recommendations and current practice concerned the management of patients with pacemakers or cardiac implantable defibrillators (which was in agreement with ESGE recommendations in 31.7% and 15.8% of Centres, respectively), the SBCE setting (only 51% of SBCEs were performed as outpatients procedures), the assessment of capsule excretion (timing and modality were in agreement with ESGE recommendation in 20.0% of Centres), and in the involvement of trained nurses or fellows in training as pre-readers (7/120; 5.8%).
    Although SBCE is widely used and largely available in Italy, there are still some technical, practical and organizational issues that can be modified to bridge the gap between current practice and ESGE guideline recommendations.
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  • 文章类型: Journal Article
    这篇评论的重点是使病虫害综合管理(IPM)的原始概念适应欧洲实施的综合水果生产(IFP)的更广泛概念的过程。尽管大多数害虫管理策略仍然依赖于使用合成农药,现在有各种各样的创新和环保工具可以替代现代苹果生产系统中的农药。我们还强调了最近的虫害管理策略和工具如何为IPM改进研究创造了机会,包括使用生物杀虫剂,化学信息素和生物防治。预测模型,还开发了新的树木训练系统和创新的喷雾设备,以提高治疗覆盖率,减轻农药漂移和减少水果上的化学残留物。还审查了危害有效实施IPM的可能威胁,特别是与农药抗性的发展和新的入侵性害虫的引入有关的风险。根据第128/09号指令,欧洲立法将IPM视为可持续使用农药的战略方法。在此背景下,IPM和相关指南被称为满足与工人和旁观者安全有关的不同领域的关注。除了以市场为导向的农业的传统经济标准,可持续农业包括评估农艺实践在其发生的社会背景下对环境的影响。由于消费者对水果生产产生的环境影响的担忧,IFP认证超过产品标准,包括过程方面,是消费者和连锁超市经常需要的。
    This review focuses on the process of adapting the original concept of Integrated Pest Management (IPM) to the wider conception of the Integrated Fruit Production (IFP) implemented in Europe. Even though most of the pest management strategies still rely on the use of synthetic pesticides, a wide array of innovative and environmentally friendly tools are now available as possible alternative to the pesticides within the modern apple production system. We also highlight how recent pest management strategies and tools have created an opening for research towards IPM improvement, including the use of biorational pesticides, semiochemicals and biological control. Forecasting models, new tree training systems and innovative spray equipment have also been developed to improve treatment coverage, to mitigate pesticide drift and to reduce chemical residues on fruits. The possible threats that jeopardize the effective implementation of IPM and particularly the risks related to the development of the pesticide resistance and the introduction of new invasive pests are also reviewed. With the directive 128/09, the European legislation recognizes IPM as a strategic approach for the sustainable use of pesticides. Within this context, IPM and related guidelines is called to meet different areas of concern in relation to the worker and bystander safety. Beside the traditional economic criteria of the market-oriented agriculture, sustainable agriculture includes the assessment of the environmental impact of the agronomic practices within the societal context where they take place. As a consequence of the raising consumer concerns about environmental impacts generated by the fruit production, IFP certification over product standards, including process aspects, are frequently required by consumers and supermarket chains.
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